scholarly journals Trends in Pancreatic Cancer Incidence and Mortality in Lithuania, 1998–2015

2022 ◽  
Vol 19 (2) ◽  
pp. 949
Author(s):  
Povilas Kavaliauskas ◽  
Audrius Dulskas ◽  
Inga Kildusiene ◽  
Rokas Arlauskas ◽  
Rimantas Stukas ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Incidence ◽  
Direct Method ◽  
Tnm Classification ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Entire Study ◽  
Cancer Of The Pancreas ◽  
Incidence And Mortality ◽  
First Time

Background: Pancreatic cancer is one of the deadliest cancers worldwide, and its incidence is increasing. The aim of this study was to examine the time trends in the incidence and mortality rates of pancreatic cancer for the period of 1998–2015 for the first time in Lithuania by sex, age, subsite, and stage. Methods: This study was based on all cases (deaths) of pancreatic cancer diagnosed between 1998 and 2015. Age-standardized incidence (mortality) rates and group-specific rates were calculated for each sex using the direct method (European Standard). TNM classification-based information reported to the cancer registry was grouped into three categories: (1) localized cancer: T1-3/N0/M0; (2) cancer with regional metastasis: any 1-3/N+/M0; (3) advanced cancer: any T/any N/M+. Joinpoint regression was used to provide annual percentage changes (APCs) and to detect points in time where statistically significant changes in the trends occurred. Results: Overall, 8514 pancreatic cancer cases (4364 in men and 3150 in women) were diagnosed and 7684 persons died from cancer of the pancreas. Pancreatic cancer incidence rates were considerably lower for women than for men, with a female:male ratio of 1:2. Incidence rates changed during the study period from 14.2 in 1998 to 15.0/100,000 in the year 2015 in men, and from 6.7 to 9.8/100,000 in women. Incidence rates over the study period were stable for men (APC = 0.1%) and increasing for women by 1.1% per year. Similarly, mortality rates increased in women by 0.9% per year, and were stable in men. During the study period, incidence and mortality rates of pancreatic cancer were close. For the entire study period, rates increased significantly in the 50–74 years age group; only cancer of the head of pancreas showed a decline by 0.9%, while tail and not-specified pancreatic cancer incidence increased by 11.4% and 4.51%, respectively. Conclusions: The increasing pancreatic cancer incidence trend in the Lithuanian population may be related to the prevalence of its main risk factors (smoking, obesity, physical inactivity, diet, and diabetes).

scholarly journals LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA

2021 ◽  
Vol 20 (4) ◽  
pp. 30-38
Author(s):  
A. A. Mordovskii ◽  
A. A. Aksarin ◽  
A. M. Parsadanyan ◽  
M. D. Ter-Ovanesov ◽  
P. P. Troyan
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Mortality Rate ◽  
Cancer Incidence ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Lung Cancer Incidence ◽  
Cross Correlation Analysis ◽  
Incidence And Mortality ◽  
Khanty Mansi Autonomous

The aim of the study was to assess the lung cancer incidence and mortality in the Khanty-mansi autonomous okrug – Yugra during the period 1999–2019.Material and methods. We have studied the lung cancer incidence and mortality rates in Yugra over the last 21 years (1999–2019).Results. In Yugra, the lung cancer (lc) incidence rates increased by 24.7 % from 1999 to 2019, demonstrating higher rates than those in the Russian Federation (RF), where lc incidence rates decreased by 20.3 %. In 2019, the age-standardized incidence rate was 30.5 per 100,000 (22.7 for RF); the age-standardized mortality rate was 16.4 per 100,000 (18.4 for RF). The mortality rate from lc in Yugra was 9.6 times higher in males than in females (35.5 vs. 3.7 per 100,000). The cross-correlation analysis revealed a correlation between the lc incidence/mortality and air pollution in Yugra. The main carcinogens in Yugra were formaldehyde, phenol, nitrogen dioxide, and benzapyrene. The assessment of the relationship between the age-standardized lc incidence/mortality rates and the amount of pollutants emitted into the atmosphere revealed that their synergistic effects with tobacco smoking can double the risk of lung cancer development. The increase in the number of chest computed tomography (ct) scans performed in the context of the pandemic caused by covid-19 infection led to an 18 % increase in the number of incidentally detected pulmonary nodules, of which 9 % of cases were diagnosed as lc.Conclusion. The lc incidence rates in Yugra tended to increase. The high rate of lc incidence is caused by man-made and natural factors, which requires the implementation of a screening program with the use of low-dose computed tomography in order to improve the early detection and prevention of this disease.

