scholarly journals Metabolomics Study of Flavonoids of Taxilluschinensis on Different Hosts Using UPLC-ESI-MS/MS

Molecules ◽  
2021 ◽  
Vol 26 (24) ◽  
pp. 7681
Author(s):  
Li Li ◽  
Jianbei Teng ◽  
Yilin Zhu ◽  
Fengfeng Xie ◽  
Jing Hou ◽  
...  
Keyword(s):  
Host Plant ◽  
Parasitic Plants ◽  
Morus Alba ◽  
Total Flavonoids ◽  
Tandem Mass ◽  
Anti Cancer ◽  
Metabolomics Study ◽  
Sample Correlation ◽  
Total Flavonoids Content ◽  
White Mulberry

The goal of this study was to identify and compare the main biomarkers of Taxillus chinensis from different hosts. A metabolomics approach utilizing ultra-pressure liquid chromatography coupled with tandem mass spectrometry (UPLC-MS), including cluster analysis, sample correlation analysis and orthogonal partial least squares discriminant analysis, was used to explore the flavonoid metabolites of Taxillus chinensis growing on different hosts. Results: The total flavonoids content (up to 30.08 mg/g) in Taxillus chinensis from Morus alba (CSG) was significantly higher than that from growth on Liquidambar formosana (CFG) or Clausena lansium (CHG) (p < 0.01). There were 23 different metabolites between CSG and CHG, 23 different metabolites between CSG and CFG, and 19 different metabolites between CHG and CFG. The results demonstrated that different hosts exerted a large influence on the metabolites of Taxillus chinensis; it was found that CSG differed from CFG and CHG in eleven metabolic compounds, ten of which were upregulated and one of which was downregulated. Most of these metabolites derive from compounds contained in the host plant, white mulberry (Morus alba); many feature potent anti-cancer effects. Differences in host can influence the type and abundance of flavonoids in parasitic plants such as Taxillus chinensis, which is of great significance to researchers seeking to understand the formation mechanism of Taxillus chinensis metabolites. Therefore, attention should be paid to the species of host plant when studying the Taxillus chinensis metabolome. Plants grown on Morus alba offer the greatest potential for the development of new anti-cancer drugs.

An Overview on Phytochemical and Pharmacological Profile of Morus alba Linn.

2020 ◽  
Vol 16 ◽  
Author(s):  
Arpita Paul ◽  
Monami Rajiung ◽  
Kamaruz Zaman ◽  
Sushil Kumar Chaudhary ◽  
Hans Raj Bhat ◽  
...  
Keyword(s):  
Traditional Medicine ◽  
Morus Alba ◽  
Biologically Active ◽  
Pharmacological Profile ◽  
Pharmacological Activities ◽  
Significant Information ◽  
The Past ◽  
Comprehensive Information ◽  
The Family ◽  
White Mulberry

Background: Morus alba Linn. commonly known as white mulberry, belongs to the family Moraceae, is a promising traditional medicine. In Asia, besides its use in the preparation of delicacies, every part of this plant is utilized in traditional medicine. Over the past decade, studies related to identification and isolation of biologically active compounds, with flavonoids as the major class of phytoconstituents, from this plant has been reported. These phytoconstituents are not only found to be beneficial for the maintenance of general health but also are associated with a range of potential pharmacological activities such as antioxidant, anti-inflammatory, anti-diabetic, anticancer, hepatoprotective, cardioprotective, neuroprotective to name a few. Objective: This review aims to provide upgraded and comprehensive information regarding the phytochemical, ethnomedicinal use and pharmacological profile of the plant Morus alba Linn. Method: The significant information has been collected through various database viz. PubMed, Scopus, Web of Science, Science Direct based on the recent findings, using different terms of Morus alba. Results: The outcome of the study suggests that Morus alba is a multifunctional plant numerous phytochemicals, and possess a range of pharmacological activities. Conclusion: The data assembled on Morus alba will be beneficial to trigger research in various fields of pharmaceutical and allied science to explore the medicinal importance of this unique plant.

scholarly journals Optimization of Supercritical Extraction Conditions of Senna Alata and Evaluation of Biological Activity

