scholarly journals Deep Mining Generation of Lung Cancer Malignancy Models from Chest X-ray Images

Sensors ◽  
2021 ◽  
Vol 21 (19) ◽  
pp. 6655
Author(s):  
Michael Horry ◽  
Subrata Chakraborty ◽  
Biswajeet Pradhan ◽  
Manoranjan Paul ◽  
Douglas Gomes ◽  
...  

Lung cancer is the leading cause of cancer death and morbidity worldwide. Many studies have shown machine learning models to be effective in detecting lung nodules from chest X-ray images. However, these techniques have yet to be embraced by the medical community due to several practical, ethical, and regulatory constraints stemming from the “black-box” nature of deep learning models. Additionally, most lung nodules visible on chest X-rays are benign; therefore, the narrow task of computer vision-based lung nodule detection cannot be equated to automated lung cancer detection. Addressing both concerns, this study introduces a novel hybrid deep learning and decision tree-based computer vision model, which presents lung cancer malignancy predictions as interpretable decision trees. The deep learning component of this process is trained using a large publicly available dataset on pathological biomarkers associated with lung cancer. These models are then used to inference biomarker scores for chest X-ray images from two independent data sets, for which malignancy metadata is available. Next, multi-variate predictive models were mined by fitting shallow decision trees to the malignancy stratified datasets and interrogating a range of metrics to determine the best model. The best decision tree model achieved sensitivity and specificity of 86.7% and 80.0%, respectively, with a positive predictive value of 92.9%. Decision trees mined using this method may be considered as a starting point for refinement into clinically useful multi-variate lung cancer malignancy models for implementation as a workflow augmentation tool to improve the efficiency of human radiologists.

2022 ◽  
Vol 2022 ◽  
pp. 1-12
Author(s):  
Wenfa Jiang ◽  
Ganhua Zeng ◽  
Shuo Wang ◽  
Xiaofeng Wu ◽  
Chenyang Xu

Lung cancer is one of the malignant tumors with the highest fatality rate and nearest to our lives. It poses a great threat to human health and it mainly occurs in smokers. In our country, with the acceleration of industrialization, environmental pollution, and population aging, the cancer burden of lung cancer is increasing day by day. In the diagnosis of lung cancer, Computed Tomography (CT) images are a fairly common visualization tool. CT images visualize all tissues based on the absorption of X-rays. The diseased parts of the lung are collectively referred to as pulmonary nodules, the shape of nodules is different, and the risk of cancer will vary with the shape of nodules. Computer-aided diagnosis (CAD) is a very suitable method to solve this problem because the computer vision model can quickly scan every part of the CT image of the same quality for analysis and will not be affected by fatigue and emotion. The latest advances in deep learning enable computer vision models to help doctors diagnose various diseases, and in some cases, models have shown greater competitiveness than doctors. Based on the opportunity of technological development, the application of computer vision in medical imaging diagnosis of diseases has important research significance and value. In this paper, we have used a deep learning-based model on CT images of lung cancer and verified its effectiveness in the timely and accurate prediction of lungs disease. The proposed model has three parts: (i) detection of lung nodules, (ii) False Positive Reduction of the detected nodules to filter out “false nodules,” and (iii) classification of benign and malignant lung nodules. Furthermore, different network structures and loss functions were designed and realized at different stages. Additionally, to fine-tune the proposed deep learning-based mode and improve its accuracy in the detection Lung Nodule Detection, Noudule-Net, which is a detection network structure that combines U-Net and RPN, is proposed. Experimental observations have verified that the proposed scheme has exceptionally improved the expected accuracy and precision ratio of the underlined disease.


