scholarly journals The Optimization of Extraction Process, Antioxidant, Whitening and Antibacterial Effects of Fengdan Peony Flavonoids

Molecules ◽  
2022 ◽  
Vol 27 (2) ◽  
pp. 506
Author(s):  
Jie Lu ◽  
Zhiqiang Huang ◽  
Yusheng Liu ◽  
Huimin Wang ◽  
Min Qiu ◽  
...  
Keyword(s):  
Free Radical ◽  
Functional Food ◽  
Biological Activities ◽  
Extraction Process ◽  
Dry Mass ◽  
Raw Material ◽  
Seed Meal ◽  
Total Flavonoids ◽  
Minimal Inhibitory Concentrations ◽  
Great Possibility

Flavonoids have important biological activities, such as anti-inflammatory, antibacterial, antioxidant and whitening, which is a potential functional food raw material. However, the biological activity of Fengdan peony flavonoid is not particularly clear. Therefore, in this study, the peony flavonoid was extracted from Fengdan peony seed meal, and the antioxidant, antibacterial and whitening activities of the peony flavonoid were explored. The optimal extraction conditions were methanol concentration of 90%, solid-to-liquid ratio of 1:35 g:mL, temperature of 55 °C and time of 80 min; under these conditions, the yield of Fengdan peony flavonoid could reach 1.205 ± 0.019% (the ratio of the dry mass of rutin to the dry mass of peony seed meal). The clearance of Fengdan peony total flavonoids to 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical, hydroxyl radical and 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) free radical could reach 75%, 70% and 97%, respectively. Fengdan peony flavonoid could inhibit the growth of the Gram-positive bacteria. The minimal inhibitory concentrations (MICs) of Fengdan peony flavonoid on S. aureus, B. anthracis, B. subtilis and C. perfringens were 0.0293 mg/mL, 0.1172 mg/mL, 0.2344 mg/mL and 7.500 mg/mL, respectively. The inhibition rate of Fengdan peony flavonoid on tyrosinase was 8.53–81.08%. This study intensely illustrated that the antioxidant, whitening and antibacterial activity of Fengdan peony total flavonoids were significant. Fengdan peony total flavonoids have a great possibility of being used as functional food materials.

scholarly journals A green extraction design for enhancing flavonoid compounds from Ixora javanica flowers using a deep eutectic solvent

2020 ◽  
Vol 7 (10) ◽  
pp. 201116
Author(s):  
Nina Dewi Oktaviyanti ◽  
Kartini Kartini ◽  
Mochammad Arbi Hadiyat ◽  
Ellen Rachmawati ◽  
Andre Chandra Wijaya ◽  
...  
Keyword(s):  
Extraction Method ◽  
Choline Chloride ◽  
Deep Eutectic Solvent ◽  
Extraction Process ◽  
Raw Material ◽  
Molar Ratio ◽  
Flavonoid Compound ◽  
Total Flavonoids ◽  
Green Extraction ◽  
Optimum Extraction

In this study, an environmentally friendly extraction method for flavonoid compound from Ixora javanica , as a new raw material candidate for herbal medicine and cosmetics, was developed. The objectives of the present work were to provide recommendations for the optimal extraction conditions and to investigate the effects of any extraction parameters on flavonoid yields from the I. javanica flower. The extraction process was performed using deep eutectic solvent (DES) (choline chloride and propylene glycol at molar ratio of 1 : 1) and the ultrasound-assisted extraction method. Both single-factor and response surface analyses using three-level and three-factor Box Behnken designs were conducted to obtain the optimum flavonoid concentrations. The results showed that the optimum extraction conditions for total flavonoids featured an extraction time of 40 min, 25% water content in DES and a solid-to-liquid ratio of 1 : 25 g ml −1 . An extract obtained under optimum extraction conditions showed higher total flavonoid yields than an ethanolic extract which was used for comparison. Scanning electron microscope images demonstrated that both of the solvents also showed different effects on the outer surface of the I. javanica flower during the extraction process. In summary, our work succeeded in determining the optimum conditions for total flavonoids in the I. javanica flower using a green extraction method.

scholarly journals Anti-Oxidant and Anti-Enzymatic Activities of Sea Buckthorn (Hippophaë rhamnoides L.) Fruits Modulated by Chemical Components

