Potential Effects of a Modified Mediterranean Diet on Body Composition in Lipoedema

Lipoedema is a subcutaneous adipose tissue disease characterized by the increase in the amount and structure of fat mass (FM) in specific areas, causing pain and discomfort. 95% of patients fail to lose weight in the lipoedema areas. The study was conducted to evaluate body composition and general health status modification in a group of lipoedema patients (LIPPY) and a control group (CTRL) after four weeks of a modified Mediterranean diet therapy (mMeD). A total of 29 subjects were included in the data analysis, divided in two groups: 14 LIPPY and 15 CTRL. After the mMeD, both groups significantly decreased their weight and body mass index; the CTRL also showed a reduction of all the circumferences and all FM’s compartments. LIPPY showed a decrease of FM in upper and lower limbs. No significant differences in Δ% between the groups were observed for the lean mass (LM). In LIPPY, an increase in the patients’ ability to perform various daily physical activities related to the loss of arms’ and legs’ fat was observed. According to the European Quality of Life scale, the possibility for LIPPY subjects to perform simple daily activities with less fatigue, pain and anxiety is highlighted. Further long-term studies are recommended to confirm the mMeD as a good strategy for Lipoedema treatment.

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Phase angle and Mediterranean diet in patients with acne: Two easy tools for assessing the clinical severity of disease

Journal of Translational Medicine ◽

10.1186/s12967-021-02826-1 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Luigi Barrea ◽

Marianna Donnarumma ◽

Sara Cacciapuoti ◽

Giovanna Muscogiuri ◽

Ludovica De Gregorio ◽

...

Keyword(s):

Body Composition ◽

Mediterranean Diet ◽

Phase Angle ◽

Inflammatory Diseases ◽

Bioelectrical Impedance ◽

Dietary Factors ◽

Clinical Severity ◽

Control Group ◽

Cross Sectional ◽

Severe Acne

Abstract Background Acne is a chronic, inflammatory and debilitating skin disorder. Dietary factors and nutritional status are among the exacerbating factors of acne. Phase angle (PhA), a direct measure of Bioelectrical Impedance Analysis (BIA), represents an indicator of the chronic inflammatory state. The Mediterranean diet (MD) is a healthy dietary pattern that can exert anti-inflammatory effects in several inflammatory diseases. We aimed to investigate the difference in PhA and adherence to the MD and their associations with the severity of acne in a sample of naïve treatment patients with acne compared to control group. Materials In this cross-sectional, case–control, observational study, we enrolled 51 patients with acne and 51 control individuals. Body composition was evaluated by a BIA phase-sensitive system (50 kHz BIA 101 RJL, Akern Bioresearch, Florence, Italy, Akern). For adherence to the MD, we have used the PREvención con DIeta MEDiterránea (PREDIMED) questionnaire. The clinical severity of acne was assessed by using the global acne grading system (GAGS), a quantitative scoring system to assess acne severity. Results Patients with acne had a worse body composition, in particular smaller PhA (p = 0.003), and a lower adherence to the MD (p < 0.001) than the control group, in spite of no differences in gender, age and BMI between the two groups. Stratifying patients with acne according to GAGS categories, both PhA (p = 0.006) and PREDIMED score (p = 0.007) decreased significantly in severe acne than mild/moderate acne. The GAGS score was negative correlations with PhA (r = − 0.478, p < 0.001) and PREDIMED score (r = − 0.504, p < 0.001). The results of the multivariate analysis showed PhA and PREDIMED score were the major determinants of GAGS score (p < 0.001). The receiver operator characteristic (ROC) analysis reporting a value of PhA of ≤ 6.1° and a PREDIMED score of ≤ 9 identified patients with acne with the highest clinical severity of the disease. Conclusions Novel correlations were reported between PhA and the degree of adherence to the MD with acne severity. Of interest, PhA and PREDIMED scores might represent possible markers of the severity of acne in a clinical setting. This study highlights how a cooperation between dermatologist and nutritionists might provide a combination key in the complex management of acne patients.

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Body composition, lipid profile and mediterranean diet adherence in cardiovascular disease patients attending a long-term exercise-based cardiac rehabilitation program during COVID-19 pandemic

European Journal of Preventive Cardiology ◽

10.1093/eurjpc/zwab061.187 ◽

2021 ◽

Vol 28 (Supplement_1) ◽

Author(s):

M Linan Pinto ◽

R Pinto ◽

S Charneca ◽

J Vasques ◽

M Lemos Pires ◽

...

