scholarly journals AF Inducibility Is Related to Conduction Abnormalities at Bachmann’s Bundle

2021 ◽  
Vol 10 (23) ◽  
pp. 5536
Author(s):  
Lianne N. van Staveren ◽  
Willemijn F. B. van der Does ◽  
Annejet Heida ◽  
Yannick J. H. J. Taverne ◽  
Ad J. J. C. Bogers ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Conduction Block ◽  
Activation Patterns ◽  
Conduction Abnormalities ◽  
Long Term Follow Up ◽  
Simultaneous Activation ◽  
Short And Long Term ◽  
Bachmann’S Bundle

We investigated whether patterns of activation at Bachmann’s bundle are related to AF inducibility. Epicardial mapping of Bachmann’s bundle during sinus rhythm was performed prior to cardiac surgery (192 electrodes, interelectrode distances: 2 mm). Compared to non-inducible patients (N = 20), patients with inducible AF (N = 34) had longer lines of conduction block (18(2–164) mm vs. 6(2–28) mm, p = 0.048), prolonged total activation time (55(28–143) ms vs. 46(24–73) ms, p = 0.012), multiple wavefronts entering Bachmann’s bundle more frequently (64% vs. 37%, p = 0.046) and more often areas of simultaneous activation (conduction velocity > 1.7 m/s, 45% vs. 16%, p = 0.038). These observations further support a relation between conduction abnormalities at Bachmann’s bundle and AF inducibility. The next step is to examine whether Bachmann’s bundle activation patterns can also be used to identify patients who will develop AF after cardiac surgery during both short- and long-term follow-up.

Electroencephalogram-Based Prognosis of Cardiac Surgery — A Long-Term Follow-Up Study

1990 ◽  
pp. 145-151
Author(s):  
Phiroze L. Hansotia ◽  
Percy N. Karanjia ◽  
Richard D. Sautter ◽  
William O. Myers ◽  
Jefferson F. Ray ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Follow Up Study ◽  
Long Term Follow Up

Long-term effectiveness and safety of antiepileptic drugs in children and adults

2021 ◽  
Vol 19 (2) ◽  
pp. 221-228
Author(s):  
Roza M. Shaimardanova ◽  
Rimma G. Gamirova
Keyword(s):  
Valproic Acid ◽  
Antiepileptic Drugs ◽  
Focal Epilepsy ◽  
City Hospital ◽  
Long Term Follow Up ◽  
Short And Long Term ◽  
Long Term Observation ◽  
Patients With Epilepsy

AIM: To conduct a retrospective comparative analysis of the efficacy and safety of epilepsy therapy with antiepileptic drugs. MATERIALS AND METHODS: The analysis of the treatment of 428 patients with epilepsy at the Childrens City Hospital No. 8 in Kazan, receiving antiepileptic drugs. RESULTS: It was found that valproic acid is more effective in the treatment of idiopathic generalized epilepsies compared to focal epilepsies (p = 0.0006). Valproate and carbamazepine were the most effective in the treatment of focal epilepsy with short- and long-term follow-up. Valproic acid is more effective than topiramate (p = 0.02), oxcarbazepine (p = 0.003), and levetiracetam (p = 0.003) in the treatment of focal epilepsy in short- and long-term follow-up. Carbamazepine is more effective than topiramate (p = 0.01), oxcarbazepine (p = 0.02), and levetiracetam (p = 0.001) in the treatment of focal epilepsy in long-term follow-up. It was revealed that more often they complained about side effects when using carbamazepine (63.2%). Levetiracetam was found to be better tolerated compared to valproate (p = 0.0006) and carbamazepine (p = 0.0006). Topiramate is better tolerated than carbamazepine (p = 0.02) and valproate (p = 0.03). Oxcarbazepine is better tolerated than carbamazepine in women (p = 0.04). CONCLUSIONS: When choosing an antiepileptic drug, it is necessary to be guided by the principle: first the basic, and then the drugs of the next generations, in the future, rely on information about the tolerability of the drug. It is necessary to evaluate the therapeutic effect of antiepileptic drugs with long-term observation, and use the criterion of complete absence of seizures as an indicator of the effectiveness of drugs.

Fast-track failure after cardiac surgery: risk factors and outcome with long-term follow-up

2021 ◽  
Author(s):  
Jore Hendrikx ◽  
Maxim Timmers ◽  
Layth Al Tmimi ◽  
Danny F. Hoogma ◽  
Johan De Coster ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Fast Track ◽  
Long Term Follow Up

Longitudinal Observations of the Relationship Between Free Erythrocyte Porphyrins and Whole Blood Lead

PEDIATRICS ◽  
1976 ◽  
Vol 57 (1) ◽  
pp. 54-59
Author(s):  
J. Routt Reigart ◽  
Norris H. Whitlock
Keyword(s):  
Whole Blood ◽  
Blood Lead ◽  
Elevated Blood ◽  
Long Term Follow Up ◽  
Short And Long Term ◽  
First Contact ◽  
The Relationship ◽  
Clinical Category

Short- and long-term comparison of the variations with time of whole blood lead and free erythrocyte porphyrins (FEP) suggests that changes in FEP are slow and predictable whereas blood lead changes are quite unpredictable. However, when FEP suggests a different clinical category from blood lead, the blood lead is likely to change in the direction predicted by the FEP. Comparison of FEP to blood lead at first contact in 349 children with mild elevation of blood lead reliably predicted which children would still have elevated blood lead six weeks later and which would fall or be normal. The observation of long-term follow-up in four groups of children with various combinations of FEP and blood lead indicated that the follow-up blood lead could be predicted to change in the direction indicated by the FEP measurement. The implications for screening for lead poisoning are discussed.

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