scholarly journals Relationship of Postoperative Pain and PONV after Minimally Invasive Surgery with the Serotonin Concentrations and Receptors’ Gene Polymorphisms

2021 ◽  
Vol 11 (9) ◽  
pp. 833
Author(s):  
Natalia Ignaszak-Kaus ◽  
Antoni J. Duleba ◽  
Aleksandra Mrozikiewicz ◽  
Grażyna Kurzawińska ◽  
Agata Różycka ◽  
...  
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Minimal Invasive ◽  
Steady Increase ◽  
Infertile Women ◽  
Postoperative Symptoms ◽  
Post Operative Nausea ◽  
Postoperative Complaints ◽  
Relationship Of

(1) Background: there is a steady increase in the number of procedures performed via minimally invasive surgery, which have many benefits, but post-operative nausea and vomiting (PONV) and significant pain are still a common problem (2) Methods: 300 infertile women (18–40 years old) undergoing minimal invasive surgery. Interventions: laparoscopy and hysteroscopy performing, evaluation of postoperative symptoms, serotonin concentrations assessment, identify genetic polymorphisms. (3) Results: serotonin concentrations were significantly lower among women who required opioids (p = 0.006). The presence of the GG genotype in the rs6318 polymorphism of the 5HTR2C gene had a protective effect on PONV (OR = 0.503; C.I. = [0.300–0.841]; p = 0.008), when the GG variant of the rs11214763 polymorphism of the 5HTR3B gene, when the risk of PONV was 1.65-fold higher (OR = 1.652; C.I. = [1.003–2.723]; p = 0.048). Pain intensity was significantly higher among women with GG genotype of the rs6296 polymorphism of the 5HTR1B gene (OR = 1.660; C.I. = [1.052–2.622]; p = 0.029).; (4) Conclusions: the evaluation of serotonin concentration predicts requirement for opioid pain relief medication. The polymorphisms of the serotonin receptors affect the intensity of postoperative complaints.

scholarly journals The Advances of Laparoscopic Gastrectomy for Gastric Cancer

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Yeon-Ju Huh ◽  
Joo-Ho Lee
Keyword(s):  
Gastric Cancer ◽  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Laparoscopic Gastrectomy ◽  
Minimal Invasive ◽  
Long Term Outcomes ◽  
Short And Long Term

Laparoscopic gastrectomy is evolving. With the increasing expertise and experience of oncologic surgeons in the minimally invasive surgery for gastric cancer, the indication for laparoscopic gastrectomy is expanding to advanced cases. Many studies have demonstrated the benefits of minimally invasive surgery, including reduced risk of surgery-related injury, reduced blood loss, less pain, and earlier recovery. In order to establish concrete evidence for the suitability of minimal invasive surgery for gastric cancer, many multicenter RCTs, comparing the short- and long-term outcomes of laparoscopic versus open surgery, are in progress. Advances in laparoscopic gastrectomy are moving toward increasingly minimally invasive approaches that enable the improvement of the quality of life of patients, without compromising on oncologic safety.

scholarly journals Outcome of minimal invasive surgery approach for spine infection: a systematic review

2019 ◽  
Vol 7 (11) ◽  
pp. 4422
Author(s):  
Ketut Gede Mulyadi Ridia
Keyword(s):  
Systematic Review ◽  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Spine Surgery ◽  
Invasive Surgery ◽  
Minimal Invasive Surgery ◽  
Minimal Invasive ◽  
Spine Infection ◽  
Minimally Invasive Spine

The concept of minimally invasive surgery has gained increasing popularity in the last several decades, are being introduced as an alternative to limit the surgical complications while achieving best possible outcome. While minimally invasive spine surgery holds promise for lower blood loss, faster patient recovery, shorter hospital stays, and the potential to transition procedures to the ambulatory setting, safety in spinal surgery remains paramount and has (appropriately) tempered some of the enthusiasm for the results of aggressive early adapters. Until now, there has been no literature summarizing the evidence of MIS outcome in treating spondylitis TB of the bone. The purpose of this systematic review was to investigate the outcome of minimal invasive surgery approach for spine infection. authors comprehensively searched PubMed, EMBASE, and Cochrane Library to search for studies about minimally invasive surgery as management of tuberculous spondylitis up to June 7th, 2019. The selection of appropriate studies was performed by independent investigators based on PRISMA guideline. Given the limited number of studies, there was no restriction in terms of patient’s demographics, the specific minimal invasive surgical method, and publication status. Authors identified the method for minimally invasive approach and open approach, the functional outcome, intraoperative outcome, radiological outcome, length of stay, follow up period, and complication. Authors found 81 articles from database. After evaluating full text, 8 articles (346 patients) were found to be eligible. More than 110 patients were treated with open spine surgery, while more than 270 patients were treated using minimally invasive spine surgery the minimal invasive methods were posterior pedicle screws fixation, plate fixation, lateral nail bar fixation, and bilateral pedicle screw fixation. The visualization methods include C-arm fluoroscopy, X-ray fluoroscopy. The follow-up period ranges from 1 to 40 months. The functional outcome were found to be satisfying with minimal complications. MIS yielded satisfactory result in comparison to conventional open surgery for spine infection. More long term future studies should be conducted to in order to search for more solid evidence regarding this claim.

