Usefulness of Magnetic Mallet in Oral Surgery and Implantology: A Systematic Review

This systematic review aimed to answer the question: “Is the use of magnetic mallet effective in oral and implant surgery procedures in terms of tissue healing, surgery outcome, and complication rate compared to traditional instruments?” A literature search of PubMed, Scopus, and Web of Science databases (articles published until 1 October 2021) was conducted, in accordance with the PRISMA statement, using the keywords “magnetic mallet”, “electric mallet”, “oral surgery”, “implantology”, and “dental implant”. Of 252 articles, 14 were included in the review (3 for teeth extraction, and 11 for implant dentistry). Out of a total of 619 dental extractions (256 patients) performed with the magnetic mallet (MM), no complications were reported. Implants inserted totaled 880 (525 patients): 640 in the MM groups (382), and 240 in control groups (133). The survival rate of implants was 98.9% in the MM groups, and 95.42% in the control groups. Seven patients experienced benign paroxysmal positional vertigo after implant surgery, all in control groups. Results are not sufficient to establish the effectiveness of MM in oral and implant surgery procedures. Randomized controlled trials with a large sample size are needed.

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A Systematic Review on the Feasibility of Salivary Biomarkers for Alzheimer’s Disease

10.21203/rs.2.17674/v2 ◽

2019 ◽

Author(s):

Mohamed Bouftas

Keyword(s):

Systematic Review ◽

Cumulative Effect ◽

Csf Biomarkers ◽

Large Sample Size ◽

Inclusion Criteria ◽

Control Groups ◽

Salivary Biomarkers ◽

And Control ◽

Saliva Composition ◽

Selection Of

Abstract Background: Early AD diagnosis is critical for ameliorating prognosis and treatment. The analysis of CSF biomarkers yields accurate results, but it necessitates a lumbar puncture procedure. Screening for peripheral biomarkers in saliva is advantageous since this medium is noninvasive and inexpensive to obtain. The objective of this systematic review is to analyze saliva biomarker studies which aim to diagnose AD. Methods: Titles, abstracts, and reference lists for publications from February 2004 to March 2019 were screened for by searching Google Scholar and PubMed. The inclusion criteria involved published studies that consisted of both AD and control groups. Results: 77 studies were screened, and 13 publications fulfilled the inclusion criteria. These selected publications were scrutinized and included in this review. Numerous biomarkers were analyzed, including Aβ42, tau, and various salivary metabolites. Conclusion: Aβ42, tau, lactoferrin, and various metabolites might serve as a reliable biomarkers for AD diagnosis. However, these studies must be replicated with a large sample size. It is also important to standardize the analytical methods of measuring salivary biomarkers to establish coherence for the selection of valid AD biomarkers. Saliva composition can be affected by production rate, circadian rhythms, and oral health, so their cumulative effect on the accuracy of saliva testing requires further investigation. Keywords: Alzheimer, biomarker, saliva

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A Systematic Review on the Feasibility of Salivary Biomarkers for Alzheimer’s Disease

10.21203/rs.2.17674/v1 ◽

2019 ◽

Author(s):

Mohamed Bouftas

Keyword(s):

Systematic Review ◽

Cumulative Effect ◽

Csf Biomarkers ◽

Large Sample Size ◽

Inclusion Criteria ◽

Control Groups ◽

Salivary Biomarkers ◽

And Control ◽

Saliva Composition ◽

Selection Of

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Efficacy and Safety of Guizhi Decoction AssociatedFormulas for Allergic Rhinitis: A Systematic Review

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2021/3548740 ◽

2021 ◽

Vol 2021 ◽

pp. 1-8

Author(s):

Shasha Yang ◽

Qinwei Fu ◽

Hua Deng ◽

Jing Wu ◽

Qinxiu Zhang ◽

...

Keyword(s):