COVID ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 403-415
Author(s):  
Abeer Badawi ◽  
Khalid Elgazzar

Coronavirus disease (COVID-19) is an illness caused by a novel coronavirus family. One of the practical examinations for COVID-19 is chest radiography. COVID-19 infected patients show abnormalities in chest X-ray images. However, examining the chest X-rays requires a specialist with high experience. Hence, using deep learning techniques in detecting abnormalities in the X-ray images is presented commonly as a potential solution to help diagnose the disease. Numerous research has been reported on COVID-19 chest X-ray classification, but most of the previous studies have been conducted on a small set of COVID-19 X-ray images, which created an imbalanced dataset and affected the performance of the deep learning models. In this paper, we propose several image processing techniques to augment COVID-19 X-ray images to generate a large and diverse dataset to boost the performance of deep learning algorithms in detecting the virus from chest X-rays. We also propose innovative and robust deep learning models, based on DenseNet201, VGG16, and VGG19, to detect COVID-19 from a large set of chest X-ray images. A performance evaluation shows that the proposed models outperform all existing techniques to date. Our models achieved 99.62% on the binary classification and 95.48% on the multi-class classification. Based on these findings, we provide a pathway for researchers to develop enhanced models with a balanced dataset that includes the highest available COVID-19 chest X-ray images. This work is of high interest to healthcare providers, as it helps to better diagnose COVID-19 from chest X-rays in less time with higher accuracy.


Author(s):  
Ishtiaque Ahmed ◽  
◽  
Manan Darda ◽  
Neha Tikyani ◽  
Rachit Agrawal ◽  
...  

The COVID-19 pandemic has caused large-scale outbreaks in more than 150 countries worldwide, causing massive damage to the livelihood of many people. The capacity to identify contaminated patients early and get unique treatment is quite possibly the primary stride in the battle against COVID-19. One of the quickest ways to diagnose patients is to use radiography and radiology images to detect the disease. Early studies have shown that chest X-rays of patients infected with COVID-19 have unique abnormalities. To identify COVID-19 patients from chest X-ray images, we used various deep learning models based on previous studies. We first compiled a data set of 2,815 chest radiographs from public sources. The model produces reliable and stable results with an accuracy of 91.6%, a Positive Predictive Value of 80%, a Negative Predictive Value of 100%, specificity of 87.50%, and Sensitivity of 100%. It is observed that the CNN-based architecture can diagnose COVID19 disease. The parameters’ outcomes can be further improved by increasing the dataset size and by developing the CNN-based architecture for training the model.


Author(s):  
Ishtiaque Ahmed ◽  
◽  
Manan Darda ◽  
Neha Tikyani ◽  
Rachit Agrawal ◽  
...  

The COVID-19 pandemic has caused large-scale outbreaks in more than 150 countries worldwide, causing massive damage to the livelihood of many people. The capacity to identify contaminated patients early and get unique treatment is quite possibly the primary stride in the battle against COVID-19. One of the quickest ways to diagnose patients is to use radiography and radiology images to detect the disease. Early studies have shown that chest X-rays of patients infected with COVID-19 have unique abnormalities. To identify COVID-19 patients from chest X-ray images, we used various deep learning models based on previous studies. We first compiled a data set of 2,815 chest radiographs from public sources. The model produces reliable and stable results with an accuracy of 91.6%, a Positive Predictive Value of 80%, a Negative Predictive Value of 100%, specificity of 87.50%, and Sensitivity of 100%. It is observed that the CNN-based architecture can diagnose COVID-19 disease. The parameters’ outcomes can be further improved by increasing the dataset size and by developing the CNN-based architecture for training the model.


2022 ◽  
Vol 2161 (1) ◽  
pp. 012078
Author(s):  
Pallavi R Mane ◽  
Rajat Shenoy ◽  
Ghanashyama Prabhu