Gastrointestinal cancer mortality rate global trends over the last century.

2021 ◽  
Vol 39 (3_suppl) ◽  
pp. 457-457
Author(s):  
Ravina Sidhu ◽  
Perneet Powar ◽  
Ritu Priya Calla ◽  
Dinesh Vyas
Keyword(s):  
Pancreatic Cancer ◽  
Mortality Rate ◽  
Cancer Incidence ◽  
Cancer Mortality ◽  
Meat Consumption ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Meat Production ◽  
Global Trends ◽  
The Usa

457 Gastrointestinal Cancer Mortality Rate Global Trends Over the Last Century Background: Global gastroenterology cancer mortality trends have drastically changed over past decades due to alterations in risk factors such as diet, populations, exposures, and medical advancements. This study investigates specifically how meat consumption, the biggest evolving risk factor for GI cancer mortality, has influenced various gastrointestinal incidence rates globally. Although the correlation between meat consumption and cancer risk has been investigated, a global temporal study investigating the national mortality rates of gastrointestinal cancers relating to meat production remains unexplored. We researched causes for the trends between meat production and GI cancer mortality in the USA, Canada, Japan, France, and Singapore. Methods: Cancer mortality data was collected from the WHO Cancer Mortality Database, specifically the IARC database. Meat consumption data was unavailable between the 1960s-2010, so meat production data was used and obtained from the FAOSTAT. Results: The pancreatic cancer mortality rate increased in each country except Canada. This spike is due to increased meat consumption, obesity, lack of screening modalities, poor prognosis, and late diagnosis of the disease. Canada’s 1% drop in mortality rate can be attributed to a decreased smoking rate amongst men (62% to 16% from 1965-2017) as well as a decline in meat consumption. The mortality rates of gastric and colorectal cancer (CRC) have decreased despite a meat production increase. Decreased H. pylori prevalence (Europe: 48.8% to 39.8%, North America: 42.4% to 26.6%, and Western Asia: 53.6% to 54.3%) , better food preservation, and improvement in environmental conditions have lowered gastric cancer incidence. The CRC mortality rate in the USA, Canada, Japan, and France decreased mostly due to colonoscopy screening measures, better treatment, and decreased red meat consumption. In Singapore, increased obesity and high caloric diets account for an increased CRC mortality rate despite decreased meat production. This rate is exacerbated by lower screening rates due to decreased CRC risk awareness. Conclusions: Gastric and CRC mortality rates decreased despite increased meat production, while pancreatic cancer incidence rates have increased. These trends are further investigated and necessary to understand to lower the mortality rates of GI cancers on a global scale.

scholarly journals Trends in Incidence and Mortality of Primary Liver Cancer in Lithuania 1998–2015

2021 ◽  
Vol 18 (3) ◽  
pp. 1191
Author(s):  
Audrius Dulskas ◽  
Povilas Kavaliauskas ◽  
Kestutis Zagminas ◽  
Ligita Jancoriene ◽  
Giedre Smailyte
Keyword(s):  
Liver Cancer ◽  
Cancer Incidence ◽  
Ductal Carcinoma ◽  
Primary Liver Cancer ◽  
Age Groups ◽  
Developed Countries ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Incidence And Mortality ◽  
Cancer Incidence Rates