Modeling and Design of a Piezoelectric Forceps Actuator for Meso∕Micro Grasping

2006 ◽  
Vol 1 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Ken Susanto ◽  
Bingen Yang
Keyword(s):  
Genetic Algorithm ◽  
Mathematical Model ◽  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Significant Role ◽  
Invasive Surgery ◽  
Biological Tissues ◽  
Soft Objects ◽  
Grasping Force ◽  
Relationship Of

Meso∕micro grasping of tiny soft objects such as biological tissues, which ranges from hundreds to thousands of micro-millimeters in dimension, plays a significant role in the fields of tele-surgery, minimally invasive surgery (MIS), and biomedical instrumentation. Recently, the authors proposed a novel piezoelectric forceps actuator (PFA), which is capable of grasping delicate soft objects. One of the advantages of the PFA over conventional MIS forceps lies in that it can be remotely controlled to achieve precision deflection and grasping force. Furthermore, it does not have any moving parts such as gears and hinges, and hence avoids problems in operation like friction, backlash, lubrication, leakage, and sterilization. In this paper, a mathematical model of the PFA is derived, based on which genetic algorithm (GA) is applied to optimize the grasping force-deflection relationship of the actuator. The model developed is experimentally verified on a prototype of the PFA.

scholarly journals P038 MINIMALLY INVASIVE SURGERY & INCARCERATED INGUINAL HERNIA. CAN WE COMBINE THEM?

2021 ◽  
Vol 108 (Supplement_8) ◽  
Author(s):  
Jorge Zárate Gómez ◽  
Pedro Álvarez de Sierra Hernández ◽  
David Fernández Luengas ◽  
Silvia Conde Someso ◽  
Guillermo Supelano Eslait ◽  
...  
Keyword(s):  
Minimally Invasive Surgery ◽  
Inguinal Hernia ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Intestinal Ischemia ◽  
Intestinal Resection ◽  
Minimal Invasive ◽  
Incarcerated Inguinal Hernia ◽  
Multiple Treatment ◽  
Preperitoneal Approach

Abstract Aim After a long experience of more than 20 years in TEP hernioplasty we explore if it can also be suitable for emergency patients. Material and Methods We present different laparoendoscopic schemes that we have used in our Hospital to treat strangulated inguinal hernia according to clinical and radiological findings. Results TEP in now assumed to be one of the best options in scheduled surgery to treat inguinal hernia. Is now the time to change the paradigm by using it also in emergency surgery? Incarcerated inguinal hernia presents two problems: first of all the clinical emergency, an irreducible inguinal bulge that causes pain, obstruction and bowel ischemia; and second, the need to repair inguinal wall. While treating both problems, we have explored different minimally invasive surgery approaches according to each patient´s characteristics and the preoperative risk of intestinal resection based on CT findings. To reduce the incarcerated bulge, we use a laparoendoscopic methods. After a preperitoneal dissection, and with the help of external maneuvers, we try to reduce the content. If we are not successful, a quelotomy becomes necessary. To treat the inguinal defect we use TEP or TAPP approaches. Conclusions We seek to show that endoscopic preperitoneal approach in an incarcerated inguinal hernia is safe and possible, allowing us to maintain minimal invasive techniques. Laparoscopy allows us to explore and to treat possible complications of intestinal ischemia with no need of laparotomy. Multiple treatment schemes are possible for inguinal incarcerated hernia. The choice must be made according to the surgeońs experience, patient´s characteristic and the risk of intestinal ischemia.

V1695: Minimizing Minimally Invasive Surgery: the Three Port Robotic Pyeloplasty

2004 ◽  
Vol 171 (4S) ◽  
pp. 448-448
Author(s):  
Farjaad M. Siddiq ◽  
Patrick Villicana ◽  
Raymond J. Leveillee
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Robotic Pyeloplasty
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