scholarly journals Non-Respiratory Symptoms of Patients Infected with SARS-CoV-2 (Coronavirus Disease 2019): Lessons from Their Initial Presentation at the Hospital

Medicina ◽  
2021 ◽  
Vol 57 (4) ◽  
pp. 344
Author(s):  
Angelo V. Vasiliadis ◽  
Maria Tsatlidou ◽  
Dimitrios Metaxiotis ◽  
Charalampos Psomiadis ◽  
Anastasios Beletsiotis ◽  
...  
Keyword(s):  
Medical Records ◽  
Respiratory Symptoms ◽  
Clinical Laboratory ◽  
Study Data ◽  
Initial Presentation ◽  
Musculoskeletal Symptoms ◽  
Laboratory Findings ◽  
The Mean ◽  
Age Range ◽  
Anatomic Region

Background and objectives: As the COVID-19 pandemic spreads, it is becoming increasingly evident that this coronavirus is not limited to the respiratory system and that the musculoskeletal system can also be affected. The purpose of the present study was to describe non-respiratory symptoms of laboratory-confirmed COVID-19 cases. Materials and Methods: All patients with SARS-CoV-2 admitted to our hospital, between 1 August and 30 September 2020, were included in this retrospective study. Data were extracted from medical records. Epidemiological, clinical, laboratory and radiological characteristics at the initial presentation at the hospital were collected and analyzed. Results: A total of 79 COVID-19 patients were enrolled. The mean age of the patients was 44.08 years (age range, 18–87 years) and 59.5% were male. The most common symptoms were fatigue in 60 (75.9%) patients, followed by fever (73.4%), myalgia (51.9%), cough (41.8%), anosmia (38%) and arthralgia (36.7%). The muscles of the upper back and the knee joint were the most painful anatomic region and joint, respectively. The laboratory findings on admission showed that D-dimer, CRP and procalcitonin levels were increased, without significant gender differences (p > 0.05). Chest imaging demonstrated pneumonia in 20 (25.3%) patients. Conclusions: Our results indicate that from the onset of the symptoms of COVID-19 patients, musculoskeletal symptoms, such as fatigue, myalgia and arthralgia, were present in three-quarters of all patients. These findings could help elaborate updated triage and admission protocols for suspect COVID-19 patients at the hospital and Emergency Department presentation.

scholarly journals Assessment of Children Exposed to Maras Powder Intoxication

Folia Medica ◽  
2020 ◽  
Vol 62 (3) ◽  
pp. 515-518
Author(s):  
Tahir Dalkiran ◽  
Mehmed Mustafa Özaslan ◽  
Can Acipayam ◽  
Yaşar Kandur ◽  
Velid Unsal
Keyword(s):  
Medical Records ◽  
Treatment Approach ◽  
Treatment Strategies ◽  
Clinical Effects ◽  
Oral Ingestion ◽  
Male Patients ◽  
The Mean ◽  
The Difference ◽  
Maras Powder ◽  
Age Range

Introduction: A smokeless tobacco known as Maras powder (MP) is commonly consumed in the southern region of Turkey. To the extent of our knowledge, no previous study in literature has reported acute MP intoxication in children. Aim: Our aim was to determine the clinical effects and treatment strategies of MP poisoning in children.Materials and methods: We retrospectively reviewed the medical records of children <18 years of age with MP intoxication who were followed up in the Intensive Care Unit between January 2016 and April 2018 in our center. Results: Forty-one patients (M/F= 25/16) were included in this study. The mean age was 13.2&plusmn;22.4 months (age range: 7 to 30 months). The patients presented with vomiting (n=23, 56%), cough (n=17, 41.5%), loss of consciousness (n=11, 26.8%), respiratory distress (n=6, 14.6%), convulsion (n=7, 17%), cyanosis (n=1, 2.4%), and abdominal pain (n=1, 2.4%) following oral ingestion of the substance. On their physical examination all patients with convulsion were in a comatose state. Thirty-two patients (78%) had tachycardia; 15 patients (36.5%) had pharyngeal hyperemia; and three (7.3%) had hiccups. Although the female patients had a lesser rate of symptoms than male patients, the difference was not statistically significant. Conclusions: Our aim was to inform the doctors about the clinical picture that develops after taking this substance and contribute to the understanding of the treatment approach.

