scholarly journals Instrumental Evaluation of COVID-19 Related Dysautonomia in Non-Critically-Ill Patients: An Observational, Cross-Sectional Study

2021 ◽  
Vol 10 (24) ◽  
pp. 5861
Author(s):  
Simone Bellavia ◽  
Irene Scala ◽  
Marco Luigetti ◽  
Valerio Brunetti ◽  
Maurizio Gabrielli ◽  
...  
Keyword(s):  
Critically Ill ◽  
Autonomic Dysfunction ◽  
Critically Ill Patients ◽  
Early Stage ◽  
Cross Sectional Study ◽  
Neurological Involvement ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Instrumental Evaluation

Coronavirus disease-19 (COVID-19) is a predominantly respiratory syndrome. Growing reports about a SARS-CoV-2 neurological involvement, including autonomic dysfunction (AD), have been reported, mostly in critically-ill patients, or in the long-COVID syndrome. In this observational, cross-sectional study, we investigated the prevalence of AD in 20 non-critically-ill COVID-19 patients (COVID+ group) in the acute phase of the disease through a composite instrumental evaluation consisting of Sudoscan, automated pupillometry, heart rate variability (HRV), and pulse transit time (PTT). All the parameters were compared to a control group of 20 healthy volunteers (COVID− group). COVID+ group presented higher values of pupillary dilatation velocities, and baseline pupil diameter than COVID− subjects. Moreover, COVID+ patients presented a higher incidence of feet sudomotor dysfunction than COVID− group. No significant differences emerged in HRV and PTT parameters between groups. In this study we observed the occurrence of autonomic dysfunction in the early stage of the disease.

scholarly journals VALUE OF CLINICAL PULMONARY INFECTION SCORE IN CRITICALLY ILL PATIENTS: BETWEEN THE USE OF CHLORHEXIDINE AND PIPER BETLE LINN MOUTHWASH

2018 ◽  
Vol 4 (1) ◽  
pp. 76-82
Author(s):  
Irfany Nurul Hamid ◽  
Rr Sri Endang Pujiastuti ◽  
Dwi Ari Widigdo ◽  
Djenta Saha
Keyword(s):  
Treatment Group ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Pulmonary Infection ◽  
Cross Sectional Study ◽  
Piper Betle ◽  
Ventilator Associated Pneumonia ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean

Background: One of the complications of ventilator use in patients in Intensive Care Unit (ICU) is Ventilator-Associated Pneumonia (VAP). Oral hygienes is one of the methods to prevent VAP.Objective: The objective of this study was to compare the value of clinical infection score (CPIS) in critically ill patients after given oral hygiene using chlorhexidine and Piper betle Linn mouthwash.Methods: This was an observational study with cross-sectional study design, which consisted of two intervention groups. Thirty respondents were selected using total sampling, with 15 respondents randomly assigned in each group. Independent t-test was used for data analysis.Results: Findings showed that  the mean of CPIS in the Piper betle Linn group was 3.80 and the mean of CPIS in the chlorhexidine group was 4.07.Conclusion: CPIS in the treatment group using Piper betle Linn mouthwash was lower than the mean of CPIS in the treatment group using clorhexidine. 

scholarly journals Low Serum Zinc in Critically Ill Patients Fed Oral and Enteral Nutrition in a Brazilian Terciary Hospital: A Cross-Sectional Study

2021 ◽  
Vol 6 (6) ◽  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Medical Records ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Oral Nutrition ◽  
Flame Atomic Absorption ◽  
Zinc Levels

Purpose: Since zinc is required for immunity and inflammation regulations, this paper aimed to investigate serum zinc levels in critically ill patients receiving Enteral (EN) and Oral Nutrition (ON) and correlate these values with demographic, clinical and laboratory parameters. Material and Methods: This is a cross-sectional study. Researchers collected data from electronic medical records in Intensive Care Units (ICUs) of a Brazilian tertiary hospital. Flame Atomic Absorption Spectrophotometry measured serum zinc (normal range: 70-120 mcg/dl). Evaluated variables: age, sex, diagnoses, ICU type, iron, hemoglobin, leukocytes, C-reactive protein, severity score, and mortality. Results: Researches assessed 203 medical records. Mean zinc score was low (EN: 59.13 ±16.26 mcg/dl; ON: 64.75 ±16.80 mcg/dl; p= 0.010). Mean age was high (EN: 77.48 ± 16.26 years; ON: 75.01 ± 13.03 years; p= 0.012). Iron was positively correlated with zinc in EN (p= 0.012). Age was correlated negatively with zinc in ON (p=0.001). Hemoglobin was correlated positively with zinc in EN (p= 0.007) and ON (p= 0.018). Conclusions: Most of the ICU patients had low zinc. EN had lower zinc levels than ON. L

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