scholarly journals Following Pediatric and Adult IBD Patients through the COVID-19 Pandemic: Changes in Psychosocial Burden and Perception of Infection Risk and Harm over Time

2021 ◽  
Vol 10 (18) ◽  
pp. 4124
Author(s):  
Leandra Koletzko ◽  
Elisabeth Klucker ◽  
Thu Giang Le Thi ◽  
Simone Breiteneicher ◽  
Raquel Rubio-Acero ◽  
...  

Background: COVID-19-associated restrictions impact societies. We investigated the impact in a large cohort of inflammatory bowel disease (IBD) patients. Methods: Pediatric (pIBD) and adult patients and pIBD parents completed validated questionnaires for self-perceived stress (Perceived Stress Questionnaire, PSQ) and quality of life from July to October 2020 (1st survey) and March to April 2021 (2nd survey). Analyses were stratified by age groups (6–20, >20–40, >40–60, >60 years). Perceived risk of infection and harm from COVID-19 were rated on a 1–7 scale. An index for severe outcome (SIRSCO) was calculated. Multivariable logistic regression analysis was performed. Results: Of 820 invited patients, 504 (62%, 6–85 years) patients and 86 pIBD parents completed the 1st, thereof 403 (80.4%) the 2nd survey. COVID-19 restrictions resulted in cancelled doctoral appointments (26.7%), decreased physical activity, increased food intake, unintended weight gain and sleep disturbance. PSQ increased with disease activity. Elderly males rated lower compared to females or younger adults. PSQ in pIBD mothers were comparable to moderate/severe IBD adults. Infection risk and harm were perceived high in 36% and 75.4%. Multivariable logistic models revealed associations of higher perceived risk with >3 household members, job conditions and female gender, and of perceived harm with higher SIRSCO, unintended weight change, but not with gender or age. Cancelled clinic-visits were associated with both. SARS-CoV-2 antibodies prior 2nd infection wave were positive in 2/472 (0.4%). Conclusions: IBD patients report a high degree of stress and self-perceived risk of complications from COVID-19 with major differences related to gender and age. Low seroprevalence may indicate altered immune response.

2021 ◽  
Vol 12 ◽  
Author(s):  
Greta Castellini ◽  
Lorenzo Palamenghi ◽  
Mariarosaria Savarese ◽  
Serena Barello ◽  
Salvatore Leone ◽  
...  

Objective: This study aimed to evaluate the impact of the COVID-19 emergency on patients with IBD's psychological distress, understanding the role of patient engagement as a mediator.Methods: An online questionnaire was created, measuring perceived risk susceptibility toward COVID-19, perceived stress, and patient engagement. The questionnaire was distributed to a purposive sample of IBD patients who belonged to the Italian Association for patients with IBD (AMICI Onlus) in April 2020. Structural equation models were implemented.Results: The effect of the perceived risk susceptibility toward COVID-19 contagion on the perceived stress is fully mediated by patient engagement (β = 0.306, p < 0.001). Moreover, the patient engagement mitigates the perceived stress (β = −0.748, p < 0.001) in our sample of IBD patients, and it is negatively influenced by the perceived risk susceptibility toward COVID-19 (β = −0.410, p < 0.001).Conclusion: Patient engagement is the key factor that explains how the perceived risk susceptibility toward COVID-19 affects the perceived psychological distress in patients with IBD, underlining that the perceived risk of contagion increases their perceived level of stress through a decrease of patient engagement.


2005 ◽  
Vol 27 (2) ◽  
pp. 119-123 ◽  
Author(s):  
Clarissa Marceli Trentini ◽  
Flávio Merino de Freitas Xavier ◽  
Eduardo Chachamovich ◽  
Neusa Sica da Rocha ◽  
Vânia N Hirakata ◽  
...  