Antioxidants ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 618 ◽  
Author(s):  
Karolina Tkacz ◽  
Aneta Wojdyło ◽  
Igor Piotr Turkiewicz ◽  
Łukasz Bobak ◽  
Paulina Nowicka
Keyword(s):  
Biological Activities ◽  
Dry Mass ◽  
Sea Buckthorn ◽  
Hippophae Rhamnoides ◽  
Raw Material ◽  
Chemical Components ◽  
High Biological Activity ◽  
Hippophaë Rhamnoides ◽  
Anti Oxidant

The aim of this study was to analyze in vitro biological activities as anti-oxidant, anti-α-amylase, anti-α-glucosidase, anti-lipase, and anti-lipoxygenase activity, relative to bioactive components (phenolic acids, flavonols, xanthophylls, carotenes, esterified carotenoids, tocopherols, tocotrienols, and fatty acids) and the basic chemical composition (sugars, organic acid, dry matter, soluble solid, pH, titratable acidity, ash, pectins, and vitamin C) of Hippophaë rhamnoides berries. Six sea buckthorn cultivars commonly grown in Poland were analyzed including Aromatnaja, Botaniczeskaja-Lubitelskaja, Józef, Luczistaja, Moskwiczka, and Podarok Sadu. Berries contained 1.34–2.87 g of sugars and 0.96–4.22 g of organic acids in 100 g fresh weight, 468.60–901.11 mg of phenolic compounds, and 46.61–508.57 mg of carotenoids in 100 g dry mass. The fatty acid profile was established: palmitic > palmitoleic > oleic and linoleic > stearic and linolenic acids. The highest anti-oxidant (34.68 mmol Trolox/100 g dry mass) and anti-α-amylase potential (IC50 = 26.83 mg/mL) was determined in Aromatnaja, anti-α-glucosidase in Botaniczeskaja-Lubitelskaja (IC50 = 41.78 mg/mL), anti-lipase in Moskwiczka and Aromatnaja (average IC50 = 4.37 mg/mL), and anti-lipoxygenase in Aromatnaja and Podarok Sadu fruits (100% inhibition). The studied sea buckthorn berries may be a raw material for the development of functional foods and nutraceutical products rich in compounds with high biological activity.

scholarly journals Extraction Process and Analysis of Components in Essential Oils of Piper longum Linn. Harvested in Dak Lak Province, Vietnam

2020 ◽  
Vol 32 (10) ◽  
pp. 2639-2646
Author(s):  
Thien Hien Tran ◽  
Van Chi Khang ◽  
Hoang Duy Ngo ◽  
Xuan Tien Le
Keyword(s):  
Essential Oil ◽  
Biological Activities ◽  
Survey Methods ◽  
Antibacterial Properties ◽  
Extraction Process ◽  
Raw Material ◽  
Gas Chromatography Mass Spectrometry ◽  
Piper Longum ◽  
Lack Of Fit ◽  
Essential Oil Yield

Nowadays, plants containing biological activities are increasingly interested for their antioxidant and antibacterial properties. In particular, Pepper longum Linn. was known as one of the popular types of pepper family in Vietnam with many different uses in food and medicine. In this study, Pepper longum fruits were studied for extraction to essential oil by hydrodistillation through two survey methods such as single factor investigation method and optimization by response surface methodology (RSM). The analysis results by design expert software program version 11 shown that at the condition that the ratio of water to raw material 6:1 (mL/g), during 225 min extraction at 130 ºC, the essential oil yield was obtained 0.8%. The model predicts this result for F-value, P-values and Lack of Fit are mathematically significant and values for reliability R2 = 0.9963, C.V. % =1.99. Essential oil obtained was evaluated by gas chromatography-mass spectrometry (GC-MS) technique, which accounted that β-caryophyllene contains the highest amount among the other 43 components present.

scholarly journals Pinus Species as Prospective Reserves of Bioactive Compounds with Potential Use in Functional Food—Current State of Knowledge

Plants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1306
Author(s):  
Marcin Dziedziński ◽  
Joanna Kobus-Cisowska ◽  
Barbara Stachowiak
Keyword(s):  
Human Health ◽  
Bioactive Compounds ◽  
Functional Food ◽  
Biological Activities ◽  
Food Ingredients ◽  
Beneficial Effects ◽  
Pine Tree ◽  
Pine Trees ◽  
Health Promoting ◽  
Few Data