Background: Recently, reports have suggested that rates of liver cancer have increased during the last decades in developed countries; increasing hepatocellular carcinoma and cholangiocarcinoma rates were reported. The aim of this study was to examine time trends in incidence and mortality rates of liver cancer for the period of 1998–2015 in Lithuania by sex, age, and histology. Methods: We examined the incidence of liver cancer from 1998 to 2015 using data from the Lithuanian Cancer Registry. Age-standardized incidence rates were calculated by sex, age, and histology. Trends were analyzed using the Joinpoint Regression Program to estimate the annual percent change. Results: A total of 3086 primary liver cancer cases were diagnosed, and 2923 patients died from liver cancer. The total number of liver cancer cases changed from 132 in 1998 to 239 in 2015. Liver cancer incidence rates changed during the study period from 5.02/100,000 in 1998 to 10.54/100,000 in 2015 in men and from 2.43/100,000 in 1998 to 6.25/100,000 in 2015 in women. Annual percentage changes (APCs) in the age-standardized rates over this period were 4.5% for incidence and 3.6% for mortality. Hepatocellular cancer incidence rates were stable from 1998 to 2005 (APC −5.9, p = 0.1) and later increased by 6.7% per year (p < 0.001). Intrahepatic ductal carcinoma incidence increased by 8.9% per year throughout the study period. The rise in incidence was observed in all age groups; however, in age groups < 50 and between 70 and 79 years, observed changes were not statistically significant. For mortality, the significant point of trend change was detected in 2001, where after stable mortality, rates started to increase by 2.4% per year. Conclusions: Primary liver cancer incidence and mortality increased in both sexes in Lithuania. The rise om incidence was observed in both sexes and main histology groups. The increasing incidence trend may be related to the prevalence of main risk factors (alcohol consumption, hepatitis B and C infections. and diabetes).

Changing Trends in Vulvar Cancer Incidence and Mortality Rates in Australia Since 1982

2015 ◽  
Vol 25 (9) ◽  
pp. 1683-1689 ◽  
Author(s):  
Ellen L. Barlow ◽  
Yoon-Jung Kang ◽  
Neville F. Hacker ◽  
Karen Canfell
Keyword(s):  
Older Women ◽  
Cancer Incidence ◽  
Vulvar Cancer ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Cancer Statistics ◽  
Younger Women ◽  
Changing Trends ◽  
Incidence And Mortality ◽  
Rate Ratios

BackgroundThe objective of this study was to assess trends in vulvar cancer incidence and mortality in Australia.MethodsCase numbers for invasive carcinoma of the vulva (1982–2009) and vulvar cancer deaths (1982–2011) were obtained from the National Cancer Statistics database. Standardized rate ratios (SRRs) were used to assess changes in age-standardized incidence and mortality rates, for all ages and for younger than 60 years and 60+ years.ResultsAge-standardized incidence rates in women across all ages did not significantly change from 1982–1984 to 2007–2009 (from 2.1 to 2.5 per 100,000 women; SRR from the later to the earlier period, 1.13 [95% CI, 1.00–1.27]). However, there was a significant 84% increase in incidence in women younger than 60 years (SRR, 1.84 [95% CI, 1.49–2.26]), with no change for women 60+ years (SRR, 0.90 [95% CI, 0.79–1.04]). Age-standardized mortality in women across all ages significantly decreased by 22% from 1982–1986 to 2007–2011 (from 0.7 to 0.5 per 100,000 women; SRR, 0.78 [95% CI, 0.66–0.93]). However, this was driven by declines in older women, with stable rates in women younger than 60 years (SRR, 1.05 [95% CI, 0.62–1.79]); rates in 60+ years decreased by 24% (SRR, 0.76 [95% CI, 0.63–0.91]).ConclusionSince the early 1980s, vulvar cancer incidence has increased by more than 80% in women younger than 60 years in Australia, but there has been no increased incidence in older women. These findings are consistent with the possibility of increased exposure to the human papillomavirus in cohorts born after 1950. By contrast, age-standardized vulvar cancer mortality rates have been stable in younger women, but have declined in older women.

scholarly journals Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2017

2020 ◽  
Vol 52 (2) ◽  
pp. 335-350 ◽  
Author(s):  
Seri Hong ◽  
Young-Joo Won ◽  
Young Ran Park ◽  
Kyu-Won Jung ◽  
Hyun-Joo Kong ◽  
...  
Keyword(s):  
Cancer Incidence ◽  
Temporal Trends ◽  
Survival Rates ◽  
Relative Survival ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Comprehensive Cancer Control ◽  
Dramatic Improvement ◽  
Cancer Statistics ◽  
Incidence And Mortality

