scholarly journals Prognostic Value of Cardiac Troponin and Risk Assessment in Pediatric Supraventricular Tachycardia

2021 ◽  
Vol 10 (16) ◽  
pp. 3638
Author(s):  
Chieh-Ching Yen ◽  
Shou-Yen Chen ◽  
Chung-Hsien Chaou ◽  
Chih-Kai Wang ◽  
Hsin-Tzu Yeh ◽  
...  
Keyword(s):  
Supraventricular Tachycardia ◽  
Cardiac Troponin ◽  
Prognostic Value ◽  
Pediatric Patients ◽  
Troponin I ◽  
Multivariable Logistic Regression Analysis ◽  
Cardiac Events ◽  
Positive Group ◽  
Gastrointestinal Discomfort ◽  
Significant Difference

Cardiac troponin I (cTnI) elevation is common in an acute episode of supraventricular tachycardia (SVT). However, there is limited evidence regarding the prognostic value of cTnI and the predictors of SVT recurrence in pediatric patients. We screened the electronic medical records of all pediatric patients presenting to the emergency departments at five Taiwanese hospitals from 1 January 2010 to 31 May 2021. Our primary outcomes were the occurrence of major adverse cardiac events (MACEs) during the follow-up period and 30-day SVT recurrence. A total of 112 patients were included in our study. Of these, 29 (25.9%) patients had positive cTnI values. Patients with cTnI elevation had significantly more complaints of dyspnea (27.6% vs. 7.2%, p = 0.008) and gastrointestinal discomfort (24.1% vs. 4.8%, p = 0.006). There were significantly more intensive care unit admissions (41.4% vs. 16.9%, p = 0.007) among the cTnI-positive group. One MACE was found in the cTnI-negative group. For 30-day SVT recurrence, the cTnI-positive group had a higher recurrence rate, without a statistically significant difference (20.7% vs. 7.2%, p = 0.075). Multivariable logistic regression analysis showed hypotension as an independent predictor of 30-day SVT recurrence (OR = 4.98; Cl 1.02–24.22; p = 0.047). Troponin had low value for predicting the outcomes of pediatric patients with SVT. The only significant predictor for recurrent SVT was initial hypotension.

Cardiac anthracycline risk: Prognostic value of troponin I (TnI) and B-natriuretic peptide (BNP)

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e20726-e20726
Author(s):  
A. S. Bertolini ◽  
A. Croce ◽  
O. Fusco ◽  
E. Berardi ◽  
F. Malugani ◽  
...  
Keyword(s):  
Prognostic Value ◽  
Troponin I ◽  
Strong Predictor ◽  
High Dose Chemotherapy ◽  
Left Ventricular ◽  
High Dose ◽  
Cardiac Events ◽  
Patients With Cancer ◽  
Time Period ◽  
Significant Difference

e20726 Background: In patients with cancer who are undergoing to high-dose chemotherapy (HDC), even minimal elevation of TnI is associated with late left ventricular dysfunction. A TnI increase soon after HDC is a strong predictor of poor cardiological outcome. BNP elevation seems to have same prognostic value. Patients treated by standard Anthracycline-based chemotherapy (ADM-CT) doses could not have benefit from TnI/BNP evaluation; on the contrary the method could adsorb too much resources and may not be rational. Methods: To evaluate cardio toxicity trend we studied TnI and BNP in plasma samples of 28 breast cancer pts (female, adjuvant setting, mean age 50), treated with ADM-CT. The samples were detected before (a) one hour (b) and ten days (c) after each course. TnI was considered positive for values ≥ 0.044 ng/mL; BNP for values ≥ 100pg/mL .Comparison between TnI and BNP values were made with the ANOVA method. A probability value < 0.05 was considered statistically significant. Each patient was followed also with LVEF (basal & 3 months after). Results: At present we observed 135 events, mean TnI: (a) 0,00672, (b) 0,006512, (c) 0,005791; BNP (a) 33.8, (b) 36.4, (c) 35.2. We performed 405 detections for both tests; costs: 8.707$ BNP, 10.327$ TnI. No significant difference in test values has been observed between the different time periods. We can't indicate a trend referring to therapy or a particular time period. No patients had LVEF variation. Conclusions: TnI and BNP release pattern after ADM-CT doesn't identify patients at different risk of cardiac events. The program appears useful for HDC treatments, while in normal chemotherapy the data are ongoing and expensive. No significant financial relationships to disclose.