Abstract COVID -19, is a deadly, dangerous and contagious disease caused by the novel corona virus. It is very important to detect COVID-19 infection accurately as quickly as possible to avoid the spreading. Deep learning methods can significantly improve the efficiency and accuracy of reading Chest X-Rays (CXRs). The existing Deep learning models with further fine tune provide cost effective, rapid, and better classification results. This paper tries to deploy well studied AI tools with modification on X-ray images to classify COVID 19. This research performs five experiments to classify COVID-19 CXRs from Normal and Viral Pneumonia CXRs using Convolutional Neural Networks (CNN). Four experiments were performed on state-of-the-art pre-trained models using transfer learning and one experiment was performed using a CNN designed from scratch. Dataset used for the experiments consists of chest X-Ray images from the Kaggle dataset and other publicly accessible sources. The data was split into three parts while 90% retained for training the models, 5% each was used in validation and testing of the constructed models. The four transfer learning models used were Inception, Xception, ResNet, and VGG19, that resulted in the test accuracies of 93.07%, 94.8%, 67.5%, and 91.1% respectively and our CNN model resulted in 94.6%.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Makoto Nishimori ◽  
Kunihiko Kiuchi ◽  
Kunihiro Nishimura ◽  
Kengo Kusano ◽  
Akihiro Yoshida ◽  
...  

AbstractCardiac accessory pathways (APs) in Wolff–Parkinson–White (WPW) syndrome are conventionally diagnosed with decision tree algorithms; however, there are problems with clinical usage. We assessed the efficacy of the artificial intelligence model using electrocardiography (ECG) and chest X-rays to identify the location of APs. We retrospectively used ECG and chest X-rays to analyse 206 patients with WPW syndrome. Each AP location was defined by an electrophysiological study and divided into four classifications. We developed a deep learning model to classify AP locations and compared the accuracy with that of conventional algorithms. Moreover, 1519 chest X-ray samples from other datasets were used for prior learning, and the combined chest X-ray image and ECG data were put into the previous model to evaluate whether the accuracy improved. The convolutional neural network (CNN) model using ECG data was significantly more accurate than the conventional tree algorithm. In the multimodal model, which implemented input from the combined ECG and chest X-ray data, the accuracy was significantly improved. Deep learning with a combination of ECG and chest X-ray data could effectively identify the AP location, which may be a novel deep learning model for a multimodal model.


2021 ◽  
pp. 303-312
Author(s):  
Siddharth Gupta ◽  
Palak Aggarwal ◽  
Sumeshwar Singh ◽  
Shiv Ashish Dhondiyal ◽  
Manisha Aeri ◽  
...  

2020 ◽  
Vol 7 ◽  
Author(s):  
Seung Hoon Yoo ◽  
Hui Geng ◽  
Tin Lok Chiu ◽  
Siu Ki Yu ◽  
Dae Chul Cho ◽  
...  

2021 ◽  
Vol 11 (21) ◽  
pp. 10301
Author(s):  
Muhammad Shoaib Farooq ◽  
Attique Ur Rehman ◽  
Muhammad Idrees ◽  
Muhammad Ahsan Raza ◽  
Jehad Ali ◽  
...  

COVID-19 has been difficult to diagnose and treat at an early stage all over the world. The numbers of patients showing symptoms for COVID-19 have caused medical facilities at hospitals to become unavailable or overcrowded, which is a major challenge. Studies have recently allowed us to determine that COVID-19 can be diagnosed with the aid of chest X-ray images. To combat the COVID-19 outbreak, developing a deep learning (DL) based model for automated COVID-19 diagnosis on chest X-ray is beneficial. In this research, we have proposed a customized convolutional neural network (CNN) model to detect COVID-19 from chest X-ray images. The model is based on nine layers which uses a binary classification method to differentiate between COVID-19 and normal chest X-rays. It provides COVID-19 detection early so the patients can be admitted in a timely fashion. The proposed model was trained and tested on two publicly available datasets. Cross-dataset studies are used to assess the robustness in a real-world context. Six hundred X-ray images were used for training and two hundred X-rays were used for validation of the model. The X-ray images of the dataset were preprocessed to improve the results and visualized for better analysis. The developed algorithm reached 98% precision, recall and f1-score. The cross-dataset studies also demonstrate the resilience of deep learning algorithms in a real-world context with 98.5 percent accuracy. Furthermore, a comparison table was created which shows that our proposed model outperforms other relative models in terms of accuracy. The quick and high-performance of our proposed DL-based customized model identifies COVID-19 patients quickly, which is helpful in controlling the COVID-19 outbreak.


Sign in / Sign up

Export Citation Format

Share Document