scholarly journals Paper-Based Immunosensors with Bio-Chemiluminescence Detection

Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4309
Author(s):  
Maria Maddalena Calabretta ◽  
Martina Zangheri ◽  
Donato Calabria ◽  
Antonia Lopreside ◽  
Laura Montali ◽  
...  
Keyword(s):  
Everyday Life ◽  
Point Of Care ◽  
Scientific Production ◽  
Considerable Progress ◽  
Routine Analysis ◽  
Ideal Solution ◽  
Unique Combination ◽  
Chemiluminescence Detection ◽  
Open Issues ◽  
Made In

Since the introduction of paper-based analytical devices as potential diagnostic platforms a few decades ago, huge efforts have been made in this field to develop systems suitable for meeting the requirements for the point-of-care (POC) approach. Considerable progress has been achieved in the adaptation of existing analysis methods to a paper-based format, especially considering the chemiluminescent (CL)-immunoassays-based techniques. The implementation of biospecific assays with CL detection and paper-based technology represents an ideal solution for the development of portable analytical devices for on-site applications, since the peculiarities of these features create a unique combination for fitting the POC purposes. Despite this, the scientific production is not paralleled by the diffusion of such devices into everyday life. This review aims to highlight the open issues that are responsible for this discrepancy and to find the aspects that require a focused and targeted research to make these methods really applicable in routine analysis.

PERSEPSI MASYARAKAT DESA SAYANG RW 03 KECAMATAN JATINANGOR KABUPATEN SUMEDANG TERHADAP PENTINGNYA PROTEKSI KENDARAAN BERMOTOR

Dharmakarya ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 145
Author(s):  
Lienda Noviyanti
Keyword(s):  
Everyday Life ◽  
Vehicle Ownership ◽  
Human Needs ◽  
Individual Knowledge ◽  
The Times ◽  
And Behavior ◽  
Motorized Vehicles ◽  
Perception Survey ◽  
Made In ◽  
Lack Of Knowledge

As the times and technology became more sophisticated, human needs and mobility also increased. One such technology is vehicle. It cannot be denied that motorized vehicles and cars have now become the most important parts of everyday life. Vehicle protection is very important to keep vehicles safe, especially in areas prone to theft. Protection of the vehicle itself is divided into two ways, namely by personal and insurance methods. The fact is that vehicle protection carried out by Desa Sayang residents is still very minimal, which is caused by a lack of knowledge and understanding of citizens about the importance of vehicle protection. Seen from only a few residents who have insurance services to protect their vehicles. Measuring the perceptions of residents of RW 03 Desa Sayang, Jatinangor Subdistrict, Sumedang Regency is divided into 2 things, namely knowledge (cognition) and behavior (konasi). Of the 97 informants interviewed, it was found that people's knowledge of insurance was not good. While their knowledge of vehicle protection in general is quite good. In addition, vehicle ownership also affects individual knowledge of insurance and vehicle protection. Unfortunately, protection of vehicles in the form of insurance is rarely done by residents because most are hampered in terms of costs and feel they do not need it. Therefore, a perception survey and vehicle protection socialization were made in Sayang Village, Jatinangor Sub-District, Sumedang Regency so that residents would be more aware of maintaining their vehicles.

Biological Production of (S)-acetoin: A State-of-the-Art Review

2019 ◽  
Vol 19 (25) ◽  
pp. 2348-2356 ◽  
Author(s):  
Neng-Zhong Xie ◽  
Jian-Xiu Li ◽  
Ri-Bo Huang
Keyword(s):  
Side Effects ◽  
Chemical Synthesis ◽  
State Of The Art ◽  
Optically Active ◽  
Considerable Progress ◽  
Future Prospects ◽  
Chiral Compound ◽  
Biological Production ◽  
Acetoin Production ◽  
Made In

