scholarly journals Microfluidic Synthesis and Analysis of Bioinspired Structures Based on CaCO3 for Potential Applications as Drug Delivery Carriers

Pharmaceutics ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 139
Author(s):  
Ekaterina V. Lengert ◽  
Daria B. Trushina ◽  
Mikhail Soldatov ◽  
Alexey V. Ermakov

Naturally inspired biomaterials such as calcium carbonate, produced in biological systems under specific conditions, exhibit superior properties that are difficult to reproduce in a laboratory. The emergence of microfluidic technologies provides an effective approach for the synthesis of such materials, which increases the interest of researchers in the creation and investigation of crystallization processes. Besides accurate tuning of the synthesis parameters, microfluidic technologies also enable an analysis of the process in situ with a range of methods. Understanding the mechanisms behind the microfluidic biomineralization processes could open a venue for new strategies in the development of advanced materials. In this review, we summarize recent advances in microfluidic synthesis and analysis of CaCO3-based bioinspired nano- and microparticles as well as core-shell structures on its basis. Particular attention is given to the application of calcium carbonate particles for drug delivery.

2007 ◽  
Vol 52 (5) ◽  
pp. 1865-1870 ◽  
Author(s):  
Xiliang Luo ◽  
Anthony J. Killard ◽  
Aoife Morrin ◽  
Malcolm R. Smyth

2020 ◽  
Vol 22 (15) ◽  
pp. 8157-8163
Author(s):  
Krishnaiah Damarla ◽  
Sanjay Mehra ◽  
Pratap Bahadur ◽  
Debes Ray ◽  
V. K. Aswal ◽  
...  

This article outlines a sustainable method towards the synthesis of advanced materials such as core/shell Quantum Dots (QDs) and their in situ stabilization using microemulsions (MEs).


2014 ◽  
Vol 998-999 ◽  
pp. 111-114
Author(s):  
Hui Liu ◽  
Fang Yan ◽  
Hong Jie Fang ◽  
Li Dong Zhang

Using melamine formaldehyde (MF) microspheres as hard templates and silica colloid as shell precursors, core-shell structures of silica-coated MF microspheres were prepared by the electrostatic adsorption process or spray drying inspired in-situ coating and drying process. Furthermore, nanometer- and micrometer-sized silica hollow spheres were obtained by calcinations in air. The influence of preparation methods and ratio of silica colloid to MF microspheres on the composition, the morphology and size of the core-shell intermediates and the hollow spheres were studied with FTIR, SEM and TEM techniques.


2020 ◽  
Vol 26 (45) ◽  
pp. 5793-5806
Author(s):  
Mazhar Ul-Islam ◽  
Salman Ul-Islam ◽  
Sumayia Yasir ◽  
Atiya Fatima ◽  
Md. Wasi Ahmed ◽  
...  

Biopolymers and their composites have been extensively investigated in recent years for multiple applications, especially in environmental, medical, and pharmaceutical fields. Bacterial cellulose (BC) has emerged as a novel biomaterial owing to its nontoxic, high-liquid absorbing and holding capacity, drug-carrying ability, and pollutant absorbing features. Additionally, its web-shaped three-dimensional (3D) structure and hydrogen bonding sites have incited a combination of various nanoparticles, polymers, and other materials with BC in the form of composites. Such BC-based composites have been developed through in-situ, ex-situ, and solution casting methods for targeted applications, such as air and water filters, controlled drug delivery systems, wound dressing materials, and tissue regeneration. This review details the production and development of BCbased composites with different materials and by various methods. It further describes various applications of BC-based composites in the environmental and pharmaceutical sectors, with specific examples from the recent literature. This review could potentially appeal a wide readership in these two emerging fields, where novel and advanced materials for different applications have been developed on a regular basis using BC as the base material.


2018 ◽  
Vol 83 ◽  
pp. 143-147 ◽  
Author(s):  
Qi Lei Wang ◽  
Xiao Peng Zhang ◽  
Bo Zhi Chen ◽  
Xin Dong Guo

2014 ◽  
Vol 2 (33) ◽  
pp. 6706-6722 ◽  
Author(s):  
Arik Kar ◽  
Amitava Patra

Core–shell structures of SnO2nanocrystals improve the performance of diverse applications.


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