The pine (Pinus L.) is the largest and most heteromorphic plant genus of the pine family (Pinaceae Lindl.), which grows almost exclusively in the northern hemisphere. The demand for plant-based remedies, supplements and functional food is growing worldwide. Although pine-based products are widely available in many parts of the world, they are almost absent as food ingredients. The literature shows the beneficial effects of pine preparations on human health. Despite the wide geographical distribution of pine trees in the natural environment, there are very few data in the literature on the widespread use of pine in food technology. This study aims to present, characterise and evaluate the content of phytochemicals in pine trees, including shoots, bark and conifer needles, as well as to summarise the available data on their health-promoting and functional properties, and the potential of their use in food and the pharmaceutical industry to support health. Various species of pine tree contain different compositions of bioactive compounds. Regardless of the solvent, method, pine species and plant part used, all pine extracts contain a high number of polyphenols. Pine tree extracts exhibit several described biological activities that may be beneficial to human health. The available examples of the application of pine elements in food are promising. The reuse of residual pine elements is still limited compared to its potential. In this case, it is necessary to conduct more research to find and develop new products and applications of pine residues and by-products.

scholarly journals Possibilities of the Development of Edible Insect-Based Foods in Europe

Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 766
Author(s):  
Magdalena Skotnicka ◽  
Kaja Karwowska ◽  
Filip Kłobukowski ◽  
Aleksandra Borkowska ◽  
Magdalena Pieszko
Keyword(s):  
Material Processing ◽  
Functional Food ◽  
The Other ◽  
Raw Material ◽  
Edible Insects ◽  
Mineral Salts ◽  
Edible Insect ◽  
Alternative Protein ◽  
The World ◽  
The One

All over the world, a large proportion of the population consume insects as part of their diet. In Western countries, however, the consumption of insects is perceived as a negative phenomenon. The consumption of insects worldwide can be considered in two ways: on the one hand, as a source of protein in countries affected by hunger, while, on the other, as an alternative protein in highly-developed regions, in response to the need for implementing policies of sustainable development. This review focused on both the regulations concerning the production and marketing of insects in Europe and the characteristics of edible insects that are most likely to establish a presence on the European market. The paper indicates numerous advantages of the consumption of insects, not only as a valuable source of protein but also as a raw material rich in valuable fatty acids, vitamins, and mineral salts. Attention was paid to the functional properties of proteins derived from insects, and to the possibility for using them in the production of functional food. The study also addresses the hazards which undoubtedly contribute to the mistrust and lowered acceptance of European consumers and points to the potential gaps in the knowledge concerning the breeding conditions, raw material processing and health safety. This set of analyzed data allows us to look optimistically at the possibilities for the development of edible insect-based foods, particularly in Europe.

scholarly journals Optimization of Microwave-Assisted Extraction of Phlorotannin From Sargassum swartzii (Turn.) C. Ag. With Ethanol/Water

2021 ◽  
Vol 16 (2) ◽  
pp. 1934578X2199618
Author(s):  
Tran Quoc Toan ◽  
Tran Duy Phong ◽  
Dam Duc Tien ◽  
Nguyen Manh Linh ◽  
Nguyen Thi Mai Anh ◽  
...  
Keyword(s):  
Output Power ◽  
Ethanol Concentration ◽  
Biological Activities ◽  
Solvent System ◽  
Extraction Process ◽  
Extraction Time ◽  
Brown Macroalgae ◽  
Experimental Conditions ◽  
Total Extract ◽  
Sargassum Swartzii