Acetoin is an important four-carbon compound that has many applications in foods, chemical synthesis, cosmetics, cigarettes, soaps, and detergents. Its stereoisomer (S)-acetoin, a high-value chiral compound, can also be used to synthesize optically active drugs, which could enhance targeting properties and reduce side effects. Recently, considerable progress has been made in the development of biotechnological routes for (S)-acetoin production. In this review, various strategies for biological (S)- acetoin production are summarized, and their constraints and possible solutions are described. Furthermore, future prospects of biological production of (S)-acetoin are discussed.

scholarly journals III. On the nature and construction of the sun and fixed stars

1795 ◽  
Vol 85 ◽  
pp. 46-72 ◽  
Keyword(s):  
Central Body ◽  
Planetary System ◽  
Considerable Progress ◽  
The Sun ◽  
Great Satisfaction ◽  
The Earth ◽  
The World ◽  
Celestial Bodies ◽  
The Universe ◽  
Made In

Among the celestial bodies the sun is certainly the first which should attract our notice. It is a fountain of light that illuminates the world! it is the cause of that heat which main­tains the productive power of nature, and makes the earth a fit habitation for man! it is the central body of the planetary system; and what renders a knowledge of its nature still more interesting to us is, that the numberless stars which compose the universe, appear, by the strictest analogy, to be similar bodies. Their innate light is so intense, that it reaches the eye of the observer from the remotest regions of space, and forcibly claims his notice. Now, if we are convinced that an inquiry into the nature and properties of the sun is highly worthy of our notice, we may also with great satisfaction reflect on the considerable progress that has already been made in our knowledge of this eminent body. It would require a long detail to enumerate all the various discoveries which have been made on this subject; I shall, therefore, content myself with giving only the most capital of them.

scholarly journals Profile of Brazilian scientific production on A/H1N1 pandemic influenza

2012 ◽  
Vol 17 (6) ◽  
pp. 1629-1634 ◽  
Author(s):  
Adriana Luchs
Keyword(s):  
Impact Factor ◽  
H1n1 Influenza ◽  
Scientific Production ◽  
Similar Amount ◽  
H1n1 Pandemic ◽  
Public Funds ◽  
The Impact ◽  
Journal Impact ◽  
Bibliometric Studies ◽  
Made In

In the last few years, bibliometric studies have proliferated, seeking to provide data on world research. This study analyzes the profile of the Brazilian scientific production in the A (H1N1) influenza field between 2009 and 2011. The research was conducted in MEDLINE, SciELO and LILACS databases, selecting papers in which the term "H1N1" and "Brazil" were defined as the main topics. The data were analyzed taking into consideration the Brazilian state and institution in which the articles were produced, the impact factor of the journal and the language. The research revealed 40 documents (27 from MEDLINE, 16 from SciELO and 24 from LILACS). The journal impact factor ranged from 0.0977 to 8.1230. A similar amount of articles were written in English and Portuguese and São Paulo was the most productive state in the country, with 95% of the Brazilian production originating from the Southern and Southeastern regions. Linguistic data indicate that previous efforts made in order to improve the scientific production of Brazilian researchers making their observations attain a broader scientific audience produced results. It is necessary to assess the scientific studies, especially those conducted with public funds, in order to ensure that the results will benefit society.

Depressive Illnesses in Children and Adolescents: A Review of Current Concepts

1985 ◽  
Vol 30 (2) ◽  
pp. 119-129 ◽  
Author(s):  
B.J. Mcconville ◽  
R.T. Bruce
Keyword(s):  
Children And Adolescents ◽  
Current Knowledge ◽  
Considerable Progress ◽  
Childhood And Adolescence ◽  
Age Related ◽  
Developmental Age ◽  
The Subject ◽  
Made In

Considerable progress has been made in our understanding of depressive illnesses in childhood and adolescence, especially over the last several years. A number of major books on the subject have now appeared, along with a large number of individual papers. This paper attempts to summarize current knowledge, and indicates developmental, age-related and other issues which still require further study.

scholarly journals CONSTITUENT TRANSPORT IN ESTUARIES

1968 ◽  
Vol 1 (11) ◽  
pp. 86 ◽  
Author(s):  
Bard Glenne
Keyword(s):  
Diffusion Process ◽  
Diffusion Coefficients ◽  
Considerable Progress ◽  
Diffusion Method ◽  
Common Application ◽  
Made In ◽  
Mixing And Transport

