scholarly journals Biological Tissue Damage Monitoring Method Based on IMWPE and PNN during HIFU Treatment

Information ◽  
2021 ◽  
Vol 12 (10) ◽  
pp. 404
Author(s):  
Bei Liu ◽  
Xian Zhang ◽  
Xiao Zou ◽  
Jing Cao ◽  
Ziqi Peng

Biological tissue damage monitoring is an indispensable part of high-intensity focused ultrasound (HIFU) treatment. As a nonlinear method, multi-scale permutation entropy (MPE) is widely used in the monitoring of biological tissue. However, the traditional MPE method neglects the amplitude information when calculating the time series complexity, and the stability of MPE is poor due to the defects in the coarse-grained process. In order to solve the above problems, the method of improved coarse-grained multi-scale weighted permutation entropy (IMWPE) is proposed in this paper. Compared with the MPE, the IMWPE method not only includes the amplitude of signal when calculating the signal complexity, but also improves the stability of entropy value. The IMWPE method is applied to the HIFU echo signals during HIFU treatment, and the probabilistic neural network (PNN) is used for monitoring the biological tissue damage. The results show that compared with multi-scale sample entropy (MSE)-PNN and MPE-PNN methods, the proposed IMWPE-PNN method can correctly identify all the normal tissues, and can more effectively identify damaged tissues and denatured tissues. The recognition rate for the three kinds of biological tissues is higher, up to 96.7%. This means that the IMWPE-PNN method can better monitor the status of biological tissue damage during HIFU treatment.

Entropy ◽  
2020 ◽  
Vol 22 (9) ◽  
pp. 944
Author(s):  
Bei Liu ◽  
Runmin Wang ◽  
Ziqi Peng ◽  
Lingjie Qin

Identification of denatured biological tissue is crucial to high-intensity focused ultrasound (HIFU) treatment, which can monitor HIFU treatment and improve treatment efficiency. In this paper, a novel method based on compressed sensing (CS) and improved multiscale dispersion entropy (IMDE) is proposed to evaluate the complexity of ultrasonic scattered echo signals during HIFU treatment. In the analysis of CS, the method of orthogonal matching pursuit (OMP) is employed to reconstruct the denoised signal. CS-OMP can denoise the ultrasonic scattered echo signal effectively. Comparing with traditional multiscale dispersion entropy (MDE), IMDE improves the coarse-grained process in the multiscale analysis, which improves the stability of MDE. In the analysis of simulated signals, the entropy value of the IMDE method has less fluctuation compared with MDE, indicating that the IMDE method has better stability. In addition, MDE and IMDE are applied to the 300 cases of ultrasonic scattered echo signals after denoising (including 150 cases of normal tissues and 150 cases of denatured tissues). The experimental results show that the MDE and IMDE values of denatured tissues are higher than normal tissues. Both the MDE and IMDE method can be used to identify whether biological tissue is denatured. However, the multiscale entropy curve of IMDE is smoother and more stable than MDE. The interclass distance of IMDE is greater than MDE, and the intraclass distance of IMDE is less than MDE at different scale factors. This indicates that IMDE can better distinguish normal tissues and denatured tissues to obtain more accurate clinical diagnosis during HIFU treatment.


Entropy ◽  
2019 ◽  
Vol 21 (7) ◽  
pp. 666 ◽  
Author(s):  
Bei Liu ◽  
Shengyou Qian ◽  
Weipeng Hu

Identification of denatured biological tissue is crucial to high intensity focused ultrasound (HIFU) treatment. It is not easy for intercepting ultrasonic scattered echo signals from HIFU treatment region. Therefore, this paper employed time-frequency entropy based on generalized S-transform (GST) to intercept ultrasonic echo signals. First, the time-frequency spectra of ultrasonic echo signal is obtained by GST, which is concentrated around the real instantaneous frequency of the signal. Then the time-frequency entropy is calculated based on time-frequency spectra. The experimental results indicate that the time-frequency entropy of ultrasonic echo signal will be abnormally high when ultrasonic signal travels across the boundary between normal region and treatment region in tissues. Ultrasonic scattered echo signals from treatment region can be intercepted by time-frequency entropy. In addition, the refined composite multi-scale weighted permutation entropy (RCMWPE) is proposed to evaluate the complexity of nonlinear time series. Comparing with multi-scale permutation entropy (MPE) and multi-scale weighted permutation entropy (MWPE), RCMWPE not only measures complexity of signal including amplitude information, but also improves the stability and reliability of multi-scale entropy. The RCMWPE and MPE are applied to 300 cases of actual ultrasonic scattered echo signals (including 150 cases in normal status and 150 cases in denatured status). It is found that the RCMWPE and MPE values of denatured tissues are higher than those of the normal tissues. Both RCMWPE and MPE can be used to distinguish normal tissues and denatured tissues. However, there are fewer feature points in the overlap region between RCMWPE of denatured tissues and normal tissues compared with MPE. The intra-class distance and the inter-class distance of RCMWPE are less and greater respectively than MPE. The difference between denatured tissues and normal tissues is more obvious when RCMWPE is used as the characteristic parameter. The results of this study will be helpful to guide doctors to obtain more accurate assessment of treatment effect during HIFU treatment.


