scholarly journals Vitamins in Human and Donkey Milk: Functional and Nutritional Role

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1509
Author(s):  
Silvia Vincenzetti ◽  
Giuseppe Santini ◽  
Valeria Polzonetti ◽  
Stefania Pucciarelli ◽  
Yulia Klimanova ◽  
...  
Keyword(s):  
Human Milk ◽  
Dairy Cows ◽  
Mammalian Species ◽  
The Elderly ◽  
Health Impact ◽  
Cow Milk ◽  
Donkey Milk ◽  
Positive Health ◽  
Vitamin Status ◽  
Fat Soluble Vitamins

Background: Whole milk is a good source of all the nutrients, and it also contains a sufficient number of vitamins to permit regular the growth of the neonate. Dairy cow milk can create allergy in infants less than 12 months old because of the high caseins and β-lactoglobulin content. In these circumstances, donkey milk can represent a good replacement for dairy cows’ milk in children affected by Cow Milk Protein Allergy (CMPA) because of its close chemical composition with human milk, mainly due to its low protein and low mineral content. Milk vitamin content is highly variable among mammalian species and it is strictly correlated with the vitamin status and the diet administered to the mother. Fat-soluble vitamins content in donkey milk is, on average, lower compared to ruminants’ milk, while vitamin C content determined in donkey milk is higher compared to dairy cows’ milk, showing a great similarity with human milk. In donkey milk, the content of vitamins of the B-complex such as thiamine, riboflavin, niacin, pyridoxine, and folic acid is higher compared to human milk. The use of donkey milk as a new functional food must be further evaluated in interdisciplinary clinical trials in which pediatricians, dietitians, and food scientists must be involved to deepen the knowledge about the positive health impact of donkey milk in different sensitive people, especially children and the elderly.

Towards an Affordable Human Waste Management Programme for the Poor – A Report on Bangladesh

1986 ◽  
Vol 18 (7-8) ◽  
pp. 33-40
Author(s):  
K. M. Minnatullah
Keyword(s):  
Waste Management ◽  
Disease Transmission ◽  
Limited Resource ◽  
Health Impact ◽  
Management Programme ◽  
Oral Disease ◽  
Personal Hygiene ◽  
Positive Health ◽  
Water And Sanitation ◽  
Human Waste

Nearly 80% of all illness in Bangladesh is related to water and sanitation. The combined rate of enteric diseases in Bangladesh is the highest in the world. 30% of all the deaths of children under 5 are due to diarrhoea, claiming more than 200,000 lives annually. Environmentally sound human waste management, along with personal hygiene awareness, are of critical importance to the prevention of faecal-oral disease transmission. present rural sanitation coverage is about 3%. A national target has been set to ensure that 13% of the rural poor will be covered under the human waste management programme by 1990, the end of the U.N. Water Decade. This however, contrasts with the similar target of 77% for the rural water supply programme, which received higher resource allocation and priority for a much longer period. This lack of correlation between water and sanitation has highly reduced the positive health impact of these developments. An affordable human waste management programme for the rural people, where 87% of the total population lives under conditions of the greatest poverty and underdevelopment, urgently needs serious and realistic consideration in the context of the limited resource prospects for future years. This report addresses the above issues and describes the commendable momentum that has been gained through the continuous efforts of national planners and policy makers. It is hoped that this might in the near future, through the rural human waste management programme, produce the long desired continual reduction of faecal-oral disease transmission.

scholarly journals Flavonoid-Modifying Capabilities of the Human Gut Microbiome—An In Silico Study

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2688
Author(s):  
Tobias Goris ◽  
Rafael R. C. Cuadrat ◽  
Annett Braune
Keyword(s):  
Gut Microbiome ◽  
Large Scale ◽  
Health Impact ◽  
Gut Bacteria ◽  
Human Gut ◽  
Positive Health ◽  
Human Gut Microbiome ◽  
Nutritional Recommendations ◽  
Genes Encoding ◽  
A Minor

Flavonoids are a major group of dietary plant polyphenols and have a positive health impact, but their modification and degradation in the human gut is still widely unknown. Due to the rise of metagenome data of the human gut microbiome and the assembly of hundreds of thousands of bacterial metagenome-assembled genomes (MAGs), large-scale screening for potential flavonoid-modifying enzymes of human gut bacteria is now feasible. With sequences of characterized flavonoid-transforming enzymes as queries, the Unified Human Gastrointestinal Protein catalog was analyzed and genes encoding putative flavonoid-modifying enzymes were quantified. The results revealed that flavonoid-modifying enzymes are often encoded in gut bacteria hitherto not considered to modify flavonoids. The enzymes for the physiologically important daidzein-to-equol conversion, well studied in Slackiaisoflavoniconvertens, were encoded only to a minor extent in Slackia MAGs, but were more abundant in Adlercreutzia equolifaciens and an uncharacterized Eggerthellaceae species. In addition, enzymes with a sequence identity of about 35% were encoded in highly abundant MAGs of uncultivated Collinsella species, which suggests a hitherto uncharacterized daidzein-to-equol potential in these bacteria. Of all potential flavonoid modification steps, O-deglycosylation (including derhamnosylation) was by far the most abundant in this analysis. In contrast, enzymes putatively involved in C-deglycosylation were detected less often in human gut bacteria and mainly found in Agathobacter faecis (formerly Roseburia faecis). Homologs to phloretin hydrolase, flavanonol/flavanone-cleaving reductase and flavone reductase were of intermediate abundance (several hundred MAGs) and mainly prevalent in Flavonifractor plautii. This first comprehensive insight into the black box of flavonoid modification in the human gut highlights many hitherto overlooked and uncultured bacterial genera and species as potential key organisms in flavonoid modification. This could lead to a significant contribution to future biochemical-microbiological investigations on gut bacterial flavonoid transformation. In addition, our results are important for individual nutritional recommendations and for biotechnological applications that rely on novel enzymes catalyzing potentially useful flavonoid modification reactions.