Systematic Review ◽

Allergic Rhinitis ◽

Systematic Reviews ◽

Western Medicine ◽

Effective Rate ◽

Placebo Control ◽

Large Sample Size ◽

Efficacy And Safety ◽

Control Groups ◽

Guizhi Decoction

In this study, we aim to evaluate the efficacy and safety of Guizhi Decoction associated formulas for the treatment of allergic rhinitis. A total of seven online databases were searched to collect studies published up to Feb 23rd, 2020. Study quality of each included article was evaluated by the Cochrane Collaboration risk of bias tool. Systematic reviews were conducted based on the Cochrane systematic review method by using RevMan 5.3 Software. Among the included trials, Guizhi Decoction associated formulas alone (or plus Western medicine, or acupoint-based therapy) were main therapies in experimental groups. Interventions in control groups include Western medicine, Guizhi Decoction associated formulas alone, Chinese patent medicine, and placebo control. Primary outcomes in this study include recovery rate, accumulative marked effective rate, accumulative effective rate, and recurrence rate. Finally, 23 trials involving 2281 participants were included. Results of systematic reviews show that Guizhi Decoction and associated formulas alone, plus Western medicine or plus acupoint-based therapies, were significantly better compared with using Western medicine alone in terms of efficacy. In addition, the formulas plus nasal TCM fumigation therapy could improve effective rate for AR treatment compared to using the formulas alone. More types and cases of adverse events were reported in the control groups (Western medicine alone), but events of included trials were all mild and did not need specific medical intervention. More RCTs of high quality, and large sample size, with appropriate blinding methods or nonblinded pragmatic trials of Guizhi Decoction and associated formulas for AR are needed.

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REGENERAÇÃO ÓSSEA GUIADA DE ALVÉOLOS DE EXTRAÇÃO DENTÁRIO- UMA REVISÃO

International Journal of Science Dentistry ◽

10.22409/ijosd.v1i45.319 ◽

2016 ◽

Vol 1 (45) ◽

Author(s):

Bruno Pires Miranda

Keyword(s):

Bone Regeneration ◽

Tooth Extraction ◽

Oral Surgery ◽

Guided Bone Regeneration ◽

The Body ◽

Synthetic Material ◽

Dynamic Changes ◽

Tooth Socket ◽

Ability To Regenerate ◽

Implant Dentistry

Resumo O osso é um tecido conjuntivo especializado, vascularizado e dinâmico que se modifica ao longo do organismo. Quando lesado, possui uma capacidade única de regeneração e reparação sem a presença de cicatrizes, mas em algumas situações devido tamanho do defeito ósseo não se regenera por completo. Assim, se faz necessária a realização de procedimentos de regeneração óssea guiada. Para isso, o implantodontista deve conhecer as bases biológicas da regeneração óssea guiada alveolar e suas indicações. Nesta revisão foram abordadas indicações, vantagens e tipos de biomateriais utilizados para preenchimento do alvéolo dentário imediatamente após a extração dentária sempre que o objetivo for à reabilitação através da instalação de implantes. Mesmo este, biomateriais, apresentando inúmeras qualidades, estudos ainda devem ser feitos a fim de obter a cada dia, um material sintético compatível com o tecido ósseo perdido em quantidades adequadas sem necessitar de cirurgias extra-bucais.ABSTRACT Bone is a specialized vascularized connective tissue that dynamic changes throughout the body. When injured, it has a unique ability to regenerate and repair without the presence of scars, but in some situations due to size of the bone defect does not regenerate completely. Thus, it is necessary to perform guided bone regeneration procedures. For this, the implant dentistry must know the biological bases of alveolar guided bone regeneration and its indications. In this review were addressed indications, advantages and types of biomaterials used for filling the tooth socket immediately after the tooth extraction whenever the goal is rehabilitation through implants installation. Even this, biomaterials, having several qualities, further studies must be done to obtain each day, a synthetic material compatible with the bone tissue lost in proper amounts without the need of extra-oral surgery.

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EXPRESS: Stroke risk following traumatic brain injury: systematic review and meta-analysis

International Journal of Stroke ◽

10.1177/17474930211004277 ◽

2021 ◽

pp. 174749302110042

Author(s):

Grace Mary Turner ◽

Christel McMullan ◽

Olalekan Lee Aiyegbusi ◽

Danai Bem ◽

Tom Marshall ◽

...

Keyword(s):

Systematic Review ◽

Stroke Risk ◽

Meta Analysis ◽

Vitamin K Antagonists ◽

Cochrane Library ◽

Control Group ◽

Large Sample Size ◽

Hazard Ratios ◽

Increased Risk ◽

The Cochrane Library

Aims To investigate the association between TBI and stroke risk. Summary of review We undertook a systematic review of MEDLINE, EMBASE, CINAHL, and The Cochrane Library from inception to 4th December 2020. We used random-effects meta-analysis to pool hazard ratios (HR) for studies which reported stroke risk post-TBI compared to controls. Searches identified 10,501 records; 58 full texts were assessed for eligibility and 18 met the inclusion criteria. The review included a large sample size of 2,606,379 participants from four countries. Six studies included a non-TBI control group, all found TBI patients had significantly increased risk of stroke compared to controls (pooled HR 1.86; 95% CI 1.46-2.37). Findings suggest stroke risk may be highest in the first four months post-TBI, but remains significant up to five years post-TBI. TBI appears to be associated with increased stroke risk regardless of severity or subtype of TBI. There was some evidence to suggest an association between reduced stroke risk post-TBI and Vitamin K antagonists and statins, but increased stroke risk with certain classes of antidepressants. Conclusion TBI is an independent risk factor for stroke, regardless of TBI severity or type. Post-TBI review and management of risk factors for stroke may be warranted.