PurposeThis study reports the cancer statistics and temporal trends in Korea on a nationwide scale, including incidence, survival, prevalence, and mortality in 2017.Materials and MethodsThe incidence, survival, and prevalence rates of cancer were evaluated using data from the Korea National Cancer Incidence Database from 1999 to 2017 with follow-up until December 31, 2018. Deaths from cancer were assessed using cause-of-death data from 1983 to 2017, obtained from Statistics Korea. Crude and age-standardized rates (ASRs) for incidence, mortality, and prevalence, and 5-year relative survival rates were calculated and trend analysis was performed.ResultsIn 2017, newly diagnosed cancer cases and deaths from cancer numbered 232,255 (ASR, 264.4 per 100,000) and 78,863 (ASR, 76.6 per 100,000), respectively. The overall cancer incidence rates increased annually by 3.5% from 1999 to 2011 and decreased by 2.7% annually thereafter. Cancer mortality rates have been decreasing since 2002, by 2.8% annually. The 5-year relative survival rate for all patients diagnosed with cancer between 2013 and 2017 was 70.4%, which contributed to a prevalence of approximately 1.87 million cases by the end of 2017.ConclusionThe burden of cancer measured by incidence and mortality rates have improved in Korea, with the exception of a few particular cancers that are associated with increasing incidence or mortality rates. However, cancer prevalence is increasing rapidly, with the dramatic improvement in survival during the past several years. Comprehensive cancer control strategies and efforts should continue, based on the changes of cancer statistics.

scholarly journals The relationship between urologic cancer outcomes and national Human Development Index: trend from 2012 to 2018

2019 ◽  
Author(s):  
Nan Zhang ◽  
Hua Mu ◽  
Yan-rou Jiang ◽  
Shi-geng Zhang
Keyword(s):  
Prostate Cancer ◽  
Cancer Incidence ◽  
Survival Rates ◽  
Substantial Reduction ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Cancer Outcomes ◽  
Net Survival ◽  
Incidence And Mortality ◽  
Urologic Cancer

Abstract Objectives To describe the influence of the socioeconomic development on worldwide age-standardized incidence and mortality rates, as well as mortality-to-incidence ratio (MIR) and 5-year net survival of urologic cancer patients from 2012 to 2018. Methods The HDI values were obtained from the United Nations Development Programme, data on age-standardized incidence/mortality rates of prostate, bladder and kidney cancer were retrieved from the GLOBOCAN database, 5-year net survival was provided by the CONCORD-3 program. We then evaluated the association between incidence/MIR/survival and HDI, with a focus on geographic variability as well as temporal patterns during the last 6 years. Results Urologic cancer incidence rates were positively correlated with HDIs, and MIRs were negatively correlated with HDIs. Prostate cancer survival also correlated positively with HDIs, solidly confirming the interrelation among cancer indicators and socioeconomic factors. Most countries experienced incidence decline over the most recent 6 years, and a substantial reduction in MIR was observed. Survival rates of prostate cancer have simultaneously improved. Conclusion Development has a prominent influence on urologic cancer outcomes. HDI values are significantly correlated with cancer incidence, MIR and survival rates. HDI values have risen along with increased incidence and improved outcomes of urologic caner in recent years.

scholarly journals Trends in the incidence and mortality of kidney cancer in Lithuania from 1993 to 2012

2019 ◽  
Vol 25 (3) ◽  
pp. 151-160
Author(s):  
Aušvydas Patašius ◽  
Agnė Ulytė ◽  
Albertas Ulys ◽  
Giedrė Smailytė
Keyword(s):  
Kidney Cancer ◽  
Cancer Incidence ◽  
Early Stage ◽  
Direct Method ◽  
Incidence Rates ◽  
Treatment Modalities ◽  
Joinpoint Regression ◽  
Mortality Trend ◽  
Incidence And Mortality ◽  
Reduction Of Mortality

Background. The aim of this paper is to analyse trends of kidney cancer incidence and mortality in Lithuania during the period of 1993 to 2012 using joinpoint regression models with special attention to changes in the distribution of stages. Materials and methods. The study was based on all cases of kidney cancer reported to the Lithuanian Cancer Registry between 1993 and 2012. Age group-specific rates and standardized rates were calculated for each sex, using the direct method (world standard population). The joinpoint regression model was used to provide the estimated annual percentage change and to detect points in time where significant changes in the trends occur. Results. During the study period the age-standardized incidence rates increased from 16.89/100,000 in 1993 to 27.77/100,000 in 2012 in males, and from 7.95/100,000 to 13.44/100,000 in females. During this period, annual percentage changes in the age-standardized rates were 2.33% and 1.81% for males and females, respectively. The joinpoint analysis by stage of disease showed the highest increase in stage I kidney cancer, with statistically significant trend change in 2002 for males and in 2001 for females. During the study period, age-standardized mortality rates decreased from 10.42/100,000 in 1993 to 8.96/100,000 in 2012 in males, and from 4.54/100,000 to 3.9/100,000 in females. Conclusions. The kidney cancer incidence rate in Lithuania rose during the period of 1993 to 2012. The detailed analysis by stage showed the most significant increase in organ-confined incidence of kidney cancer. A stable mortality trend for males and a decreasing mortality trend for females along with increased incidence of early stage kidney cancer indicate that both earlier detection and modern treatment modalities may contribute to the reduction of mortality.