Keyword(s):

Cardiovascular Disease ◽

Body Composition ◽

Lipid Profile ◽

Mediterranean Diet ◽

Dietary Patterns ◽

Nutritional Intervention ◽

Phase Iii ◽

Body Composition Assessment ◽

Metabolic Complications

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Cardiovascular disease (CVD) is recognized as a major public health issue and remains the leading cause of mortality worldwide. There is a clear association between adiposity, blood lipid profile, and adherence to the Mediterranean diet (MD) with the risk of CVD. However, the assessment of body composition parameters, dietary patterns and nutritional intervention in CVD patients undergoing a cardiovascular rehabilitation (CR) program remains insufficient. Purpose to characterize body composition, lipid profile and MD adherence in patients with CVD who were attending an exercise-based CR program during COVID-19 era. Methods The study was developed between October 2020 and January 2021 in a phase III centre-based CR program. Body composition was assessed by dual energy x-ray absorptiometry Hologic Explorer-W. Adherence to the MD was assessed by the 14-item MD questionnaire. Fasting blood sample was taken for measurement of lipid profile. Results A sample of 41 patients (mean age 64.4 ± 7.9 years, 87.8% male) was evaluated. The most prevalent CVD were coronary artery disease (89.5%) and heart failure (21.1%). The main CVD risk factors at admission in the CR program were dyslipidaemia (71.1%), hypertension (68.4%), physical inactivity (26.3%) and diabetes mellitus (21.0%). In our sample the mean body mass index was 28 ± 3.8 kg/m2, being most patients overweight (75.6%), and having a substantially increased risk of metabolic complications (85.3%) accordingly to waist-hip ratio. Body composition assessment showed that 14.6% of the patients had a body fat mass index above 90th percentile. Although only 9.8% of the patients had reduced fat free mass, 17.1% showed appendicular lean mass below the reference value. In addition, less than one third of the patients (31.7%) revealed a high adherence to the MD pattern. A sub-analysis on blood lipids (n = 26) showed that most patients had levels of LDL cholesterol (76.9%) and non-HDL cholesterol (65.4%) above the therapeutic target and 15.4% had triglycerides higher than 150 mg/dl. Conclusion Body composition, lipid profile and dietary patterns, play a major role in CVD secondary prevention. Our findings showed that a substantial number of CVD patients, in COVID-19 era, did not have optimal body composition, were above lipid profile targets, and had a low/medium adherence to the MD. Thus, this study highlights the relevance of nutrition on cardiometabolic status and demonstrates the crucial role of nutritional intervention as an integrated part of a long-term phase III CR program. Moreover, further research about nutritional intervention in patients undergoing CR is warranted.

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An Adjustable Implant for the Nasal Valve: 3-Year Experience

Otolaryngology ◽

10.1016/j.otohns.2008.05.233 ◽

2008 ◽

Vol 139 (2_suppl) ◽

pp. P72-P72

Author(s):

Charles G Hurbis

Keyword(s):

Nasal Valve ◽

Valve Dysfunction ◽

Nasal Airways ◽

Quality Of Life Scale ◽

Life Scale ◽

Nasal Implant ◽

Scale Data ◽

Implantation Success

Objective 1) Measure the effectiveness of the Monarch implant in correcting nasal valve dysfunction. 2) Determine the longevity of effectiveness. Methods This study consists of a prospective, cumulative, three-year experience with the Monarch adjustable nasal implant for correcting nasal valve dysfunction in a total of 46 patients. Implantation success was determined by the use of acoustic rhinomanometry and a subjective NOSE-type quality of life scale. Data was subjected to the student-t test. Results In the series of 46 patients spanning 36 months there is a mean 150% improvement in the internal nasal valve areas at 3 years as measured by acoustic rhinomanometry (p<.0001). Using a NOSE-type questionnaire, patients also noted significant improvements in daytime (p<.0004) and nighttime (p<.0002) nasal airways, a decrease in apnea (p<.01) and snoring (p<.05), and a decrease in the propensity for daytime oral breathing (p<.0002). Conclusions The Monarch Implant provides a simple, consistent, adjustable and apparently long-term correction of the nasal airway in patients suffering from nasal valvular dysfunction.

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Evaluation of a Novel Quality of Life Scale for Schoolchildren with Nonstrabismic Binocular Vision Anomalies

BioMed Research International ◽

10.1155/2020/4723402 ◽

2020 ◽

Vol 2020 ◽

pp. 1-7

Author(s):

Jiali Hu ◽

Guokun Wang ◽

Zhe Zhou ◽

Yan Sun ◽

Qingling Zhang ◽

...