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Effect of photobiomodulation in secondary intention gingival wound healing—a systematic review and meta-analysis

BMC Oral Health ◽

10.1186/s12903-021-01611-2 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Pooya Ebrahimi ◽

Mahdi Hadilou ◽

Ferdos Naserneysari ◽

Amirmohammad Dolatabadi ◽

Rana Tarzemany ◽

...

Keyword(s):

Systematic Review ◽

Wound Healing ◽

Clinical Trials ◽

Randomized Clinical Trials ◽

Meta Analysis ◽

Healing Process ◽

Adjunctive Treatment ◽

Control Groups ◽

Secondary Intention ◽

Post Operative Pain

Abstract Background Photobiomodulation is widely being used to improve the wound healing process in dentistry and a vast majority of studies have proven its benefits. But there are plenty of knowledge gaps according to the optimal laser characteristics which should be used to maximize the healing effects of lasers. The goal of this systematic review and meta-analysis was to determine the effect of photobiomodulation (PBM) as an adjunctive treatment to periodontal therapies to evaluate secondary intention gingival wound healing and post-operative pain. Methods Five databases (PubMed, Embase, Scopus, ProQuest, and Web of Sciences) were searched up to November 30, 2020, for clinical trials that reported the result of the application of PBM on secondary gingival healing wounds and post-operative pain and discomfort after periodontal surgeries. Two independent reviewers selected the eligible studies and the outcomes of interest were extracted. The quality of eligible studies was assessed using the Cochrane Handbook for Systematic Reviews of Interventions. Results Ultimately, twelve studies were included in this review. The application of PBM as an adjunct to periodontal surgeries resulted in a significant improvement in wound healing indices. The Landry wound healing index at the 7th post-operative day was significantly improved (SMD = 1.044 [95% CI 0.62–1.46]; p < 0.01) in PBM + surgery groups compared to the control groups. There was also a statistically significant increase in the complete wound epithelialization (RR = 3.23 [95% CI 1.66–6.31]; p < 0.01) at the 14th post-operative day compared to the control groups. The methods used to assess the post-operative pain were heterogeneous, and therefore the results were limited which made the meta-analysis for post-operative pain assessment not possible. Conclusion Based on the results of this review, PBM can be effectively used as a method to improve secondary intention wound healing. High-quality randomized clinical trials, however, are needed in the future to identify the optimal PBM irradiation parameters and the effect of PBM on post-operative pain.

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Systematic review of the ingestion of fructooligosaccharides on the absorption of minerals and trace elements versus control groups

Clinical Nutrition ESPEN ◽

10.1016/j.clnesp.2020.11.007 ◽

2020 ◽

Author(s):

G.T. Costa ◽

Q.D.J.S. Vasconcelos ◽

G.C. Abreu ◽

A.O. Albuquerque ◽

J.L. Vilar ◽

...

Keyword(s):

Systematic Review ◽

Trace Elements ◽

Control Groups ◽

Minerals And Trace Elements

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Effects of Recreational Small-Sided Soccer Games on Bone Mineral Density in Untrained Adults: A Systematic Review and Meta-Analysis

Healthcare ◽

10.3390/healthcare9040457 ◽

2021 ◽

Vol 9 (4) ◽

pp. 457

Author(s):

Filipe Manuel Clemente ◽

Rodrigo Ramirez-Campillo ◽

Hugo Sarmento ◽

Daniel Castillo ◽

Javier Raya-González ◽

...

Keyword(s):

Bone Mineral Density ◽

Systematic Review ◽

Active Control ◽

Bone Mineral ◽

Meta Analysis ◽

Adult Population ◽

Noncommunicable Disease ◽

Lower Limbs ◽

Mineral Density ◽

Control Groups

This systematic review with meta-analysis was conducted to assess the effects of small-sided games (SSG)-based training programs on bone mineral density (BMD) in untrained adults. The data sources utilized were Cochrane, Embase, Medline (PubMed), Scopus, SPORTDiscus, and Web of Science. The study eligibility criteria were: (i) untrained adults (>18 years old) of any sex, with or without a noncommunicable disease; (ii) SSG-based programs with a minimum duration of four weeks and no restrictions regarding frequency (number of sessions per week); (iii) passive or active control groups; (iv) pre-post values of BMD; (v) only randomized controlled trials; and (vi) only original and full-text studies written in English. The database search initially yielded 374 titles. From those, nine articles were eligible for the systematic review and meta-analysis. The age of included population varied from a minimum of 20 and a maximum of 71 years old. Non-significant differences between SSG and passive and active control groups on total BMD (ES = 0.14; p = 0.405 and ES = 0.28; p = 0.05, respectively). Meanwhile, significant differences in favor of SSGs vs. passive and control groups were detected, evidencing an improvement of BMD in lower limbs of the adult population for both sexes (ES = 0.26; p = 0.05 and ES = 0.28; p = 0.156, respectively). As conclusions, SSGs can be used as a non-pharmacological alternative to increase the BMD in the lower limbs despite having no significant impact on total body BMD. Careful generalization should be done of the level of heterogeneity.

