scholarly journals Anti-Aging Effects of Terminalia bellirica, Phyllanthus emblica, Triphala, and Carica papaya Extracts for Sustainable Youth

2022 ◽  
Vol 14 (2) ◽  
pp. 676
Author(s):  
Mijeong Choi
Keyword(s):  
Antibacterial Activity ◽  
Side Effects ◽  
Research And Development ◽  
Carica Papaya ◽  
Phyllanthus Emblica ◽  
Aging Effects ◽  
Flavonoid Content ◽  
Solid Mixture ◽  
Human Lifespan ◽  
Terminalia Bellirica

As the human lifespan becomes longer, many people invest time and money in managing external beauty. However, managing external beauty has the disadvantage of causing side effects or that the effect does not last. Therefore, research and development are required to maximize effectiveness, eco-friendliness, and sustainably in beauty management. The purpose of this study was to experimentally identify the anti-aging effects, such as skin wrinkle and elasticity improvement, of extracts from Bahera, Phyllanthus emblica, Triphala, and Carica papaya, and to confirm their development as whitening and wrinkle functional cosmetic materials. In this study, a solid mixture was prepared using eco-friendly Terminalia bellirica, amla (Phyllanthus emblica), Triphala, and Carica papaya, and experimental samples were extracted. Antioxidant tests, antibacterial activity tests, polyphenol and flavonoid content, and deodorization tests were conducted to test the efficacy of experimental samples. The procedures and methods of these experiments are summarized in the following article. In this study, we found that the Bahera, Phyllanthus emblica, Triphala, and Carica papaya extracts had significant effects on whitening and wrinkle improvement, and that the effects of using ethanol-based extracts as the co-solvent were even greater. In other words, extracts of Bahera, Phyllanthus emblica, Triphala and Carica papaya showed antioxidant, whitening, and anti-wrinkle effects, and extracts that used ethanol as a co-solvent showed greater effects. In particular, we found that the optimal concentration of ethanol as a co-solvent maximizes its effectiveness at 70%.

scholarly journals Antibacterial Activity and Flavonoids Content of Artemisia cina Berg. ex Poljakov Ethyl Acetate Extracts

2021 ◽  
Vol 13 (1) ◽  
pp. 106-112
Author(s):  
Sri Kasmiyati ◽  
Elizabeth Betty Elok Kristiani ◽  
Maria Marina Herawati ◽  
Andreas Binar Aji Sukmana
Keyword(s):  
Antibacterial Activity ◽  
Medicinal Plant ◽  
Ethyl Acetate ◽  
Biological Activities ◽  
Diffusion Method ◽  
Gram Negative Bacteria ◽  
Flavonoid Content ◽  
Gram Positive ◽  
Gram Negative ◽  
Significant Difference

The medicinal plant-derived bioactive compounds have a potential for many biological activities, including antimicrobial activity. Artemisia cina is a medicinal plant from the Compositae family with the potential of having antitumor, antifungal, and antibacterial activity. This study aimed to determine the antibacterial activity and the flavonoid content of A. Cina’s ethyl acetate extract. Plants samples were extracted by ethyl acetate maceration method. Antibacterial activity was tested against Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) by a disk diffusion method using 25, 50, and 100 mg/l extract concentrations. The flavonoid contents (quercetin and kaempferol) were measured using High-Performance Liquid Chromatography. The extracts of diploid and polyploid A. cina displayed some antibacterial activity, with the Gram-negative bacteria being more resistant than the Gram-positive counterpart. However, no significant difference was observed between the diploid and polyploid extracts. As for the flavonoid content, the highest quercetin content (0.5501 mg/ml) was found in the polyploid A. cina (J), while the highest kaempferol content (0.5818 mg/ml) was observed in the diploid A. cina (KJT). Although A. cina is widely grown in Indonesia, compared to other Artemisia species, A. cina has not been widely studied, especially its antibacterial  potential and in related to its flavonoid content and the use of ethyl acetate as the extraction solvent.  This study reveals the potential of A. cina as a natural antibacterial agent. 

Antimicrobial Applications of Nanoparticles

2022 ◽  
pp. 269-288
Author(s):  
Ayesha Kanwal ◽  
Zeeshan Ahmad Bhutta ◽  
Ambreen Ashar ◽  
Ashar Mahfooz ◽  
Rizwan Ahmed ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Side Effects ◽  
Antibacterial Agent ◽  
Antibacterial Agents ◽  
The Other ◽  
Drug Resistant ◽  
Short Term ◽  
Human Mortality ◽  
Recent Developments

Human mortality due to drug-resistant infections is becoming more prevalent in our society. Antibiotics are impotent due to abuse and/or misuse, leading to new, more expensive, and more effective medicines and treatments. Therefore, it causes many short-term and long-term side effects in the patient. On the other hand, nanoparticles have exhibited antibacterial activity against various pathogens due to their small size and ability to destroy cells by various mechanisms. Unlike antibiotics for the treatment of patients' diseases and infections, nanomaterials provide an exciting way to limit the growth of microorganisms due to infections in humans. This has led to the development of a number of nanoparticles as active antibacterial agents. Therefore, the authors have carefully reviewed the recent developments in the use of nanomaterials for antibacterial applications and the mechanisms that make them an effective alternate antibacterial agent.

ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF RUTA ANGUSTIFOLIA EXTRACT

2015 ◽  
Vol 77 (25) ◽  
Author(s):  
Nur Azfa Shuib ◽  
Anwar Iqbal ◽  
Fatimatul Akmal Sulaiman ◽  
Izzatie Razak ◽  
Deny Susanti
Keyword(s):  
Antibacterial Activity ◽  
Phenolic Content ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Diffusion Method ◽  
Total Phenolic ◽  
Disc Diffusion ◽  
Flavonoid Content ◽  
Disc Diffusion Method ◽  
Polyphenolic Content

Ruta angustifolia was used in this study in order to evaluate the antimicrobial activity and antioxidant properties and its correlation with the polyphenolic content. Two Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778) and two Gram–negative bacteria (Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 8739) were used to determine the antibacterial activity. Aqueous maceration extract was used for antioxidant activities and methanolic maceration extract was used for antibacterial activity. The antioxidant properties and activities were evaluated by using total phenolic content (TPC), total flavonoid content (TFC), DPPH free radical scavenging activity and beta-carotene bleaching method. Whereas, the antibacterial activity was examined using disc diffusion method against selected microorganism at concentration 1.0 mg/disc. The results showed the phenolic content of R. angustifolia extract was 18.89 g GAE/100 g extract while the flavonoid content was 14.170 g QE/100 g extract. R. angustifolia exhibited good radical scavenging with IC50 value of 2.04 mg/ml. The result for disc diffusion method showed no inhibition zone against all the strains of bacteria at 1.0 mg/disc concentration of the extract. Based on the results, it can be concluded that the R. angustifolia aqueous extract has the antioxidant properties and there is correlation between polyphenolic content of the extract with its antioxidant activity. However, R. angustifolia methanolic extract did not show any antibacterial activity.

A New Approach to the Classification of Filamemts of Rejuvenascence of Skin of Face and Neck

10.12737/5011 ◽  
2014 ◽  
Vol 21 (2) ◽  
pp. 104-109 ◽  
Author(s):  
Кодяков ◽  
A. Kodyakov ◽  
Груздев ◽  
D. Gruzdev ◽  
Федоров ◽  
...  
Keyword(s):  
Side Effects ◽  
Evaluation Criteria ◽  
Aging Effects ◽  
Actual Problem ◽  
New Approach ◽  
Negative Appraisal ◽  
Minimum Number ◽  
Definition Of

This paper is devoted to the actual problem of cosmetology - the procedures of filament rejuvenation of face and neck, which become popular every year. Literature data on the efficacy of these methods are controversial. The authors of most works indicate the minimum number of complications in the practical absence of negative appraisal methodology. The issues of development of the indication for use of some types of filaments and optimal criteria of evaluation of the expected effect in clinical practice are relevant and are discussed in this paper. Taking into account the absence of objective information about long-term consequences, other practical aspects of filament rejuvenation, the authors on the basis of many years of research and experience has specified evaluation criteria and suggested own classification of cosmetic filaments used in the method of filament rejuvenation of face and neck. Installation of filaments with different cosmetic features allows to reaching three different anti-aging effects: lifting, reinforcing and bio-stimulation. The degree of manifestation of these effects depends on the installation method of the thread, but first of all - on the design of conductive filament and needle or cannula. Based on the above data, the authors propose to divide all known cosmetic filaments on the basis of their purpose, proceeding from the achieved effect for three species - lifting, reinforcing and bio-stimulating. The new classification can be used in practice to optimize the selection of filaments for rejuvenation of face and neck and to reduce unintended side effects. The proposed classification of filaments has the purpose of definition of a fundamental criterion for their beauty opportunities. The practical application of this classification contributes to ensure adequate choice of filaments to perform the procedure, reduce side effects and create realistic expectations of doctors and patients from the procedures of the rejuvenation of face and neck.

scholarly journals Determination of Biological Activities of the Root Bark of Senna singueana

2020 ◽  
pp. 25-34
Author(s):  
Kidanemariam Teklay Hilawea ◽  
Zelalem Yibralign Desta
Keyword(s):  
Antibacterial Activity ◽  
Biological Activities ◽  
Total Flavonoid ◽  
Diffusion Method ◽  
Total Phenolic ◽  
Phytochemical Analysis ◽  
Root Bark ◽  
Total Flavonoid Content ◽  
Flavonoid Content

Aims: Senna singueana is a medicinal plant which is used for the treatment of different kinds of diseases and the plant was selected for the study because of its numerous uses. The main objective of this study was to determine the antioxidant and antibacterial activity of the extracts of the root barks of S. singueana. Methodology: The antibacterial activities of the extracts (determination of Minimal Inhibitory “MIC” and Minimal Bactericidal Concentration “MBC”) were determined by using agar well diffusion method. In addition to this the total flavonoid and total phenolic contents were determined by using aluminum chloride colorimetric complex assay and Folin-Ciocalteu method respectively. Results: Our results revealed that the total flavonoid content of the extracts is ranged from 30.39 mgQE/100 g to 240.83 mgQE/100 g. The extracts also showed good antioxidant activity and total phenolic content as well as weak to moderate antibacterial activity against some bacteria. Conclusions: The extracts of the root bark of Senna sinueana showed good total flavonoid content, DPPH radical scavenging activity and antibacterial activity. In addition to this, the extracts also showed the presence of some important compounds by phytochemical analysis.