Keyword(s):

Quality Of Life ◽

Binocular Vision ◽

Discriminant Validity ◽

Life Quality ◽

Life Assessment ◽

Average Score ◽

Control Group ◽

Quality Of Life Scale ◽

Life Scale

Background. The professional Quality of Life Scale (QLS) can provide a valuable reference for the diagnosis of visual function anomalies. In the present study, we aimed to design a novel QLS to specially quantify the life quality of schoolchildren with nonstrabismic binocular vision anomalies (NSBVAs) in China. Methods. The novel QLS, named QOL-CVF20, was established based on classical vision-related scales and the administration of the questionnaire to 116 schoolchildren with NSBVAs and 100 healthy schoolchildren in China. The diagnostic reference value between QOL-CVF20 and VF-14 was evaluated on the questionnaires to 240 schoolchildren with NSBVAs and 238 healthy schoolchildren. Results. All the subjects could complete the QOL-CVF20 questionnaires independently. QOL-CVF20 had good structural validity, content validity, and discriminant validity, when it was applied in Chinese schoolchildren. The average score of the NSBVA group was significantly lower than that of the control group (49.0±6.9 vs. 69.7±6.7, respectively; P<0.01). Moreover, the average score of cured NSBVA schoolchildren after treatment (61.8±22.6) was significantly improved (P<0.01). Receiver operating characteristic curve analysis showed that QOL-CVF20 reflected strong separation between the NSBVA and healthy groups (AUC=0.901). Meanwhile, QOL-CVF20 could detect individuals with NSBVAs with specificity of 0.847 and sensitivity of 0.846. The critical value of 58.50 in QOL-CVF20 could be effectively applied for quality of life assessment in schoolchildren with NSBVAs. Conclusions. QOL-CVF20 could quantify the life quality of schoolchildren with NSBVAs and might be served as a valuable reference for early diagnosis and clinical evaluation of NSBVAs.

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Welfare of cats 5–29 months after perineal urethrostomy: 74 cases (2015–2017)

Journal of Feline Medicine and Surgery ◽

10.1177/1098612x19867777 ◽

2019 ◽

Vol 22 (6) ◽

pp. 582-588 ◽

Cited By ~ 1

Author(s):

Margaret R Slater ◽

Sharon Pailler ◽

J’mai M Gayle ◽

Illoneete Cohen ◽

Erin L Galloway ◽

...

Keyword(s):

Quality Of Life ◽

Case Series ◽

Life Outcomes ◽

Retrospective Case ◽

Quality Of Life Scale ◽

Life Scale ◽

Potential Factors ◽

American Society

Objectives The objective of this study was to evaluate the long-term quality of life in cats following perineal urethrostomy. Methods This study comprised a retrospective case series of 74 cats with urinary obstructions that received perineal urethrostomies at the American Society for the Prevention of Cruelty to Animals (ASPCA) Animal Hospital between September 2015 and July 2017. Medical records were reviewed for information on the number of obstructions prior to surgery, urinary tract problems at the time of surgery and other potential factors influencing long-term welfare. Owners were surveyed by telephone and text 5–29 months after their cat’s surgery. Responses were compiled and analyzed to determine owner perception of welfare postsurgery, and to identify patterns in medical history and welfare outcomes. Results In total, 105 cat owners were eligible for the survey; 74 responded. Altogether, 100% of responding individuals reported at least the same quality of life postsurgery compared with the cat’s quality of life before demonstrating urinary problems (48% reported better). On a quality-of-life scale of 1–10 (10 = excellent), 100% of responding cat owners reported at least 7; 75% reported 10. Conclusions and relevance Quality-of-life outcomes for cats 5–29 months after receiving perineal urethrostomy surgery were reported to be very good. Given this finding, and that perineal urethrostomy surgery should mitigate future blockages, we suggest considering perineal urethrostomy surgery as a standard tool to manage urinary obstructions in cats. The needs of the specific client and patient, including risks, costs and welfare of the cats, should drive the options for management of urinary obstructions in male cats.