BACKGROUND: The Beck Depression Inventory (BDI) has been widely used to assess the prevalence of depressive symptomatology in clinical and non-clinical samples. On elders, however, the Beck Depression Inventory total score can be influenced by the increased scores on somatic and performance subscale due to the impact of ageing process itself and clinical diseases. PURPOSE: To verify if there are differences between answers of adults and elders for the BDI Somatic and Performance subscale. METHODS: Five hundred and fifty six subjects were interviewed. Two hundred and seventeen were adults (between 18 and 59 years old) and 339 were elders (> 60 years). Adults and elders with terminal diseases or dementia were excluded. The convenience sampling method was used. RESULTS: Elders answered significantly with higher scores in the Somatic and Performance subscale compared to adults (p < 0.001). Female gender and educational level were also associated to higher scores in the Somatic subscale. No differences between both age groups were found in the Cognitive-Affective subscale (p = 0.332). CONCLUSIONS: Positive answers in the BDI Somatic and Performance subscale must be carefully assessed among elder subjects. The age factor, either by aging or due to several diseases, can bring signs that are not necessarily symptoms of major depression. Further studies are suggested.


Angiology ◽  
2020 ◽  
pp. 000331972096194
Author(s):  
Kuljit Singh ◽  
Rosanna Tavella ◽  
Tracy Air ◽  
Matthew Worthley ◽  
Ajay Sinhal ◽  
...  

The differential impact of young age and female gender on transradial access (TRA) outcomes remains to be confirmed. The primary objective was to assess the impact of young age and female gender on in-hospital net adverse cardiovascular events (NACE). Among 12 346 patients from the Coronary Angiogram Database of South Australia (CADOSA) Registry, the impact of gender; men (transfemoral access [TFA] 1995, TRA 6168) and women (TFA 1249, TRA 2934), and a median split of age, ≤63 years (TFA 1617, TRA 4727) and >63 years (TFA 1627, TRA 4375) were analyzed on in-hospital outcomes by creating 5 separate propensity-matched cohorts (entire cohort, men, women, ≤63 and > 63 years). Net adverse cardiovascular event reduction with TRA was limited to the >63 years old cohort (odds ratio [OR] = 0.56, 95% CI: 0.34-0.93, P = .02) and women (OR = 0.37, 95% CI: 0.18-0.76, P = .007). In both the age groups and genders, TRA was associated with a lower risk of bleeding and all-cause mortality. On multivariate logistic regression, TRA was associated with a significant reduction in NACE, major bleeding, and mortality in the overall cohort. In conclusion, a reduction in bleeding and mortality was noted with TRA in all the subgroups in this observational study.


Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Yoshihide Mitani ◽  
Noriko Yodoya ◽  
Hiroyuki Ohashi ◽  
Hirofumi Sawada ◽  
Masahiro Hirayama

Introduction: Out-of-hospital cardiac arrests (OHCA) of presumed cardiac origin witnessed by nonfamily members in the daytime are most effectively resuscitated in the youth, in which the impact of recently disseminated hands-only cardiopulmonary resuscitation (CPR) is poorly understood. Hypothesis: Dissemination of hands-only CPR is associated with the better outcome in school students and young adults after such OHCA. Methods: We investigated OHCA of presumed cardiac origin in the youth (Group A, 7-12y; group B, 13-18y; group C, 19-22y; group D, 23-35y) which are witnessed by nonfamily members in the daytime (6:00-17:59) during 2005-15 by using Japanese nationwide Utstein registry. Results: We recruited 1,646 pts, in which N of pts was 92 (A), 382 (B), 229 (C) and 943 (D); ventricular fibrillation (VF) as the initial rhythm (%) was 48, 70, 64, and 59; bystander’s CPR (%) was 81, 80, 71 and 68; hands-only/bystander’s CPR (%) was 32, 38, 57, 56; bystander’s automated external defibrillator (AED) (%) was 37, 44, 24 and 19; the favorable neurological outcome at 1 month (CPC1-2)(%) was 46, 49, 39 and 30. Compared with group D, %bystander’s CPR (p=.013 in A, <.001 in B), %bystander’s AED (<.001 in both), and %CPC1-2 (.005, <.001) was higher but %hands-only CPR(<.001 in both) was lower in A and B, independent of the calendar year. Compared with 2005-09, %hands-only CPR, %bystander’s AED and CPC1-2 were higher in all age groups (<.005 in all) in 2010-15. In multivariate logistic analysis (gender, age groups (vs D), CPR type (conventional or hands-only CPR vs no CPR), bystander’s AED, the initial VF, emergency response time, calendar year), hands-only CPR (p=.03), bystander’s AED(<.001), female gender(.045), initial VF (<.001), emergency response time (<.001), and calendar year (<.001) were independently associated with CPC1-2. Conclusions: The present investigation demonstrates that resuscitation and outcome parameters after OHCA of presumed cardiac origin were persistently better in school students than young adults and that %hands-only CPR, which was persistently lower in school students, was independently associated with the better outcome in the youth overall. This finding may give a clue to further improvement of the outcomes in school students after OHCA.