scholarly journals Clinical Characteristics, Dynamic Profile of Radiology and Laboratory Findings in Coronavirus Disease 2019

2020 ◽  
Author(s):  
ailing liu ◽  
Jing Zhang ◽  
Wei Qiao ◽  
Wei Zang ◽  
Yingying Zhang ◽  
...  
Keyword(s):  
Clinical Laboratory ◽  
Laboratory Data ◽  
Oxygenation Index ◽  
Laboratory Findings ◽  
Single Centre Study ◽  
History Of ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Dynamic Profile

Abstract Background Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, more and more data from different area and different stages of disease have been needed.Methods In this retrospective, single-centre study, we included all 38 confirmed cases of Covid-19 in Weihai from Jan 24 to Feb 24, 2020. Patients were divided into group A by normal Oxygenation Index (OI), group B by abnormal OI (less than 400 mmHg).The dynamic changes in clinical laboratory parameters were tracked from day 1 to day 32 after the onset of the disease at 4-day intervals. Cases were analyzed for clinical, radiological features and laboratory data. Outcomes were followed up until Feb 24, 2020.Results 38 patients with Covid-19 were included in this study, 68.42% patients were family clustered, and 97.37% patients had a history of exposure. The mean days between exposure and onset were about 5 days. Most patients were men, mean age was 43 years, 52.6% patients had chronic diseases. Most patients had fever or cough, about a third of patients had expectoration or fatigue, and 5 (13.16%) patients had shortness of breath.

scholarly journals Clinical Laboratory Profile of Blood Culture Proven Enteric Fever in Children

2018 ◽  
Vol 38 (3) ◽  
pp. 153-156
Author(s):  
Subhash Chandra Shah ◽  
Prashank Shree Neupane ◽  
Anusmriti Guragain ◽  
Ajaya Kumar Dhakal
Keyword(s):  
Blood Culture ◽  
Enteric Fever ◽  
Clinical Laboratory ◽  
Salmonella Typhi ◽  
Total Leucocyte Count ◽  
Laboratory Findings ◽  
Clinical Presentations ◽  
Associated Symptoms ◽  
Laboratory Profile ◽  
The Mean

Introduction: Enteric fever has diverse clinical presentations and laboratory findings and blood culture is gold standard for diagnosis in the children. This study was done to analyse clinical profile and laboratory findings in culture proven enteric fever. Material and Methods: The study was descriptive observational study carried out in the patient aged 14 years of age or less admitted with culture proven enteric fever admitted in a Paediatric ward of a tertiary medical centre in Lalitpur, Nepal from April 2009 to February 2018. Results: Forty children with blood culture proven were enrolled in the study. All children had fever with the mean duration of 5.3 days (1-14). The most common associated symptoms were gastrointestinal which included anorexia (47.5%), pain abdomen (37.5%), vomiting (37.5%), diarrhoea (15%) and constipation (5 %). Splenomegaly (25%) and hepatomegaly (17.5%) were the commonest signs. The majority of children (80%) had normal total leucocyte count and 32.5% of them had anaemia. There were no children with thrombocytopenia. Salmonella typhi and Salmonella paratyphi A were isolated in 70% and 30% of children respectively. None of the isolates showed drug resistance against ceftriaxone, chloramphenicol, cotrimoxazole, gentamicin, norfloxacin and ofloxacin. There was no mortality. Conclusions: Enteric fever should be suspected in all the children with fever for more than five days along with anorexia, gastrointestinal associated symptoms and normal white blood counts.