2018 ◽  
Vol 7 (3.11) ◽  
pp. 94
Author(s):  
Istikamah Subuki ◽  
Aiman Nabilah Abdul Malek ◽  
Saidatul Husni Saidin ◽  
Mazura Md. Pisar
Keyword(s):  
Crude Extract ◽  
Extraction Process ◽  
Quadratic Model ◽  
Total Flavonoids ◽  
Inhibition Activity ◽  
Backward Elimination ◽  
Total Flavonoids Content ◽  
Senna Alata ◽  
Central Composite ◽  
Experimental Runs

Supercritical fluid extraction (SFE) offer faster extraction process, decreased solvent usage and more selectivity on desired compounds. In this present study, the influence of pressure (100, 200 and 300 bar) and temperature (40, 50 and 60˚C) on the Senna alata crude yield were investigated with fixed supercritical carbon dioxide (SC-CO2) at the flow rate of 35 g/min. The parameters were optimised and modelled using response surface methodology (RSM) and central composite design (CCD). The analysis of variance (ANOVA) experimental design consists of 13 experimental runs with 5 replicates at the central points. Well-fitting quadratic model were successfully established for crude extract through backward elimination. The optimum crude extract yield pointed out by RSM was at the pressure of 300 bar and temperature 40˚C respectively. Extraction yields based on SC-CO2 varied in the range of 0.28 to 3.62%. The highest hyaluronidase inhibition activity and total flavonoids content obtained by S.alata crude extracts were 41.19% and 52.53% w/w, respectively. SC-CO2 proves to have great potential for extraction of yield, hyaluronidase inhibition activity and total flavonoids content for S.alata.  

Structures, bioactivities and future prospective of polysaccharides from Morus alba (white mulberry): A review

2018 ◽  
Vol 245 ◽  
pp. 899-910 ◽  
Author(s):  
Xirui He ◽  
Jiacheng Fang ◽  
Yinlan Ruan ◽  
Xiaoxiao Wang ◽  
Yin Sun ◽  
...  
Keyword(s):  
Morus Alba ◽  
White Mulberry

scholarly journals Relationships between flavonoids and selected elements in infusions of medicinal herbs

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Pawel Konieczynski ◽  
Agnieszka Arceusz ◽  
Marek Wesolowski
Keyword(s):  
Principal Component Analysis ◽  
Principal Component ◽  
Total Content ◽  
Essential Elements ◽  
Medicinal Herbs ◽  
Total Flavonoids ◽  
Aqueous Extracts ◽  
Zn And Cu In ◽  
Total Flavonoids Content ◽  
The Mean

AbstractThe aim of the studies was to establish relationships between flavonoids and elements important for human health. Therefore, total contents of flavonoids and phosphorus were determined by UV/Vis methods, flavonoids by HPLC, and Ca, Mg, Fe, Mn, Zn and Cu by FAAS in 68 infusions of medicinal herbs. Total flavonoids content in the aqueous extracts were in the range of 0.26 - 16.40 mg per 100 mL. The mean flavonoid contents (in mg per 100 mL of aqueous extract) were 2.24, 2.01, 1.83, 1.88 for rutin, myricetin, quercetin and kaempferol, respectively. The concentrations of Ca, Mg, P were determined in mg per 100 mL, and of Fe, Mn, Zn and Cu in μg per 100 mL. Total content of flavonoids was weakly correlated with quercetin (r = 0.41), kaempferol (r = 0.53), Cu (r = 0.43), and Ca (r = -0.30). Statistically significant correlations were also found among Cu, Ca, Mn, Zn and Fe. Cluster analysis grouped the studied herbs based on total flavonoids, also four flavonoids and essential elements contents, extracted from the whole population of herbs Sambuci flos, Betulae folium, and Sylibi mariani semen. Principal component analysis confirmed these findings and enabled identification of quercetin, kaempferol, Cu and Fe as the factors responsible for differentiation of the studied material.

scholarly journals Comparative study of different drying methods regard to the phenols and flavonoids content of dried Citrus aurantium L. leaves