scholarly journals Postoperative Cardiac Troponin I (cTnI) Level and Its Prognostic Value for Patients Undergoing Mitral Valve Surgery

2010 ◽  
Vol 51 (3) ◽  
pp. 166-169 ◽  
Author(s):  
Kiyohiro Oshima ◽  
Fumio Kunimoto ◽  
Toru Takahashi ◽  
Jun Mohara ◽  
Izumi Takeyoshi ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Cardiac Troponin ◽  
Prognostic Value ◽  
Troponin I ◽  
Mitral Valve Surgery ◽  
Valve Surgery ◽  
Cardiac Troponin I ◽  
Ctni Level

Prognostic Value of Cardiac Troponin I In Infective Endocarditis

2021 ◽  
Vol 23 (Supplement_D) ◽  
Author(s):  
Salma M Thabet ◽  
Marwa Meshaal ◽  
Yasser Yazied ◽  
Yasser Sharaf
Keyword(s):  
Heart Failure ◽  
Infective Endocarditis ◽  
Cardiac Troponin ◽  
Prognostic Value ◽  
Troponin I ◽  
Cardiac Troponin I ◽  
P Value ◽  
Significant Relation ◽  
P Values ◽  
Septic Pulmonary Embolism

Abstract Aim The aim of this study is to assess the prognostic value of cardiac troponin I as a predictor of in-hospital morbidity and mortality in patients with infective endocarditis. Methods This study included 48 patients with definite and possible IE according to modified Duke’s criteria for diagnosis of IE. This prospective longitudinal study was conducted on patients admitted to the cardiovascular department of Cairo University hospitals. All patients were subjected to full history taking and clinical examination, all laboratory and radiological investigations which included chest radiography, echocardiogram and other diagnostic procedures as needed for diagnosis and follow-up of IE were done with emphasis on cardiac troponin I level on admission. Results Troponin I was found to be statistically significant predictor for heart failure (NYHA III/IV), septic pulmonary embolism and in-hospital mortality in infective endocarditis patients by univariate and multivariate regression analysis with P values 0.023, 0.037and 0.002 respectively. Tricuspid valve vegetations had showed significant relation to troponin I levels with p value 0.033. Also it was found that SOFA score on first day of admission showed significant relation to troponin I level with P value 0.045 and 0.004 for prediction of hospital stay duration. Shock and intracranial hemorrhage showed borderline significance with P values 0.097, 0.069. On other hand, troponin I as predictor of pulmonary edema, mechanical complications, systemic embolization, acute kidney injury and presence of aortic root abscess had no statistical significance in our studied patients. Conclusions This study showed that there is as significant predictive value of elevated cardiac troponin I with heart failure, septic pulmonary embolism and all cause in-hospital mortality. In addition, it was significant predictor of the length of hospital stay, lymphocytosis and SOFA score. These results are emphasizing that cTn I level may predict higher risk patients who would need early and aggressive control of infection medically alone or combined with surgery in IE patients.

Prognostic Value of Troponin I with Echocardiography Assessment in Septic Patients

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Sherif Farouk Ibrahim ◽  
Ashraf Elsayed Elagmy ◽  
Abdelrhman Gamal Abdelsabour
Keyword(s):  
Septic Shock ◽  
Acute Coronary Syndrome ◽  
Intensive Care ◽  
Cardiac Troponin ◽  
Prognostic Value ◽  
Troponin I ◽  
Cardiac Troponin I ◽  
Coronary Syndrome ◽  
Sepsis And Septic Shock