Medicina ◽  
2019 ◽  
Vol 55 (3) ◽  
pp. 75 ◽  
Author(s):  
Jurgita Gailite ◽  
Dana Apela ◽  
Iveta Dzīvīte-Krišāne ◽  
Dace Gardovska

Background and objectives: The efficacy of a weight correction programme can be affected by such predictors as the number of contact hours, gender, age, baseline weight, parental weight status, psycho-emotional status, insulin resistance, and socioeconomic status. The aim of this current study was to evaluate the overall efficacy of the Weight Correction Programme at Children’s Clinical University Hospital, and explore the impact of the probable predictors. We evaluated the efficacy depending on gender, age, parental weight status, signs of depression, baseline body mass index z-score (z-BMI), and baseline waist circumference. Materials and Methods: The data were gathered from medical records. The inclusion criteria were as follows: Entered the programme by 13 June 2017, at least five years old, follow-up data available. All the respondents were divided into two age groups: <10 years old and ≥10 years old. Results: The study included 181 respondents. They were 5 to 17 years old on the first day of participation in the Weight Correction Programme. Results indicated that 117 (65%) patients managed to reduce z-BMI and 69 (38%) patients achieved clinically significant reduction of z-BMI. Boys had four times higher odds (odds ratio (OR) = 4,22; CI 1.37–13.05; p = 0.012) to reduce their z-BMI by at least 0.20 units than girls. The respondents of the older age group (≥10 years) had a better chance to reduce z-BMI than the younger ones (OR = 11,51; CI 2.04–64.83; p = 0.006). The odds to reduce z-BMI were lower by 7% for every extra cm of waist circumference (OR = 0.93; CI 0.88–0.99; p = 0.014) for reducing z-BMI. The follow-up time was also a positive predictor, and with every month the odds for clinically significant z-BMI reduction increased by 7% (OR = 1.07; CI 1.00–1.15; p = 0.047). The parental weight status, signs of depression, and baseline z-BMI were not significant predictors. Conclusions: More than half of the patients of the respondents managed to reduce their z-BMI. Female gender, younger age, and larger waist circumference were negative predictors.


2022 ◽  
Vol 30 (3) ◽  
pp. 1-13
Author(s):  
Yi Sun ◽  
Yunrong Li

Cross-border e-commerce(CBRC) is increasingly affecting the value of traditional trade due to its rich variety, convenient operation, and free of time and space restrictions, and has also changed the consumer's Shopping habits. However, the development of CBEC still faces many problems, resulting in domestic consumers' willingness to consume on CBEC platforms is not high. Based on the above background, the research content of this paper is the influence of consumer trust on purchase intention based on perceived risk of CBEC platforms. In this paper, a questionnaire survey is used to collect data for simulation. The results show that from the regression results of the five dimensions of trust on purchase intention, the adjusted R2 is 0.466, indicating a high degree of fit. When the exploratory value in perceived promotional gains is high, it will leave consumers in an irrational state and weaken the perception of risk.


Author(s):  
Antonio Fontes Lima ◽  
Filipa Carvalho Moreira ◽  
Isabel Esteves Costa ◽  
Catia Azevedo ◽  
Fernando Mar ◽  
...  