2021 ◽  
Author(s):  
Geovanni Hernandez Galvez ◽  
Margarita Castillo Téllez ◽  
Jorge de Jesús Chan González ◽  
Francisca Méndez Morales ◽  
Damianys Almenares López ◽  
...  
Keyword(s):  
Natural Convection ◽  
Forced Convection ◽  
Design Methodology ◽  
Total Phenol ◽  
Drying Methods ◽  
Total Flavonoids ◽  
Citrus Aurantium ◽  
Solar Drying ◽  
Solar Dryer ◽  
Total Flavonoids Content

Objective: To determine the effects of different thermal drying technologies on the total phenol and flavonoid contents (TPC) and total flavonoids (TFC) in sour orange (Citrus aurantium L.) leaves. Design/methodology/approach: Solar drying was carried out in outdoor sunny conditions using two direct solar dryers; one with natural convection, the other with forced convection. The total phenol and flavonoid contents in gallic acid equivalents (GAE) and quercetin (Q), respectively, of ethanolic extracts of C. aurantium were assessed with spectrophotometric techniques. Results: The results demonstrated maximum phenol values for the direct natural convection solar dryer (161.4 mg EAG/g MS) and minimum values for shade drying (61.43 mg EAG/g MS). As for flavonoids, the highest values were obtained in the direct forced convection solar dryer (32.22 ± 1.6 mg EQ/g MS), while the lowest was registered in the open air sun (11.72 mg EQ/g MS). Conclusions: Direct solar dryers are technologies effective for maintaining the phenols and total flavonoids content in dried leaves of C. aurantium.  

scholarly journals The Effect of Salicylic Acid on Response to Water Deficit in Basil

2018 ◽  
Vol 2 (1) ◽  
pp. 42
Author(s):  
Adisa Paric ◽  
Erna Karalija
Keyword(s):  
Salicylic Acid ◽  
Photosynthetic Pigments ◽  
Peroxidase Activity ◽  
Total Phenolics ◽  
Stem Length ◽  
Limiting Factor ◽  
Total Flavonoids ◽  
Induced Stress ◽  
Total Flavonoids Content ◽  
Response To Water

Drought-induced stress is the main limiting factor that affects growth and development in plants. In this study, the effect of exogenous application of salicylic acid (SA) on drought tolerance in basil was investigated. The analysis showed that application of SA under drought stress had significant effects on physiological and biochemical parameters, such as photosynthetic pigments content, total phenolics, flavonoids, flavanols and protein content and peroxidise activity, but had no significant effects on the morphological parameters, such as stem length, length and areaof leaves . In drought conditions, total phenolics and peroxidase activity reduced significantly, but all photosynthetic pigments, total flavonoids, flavanols and proteins increased significantly. Application of SA displayed some alleviating effects against drought induced stress through increase of plant growth, total flavonoids content and peroxidase activity

scholarly journals Air-drying temperature changes the content of the phenolic acids and flavonols in white mulberry (Morus alba L.) leaves

2019 ◽  
Vol 49 (11) ◽  
Author(s):  
Monika Przeor ◽  
Ewa Flaczyk ◽  
Monika Beszterda ◽  
Krystyna Eleonora Szymandera-Buszka ◽  
Justyna Piechocka ◽  
...  
Keyword(s):  
Phenolic Acids ◽  
Phenolic Acid ◽  
Total Content ◽  
Morus Alba ◽  
Air Drying ◽  
Drying Temperature ◽  
Temperature Changes ◽  
Mulberry Leaves ◽  
White Mulberry ◽  
New Compounds

ABSTRACT: The white mulberry leaves are typically available on the market in dried or encapsulated form. It was assumed in the study that appropriate drying of leaves of the white mulberry is significant for obtaining intermediate products with high content of compounds having anti-oxidative activity. The purpose of the study was to determine the influence of the temperature of mulberry leaves air drying on the content of phenolic acids and flavonols. It has been determined that the content of these compounds in the leaves depended on the drying temperature. Drying at 60 °C favored release of phenolic acids and flavonols from complexes and/or formation of new compounds. Their total content was 22% higher than in leaves dried at 30 °C. Drying at 90 °C reduced the phenolic acid and flavonol content by 24%. The most favorable drying temperature was 60 °C.

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