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Carbon dioxide levels in neonates: what are safe parameters?

Pediatric Research ◽

10.1038/s41390-021-01473-y ◽

2021 ◽

Author(s):

Sie Kei Wong ◽

M. Chim ◽

J. Allen ◽

A. Butler ◽

J. Tyrrell ◽

...

Keyword(s):

Carbon Dioxide ◽

Systematic Review ◽

Side Effects ◽

Preterm Infants ◽

Periventricular Leukomalacia ◽

List Type ◽

Permissive Hypercapnia ◽

Prisma Statement ◽

Carbon Dioxide Levels ◽

Online Software

Abstract There is no consensus on the optimal pCO2 levels in the newborn. We reviewed the effects of hypercapnia and hypocapnia and existing carbon dioxide thresholds in neonates. A systematic review was conducted in accordance with the PRISMA statement and MOOSE guidelines. Two hundred and ninety-nine studies were screened and 37 studies included. Covidence online software was employed to streamline relevant articles. Hypocapnia was associated with predominantly neurological side effects while hypercapnia was linked with neurological, respiratory and gastrointestinal outcomes and Retinpathy of prematurity (ROP). Permissive hypercapnia did not decrease periventricular leukomalacia (PVL), ROP, hydrocephalus or air leaks. As safe pCO2 ranges were not explicitly concluded in the studies chosen, it was indirectly extrapolated with reference to pCO2 levels that were found to increase the risk of neonatal disease. Although PaCO2 ranges were reported from 2.6 to 8.7 kPa (19.5–64.3 mmHg) in both term and preterm infants, there are little data on the safety of these ranges. For permissive hypercapnia, parameters described for bronchopulmonary dysplasia (BPD; PaCO2 6.0–7.3 kPa: 45.0–54.8 mmHg) and congenital diaphragmatic hernia (CDH; PaCO2 ≤ 8.7 kPa: ≤65.3 mmHg) were identified. Contradictory findings on the effectiveness of permissive hypercapnia highlight the need for further data on appropriate CO2 parameters and correlation with outcomes. Impact There is no consensus on the optimal pCO2 levels in the newborn. There is no consensus on the effectiveness of permissive hypercapnia in neonates. A safe range of pCO2 of 5–7 kPa was inferred following systematic review.

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Evaluation of the Nasolabial Angle in Orthodontic Diagnosis: A Systematic Review

Applied Sciences ◽

10.3390/app11062531 ◽

2021 ◽

Vol 11 (6) ◽

pp. 2531

Author(s):

Vincenzo Quinzi ◽

Licia Coceani Paskay ◽

Nicola D’Andrea ◽

Arianna Albani ◽

Annalisa Monaco ◽

...

Keyword(s):

Systematic Review ◽

Hyaluronic Acid ◽

Class Ii ◽

Cochrane Library ◽

Class Iii ◽

Palatal Expansion ◽

Rapid Palatal Expansion ◽

Nasolabial Angle ◽

Registration Number ◽

Teeth Extraction

Background: This study is a systematic literature review aiming at identifying the variation of the average nasolabial angle (NLA) in various orthodontic situations. The NLA is one of the key factors to be studied in an orthodontic diagnosis for the aesthetics of the nose and facial profile. Methods: Out of 3118 articles resulting from four search engines (PubMed, Cochrane Library, Turning Research Into Practice (TRIP) and SciELO), the final study allowed the analysis and comparison of only 26 studies. These included studies have considered the NLA in the following cases: teeth extraction, class II malocclusion, class III malocclusion, rapid palatal expansion (RPE), orthognathic surgery, and non-surgical rhinoplasty with a hyaluronic acid filler. Results: The results indicate that teeth extraction and the use of hyaluronic acid fillers significantly affect the NLA. Conclusions: This systematic review shows that a statistically significant change in NLA values occurs in: extractive treatments of all four of the first or second premolars in class I patients; in class II patients with upper maxillary protrusion; in patients with maxillary biprotrusion, except for cases of severe crowding; and in patients undergoing non-surgical rhinoplasty with a hyaluronic acid filler. Trial registration number: PROSPERO CRD42020185166

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