scholarly journals Current Knowledge on Functionality and Potential Therapeutic Uses of Donkey Milk

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1382
Author(s):  
Mina Martini ◽  
Iolanda Altomonte ◽  
Domenico Tricò ◽  
Riccardo Lapenta ◽  
Federica Salari
Keyword(s):  
Animal Models ◽  
Randomized Clinical Trials ◽  
Current Knowledge ◽  
Saturated Fatty Acids ◽  
Cow Milk ◽  
Donkey Milk ◽  
Alpha Linolenic Acid ◽  
High Concentration

The increase of knowledge on the composition of donkey milk has revealed marked similarities to human milk, which led to a growing number of investigations focused on testing the potential effects of donkey milk in vitro and in vivo. This paper examines the scientific evidence regarding the beneficial effects of donkey milk on human health. Most clinical studies report a tolerability of donkey milk in 82.6–98.5% of infants with cow milk protein allergies. The average protein content of donkey milk is about 18 g/L. Caseins, which are main allergenic components of milk, are less represented compared to cow milk (56% of the total protein in donkey vs. 80% in cow milk). Donkey milk is well accepted by children due to its high concentration of lactose (about 60 g/L). Immunomodulatory properties have been reported in one study in humans and in several animal models. Donkey milk also seems to modulate the intestinal microbiota, enhance antioxidant defense mechanisms and detoxifying enzymes activities, reduce hyperglycemia and normalize dyslipidemia. Donkey milk has lower calorie and fat content compared with other milks used in human nutrition (fat ranges from 0.20% to 1.7%) and a more favourable fatty acid profile, being low in saturated fatty acids (3.02 g/L) and high in alpha-linolenic acid (about 7.25 g/100 g of fat). Until now, the beneficial properties of donkey milk have been mostly related to whey proteins, among which β-lactoglobulin is the most represented (6.06 g/L), followed by α-lactalbumin (about 2 g/L) and lysozyme (1.07 g/L). So far, the health functionality of donkey milk has been tested almost exclusively on animal models. Furthermore, in vitro studies have described inhibitory action against bacteria, viruses, and fungi. From the literature review emerges the need for new randomized clinical trials on humans to provide stronger evidence of the potential beneficial health effects of donkey milk, which could lead to new applications as an adjuvant in the treatment of cardiometabolic diseases, malnutrition, and aging.

scholarly journals Vacuum Dynamics as an Alternative Method for Detection of Bimodal Milk Ejection in Dairy Cows

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1860
Author(s):  
Matthias Wieland ◽  
Christina Marie Geary ◽  
Gloria Gioia ◽  
Kerry Lynn Case ◽  
Paolo Moroni ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Predictive Value ◽  
Primary Objective ◽  
Cow Milk ◽  
Kappa Statistics ◽  
Flow Meter ◽  
Flow Curves ◽  
Cross Sectional ◽  
Gold Standard Method ◽  
Milk Flow

The primary objective of our study was to assess the ability of a vacuum recorder to detect the presence of bimodal milk flow curves in dairy cows compared with a portable milk flow meter. In a cross-sectional study, 241 individual cow milking observations were analyzed. We simultaneously collected (1) individual cow vacuum events during milking using portable vacuum recorders, and (2) individual cow milk flow curves by attaching a portable milk flow meter to the same milking unit. Presence of bimodality was assessed with the vacuum recorder visually (BIMVA) and with the gold standard method of a milk flow meter through automatic detection (BIMLA). Kappa statistics revealed moderate agreement between BIMVA and BIMLA [κ, 95% confidence intervals (95% CI) = 0.59 (0.46–0.71)]. Diagnostic test statistics for BIMVA for detection of bimodality indicated moderate performance for sensitivity [0.65 (0.52–0.76)] and positive predictive value [0.71 (0.58–0.82)] and high values for specificity [0.92 (0.87–0.95)] and negative predictive value [0.93 (0.84–0.93)]. We conclude that milking vacuum dynamics are a suitable measure to assess bimodal milk flow curves in dairy cows.