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Analisis of quality of life long-term hospitalized schizophrenic patients

European Psychiatry ◽

10.1016/s0924-9338(11)73217-5 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 1513-1513 ◽

Cited By ~ 1

Author(s):

G. Tasic ◽

S. Anakiev ◽

D. Milosevic ◽

M. Cvetanovic

Keyword(s):

Quality Of Life ◽

Rating Scale ◽

Length Of Hospital Stay ◽

Hospital Treatment ◽

Quality Of Life Scale ◽

Life Scale ◽

Icd 10 ◽

Schizophrenic Patients

IntroductionLong term hospitalization are often caused by social reasons wich significantly affects the quality of the patients.AimComparing the quality of long-term hospitalized schizophrenic patients in relation to sex.MethodWe have used following rating scale: a brief psychiatric assessment scale BPRS, QLS Quality of life scale, “Lancashir” profile quality of life scale LQOLP, a short questionnaire for the “needs assessment Cambersels” scale CANSAS. Analysis included 80 inpatients, 40 male and 40 female, with Schizophrenia according to ICD 10 criteria. All patients were hospitalized according to ICD 10 criteria. All patients were hospitalized in a Special Hospital For Psychiatric Illness G. Toponica more than two years.ResultsSignificant differences in quality of life between male and female patients about what is discussed in further study.ConclusionsResearch has shown that long-term hospitalizing has adverse effects on quality of life of schizophrenic patients of both sexes. His essential that the length of hospital stay should be reduced to the period reduced to the period for reduction of symptoms and provide the patient a stable life in the community after hospital treatment.

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Burnout and distress in Australian physician trainees: Evaluation of a wellbeing workshop

Australasian Psychiatry ◽

10.1177/1039856219833793 ◽

2019 ◽

Vol 27 (3) ◽

pp. 255-261 ◽

Cited By ~ 2

Author(s):

Carmen Axisa ◽

Louise Nash ◽

Patrick Kelly ◽

Simon Willcock

Keyword(s):

Alcohol Use ◽

Statistical Significance ◽

Intervention Group ◽

Control Group ◽

Depression Anxiety Stress Scale ◽

Screening Criteria ◽

Quality Of Life Scale ◽

Life Scale ◽

Workshop Intervention ◽

And Control

Objective: To evaluate the effectiveness of a workshop intervention to promote wellbeing for Australian physician trainees using a randomized-controlled design. Methods: Participants were randomly assigned into intervention and control groups. The intervention group attended a half-day workshop. Outcome measures included depression anxiety stress scale, professional quality of life scale and alcohol use disorders identification test. Demographic and work/life factors were measured. Measurements were recorded at baseline, 3 and 6 months, and the workshop was evaluated by participants. Results: High rates of burnout (76%) and secondary traumatic stress (91%) were detected among study participants and around half met screening criteria for depression (52%), anxiety (46%) and stress (50%) at baseline. Workshop evaluations showed that participants agreed that the training was relevant to their needs (96%) and met their expectations (92%). There was a small reduction in alcohol use, depression and burnout in the intervention group compared with the control group at 6 months, but these changes did not reach statistical significance. Conclusion: High rates of psychological morbidity detected in the study suggest that physician trainees are a vulnerable group who may benefit from initiatives that promote wellbeing and changes in the workplace to reduce distress.

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Influence of COPD Assessment Text (CAT) evaluation and rehabilitation education guidance on the respiratory and motor functions of COPD patients

Open Medicine ◽

10.1515/med-2015-0062 ◽

2015 ◽

Vol 10 (1) ◽

Cited By ~ 2

Author(s):

Jing Liu ◽

Guangju Meng ◽

Yi Ma ◽

Xia Zhang ◽

Dongmei Chen ◽

...

Keyword(s):

Inhaled Corticosteroids ◽

Life Quality ◽

Control Group ◽

Chronic Obstructive ◽

Study Group ◽

Motor Functions ◽

Obstructive Pulmonary Disease ◽

Copd Patients ◽

Quality Of Life Scale ◽

Life Scale

Abstract The study aimed to evaluate the influence of the COPD Assessment Test (CAT) evaluation and rehabilitation education guidance on the respiratory and motor functions of patients with chronic obstructive pulmonary disease (COPD). Forty-five patients with COPD admitted from Nov. 2012 to Nov. 2013 were treated with combined bronchodilators and inhaled corticosteroids. Thirty-five patients admitted from Nov. 2012 to Nov. 2013 and classified as a study group received rehabilitation education guidance on the basis of the treatment of the control group to compare the quality-of-life-scale score, dyspnea index score, and motor function of the two groups of patients after 48 weeks of treatment. After treatment, the CAT score of both groups of patients was significantly lowered. After 48 weeks of treatment, the respiratory function of both groups was significantly improved, but the Medical Research Council (MRC) scale for the study group after treatment was significantly lower than that for the control group. After 48 weeks of rehabilitation exercises, the 6-minute walk test (6MWT) for patients with COPD was significantly prolonged, but the test results were significantly higher for the study group after treatment than for the control group. After receiving CAT rehabilitation education, COPD patients had significantly improved life quality and significantly enhanced exercise tolerance. The treatment mode may be gradually introduced in future clinic and nursing work.

