Cataract Surgery in Very Old Patients: A Case-Control Study

Advancements in surgical techniques and increased life expectancy have made cataract surgery more common among very old patients. However, surgical outcomes seem impaired in patients older than 90 years, especially with ocular comorbidities. A retrospective case-control study of 53 eyes of 53 very old patients (mean 92.6 ± 3.0) and 140 eyes of 140 matched patients (mean 75.2 ± 7.6) was undertaken. Groups were matched in terms of gender and systemic and ocular comorbidities. In very old patients, higher phacoemulsification energy (cumulative dissipated energy [CDE], 25.0 ± 22.4 vs. 16.1 ± 10.7, p = 0.01) and rate of intraoperative floppy iris syndrome (IFIS, 9.4% vs. 1.4%, p = 0.02) were observed compared to controls. Uncorrected (UCVA) and best-corrected distance visual acuity (BCVA) gains were significantly poorer among the very old patients than among the control at postoperative day 30 (0.20 ± 0.70 vs. 0.56 ± 0.61 logMAR, p < 0.001 and 0.27 ± 0.64 vs. 0.55 ± 0.62 logMAR, p = 0.006, respectively). Even after including CDE and IFIS as covariates, age remained an independent factor for poor visual gain at 30 days (p < 0.001). Cataract surgery in very old patients may demand more experienced surgeons due to higher nuclear density and the rates of IFIS. Expectations in visual acuity gains should be aligned with the patient’s age.

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Capsule complication during cataract surgery: Case-control study of preoperative and intraoperative risk factors

Journal of Cataract & Refractive Surgery ◽

10.1016/j.jcrs.2009.05.026 ◽

2009 ◽

Vol 35 (10) ◽

pp. 1688-1693 ◽

Cited By ~ 58

Author(s):

Ditte Artzén ◽

Mats Lundström ◽

Anders Behndig ◽

Ulf Stenevi ◽

Eva Lydahl ◽

...

Keyword(s):

Risk Factors ◽

Cataract Surgery ◽

Case Control Study ◽

Case Control ◽

Control Study

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Visual acuity outcomes after deep anterior lamellar keratoplasty: a case-control study

British Journal of Ophthalmology ◽

10.1136/bjo.2009.167528 ◽

2010 ◽

Vol 94 (10) ◽

pp. 1295-1299 ◽

Cited By ~ 40

Author(s):

D. T. H. Tan ◽

A. Anshu ◽

A. Parthasarathy ◽

H. M. Htoon

Keyword(s):

Visual Acuity ◽

Case Control Study ◽

Case Control ◽

Lamellar Keratoplasty ◽

Deep Anterior Lamellar Keratoplasty ◽

Anterior Lamellar Keratoplasty ◽

Control Study

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Current status of eye disorders caused by docetaxel administration every 3 weeks: A case-control study in Japanese patients

Journal of Oncology Pharmacy Practice ◽

10.1177/1078155219868761 ◽

2019 ◽

Vol 26 (3) ◽

pp. 655-665 ◽

Cited By ~ 3

Author(s):

Yusuke Noguchi ◽

Yugo Kawashima ◽

Megumi Maruyama ◽

Hiroko Kawara ◽

Yoko Tokuyama ◽

...

Keyword(s):

Visual Acuity ◽

Confidence Interval ◽

Odds Ratio ◽

Case Control Study ◽

Japanese Patients ◽

Case Control ◽

Current Status ◽

Eye Drops ◽

Eye Disorders ◽

Control Study

Purpose Docetaxel is known to cause eye disorders. In this study, current status of eye disorders caused by docetaxel administration every 3 weeks in Japanese patients was examined. Methods This case-control study targeted patients who were newly administered docetaxel at the Kyoto Okamoto Memorial Hospital between 1 July 2015 and 30 June 2018. Eye disorder occurrence was defined as an event in which the pharmacist confirmed the symptoms in a patient interview and the ophthalmologist diagnosed the disorder. Results Of the 89 subjects, 7 (7.9%) had eye disorders. The symptoms were watering eyes (7.9%), a stye and eye discharge (2.2% each), corneal and conjunctival disorder, visual acuity reduction, and blepharedema (1.1% each). Four patients who presented with watering eyes, eye discharge, or corneal and conjunctival disorder showed improvement with the use of eye drops such as artificial tears. Two patients who presented with a stye showed improvement with the use of oral cefcapene. One patient with mild symptoms showed spontaneous improvement. However, one patient had irreversible visual acuity reduction. The multivariate logistic regression analysis revealed that a cumulative docetaxel dose of ≥300 mg/m2 (odds ratio: 15.50, 95% confidence interval: 1.37–175.00, p = 0.027) and concomitant cyclophosphamide use (odds ratio: 13.20, 95% confidence interval: 1.13–153.00, p = 0.039) were significant risk factors associated with eye disorders. Conclusion In conclusion, it was determined that docetaxel-related eye disorders might be influenced by the cumulative dose of docetaxel and concomitant cyclophosphamide use. In addition, relatively mild symptoms improved with medication.

