scholarly journals Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants

Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 133
Author(s):  
Domenico M. Romeo ◽  
Martina Ricci ◽  
Federica Mirra ◽  
Ilaria Venezia ◽  
Maria Mallardi ◽  
...  

Background and Objectives: Preterm infants are at higher risk of neurodevelopmental impairment both at preschool and school ages, even in the absence of major neurological deficits. The early identification of children at risk is essential for early intervention with rehabilitation to optimize potential outcomes during school years. The aim of our study is to assess cognitive outcomes at preschool age in a cohort of low-risk very preterm infants, previously studied at 12 and 24 months using the Griffiths scales. Materials and Methods: Sixty-six low-risk very preterm infants born at a gestational age of <32 weeks were assessed at 12 and 24 months corrected age using the Griffiths Mental Development Scales (second edition) and at preschool age with the Wechsler Preschool and Primary Scales of Intelligence (third edition) (WPPSI-III). Results: At 12 and 24 months and at preschool age, low-risk very preterm infants showed scores within normal ranges with similar scores in males and females. A statistically significant correlation was observed in the general developmental quotient between 12 and 24 months; a further significant correlation was observed between the early cognitive assessments and those performed at preschool age, with a better correlation using the assessments at 24 months. Conclusion: The present study showed a favourable trajectory of cognitive development in low-risk very preterm infants, from 12 months to preschool age.

2019 ◽  
Vol 61 (4) ◽  
pp. 381-387 ◽  
Author(s):  
Friedrich Reiterer ◽  
Anna Scheuchenegger ◽  
Bernhard Resch ◽  
Ute Maurer‐Fellbaum ◽  
Alexander Avian ◽  
...  

2018 ◽  
Vol 127 ◽  
pp. 74-84 ◽  
Author(s):  
Annice H.T. Kong ◽  
Melissa M. Lai ◽  
Simon Finnigan ◽  
Robert S. Ware ◽  
Roslyn N. Boyd ◽  
...  

1989 ◽  
Vol 246 (2) ◽  
pp. 91-96 ◽  
Author(s):  
J. Dietl ◽  
H. Arnold ◽  
H. Mentzel ◽  
H. A. Hirsch

PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0168162 ◽  
Author(s):  
Anna Posod ◽  
Irena Odri Komazec ◽  
Katrin Kager ◽  
Ulrike Pupp Peglow ◽  
Elke Griesmaier ◽  
...  

2020 ◽  
Vol 25 (Supplement_2) ◽  
pp. e17-e18
Author(s):  
Lindsay McRae ◽  
Emily Kieran ◽  
Thuy Mai Luu ◽  
Sandesh Shivananda ◽  
Anne Synnes

Abstract Introduction/Background Bronchopulmonary dysplasia (BPD) is a common complication of extreme prematurity and may require prolonged home respiratory support. BPD is associated with worse neurodevelopmental outcomes but the impact of home respiratory support on neurodevelopmental outcomes, rehospitalization rates and association with caregiver sociodemographics is less well studied. Objectives This study examines the impact of home respiratory support on neurodevelopmental outcomes in very preterm infants at 18-24 months corrected gestational age. Design/Methods This linked Canadian Neonatal Network and Canadian Neonatal Follow-Up Network (CNFUN) multicenter cohort study of infants born April 1, 2009-December 31, 2016 at &lt;29 weeks’ gestational age assessed at 18-24 months corrected age at a CNFUN site compared significant neurodevelopmental impairment rates, rehospitalization rates and sociodemographics in children with and without home respiratory support using Chi-square and student t-tests. Results Of the 3918 infants, 622 (15.9%) received home respiratory support. As expected, infants on home respiratory support had a lower gestational age (mean 25.5 vs 26.5 weeks, p &lt; 0.01), lower birth weight (mean 781 vs 955 grams, p &lt; 0.01), longer NICU stay (mean 118 vs 76 days, p &lt; 0.01) and more comorbidities: late onset sepsis (35.1% vs 22.9%, p &lt; 0.01), NEC ≥ stage 2 (8.9% vs 5.9%, p = 0.01), grade 3-4 IVH or PVL (12.7% vs 8.4%, p &lt; 0.01) and ROP ≥ grade 3 (28% vs 10.8%, p &lt; 0.01). Infants on home respiratory support had higher significant neurodevelopmental impairment rates defined as Bayley-III motor, cognitive, language scores &lt;70, nonambulatory cerebral palsy (GMFCS ≥ 3), hearing and/or visual impairment rates (Table 1), rehospitalization rates (63.3% vs 29.2%, p &lt; 0.01) and &gt;3 rehospitalizations (19.8% vs 5.0%, p &lt; 0.01). With home respiratory support, fewer families had paid employment and more were on social welfare. Conclusion Children born preterm who are discharged home on respiratory support, compared to those without home support, are more likely to experience neurodevelopmental impairment and rehospitalization, and may have an adverse impact on family income. This is important for discharge planning and follow-up care of these high risk children.


2017 ◽  
Vol 81 (5) ◽  
pp. 787-794 ◽  
Author(s):  
Anna Posod ◽  
Susanne Müller ◽  
Irena Odri Komazec ◽  
Daniel Dejaco ◽  
Ulrike Pupp Peglow ◽  
...  

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