During the last two decades considerable progress has been made in analyzing the diffusion process in estuaries. Unfortunately, certain difficulties (e g prediction of diffusion coefficients) still prevent common application of the diffusion method An old technique, related to the diffusion concept, can however, frequently give useful information regarding constituent mixing and transport velocities in natural estuaries.

scholarly journals FAZENDO GÊNERO NA EDUCAÇÃO PROFISSIONAL: notas epistemológicas a partir do estado de conhecimento sobre educação profissional e gênero na Biblioteca Digital Brasileira de Teses e Dissertações (2008-2019)

2019 ◽  
Vol 26 (4) ◽  
pp. 235
Author(s):  
Larissa Maia de Souza ◽  
Avelino Aldo de Lima Neto
Keyword(s):  
Digital Library ◽  
Professional Education ◽  
Doctoral Degree ◽  
Gender Issues ◽  
Scientific Production ◽  
The State ◽  
The Subject ◽  
And Gender ◽  
Theses And Dissertations ◽  
Made In

O presente artigo objetiva esboçar algumas considerações epistemológicas acerca das questões de gênero no contexto da produção científica da Educação Profissional. Para tanto, inicialmente, serão feitas algumas provocações ao campo epistêmico em questão a partir de contribuições das teóricas feministas. Em seguida, será mapeada e descrita a quantidade dos trabalhos de pós-graduação disponíveis na Biblioteca Digital Brasileira de Teses e Dissertações cujos objetos tangenciam o assunto, no período de 2008 a 2019. Posteriormente, será explicitado o recurso ao estado do conhecimento como procedimento metodológico para coleta de dados, seguindo-se a apresentação dos resultados. Estes revelaram a existência de apenas treze manuscritos centrados sobre a temática, indicando a escassez de estudos. Face a essa constatação, serão tecidas algumas apreciações finais com vistas a proporcionar à Educação Profissional ferramentas capazes de contribuir para a expansão epistemológica da área e para a continuidade da efetivação de sua proposta político-pedagógica de formação humana integral.Palavras-chave: Gênero. Educação profissional. Epistemologia. Estado do conhecimento. Feminismo.DOING GENDER IN PROFESSIONAL EDUCATION: epistemological notes from the state of knowledge on professional education and gender in the Brazilian Digital Library of Theses and Dissertations (2008-2019)AbstractThis article aims to outline some epistemological considerations about gender issues in the context of the scientific production of Professional Education. To this end, initially, some provocations will be made to the epistemic field in question based on contributions from feminist theorists. Next, it will be mapped and described the amount of master’s and doctoral degree works availables in the Brazilian Digital Library of Theses and Dissertations whose objects tangentiate the subject, in the period from 2008 to 2019. Subsequently, the use of the state of knowledge as a methodological procedure for data collection will be explained, followed by the presentation of the results. These revealed the existence of only thirteen manuscripts centered on the theme, indicating the scarcity of studies. In view of this finding, some final considerations will be made in order to provide Professional Education with tools capable of contributing to the epistemological expansion of the area and to the continuity of the effectiveness of its political-pedagogical proposal of integral human formation.Keywords: Gender. Professional education. Epistemology. State of knowledge. Feminism.HACIENDO GÉNERO EN LA EDUCACIÓN PROFESIONAL: notas epistemológicas a partir del estado del conocimiento sobre educación profesional y género en la Biblioteca Digital Brasileña de Tesis y Disertaciones (2008-2019)ResumenEste artículo tiene por objetivo esbozar algunas consideraciones epistemológicas sobre las cuestiones de género en el contexto de la producción científica de la Educación Profesional. Para eso, inicialmente, se harán algunas provocaciones al campo epistémico en cuestión a partir de las aportaciones de las teóricas feministas. Seguidamente, se mapeará y describirá la cantidad de trabajos de maestría y doctorado disponibles en la Biblioteca Digital Brasileña de Tesis y Disertaciones cuyos objetos tangencializan el tema, en el período de 2008 a 2019. Posteriormente, se explicará el uso del estado del conocimiento como procedimiento metodológico para la recogida de datos, seguido de la presentación de los resultados. Estos revelaron la existencia de sólo trece manuscritos centrados en el tema, lo que indica la escasez de estudios. En vista de este diagnóstico, se harán algunas consideraciones finales para dotar a la Educación Profesional de herramientas capaces de contribuir a la expansión epistemológica del área y a la continuidad de la efectividad de su propuesta político-pedagógica de formación humana integral.Palavras claves: Género. Educación profesional. Epistemología. Estado del conocimiento. Feminismo.