Abstract Introduction Tinnitus is experienced by a significant part of the patients suffering from otosclerosis. Objective To assess the prevalence of tinnitus in otosclerosis, its main features, and the impact on the daily life. Methods Patients diagnosed with otosclerosis in 2019 in a tertiary hospital were enrolled in the study. Demographic data were retrieved and, besides a regular audiometric evaluation, the patients underwent acuphenometry to assess the psychoacoustic measurements (pitch and loudness), and the Tinnitus Handicap Inventory (THI). Results In total, 66 patients fulfilled the inclusion criteria, with a female predominance (63.6%; n = 42), and a mean age of 48.7 years. The mean air-bone gap was of 26.3 dB. A total of 72.7% complained of tinnitus; it was mostly unilateral, identified in the low frequencies, namely 500 Hz, with median loudness of 7.5 dB. The median score on the THI score was of 37; most patients had a mild handicap (33.3%, n = 16), followed by those with a severe handicap (22.9%; n = 11). The female gender had a statistically significant association with the presence of tinnitus. The THI scores were higher in middle-aged patients (age groups: 40 to 49 and 50 to 59 years), which was statistically significant. No correlation was found between audiometry results and the prevalence of tinnitus or score on the THI. On the other hand, high-pitched tinnitus, compared to low pitched-tinnitus, was associated with larger air-bone gaps. Conclusion The prevalence of tinnitus in our population was in line with the prevalences reported in the literature. It caused a catastrophic handicap in 22.9% of the patients. High-pitched tinnitus was associated with higher handicap. Nonetheless, the existence of tinnitus and its severity were not associated with the degree of hearing loss.


2021 ◽  
Author(s):  
Manuel Schabus ◽  
Esther-Sevil Eigl

The survey “Now it’s your turn to speak up!” evaluates the psychosocial burden and impairments of children and adolescents in Austria during the ongoing COVID-19 pandemic. Using an online-questionnaire, 5483 children and adolescents between 6 and 18 years shared their feelings, fears, worries and thoughts regarding the coronavirus pandemic. Most of them report a high degree of fear due to the current situation, with especially female participants being under more emotional strain than their male counterparts. Associated to this, the risk of a COVID-19-associated hospitalization is strongly overestimated, as previously found in adults. In addition, an alarming lack of perspective during the ongoing pandemic is evident across all age groups including the youngest participants aged 6-10 years. Feelings of fury, anger, loneliness, and sadness are reported much more frequently than previously. Last but not least, our study shows an alarming reduction of sleep quality and a drastic increase in self-reported sleep problems already in this young population. The results of the “Jetzt Sprichst Du!” survey emphasize the need for immediate action in order to limit the collateral damage caused on the psychosocial, developmental and health dimension as far as this is still possible today.


2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Koichiro Hayashi ◽  
Hiromasa Tsujiguchi ◽  
Daisuke Hori ◽  
Yohei Yamada ◽  
Yukari Shimizu ◽  
...  

Abstract Background Food allergy (FA) is a common disease in children, and its prevalence has increased in developed countries. The impact of overweight on children health also becomes an important social problem. However, the relationship between overweight and FA is still unclear. We examined the association between overweight and the prevalence of FA among Japanese children. Methods We analyzed data obtained using a self-administered questionnaire from 1772 Japanese children. Weight groups according to body mass index cutoff points proposed by the International Obesity Task Force were used to create two groups: overweight and non-overweight. Children were separated into four age groups (3–6 years, 6–9 years, 9–12 years, and 12–15 years) to examine age differences. We performed univariate and multivariate logistic models to examine the association between overweight and FA. Results The prevalence of FA was significantly higher in boys (10.6%, p = 0.014) than girls (4.5%) and girls (7.9%, p = 0.012) than boys (2.5%) for 6–9 and 12–15 age groups, respectively. While the prevalence of FA was significantly higher in overweight than non-overweight girls (26.1%, p = 0.005) in the 12–15 age group, no significant difference was found in boys. In girls, overweight was significantly associated with FA after adjustment for age and asthma (odds ratio 1.99, 95% confidence interval 1.01–3.89, p = 0.046). Conclusions Our results showed that being overweight was significantly associated with a higher prevalence of FA in girls, but not in boys. Further prospective studies are necessary to find the causal relationship between overweight and FA.


2022 ◽  
Vol 30 (3) ◽  
pp. 0-0

Cross-border e-commerce(CBRC) is increasingly affecting the value of traditional trade due to its rich variety, convenient operation, and free of time and space restrictions, and has also changed the consumer's Shopping habits. However, the development of CBEC still faces many problems, resulting in domestic consumers' willingness to consume on CBEC platforms is not high. Based on the above background, the research content of this paper is the influence of consumer trust on purchase intention based on perceived risk of CBEC platforms. In this paper, a questionnaire survey is used to collect data for simulation. The results show that from the regression results of the five dimensions of trust on purchase intention, the adjusted R2 is 0.466, indicating a high degree of fit. When the exploratory value in perceived promotional gains is high, it will leave consumers in an irrational state and weaken the perception of risk.


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