Abstract Background Sepsis is heterogenous with regard to factors such as causal microorganism, patient predisposition, co-morbidity and response to therapy, a key element and unifying feature is the manifestation of cardiovascular dysfunction. Elevated concentrations of cardiac troponin I (cTnI) are frequently observed in patients with severe sepsis and septic shock even in the absence of an acute coronary syndrome (ACS). Objective To evaluate the prognostic value of (cTnI) with echocardiography assessment in septic patients. Patients and Methods This study was conducted at the intensive care units of Ain Shams university hospitals. 20 patients of both sexes with age ranging from 18 to 70 years diagnosed with sepsis admitted to Intensive care unit were included in prospective observational study. Results Baseline cTnI had a significant positive correlation with follow up troponine (p = 0.0016). Baseline EF had a significant negative correlation with follow up troponine (p = 0.036). Using ROC-curve analysis, troponin level at a cutoff point (&gt;1.9) predicted patients with mortality, with good (87%) accuracy, sensitivity= 90% and specificity= 90% (p &lt; 0.01). Conclusion Elevated concentrations of cardiac troponin I (cTnI) are frequently observed in patients with sepsis and septic shock even in the absence of an acute coronary syndrome.

Prognostic value of high-sensitive cardiac troponin I in asymptomatic chronic hemodialysis patients

2019 ◽  
Vol 33 (1) ◽  
pp. 129-136
Author(s):  
Barbara Maresca ◽  
Andrea Manzione ◽  
Alessandra Moioli ◽  
Gerardo Salerno ◽  
Patrizia Cardelli ◽  
...  
Keyword(s):  
Cardiac Troponin ◽  
Prognostic Value ◽  
Troponin I ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Cardiac Troponin I

scholarly journals Prognostic value of elevated cardiac troponin I in patients with intracerebral hemorrhage

2019 ◽  
Vol 43 (4) ◽  
pp. 338-345
Author(s):  
Yangchun He ◽  
Qigong Liu ◽  
Jing Wang ◽  
Dao Wen Wang ◽  
Hu Ding ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Cardiac Troponin ◽  
Prognostic Value ◽  
Troponin I ◽  
Cardiac Troponin I

scholarly journals The correlation of 30- and 90-day mortality rates with Hs-troponin I values measured in patients diagnosed with paroxysmal supraventricular tachycardia in emergency service

2019 ◽  
pp. 102490791987142
Author(s):  
Erdem Kurt ◽  
Rohat AK ◽  
Şebnem Zeynep Eke Kurt ◽  
Suphi Bahadırlı ◽  
Tuba Cimilli Öztürk
Keyword(s):  
Supraventricular Tachycardia ◽  
Large Scale ◽  
Emergency Service ◽  
Troponin I ◽  
International Classification Of Diseases ◽  
Mortality Rates ◽  
Paroxysmal Supraventricular Tachycardia ◽  
Significant Difference ◽  
Classification Of Diseases ◽  
Artery Disease

Background: This study aims to determine the relationship between troponin levels and 30- and 90-day mortality rates in patients who applied to emergency service with paroxysmal supraventricular tachycardia. Materials and methods: The data of our study were obtained from the retrospective screening of the files of 321 patients who applied to the emergency department between 1 January 2015 and 31 December 2016 with International Classification of Diseases diagnosis with I47.1 (supraventricular tachycardia). Unstable patients, patients under 18 years, and patients with comorbidities that could increase troponin levels did not participate in the study. A total of 159 patients diagnosed with paroxysmal supraventricular tachycardia were included in the study. These patients’ files were examined, and their examination and anamnesis information at the time of admission to hospital, demographic characteristics, and applied treatments were analyzed. The 30- and 90-day mortality rates of the patients were examined. Results: The study was carried out with 159 patients. Troponin was positive in 25 (15.7%) cases, while it was negative in 134 (84.3%) cases. There was no significant difference between the two groups in terms of 30- and 90-day mortality rates. Coronary artery disease was found to be higher in patients with positive troponin than patients with negative troponin. Conclusion: No significant difference was found between patients with positive troponin values compared to patients with negative troponin values in terms of 30- and 90-day mortality rates. We believe that prospective observational studies or large-scale retrospective studies will better elucidate this issue.

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