scholarly journals Comorbidities and Health-Related Quality of Life in Subjects with Spine Osteoarthritis at 50 Years of Age or Older: Data from the Korea National Health and Nutrition Examination Survey

Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 126
Author(s):  
Seong-Kyu Kim ◽  
Jung-Yoon Choe

Background and Objective: This study assessed comorbidities and health-related quality of life (HRQOL) in subjects with lumbar spine osteoarthritis (OA) in the Korean population. Materials and Methods: We analyzed 3256 subjects who were 50 years or older and underwent plain radiography of the lumbar spine as part of the Korea National Health and Nutrition Examination Survey (KNHANES) 2012. Radiographic assessment was based on Kellgren–Lawrence (K-L) grade ranging from 0 to 2, with K-L grade 2 defined as lumbar spine OA. HRQOL was assessed by EuroQol-5 dimensions (EQ-5D), which include the EQ-5D index and visual analogue scale (EQ-VAS) measurements. Results: Comorbidities such as hypertension, myocardial infarction, angina, cerebral infarction, and diabetes mellitus were more frequent in spine OA than in controls, while dyslipidemia was less common. Subjects with spine OA had higher mean number of comorbid conditions than controls (1.40 (SE 0.05) vs. 1.20 (SE 0.03), p = 0.001). Subjects with spine OA had much lower EQ-5D index than controls (p < 0.001) but not lower EQ-VAS score. Multivariate binary logistic analysis showed that hypertension and colon cancer were associated with spine OA compared to controls (OR 1.219, 95% CI 1.020–1.456, p = 0.030 and OR 0.200, 95% CI 0.079–0.505, p = 0.001, respectively) after adjustment for confounding factors. Lower EQ-5D index was related to spine OA (95% CI 0.256, 95% CI 0.110–0.595, p = 0.002) but not EQ-VAS score. Conclusion: In this study, we found that comorbidities such as hypertension and colon cancer as well as lower HRQOL were associated with spine OA.

2020 ◽  
Author(s):  
Kil-Yong Jeong ◽  
Hyun Jung Lee

Abstract Background: The purpose of this study was to analyze the risk factors affecting the prevalence of osteoarthritis and the health-related quality of life (HRQoL) of stroke patients from various angles, including demographic factors, socioeconomic factors, comorbidities, and lifestyle factors.Methods: A total of 13,959 patients ≥40 years of age (stroke group n = 416, non-stroke group n = 13,535) were identified from the 2016–2018 Korean National Health and Nutrition Examination Survey for analysis. The European quality of life-5 dimensions questionnaire was used to compare the differences in stroke patient’s HRQoL according to the presence or absence of osteoarthritis. Multiple regression analysis was performed to determine the factors affecting the HRQoL of the stroke group.Results: The prevalence of osteoarthritis was 21.72% in the stroke group and 12.49% in the non-stroke group. The prevalence of osteoarthritis in female patients who had strokes was 35.95% and was significantly higher than that of male patients who had strokes (10.23%). The European quality of life-5 dimensions index indicating HRQoL was significantly lower in stroke group with osteoarthritis. Factors that significantly influenced the HRQoL in the stroke group were the presence of osteoarthritis, aerobic exercise, drinking status, types of health insurance, and educational levels.Conclusions: This study confirmed that the HRQoL was significantly lower in stroke group with osteoarthritis. Findings were taken to suggest that the active management of osteoarthritis in stroke patients are important.


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