Sargassum is a genus of brown macroalgae in the class Phaeophyta, distributed widely in all oceans, including those of Vietnam. Species of this genus have been proven to possess diverse biological activities, such as antioxidant, anti-fungal, and anti-inflammatory, along with many benefits and applications for human health, including anti-diabetic, obesity, and thrombosis. These benefits arise from a diverse chemical composition, with compounds such as fucoidan, mannitol, and especially phlorotannin—a group of phenolic derivatives found predominantly in brown algae. In this study, we evaluated and optimized the factors that affected the extraction process of phlorotannins from Sargassum swartzii (Turn.) C. Ag., a common species of brown macroalgae in Vietnam. The process utilized ethanol and water as the solvent system, and the extraction process was assisted with the use of microwaves. To carry out optimization studies, Response Surface Methodology (RSM) was adopted according to a Central Composite Desisgn (CCD), taking four processing factors into consideration, ethanol concentration (%, v/v), extraction time (minutes), solvent/material ratio (v/w), and microwave output power (W) as independent variables. Phlorotannin concentration (mgPhE/g) and extract mass (mg) were regarded as optimization outcomes. Experimental conditions that produced the highest phlorotannin yield from 10 g of S. swartzii are as follows: Extraction time of 65 minutes, ethanol concentration of 52%, microwave output power of 613 W, and solvent/material ratio of 33/1 (v/w). These conditions corresponded to a phlorotannin concentration of 5.59 ± 0.11 mg PhE/g, and a total extract content of 27.88 ± 0.13 mg/g.

scholarly journals Optimization of Supercritical Extraction Conditions of Senna Alata and Evaluation of Biological Activity

2018 ◽  
Vol 7 (3.11) ◽  
pp. 94
Author(s):  
Istikamah Subuki ◽  
Aiman Nabilah Abdul Malek ◽  
Saidatul Husni Saidin ◽  
Mazura Md. Pisar
Keyword(s):  
Crude Extract ◽  
Extraction Process ◽  
Quadratic Model ◽  
Total Flavonoids ◽  
Inhibition Activity ◽  
Backward Elimination ◽  
Total Flavonoids Content ◽  
Senna Alata ◽  
Central Composite ◽  
Experimental Runs

Supercritical fluid extraction (SFE) offer faster extraction process, decreased solvent usage and more selectivity on desired compounds. In this present study, the influence of pressure (100, 200 and 300 bar) and temperature (40, 50 and 60˚C) on the Senna alata crude yield were investigated with fixed supercritical carbon dioxide (SC-CO2) at the flow rate of 35 g/min. The parameters were optimised and modelled using response surface methodology (RSM) and central composite design (CCD). The analysis of variance (ANOVA) experimental design consists of 13 experimental runs with 5 replicates at the central points. Well-fitting quadratic model were successfully established for crude extract through backward elimination. The optimum crude extract yield pointed out by RSM was at the pressure of 300 bar and temperature 40˚C respectively. Extraction yields based on SC-CO2 varied in the range of 0.28 to 3.62%. The highest hyaluronidase inhibition activity and total flavonoids content obtained by S.alata crude extracts were 41.19% and 52.53% w/w, respectively. SC-CO2 proves to have great potential for extraction of yield, hyaluronidase inhibition activity and total flavonoids content for S.alata.  

scholarly journals Synthesis, Characterization, and Agricultural Biological Activities of 5-Fluoro-2-hydroxy Butyrophenone

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Fengli Xin ◽  
Chunhua Du ◽  
Gongjia Lan ◽  
Zhuanping Wu
Keyword(s):  
Lactuca Sativa ◽  
Biological Activities ◽  
Raw Material ◽  
Synthetic Approach ◽  
Target Compound ◽  
Echinochloa Crusgalli ◽  
Agricultural Plant ◽  
H Nmr ◽  
Valsa Mali ◽  
C Nmr

A novel synthetic approach towards 5-fluoro-2-hydroxy butyrophenone is reported. Using 4-fluorophenol as a raw material, the processes of etherification protection, Friedel-Crafts acylation and demethylation provide the target compound under mild conditions. The structure was characterized by the melting point and IR, MS,1H-NMR, and13C-NMR spectroscopy. The bioassay results indicate that the target compound exhibits potent antifungal activities againstValsa mali,Coniella dipodiella, and other agricultural plant fungi. The target compound also shows potent herbicidal activities forLactuca sativa, a dicotyledon, andEchinochloa crus-galli, a monocotyledon. The toxicity regression C50values of the compound againstValsa mali,Coniothyrium diplodiella,Lactuca sativaseedling, andEchinochloa crusgalliseedling were calculated by SPSS. The Hormesis effect for roots ofEchinochloa crusgalliwas confirmed.

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