Cosmic y-ray bursts

1981 ◽  
Vol 301 (1462) ◽  
pp. 645-658 ◽  
Keyword(s):  
Temporal Structure ◽  
Considerable Progress ◽  
Large Network ◽  
Exact Location ◽  
Made In ◽  
Arrival Directions

Although y-ray bursts were discovered over ten years ago, the study of their temporal structure, their spectrum and their lg N against lg S distribution have still not enabled scientists to determine their origin. Since 1978, however, considerable progress has been made in the accuracy of locating bursts by triangulation methods, by using a large network of observations made by the Helios B solar-orbiting satellite, the interplanetary spacecraft Pioneer Venus and Venera 11 and 12, ISEE-C and Earth-orbiting satellites. With the great distances between these various measuring points, it can be hoped that an accuracy of the order of one minute of arc will be attained for many events observed in 1979 and 1980. This accuracy has already been surpassed for the March 5, 1979 event. In this paper an analysis of the latest observations, and results on the exact location of the arrival directions of several bursts will be presented, along with the evidence they provide about the origin of this radiation.

Applying lessons learnt from deficiencies in the basel accords to Solvency II

2013 ◽  
Vol 6 (2) ◽  
pp. 309-328
Author(s):  
Johann Jacobs ◽  
Gary Van Vuuren
Keyword(s):  
European Union ◽  
Financial Crisis ◽  
Banking Sector ◽  
Insurance Industry ◽  
Solvency Ii ◽  
Capital Adequacy ◽  
Considerable Progress ◽  
Eu Legislation ◽  
Basel Accords ◽  
Made In

Solvency II is the new European Union (EU) legislation that will review the capital adequacy regime for the insurance industry. Considerable progress has been made in the banking sector with the implementation of the Basel Accords (Basel). The implementation of Solvency II, therefore, brings with it an opportunity for the insurance industry to assess the successes, weaknesses and shortcomings experienced by the banking sector's implementation of Basel so as to learn from them and ensure that Solvency II's implementation duplicates the successes and avoids the failures of Basel's. This article critically explores weaknesses and failures of Basel which were exacerbated and/or exploited by the financial crisis of 2007-2010 and provides advice on how these might be mitigated or avoided in the implementation of Solvency II.

scholarly journals Vitiligo: A Review

Dermatology ◽  
2020 ◽  
Vol 236 (6) ◽  
pp. 571-592 ◽  
Author(s):  
Christina Bergqvist ◽  
Khaled Ezzedine
Keyword(s):  
Autoimmune Disease ◽  
Skin Disorder ◽  
Current Knowledge ◽  
Daily Life ◽  
Considerable Progress ◽  
International Consensus ◽  
Selective Loss ◽  
The Future ◽  
Cosmetic Problem ◽  
Made In

Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5–2% of the population worldwide. The disease is characterized by the selective loss of melanocytes which results in typical nonscaly, chalky-white macules. In recent years, considerable progress has been made in our understanding of the pathogenesis of vitiligo which is now clearly classified as an autoimmune disease. Vitiligo is often dismissed as a cosmetic problem, although its effects can be psychologically devastating, often with a considerable burden on daily life. In 2011, an international consensus classified segmental vitiligo separately from all other forms of vitiligo, and the term vitiligo was defined to designate all forms of nonsegmental vitiligo. This review summarizes the current knowledge on vitiligo and attempts to give an overview of the future in vitiligo treatment.

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