scholarly journals THE EPIDEMIOLOGICAL PROFILE OF COVID-19 PATIENTS

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Sangeeta Gahlot ◽  
Surendra Yadav ◽  
Makkhan Lal Saini
Keyword(s):  
Medical Records ◽  
Severe Disease ◽  
Treatment Options ◽  
Age Groups ◽  
Signs And Symptoms ◽  
Medical Attention ◽  
Laboratory Findings ◽  
Asymptomatic Patients ◽  
The Mean ◽  
Epidemiological Profile

Background: In this study, epidemiological profiles of COVID-19 patients who have visited the hospital have been evaluated. Methods: We collected data of 100 patients from their medical records. These data included age, sex, comorbidities, levels of illness severity (mild, moderate, severe, and asymptomatic), signs and symptoms, treatment options, laboratory findings, and computed tomography (CT) images Results: The mean age were 61.23±12.36 years with age groups ranging from 17 to 85 years. Men were 69; M:F ratio being 2.26:1. There were 76 symptomatic and 24 asymptomatic patients. Mortality was higher in symptomatic patients. Conclusion: Patients aged more than 60 years are more prone for severe disease with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pneumonia and this subset of patients requires urgent medical attention. Keywords: Age, Sex, COVID-19.

scholarly journals Profile of COVID-19 Patients in Dr. Moewardi Hospital Surakarta Indonesia

2021 ◽  
Vol 9 (B) ◽  
pp. 1621-1624
Author(s):  
Cahyono Hadi ◽  
Cipta Pramana
Keyword(s):  
Cardiovascular Disease ◽  
Medical Records ◽  
Descriptive Study ◽  
Age Group ◽  
Cytokine Analysis ◽  
Tnf Α ◽  
Average Patient ◽  
The Mean ◽  
Male Sex ◽  
Age Range

BACKGROUND: The 2019 coronavirus disease has been declared by WHO as a pandemic that has spread throughout the world since March 2020. AIM: This study was conducted to determine the profile of COVID-19 patients at Dr. Moewardi hospital Surakarta. METHODS: This study is a retrospective descriptive study, with the population and study samples taken from medical records of patients with a diagnosis of COVID-19 or SARS-CoV-2. RESULTS: male sex with a total of 42 patients (47.72%) and female sex 46 patients (52.57%). The highest age group was in the age group 40-59 years with 46 patients (52.27%), with the most comorbid history being cardiovascular disease 31 patients (35.22%). The mean cytokine analysis of 88 patients includes examination of IL-1 that is equal to 73.95 and TNF-α with a mean of 67.19. The mean shows an increase above the normal value. CONCLUSION: There is no difference between the sexes of men and women. The highest age range is in the 40-59-year age group. The most common comorbid history is cardiovascular disease. And the average patient showed increased levels of IL-1 and TNF-α.

scholarly journals Pediatrics Infected with COVID-19: A Case Series Study on Pediatrics Hospitalized in a Referral Pediatric Hospital

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Houman Hashemian ◽  
Saeid Sadat Mansouri ◽  
Hamid Reza Badeli ◽  
Ebrahim Esmaili ◽  
Majid Asgharzadeh ◽  
...  
Keyword(s):  
Ct Scan ◽  
Clinical Laboratory ◽  
Treatment Strategies ◽  
Case Series ◽  
Pediatric Hospital ◽  
Laboratory Findings ◽  
Case Series Study ◽  
The Mean ◽  
Underlying Diseases ◽  
Series Study