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A Multicentre Randomized Clinical Trial on Efficacy and Safety of Huxin Formula in Patients Undergoing Percutaneous Coronary Intervention

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2014/143064 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Huan-Lin Wu ◽

Yun-Fei Wang ◽

Jun-Zhe Li ◽

Min-Zhou Zhang ◽

Xiao-Gang Sheng ◽

...

Keyword(s):

Quality Of Life ◽

Clinical Trial ◽

Percutaneous Coronary Intervention ◽

Treatment Group ◽

Coronary Intervention ◽

Control Group ◽

Percutaneous Coronary ◽

Quality Of Life Scale ◽

Life Scale

Percutaneous coronary intervention (PCI) is widely used in clinical treatment of coronary artery disease. However, the effects of PCI on preventing restenosis after revascularization and improving the quality of life were not satisfying. Huxin Formula is formulated by modifying an experienced Chinese medicine formula and has been widely used in clinical practice due to its marked effects on coronary heart disease. A multicentre double-blind randomized controlled clinical trial was designed to evaluate the effects and safety of Huxin Formula in patients undergoing PCI. Our results showed that there was no significant difference between the two groups in main outcomes. For patients with ejection fraction (EF)>50%, score of the quality of life scale was higher in treatment group compared with control group. For patients with unstable angina, score of the quality of life scale in 360 days was significantly higher in treatment group compared with control group (P<0.05). No obvious adverse reaction was found in the use of Huxin Formula. In conclusion, Huxin Formula, believed to be a safe treatment for patients after PCI, has benefits in improving the quality of life in patients with unstable angina though it failed to show superiority in primary and secondary outcomes.

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Effect of Training and Detraining in the Components of Physical Fitness in People Living With HIV/AIDS

Frontiers in Physiology ◽

10.3389/fphys.2021.586753 ◽

2021 ◽

Vol 12 ◽

Author(s):

Juliany de Souza Araujo ◽

Rafaela Catherine da Silva Cunha de Medeiros ◽

Tatiane Andreza Lima da Silva ◽

Danielle Coutinho de Medeiros ◽

Jason Azevedo de Medeiros ◽

...

Keyword(s):

Body Composition ◽

Cardiorespiratory Fitness ◽

Ventilatory Threshold ◽

Lower Limbs ◽

Control Group ◽

People Living With Hiv ◽

Combined Training ◽

Living With Hiv ◽

Training And Detraining ◽

Hiv Aids

The aim of the study was to evaluate the effect of training and detraining on the physical fitness components of people living with HIV/AIDS (PLHA). The study was characterized as experimental with a sample composed of 21 people divided into two groups: 11 volunteers (PLHA, 46.9 ± 8.0 years, 63.8 ± 12.7 kg, 161.7 ± 8.7 cm, 7 men, and 4 women), using antiretroviral therapy (ART) and 10 people without HIV/AIDS in the control group (CG, 43.8 ± 13.8 years, 75.2 ± 11.2 kg, 163.3 ± 7.8 cm, 3 men, and 7 women), with the same average age and level of physical activity. The intervention, applied to both groups, consisted of combined training for 15 weeks, followed by detraining for 5 weeks. Before and after the training and detraining period the following parameters were evaluated: body composition by dual energy radiological absorptiometry (DXA), cardiorespiratory fitness by ergospirometer, and strength of upper and lower limbs by isometric dynamometer. The results show the effect of the intervention moments on the strength and oxygen consumption variables (time factor), considering the two study groups. Regarding the analysis of the interaction (group vs. time), there was a significant effect on the isometric extension strength of the left (p = 0.019) and right (p = 0.030) knees, with training (left: 10.4%; right: 12.4%) and detraining (left: −10.8%; right: −12.1%) effect in PLHA, when compared with the control group (left: 8.1 and 3.9%, respectively; right: 11.5 and −0.2%, respectively). In addition, there was a significant interaction on ventilatory threshold 1 (p = 0.002), indicating a significantly greater increase with training (27.3%) and decrease with detraining (−22.7%) in the PLHA group compared with the Control group (19.9 and −6.7%, respectively). In conclusion, combined training and the subsequent period of detraining caused similar responses in body composition, isometric strength, and cardiorespiratory fitness of PLHA and CG, except for the extensor strength of the lower limbs and ventilatory threshold 1, which presented positive effects on training and negative effects on detraining for PLHA.Clinical Trial Registration:www.ClinicalTrials.gov, identifier NCT03075332.

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