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Statin Use and Incident Cataract Surgery: A Case-Control Study

Ophthalmic Epidemiology ◽

10.3109/09286586.2015.1077258 ◽

2016 ◽

Vol 23 (1) ◽

pp. 40-45 ◽

Cited By ~ 13

Author(s):

Jay C. Erie ◽

Matthew R. Pueringer ◽

Scott M. Brue ◽

Alanna M. Chamberlain ◽

David O. Hodge

Keyword(s):

Cataract Surgery ◽

Case Control Study ◽

Case Control ◽

Control Study ◽

Statin Use

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Comparative Evaluation of Macular Changes using Optical Coherence Tomography (OCT) following uneventful Cataract Surgery and Cataract Surgery Complicated with Posterior Capsule Rent - A Case- Control Study

International Journal of Contemporary Medical Research [IJCMR] ◽

10.21276/ijcmr.2018.5.12.3 ◽

2018 ◽

Vol 5 (12) ◽

Author(s):

Battula Yallamanda Babu Rao ◽

Vairagyam Rajalingam ◽

Pachalla Sai Rupa Sree

Keyword(s):

Optical Coherence Tomography ◽

Cataract Surgery ◽

Comparative Evaluation ◽

Case Control Study ◽

Case Control ◽

Posterior Capsule ◽

Optical Coherence ◽

Control Study

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Acute myocardial infarction in the elderly. A case-control study with a younger population and review of literature

Monaldi Archives for Chest Disease ◽

10.4081/monaldi.2006.537 ◽

2016 ◽

Vol 66 (1) ◽

Author(s):

Fabrizio Corsini ◽

Anna Scaglione ◽

Maria Iacomino ◽

Giuseppe Mascia ◽

Saverio Melorio ◽

...

Keyword(s):

Myocardial Infarction ◽

Chest Pain ◽

Case Control Study ◽

The Elderly ◽

Case Control ◽

Response To Treatment ◽

Control Group ◽

Retrospective Case ◽

Old Patients ◽

Control Study

Background: ST elevation myocardial infarction (STEMI) in old and old-old patients presents several peculiarities in natural history, delay of hospitalization and response to treatment. Aim of this retrospective case control study was to determine presentation, complications and management of elderly patients with STEMI compared to a younger population. Methods: 462 patients (205 M and 257 F) aged ≥75 years, hospitalized in CCU between 1999 and 2003 for STEMI, were valuated. The control group consisted of 490 consecutive patients (268 M and 222 F) aged 50-70 years. Attention was focused on clinical presentation, complications, management and outcome in elderly compared with younger patients. Results: The mean interval between the onset of symptoms and the arrive in CCU was of 9 hour in the elderly compared to 4,5 hour in the control. Chest pain was less frequent (50% vs 90%) in the elderly; the prevalence of dyspnoea and neurological symptoms was higher in patients >75 years (30% vs 15% and 25% vs 10%). In the elderly, previous angina and AMI, cerebral and peripheral vascular diseases, peripheral and renal failure were frequent. Early severe complications prevailed in the elderly. Thrombolysis was performed only in 39% of the elderly compared to 65% of the control. Significantly higher was cerebral haemorrhage after thrombolysis (4,9% vs 1,8%). Comparable were the mayor extra cranial bleedings. Primary or facilitated PTCA was performed in few patients in the last year. Two weeks mortality was 20%, compared to 6,5% in the control group. Conclusion: The patientes >75 years with STEMI were hospitalized later, had atypical presentation with less chest pain and more cardiac failure, were less likely to receive thrombolysis, had more complications and more cerebral bleedings. Elderly had more associated diseases and in-hospital mortality was higher.

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