2021 ◽  
Vol 19 (1) ◽  
pp. 102-114
Author(s):  
Bei Liu ◽  
◽  
Wenbin Tan ◽  
Xian Zhang ◽  
Ziqi Peng ◽  
...  

<abstract> <p>The recognition of denatured biological tissue is an indispensable part in the process of high intensity focused ultrasound treatment. As a nonlinear method, multi-scale permutation entropy (MPE) is widely used in the recognition of denatured biological tissue. However, the traditional MPE method neglects the amplitude information when calculating the time series complexity. The disadvantage will affect the recognition effect of denatured tissues. In order to solve the above problems, the method of multi-scale rescaled range permutation entropy (MRRPE) is proposed in this paper. The simulation results show that the MRRPE not only includes the amplitude information of the signal when calculating the signal complexity, but also extracts the extreme volatility characteristics of the signal effectively. The proposed method is applied to the HIFU echo signals during HIFU treatment, and the support vector machine (SVM) is used for recognition. The results show that compared with MPE and the multi-scale weighted permutation entropy (MWPE), the recognition rate of denatured biological tissue based on the MRRPE is higher, up to 96.57%, which can better recognize the non-denatured biological tissues and the denatured biological tissues.</p> </abstract>


Entropy ◽  
2019 ◽  
Vol 21 (6) ◽  
pp. 621 ◽  
Author(s):  
Zhilin Dong ◽  
Jinde Zheng ◽  
Siqi Huang ◽  
Haiyang Pan ◽  
Qingyun Liu

Multi-scale permutation entropy (MPE) is an effective nonlinear dynamic approach for complexity measurement of time series and it has been widely applied to fault feature representation of rolling bearing. However, the coarse-grained time series in MPE becomes shorter and shorter with the increase of the scale factor, which causes an imprecise estimation of permutation entropy. In addition, the different amplitudes of the same patterns are not considered by the permutation entropy used in MPE. To solve these issues, the time-shift multi-scale weighted permutation entropy (TSMWPE) approach is proposed in this paper. The inadequate process of coarse-grained time series in MPE was optimized by using a time shift time series and the process of probability calculation that cannot fully consider the symbol mode is solved by introducing a weighting operation. The parameter selections of TSMWPE were studied by analyzing two different noise signals. The stability and robustness were also studied by comparing TSMWPE with TSMPE and MPE. Based on the advantages of TSMWPE, an intelligent fault diagnosis method for rolling bearing is proposed by combining it with gray wolf optimized support vector machine for fault classification. The proposed fault diagnostic method was applied to two cases of experimental data analysis of rolling bearing and the results show that it can diagnose the fault category and severity of rolling bearing accurately and the corresponding recognition rate is higher than the rate provided by the existing comparison methods.


IEEE Access ◽  
2021 ◽  
pp. 1-1
Author(s):  
Yiting Li ◽  
Haisong Huang ◽  
Qipeng Chen ◽  
Qingsong Fan ◽  
Huafeng Quan

Information ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 278
Author(s):  
Sanlong Jiang ◽  
Shaobo Li ◽  
Qiang Bai ◽  
Jing Yang ◽  
Yanming Miao ◽  
...  

A reasonable grasping strategy is a prerequisite for the successful grasping of a target, and it is also a basic condition for the wide application of robots. Presently, mainstream grippers on the market are divided into two-finger grippers and three-finger grippers. According to human grasping experience, the stability of three-finger grippers is much better than that of two-finger grippers. Therefore, this paper’s focus is on the three-finger grasping strategy generation method based on the DeepLab V3+ algorithm. DeepLab V3+ uses the atrous convolution kernel and the atrous spatial pyramid pooling (ASPP) architecture based on atrous convolution. The atrous convolution kernel can adjust the field-of-view of the filter layer by changing the convolution rate. In addition, ASPP can effectively capture multi-scale information, based on the parallel connection of multiple convolution rates of atrous convolutional layers, so that the model performs better on multi-scale objects. The article innovatively uses the DeepLab V3+ algorithm to generate the grasp strategy of a target and optimizes the atrous convolution parameter values of ASPP. This study used the Cornell Grasp dataset to train and verify the model. At the same time, a smaller and more complex dataset of 60 was produced according to the actual situation. Upon testing, good experimental results were obtained.


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