A new conjugated linoleic acid isomer, 7 trans, 9 cis-octadecadienoic acid, in cow milk, cheese, beef and human milk and adipose tissue

Lipids ◽  
1998 ◽  
Vol 33 (8) ◽  
pp. 803-809 ◽  
Author(s):  
Martin P. Yurawecz ◽  
John A. G. Roach ◽  
Najibullah Sehat ◽  
Magdi M. Mossoba ◽  
John K. G. Kramer ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Linoleic Acid ◽  
Human Milk ◽  
Conjugated Linoleic Acid ◽  
Octadecadienoic Acid ◽  
Cow Milk ◽  
Conjugated Linoleic Acid Isomer ◽  
Linoleic Acid Isomer

scholarly journals Effect of Fat on Protein Estimation in Milk and Its Correlation with Lactose in Different Milk Types: A Small-Scale Study

2020 ◽  
Author(s):  
Sweekruthi A. Shetty ◽  
Melissa F. Young ◽  
Sunita Taneja ◽  
Kannan Rangiah
Keyword(s):  
Sample Preparation ◽  
Human Milk ◽  
Internal Standard ◽  
Cow Milk ◽  
Selected Reaction Monitoring ◽  
Small Scale ◽  
Milk Samples ◽  
Protein Estimation ◽  
Animal Milk ◽  
Fat Removal

Background: Estimation of macronutrients like protein and lactose is important to assess the quality of milk. To estimate these two macronutrients, ten raw milk samples obtained from each group of different animals (cow, goat, buffalo), ten pasteurized cow milk and ten human milk samples were analysed. Methods: Bicinchoninic acid (BCA) method was used to estimate protein from different milk samples. Four different sample preparation protocols were compared to check the effect of fat on BCA based protein estimation: dilution (D), fat removal-protein precipitation (FR and PP), fat removal-dilution (FR and D) and dilution-fat removal (D and FR). For lactose quantification, ultrahigh-performance liquid chromatography-mass spectrometry-selected reaction monitoring (UHPLC-MS/SRM) method was developed and validated using 13C6 lactose as internal standard (ISTD).Result: Among these four different protocols, D and FR method showed consistent data for total protein content in animal milk (cow-3.16%, goat-3.21%, buffalo-3.81%, pasteurized-2.98%) and FR and PP showed consistent data in human milk samples (1.2%). Though BCA method is simple to use, proper sample preparation protocol has to be applied prior to protein estimation to avoid the interference due to fat or lactose. In case of lactose, inter-day validation showed the accuracy ranging from 97.13 to 100.54%, coefficient of variation varying between 0.1 to 1.53%, correlation R2=0.999. Lactose is in the range of 4.1 to 4.8% in animal milk and 6.6% in human milk samples. The internal ratio of lactose/protein (1.28 to 1.55 in animal milk and 5.33 in human milk) will be useful to differentiate human milk from animal milk type and to assess the milk quality.

scholarly journals INVESTIGATION AMINO ACID COMPOSITION OF DONKEY’S MILK OF THE KEGETY GORGE

InterConf ◽  
2021 ◽  
pp. 363-369
Author(s):  
Nadira Turganbaeva ◽  
Dinara Isakova
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Human Milk ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Sugar Content ◽  
Essential Amino Acids ◽  
Cow’S Milk ◽  
Donkey Milk ◽  
Cow's Milk

The objective of this paper was to study the amino acid composition of donkey milk inhabiting the Kegety gorge of the Chui region. As well as human milk, donkey and mare’s milk is albumin; the amount of casein is 35-45%, while cow’s milk is casein milk with casein content over 75%. The peculiarity of albumin milk is a higher biological and nutritional value, due to better amino acid balance, high sugar content and the ability to form small, delicate flakes when souring. In terms of its properties, albumin milk is closest to human milk and is the best substitute for it. The obtained results showed that the quantitative content of 7 essential amino acids out of 8, such as lysine, phenylalanine, leucine, isoleucine, methionine, valine, threonine is relatively high compared to other amino acids. Despite the absence of tryptophan in donkey milk, the percentage of 8 essential amino acids in donkey milk protein exceeds that in mare and cow’s milk.

scholarly journals Elder Health Literacy

2004 ◽  
Vol 2 (3) ◽  
pp. 1-4 ◽  
Author(s):  
Lorraine Wallace
Keyword(s):  
Health Literacy ◽  
Health Education ◽  
Formal Education ◽  
Elderly Care ◽  
The Elderly ◽  
Health Impact ◽  
The Public ◽  
Low Health Literacy ◽  
Populations At Risk ◽  
Health Education Materials

The public health impact of limited literacy has begun to be explored. The elderly and those with limited formal education are often the most vulnerable populations at risk of having low health literacy. Health promotion specialists must be cognizant of the literacy demands of health education materials (e.g., pamphlets, questionnaires) distributed to the elderly. Care must be taken to ensure that health education materials are both linguistically and culturally appropriate for whom they are intended.

Intake of Medication and Vitamin Status in the Elderly

2011 ◽  
Vol 58 (2) ◽  
pp. 118-125 ◽  
Author(s):  
Elisabeth Fabian ◽  
Michaela Bogner ◽  
Andrea Kickinger ◽  
Karl-Heinz Wagner ◽  
Ibrahim Elmadfa
Keyword(s):  
The Elderly ◽  
Vitamin Status
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