Epidemiology of the Incidence and Mortality of Pancreas Cancer and its Relationship with the Human Development Index (HDI) in the World: An Ecological Study in 2018

2020 ◽  
Vol 26 (40) ◽  
pp. 5163-5173
Author(s):  
Elham Goodarzi ◽  
Ali Hassanpour Dehkordi ◽  
Reza Beiranvand ◽  
Hasan Naemi ◽  
Zaher Khazaei
Keyword(s):  
Pancreatic Cancer ◽  
Human Development ◽  
Cancer Incidence ◽  
Pancreas Cancer ◽  
Malignant Neoplasm ◽  
Developed Countries ◽  
Mortality Rates ◽  
Incidence And Mortality ◽  
The Impact ◽  
Very High

Objective: Pancreatic cancer is one of the leading causes of mortality in developed countries and a lethal malignant neoplasm worldwide. This study aims to evaluate the epidemiology of pancreatic cancer incidence and mortality and its relationship with HDI. Methods: This is a descriptive cross-sectional study that is based on cancer incidence data and cancer mortality rates derived from the GLOBOCAN in 2018. : The incidence and mortality rates of Pancreas as well as Pancreas cancer distribution maps were derived for world countries. The data analysis was conducted using a correlation test, and regression tests were used to evaluate the correlation of the incidence and mortality of Pancreas with HDI. The statistical analysis was carried out by Stata-14, and a significance level of 0.05 was considered. Results: The highest incidence of pancreatic cancer was reported in Asia with 214499 (46.7%) cases and the lowest incidence was related to Oceania with 4529 cases (0.99%). The results showed a positive and significant correlation between incidence (r = 0.764, P <0.0001) and mortality (r = 0.771, P <0.0001) of pancreatic cancer and the HDI index. The results of ANOVA revealed that the highest mean incidence was related to the very high HDI (P <0.0001) and the highest mortality was connected to the very high human development (P <0.0001). The results exhibited that incidence was positively and significantly correlated with GNI (r = 0.497, P <0.0001), MYS (r = 0.746, P <0.0001), LEB (r = 0.676, <0.0001) and EYS (r = 0.738, P <0.0001). Also, a significant positive correlation was found between mortality and GNI (r = 0.507, P <0.0001), MYS (r = 0.745, P <0.0001), LEB (r = 0.679, <0.0001), and EYS (r = 0.748, P <0.0001). Conclusion: Given the higher incidence and mortality of pancreatic cancer in countries with HDI, it is necessary to pay a greater attention to risk factors and appropriate planning to reduce these factors and minimize the impact and mortality rate of this disease.

Association Between Cancer Incidence and Mortality in Web-Based Data in China: Infodemiology Study (Preprint)

2018 ◽  
Author(s):  
Chenjie Xu ◽  
Yi Wang ◽  
Hongxi Yang ◽  
Jie Hou ◽  
Li Sun ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Hodgkin Lymphoma ◽  
Cancer Incidence ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Cointegration Analysis ◽  
Related Information ◽  
Incidence And Mortality ◽  
Search Behaviors ◽  
Search Index