scholarly journals Ayurvedic Amalaki Rasayana promotes improved stress tolerance and thus has anti-aging effects in Drosophila melanogaster

2016 ◽  
Author(s):  
Vibha Dwivedi ◽  
Subhash C. Lakhotia
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Drosophila Melanogaster ◽  
Stress Tolerance ◽  
Healthy Aging ◽  
Phyllanthus Emblica ◽  
Wild Type ◽  
Aging Effects ◽  
Sod Activity ◽  
Normal Food

AbstractEthnopharmacological relevanceAmalaki Rasayana (AR) is a common Ayurvedic herbal formulation of Phyllanthus emblica fruits and other ingredients and is used for general good health and healthy aging. We earlier reported it to improve life history traits and to suppress neurodegeneration as well as induced apoptosis in Drosophila.Aim of the studyTo examine effects of dietary AR supplement on cell stress responses in Drosophila melanogaster.Materials and methodsLarvae/flies, reared on normal food or on that supplemented with 0.5% (w/v) AR, were exposed to crowding, thermal or oxidative stress and examined for survival, stress tolerance and levels of lipid peroxides, SOD and HSPs.ResultsWild type larvae/flies reared on AR supplemented food survived the various cell stresses much better than those reared on normal food. AR-fed mutant park13 or DJ-1βDelta93 (Parkinson’s disease model) larvae, however, showed only partial or no protection, respectively, against paraquat-induced oxidative stress, indicating essentiality of DJ-1β for AR mediated oxidative stress tolerance. AR feeding reduced the accumulation of reactive oxygen species (ROS) and lipid peroxidation even in aged (35 day old) wild type flies while enhancing superoxide dismutase (SOD) activity. We show for the first time that while Hsp70 or Hsp83 expression under normal or stress conditions was not differentially affected by AR feeding, Hsp27 levels were elevated in AR fed wild type control as well as heat shocked larvae. Therefore, besides the known anti-oxidant activity of Phyllanthus emblica fruits, dietary AR also enhances cellular levels of Hsp27.ConclusionIn the context of the reported “anti-aging” and “healthy-aging” effects of AR, the present in vivo study on a model organisms shows that AR feeding significantly improves tolerance to a variety of cell stresses through reduced ROS and lipid peroxidation and enhanced SOD activity and Hsp27. Such improved cellular defences following dietary AR provide better homeostasis and thereby improve the life-span and quality of organism’s life.

scholarly journals Antibacterial activities and phytochemical screening of crude extract of Carica papaya leaf against selected pathogens

2020 ◽  
Vol 26 (2) ◽  
pp. 165-170
Author(s):  
A.E. Ajiboye ◽  
R.A. Olawoyin
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Klebsiella Pneumoniae ◽  
Aqueous Extract ◽  
Carica Papaya ◽  
Antibacterial Activities ◽  
Phytochemical Screening ◽  
Zone Of Inhibition ◽  
Crude Extracts ◽  
Test Organisms

Carica papaya commonly known as paw paw belongs to the family of Curcubitaceae and commonly grown in tropical regions. It possesses  antimicrobial, antihelmintic and antioxidant properties. The study assessed the antibacterial potency of Carica papaya against Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus. Acetone and aqueous extracts of the leaves of Carica papaya were obtained using standard methods. The antibacterial activity of the extracts was done using agar well diffusion methods. The Minimum inhibitory and Minimum bactericidal concentrations were done using standard procedures. The antibacterial activities of the crude extracts of Carica papaya against the test organisms revealed that acetone extract showed maximum zone of inhibition on Staphylococcus aureus with a diameter of 17.90±0.10mm at 500 mg/ml and the lowest inhibitory effect on Klebsiella pneumoniae with a zone of 6.50±0.50mm at 100 mg/ml, the aqueous extract showed maximum zone of  inhibition on Staphylococcus aureus with a diameter of 15.50±0.50mm at 500 mg/ml and the lowest zone of inhibition was on Staphylococcus aureus with a diameter of 6.50±0.50mm at 100 g/ml. The Minimum Inhibitory Concentration of acetone and aqueous extract was 40 mg/ml and 50mg/ml against Klebsiella pneumoniae respectively. The Minimum Bactericidal Concentration of the extracts ranges from 40-60mg/ml. The qualitative  phytochemical screening result revealed the presence of tannins, saponnin, alkaloids and steroid. The quantitative phytochemicals revealed 0.70%  of flavonoids, 0.48% of alkaloids, 1.02% of tannin, 0.11% of steroids and 1.08% of glycoside. The result obtained revealed that crude extracts of Carica papaya leaves has antibacterial activities against the test organisms. Keywords: Carica papaya, Phytochemical screening, Pathogens, Antibacterial  activity

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