scholarly journals Structure–Function Relationship and Vision-Related Quality of Life in Glaucoma Secondary to Anterior Uveitis: Comparison with Open Angle Glaucoma

2021 ◽  
Vol 10 (18) ◽  
pp. 4231
Author(s):  
Ji-Young Lee ◽  
Jin-Ho Kim ◽  
Tae-Yoon La ◽  
Jin-A Choi
Keyword(s):  
Quality Of Life ◽  
Structure Function ◽  
Open Angle Glaucoma ◽  
Normal Tension Glaucoma ◽  
Composite Score ◽  
Mean Deviation ◽  
Open Angle ◽  
Fiber Layer ◽  
Related Quality

Purpose: The aim of this study is to investigate the structure–function characteristics and vision-related quality of life (VR-QoL) in uveitic glaucoma (UG) compared with open-angle glaucoma (OAG). Method: The study included 69 patients with UG and 138 patients with primary open angle glaucoma, normal-tension glaucoma. A 25-item National Eye Institute Visual Function Questionnaire (VFQ-25) was used to evaluate the patients’ VR-QoL. The retinal nerve fiber layer thickness (RNFLT) was measured using optical coherence tomography, and the integrated visual field (IVF) was determined using the best location method. Results: There were no significant differences in the binocular IVF and mean deviation (MD) of the affected eye between the OAG and UG group, whereas the average RNFLT was significant thinner in the OAG group (p = 0.008). The patients with UG showed a significantly lower composite score and five subscales of the VFQ-25, compared with those with OAG (p < 0.05, for all, general linear model). Multivariate linear regression analyses showed that the composite score showed the strongest associations with the whole IVF (β = 1.240, p < 0.001) in the OAG group, whereas in the UG group, a significant association was seen only with the inferior VF of the affected eye (β = 0.596, p = 0.038). Conclusions: The eyes with UG exhibited distinctive structure–function characteristics and worse VR-QoL that differentiated them from OAG eyes.

scholarly journals Structure–function Relationship and Vision-related Quality of Life in Glaucoma Secondary to Anterior Uveitis: Comparison with Open Angle Glaucoma

2021 ◽  
Author(s):  
Jin A Choi ◽  
Ji-Young Lee ◽  
Tae Yoon La ◽  
Jin-Ho Kim
Keyword(s):  
Quality Of Life ◽  
Structure Function ◽  
Visual Function ◽  
Open Angle Glaucoma ◽  
Composite Score ◽  
Open Angle ◽  
Structure Function Relationship ◽  
Related Quality ◽  
Function Relationship

Abstract Uveitis is the most common inflammatory ocular disorder and frequently complicated by glaucoma, which is an important cause of irreversible sight loss. Inflammatory nature of the disease and widely fluctuating of intraocular pressure may affect visual function in patients with uveitis complicated by glaucoma. Therefore, we investigated the structure − function relationship and vision-related quality of life (VR-QoL) in 69 patients with uveitic glaucoma (UG), compared with 138 patients with primary open-angle glaucoma (OAG) using 25-item National Eye Institute Visual Function Questionnaire (VFQ-25). In a generalized linear model including age and corresponding structural metrics, the UG eyes had significantly lower mean deviation (MD) of the whole visual field (VF) and superior VF than the OAG eyes (p = 0.012 and 0.040). Patients with UG showed significantly lower composite score and 5 subscales of the VFQ-25, compared with those with OAG (p < 0.05, for all). In the OAG group, the composite score showed strongest associations with the whole binocular integrated VF (β = 1.156, p < 0.001), whereas in the UG group, a significant association was seen only with the inferior VF of the affected eye (β = 0.747, p = 0.005). In conclusion, eyes with UG exhibited a distinctive structure–function relationship and worse VR-QoL that differentiated them from OAG eyes.

scholarly journals Impact of socioeconomic status on vision-related quality of life in primary open-angle glaucoma

Eye ◽  
2017 ◽  
Vol 31 (10) ◽  
pp. 1480-1487 ◽  
Author(s):  
Y-S Kuo ◽  
C J-L Liu ◽  
H-C Cheng ◽  
M-J Chen ◽  
W-T Chen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Socioeconomic Status ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Related Quality

scholarly journals Relationship between electronically measured medication adherence and vision-related quality of life in a cohort of patients with open-angle glaucoma

2018 ◽  
Vol 3 (1) ◽  
pp. e000114 ◽  
Author(s):  
Atalie C Thompson ◽  
Sandra Woolson ◽  
Maren K Olsen ◽  
Susanne Danus ◽  
Hayden B Bosworth ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Visual Acuity ◽  
Medication Adherence ◽  
Open Angle Glaucoma ◽  
Mean Difference ◽  
Eye Drops ◽  
Open Angle ◽  
Related Quality ◽  
Adjusted Model

ObjectiveTo investigate whether electronically measured medication adherence is associated with vision-related quality of life (VRQoL) in patients with open-angle glaucoma.Methods and analysisThis is a 3-year prospective cohort study of 79 subjects with open-angle glaucoma at a Veterans Affairs medical centre. Participants returned a medication event monitoring system (MEMS) for their glaucoma eye-drops and had at least two visits with glaucoma during the study period. Those taking less than 80% of prescribed glaucoma medication doses were considered to be non-adherent. Subjects were interviewed using the National Eye Institute’s Visual Function Questionnaire-25 (VFQ-25) at baseline and after 3 years.ResultsThirty per cent (n=24/79) of participants took less than 80% of prescribed doses of their glaucoma medications at baseline. Patients who did not adhere to their medications at baseline had lower mean composite VFQ-25 scores at baseline (70.66±20.50 vs 75.91±19.12, standardised mean difference=0.27) and after 3 years (71.68±21.93 vs 76.25±21.67, standardised mean difference=0.21). Visual acuity (P=0.03), but not visual field severity (P=0.13) or medication adherence (P=0.30), was significantly associated with composite VFQ-25 score in an adjusted model.ConclusionsSubjects who were non-adherent to their glaucoma medications at baseline as assessed by a MEMS device reported lower VRQoL than adherent subjects at baseline and after 3 years. However, visual acuity was significantly associated with VRQoL. Future studies should assess whether improved adherence to eye-drops impacts VRQoL in patients with glaucoma.

Health- and Vision-Related Quality of Life in Patients with Ocular Hypertension or Primary Open-Angle Glaucoma

2013 ◽  
Vol 229 (4) ◽  
pp. 227-234 ◽  
Author(s):  
Christian Wolfram ◽  
Katrin Lorenz ◽  
Lusine Breitscheidel ◽  
Yves Verboven ◽  
Norbert Pfeiffer
Keyword(s):  
Quality Of Life ◽  
Ocular Hypertension ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Related Quality

scholarly journals Health-related quality of life in patients with primary open-angle glaucoma. An Italian multicentre observational study

2015 ◽  
Vol 94 (5) ◽  
pp. e278-e286 ◽  
Author(s):  
Irene Floriani ◽  
Luciano Quaranta ◽  
Eliana Rulli ◽  
Andreas Katsanos ◽  
Luigi Varano ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related
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