Introduction. COVID-19 infection which is a novel pneumonia associated with coronavirus suddenly broke out in the world. The aim of this study is to analyze and summarize the clinical characteristics of pediatric patients who were hospitalized in a referral pediatric hospital because of COVID-19 infection. Materials and Methods. Twenty-one COVID-19 infection cases confirmed by clinical and laboratory findings who were hospitalized in our center from 20 February to 19 April 2020 were included. Demography information, clinical, laboratory, and radiological findings, and treatment strategies of patients were evaluated. Results. The mean age was 91.5 ± 68.38 months (1-225), and there were 12 (57.1%) boys and 9 (42.9%) girls. Fever ≥ 38 ° C was detected in 11 (52.4%) patients. Eleven (52.3%) patients had tachypnea, and 4 (19%) of them developed tachycardia. Nine CT scans (42.85%) demonstrated a halo sign, and patchy infiltration was seen in CT scan of 7 patients (33.33%). Furthermore, bilateral crazy-paving pattern was seen in CT scan of nine (42.85%) patients. We prescribed chloroquine in 8 (38.1%), oseltamivir in 8 (38.1%), Kaletra in 6 (28.6%), and Ribavirin in 1 (4.8%) of patients. Finally, four (19.04%) patients expired which one of them suffered from ARDS. Conclusions. We found out that boys might develop more severe cases of COVID-19, and this could be more common in school age. Manifestations might be milder than adults, and the most severe cases might be associated with underlying diseases. Also, the effectiveness of drugs in the treatment of this disease needs further study.

scholarly journals The Effect of the COVID-19 Pandemic on BMI in Children and Adolescents: A Retrospective Cohort Study

2021 ◽  
Author(s):  
Arwa Nasir ◽  
Robin High ◽  
Laeth Nasir
Keyword(s):  
Cohort Study ◽  
Children And Adolescents ◽  
Retrospective Cohort Study ◽  
Mixed Models ◽  
Medical Records ◽  
Retrospective Cohort ◽  
Study Data ◽  
Overweight And Obesity ◽  
The Mean ◽  
Percentile Point

Abstract Background:The COVID-19 pandemic created circumstances with the potential to increase rates of overweight and obesity. We aimed to assess whether there were significant increases in BMI among a sample of children and adolescents during the year 2020compared to the two years prior to the pandemic. Methods:For this retrospective cohort study, data was obtained from the electronic medical records of 8398 children 3-17 years of age who attended3 consecutive well visits between June 1 and October 31 in 2018, 2019 and 2020 in a single center in the Midwest. Generalized linear mixed models were used to calculate the differences in average BMI and obesityrates over the three years.Results:Between 2019 and 2020, the mean BMI for the whole sample increased 3.2 percentile points (from the 70·5th to the 73·7th percentile; p<0·001)compared to an increase of 0.8 percentile point between 2018 and 2019 (p=0·008). The proportion of children and adolescents with obesity rose from 13% in 2019 to 15·2% in 2020 (p<0·001) compared to no significant increasefrom 2018 to 2019. Significant disparities in BMI were observed between socioeconomic and ethnic groups.ConclusionsSignificant increases in BMI and obesity rates occurred in 2020 in this sample. We propose that the circumstances surrounding the COVID-19 pandemic contributed significantly to these increases.

scholarly journals Assessment of mortality in correlation with comorbidities in COVID-19 patients of Telangana state.

2020 ◽  
Author(s):  
Rajarao Mesipogu ◽  
Vinayasekhar Adeula ◽  
Thrilok Chander Bingi ◽  
Nagamani Kammili ◽  
Madhavilatha Manolla ◽  
...  
Keyword(s):  
Clinical History ◽  
Mortality Data ◽  
Comorbid Conditions ◽  
Elderly Male ◽  
Laboratory Findings ◽  
The Mean ◽  
Age Range ◽  
Epidemiological Characteristics ◽  
Death Cases ◽  
Age Of Death