BACKGROUND Cancer poses a serious threat to the health of Chinese people, resulting in a major challenge for public health work. Today, people can obtain relevant information from not only medical workers in hospitals, but also the internet in any place in real-time. Search behaviors can reflect a population’s awareness of cancer from a completely new perspective, which could be driven by the underlying cancer epidemiology. However, such Web-retrieved data are not yet well validated or understood. OBJECTIVE This study aimed to explore whether a correlation exists between the incidence and mortality of cancers and normalized internet search volumes on the big data platform, Baidu. We also assessed whether the distribution of people who searched for specific types of cancer differed by gender. Finally, we determined whether there were regional disparities among people who searched the Web for cancer-related information. METHODS Standard Boolean operators were used to choose search terms for each type of cancer. Spearman’s correlation analysis was used to explore correlations among monthly search index values for each cancer type and their monthly incidence and mortality rates. We conducted cointegration analysis between search index data and incidence rates to examine whether a stable equilibrium existed between them. We also conducted cointegration analysis between search index data and mortality data. RESULTS The monthly Baidu index was significantly correlated with cancer incidence rates for 26 of 28 cancers in China (lung cancer: r=.80, P<.001; liver cancer: r=.28, P=.016; stomach cancer: r=.50, P<.001; esophageal cancer: r=.50, P<.001; colorectal cancer: r=.81, P<.001; pancreatic cancer: r=.86, P<.001; breast cancer: r=.56, P<.001; brain and nervous system cancer: r=.63, P<.001; leukemia: r=.75, P<.001; Non-Hodgkin lymphoma: r=.88, P<.001; Hodgkin lymphoma: r=.91, P<.001; cervical cancer: r=.64, P<.001; prostate cancer: r=.67, P<.001; bladder cancer: r=.62, P<.001; gallbladder and biliary tract cancer: r=.88, P<.001; lip and oral cavity cancer: r=.88, P<.001; ovarian cancer: r=.58, P<.001; larynx cancer: r=.82, P<.001; kidney cancer: r=.73, P<.001; squamous cell carcinoma: r=.94, P<.001; multiple myeloma: r=.84, P<.001; thyroid cancer: r=.77, P<.001; malignant skin melanoma: r=.55, P<.001; mesothelioma: r=.79, P<.001; testicular cancer: r=.57, P<.001; basal cell carcinoma: r=.83, P<.001). The monthly Baidu index was significantly correlated with cancer mortality rates for 24 of 27 cancers. In terms of the whole population, the number of women who searched for cancer-related information has slowly risen over time. People aged 30-39 years were most likely to use search engines to retrieve cancer-related knowledge. East China had the highest Web search volumes for cancer. CONCLUSIONS Search behaviors indeed reflect public awareness of cancer from a different angle. Research on internet search behaviors could present an innovative and timely way to monitor and estimate cancer incidence and mortality rates, especially for cancers not included in national registries.

scholarly journals CANCER INCIDENCE AND MORTALITY IN CHILDREN AND ADOLESCENTS IN PRIMORSKY KRAI FOR THE 2008–2018 PERIOD

2020 ◽  
Vol 19 (6) ◽  
pp. 19-27
Author(s):  
L. M. Minkina ◽  
M. M. Tsvetkov ◽  
Ya. S. Tikhonova ◽  
M. A. Postoykina
Keyword(s):  
Children And Adolescents ◽  
Incidence Rate ◽  
Cancer Incidence ◽  
Cancer Registries ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Annual Growth Rate ◽  
Primorsky Krai ◽  
Incidence And Mortality ◽  
Cancer Incidence Rates

Background. Cancer is a leading cause of death in children and adolescents worldwide. The cancer incidence rate in children and adolescents has been on the rise for decades. Climatic, geographic and social factors of the region play an important role for cancer incidence.Objective: to analyze the cancer incidence and mortality rates in children and adolescents of Prymorsky krai.Methods. Cancer incidence rates in Russia for 2008–2018 as well as cancer incidence among children treated at the regional pediatric hematology/oncology center (Vladivostok, Russia) for 2014–2019 were analyzed.Results. No statistically significant differences in the cancer incidence rates for the 2008–2018 period between children and adolescents of Primorsky krai and the russian federation in the whole and the far-eastern federal district were found. In in Primorsky krai, there was a variability in the incidence rate during the analyzed period, a negative average annual growth rate in the group of children under 14 years of age (-0.86 %). For the 2008–2018 period, the cancer mortality rate in children and adolescents of Primorsky krai significantly decreased (from 5.65 ‰ in 2008 to 2.6 ‰ in 2018), with the average annual increase rate in children aged 017 years of -9.17 %. In 2014–2019, the quality of cancer detection improved significantly, and the number of children and adolescents with stage iiiiv cancer reduced.Conclusion. Cancer prevention and early detection can potentially reduce the cancer incidence and mortality rates in children and adolescents in Primorsky krai. Population-based cancer registries are needed for quantifying the burden of cancer in children and adolescents and assessing prevention and control programs.

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