Abstract Background The mortality data of COVID cases around the world has less explored in relation to comorbidities.The dogma/question to be answered is that the virus perse resulting or any comorbidities contributing to such frightened deaths.The aim of the study is to describe the clinical and epidemiological characteristics of 201 deceased from Telangana. We retrospectively collected all consecutive death cases with laboratory‐confirmed COVID‐19 infection admitted from March to mid-June at Gandhi Hospital the nodal centre designated for COVID-19 in Telangana. Clinical history, comorbidities, laboratory findings and treatment were recorded for each patient.Results A total of 15394 patients with confirmed COVID‐19 test were admitted at Isolation wards between March 2020 and June 2020 and 253 death cases were reported till the submission of this paper. The mean age of death is 57.0 ys in our study, 40.7% (88) deaths were above 60 years and 71.4% (147) were male. Several comorbid conditions existed with COVID-19 death cases among which hypertension being the most common comorbidity (60.1%). Lymphopenia was observed in 46% cases while lymphopenia with comorbidity was recorded in 63% cases.Conclusion In this retrospective study, most of the COVID‐19 deceased patients were elderly male aged with an age range from 50-60 yrs and above. Mortality rate and severity are higher in males than females. Our study indicated the importance of understanding comorbid conditions in COVID‐19 cases especially Hypertension and Diabetes mellitus as they were more likely succumb to death.

scholarly journals Midfoot Arthritis in Children: Is There Any Relation With Malignancy?

2020 ◽  
Vol 13 ◽  
pp. 117954412092464
Author(s):  
Reza Shiari ◽  
Nargess Salar ◽  
Vadood Javadi Parvneh ◽  
Khosro Rahmani ◽  
Mehrnoush Hassas Yeganeh ◽  
...  
Keyword(s):  
Medical Records ◽  
Lymphoblastic Leukemia ◽  
Laboratory Data ◽  
Cross Sectional Study ◽  
Musculoskeletal Symptoms ◽  
Cell Precursor ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Significant Difference ◽  
Leukemia In Children

Background: Musculoskeletal symptoms are a presenting manifestation in a number of lymphoproliferative disorders including leukemia, especially in children. Among these primary symptoms, midfoot arthritis seems to be an important alarm for malignancy in children. The aim of this study is evaluation association of midfoot arthritis with malignancy in children. Method: In this cross-sectional study, all medical records of patients with arthritis were identified and reviewed. All clinical and laboratory data were recorded in the information form and data were analyzed by SPSS 25 software. Results: A total of 557 cases of arthritis were evaluated, of which 18 (3.2%) cases have primary symptoms of midfoot arthritis. Four of 18 patients (22.2%) had B-cell precursor acute lymphoblastic leukemia, that midfoot arthritis was their first manifestation. Also, their laboratory findings confirmed that platelet, lactic acid dehydrogenesis, and uric acid values were significantly higher in these children. Based on statistical evaluation, there was no significant difference between age and sex in these patients. Conclusion: According to the findings of the present study, it can be concluded that “midfoot arthritis” may be the first manifestation of leukemia in children even with a near-normal hematologic values.

scholarly journals Frequency of polypharmacy and drug interactions in inpatients in the emergency department, Southwest of Iran

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Mobina Tahmasebivand ◽  
Hassan Barzegari ◽  
Mandana Izadpanah
Keyword(s):  
Emergency Department ◽  
Standard Deviation ◽  
Drug Interactions ◽  
Medical Records ◽  
Study Data ◽  
Study Population ◽  
The Mean ◽  
Southwest Of Iran ◽  
Drug Therapy Problems ◽  
Length Of Hospitalization

This study aimed to evaluate the polypharmacy extent and the frequency and severity of drug interactions by evaluating inpatients in the emergency department. In this epidemiologicaldescriptive study, data were collected retrospectively by reviewing medical records of 92 hospitalized patients in the emergency department with a stay over 48 hours. Out of the study population, 54.3% and 45.7% were respectively male and female, with a mean age of 59.09. In terms of hospitalization, 27.2% and 16.3% were hospitalized due to heart problems and trauma, respectively and the mean length of hospitalization was 3.91 with a standard deviation of 2.57 days. The mean drug received was 8.48, with a standard deviation of 4.48. Of the patients, 81.5% received more than 5 drugs; in addition, the observed amounts of drug interactions of A, B, C, D, and X were 2.5%, 17%, 59.3%, 19.5%, and 1.9%, respectively. The drug interaction prevalence in inpatients in the emergency department was high. The presence of a pharmacist is necessary to identify drug interactions and reduce drug-therapy problems to provide quality services.

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