scholarly journals A Case of Submandibular Leiomyosarcoma, Mimicking an Abscess, in a Ball Python (Python regius)

2021 ◽  
Vol 8 (10) ◽  
pp. 224
Author(s):  
Jun Kwon ◽  
Sang Wha Kim ◽  
Sang Guen Kim ◽  
Hyoun Joong Kim ◽  
Sung Bin Lee ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Postoperative Recovery ◽  
Bacterial Cells ◽  
Lung Involvement ◽  
Fine Needle ◽  
Python Regius ◽  
Immunohistochemistry Analysis ◽  
Gross Examination

A two-year-old ball python with a submandibular mass was evaluated. Fine needle aspiration resulted in debris containing purulent materials and bacterial cells on cytology. Radiography demonstrated multi-focal radiopaque lesions in the mass, which were suspected to be mineralization; there was an absence of mandibular invasion or lung involvement. Gross examination of the surgically excised mass revealed a multi-nodular, well-circumscribed lesion with purulent material. The postoperative recovery was uneventful. The histopathological examination followed by immunohistochemistry analysis gave a diagnosis of leiomyosarcoma. As tumors containing purulent materials can be confused with an abscess, diagnostic confirmation with various diagnostical tools should be considered.

scholarly journals Pleomorphic Adenoma of the Submandibular Gland in a 10-Year-Old Child: A Case Report

2021 ◽  
pp. 014556132110221
Author(s):  
Bouatay Rachida ◽  
Ons Kharrat ◽  
Wiem Boughzala ◽  
Seifeddine Ben Hammouda ◽  
Nouha Ben Abdeljelil ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Pleomorphic Adenoma ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Preoperative Evaluation ◽  
Needle Aspiration ◽  
Magnetic Resonance Images ◽  
Fine Needle ◽  
Sebaceous Cyst ◽  
Growing Mass

We report the case of a 10-year-old girl with a painless slowly growing mass that had developed over the course of 2 years in the left submandibular area. Physical examination revealed a firm painless submandibular mass with no other associated signs. Ultrasound graphics were in favor of a sebaceous cyst. Fine-needle aspiration and magnetic resonance images (MRI) concluded to a pleomorphic adenoma of the submandibular gland. The patient underwent left submandibulectomy. Histopathological examination confirmed the diagnosis of pleomorphic adenoma arising from the submandibular gland. The postoperative course was uneventful. Pleomorphic adenoma of the submandibular gland represents a diagnostic and therapeutic dilemma in children. Preoperative evaluation, including MRI and fine-needle aspiration, is recommended. Total submandibulectomy is also recommended to minimize recurrences and to avoid malignant transformation.

The Association of “GOOP” on Gross Examination of Fine Needle Aspiration Samples and On-Site Adequacy

Respiration ◽  
2021 ◽  
pp. 1-4
Author(s):  
Nikhil Meena ◽  
Thaddeus Bartter ◽  
Roshen Mathew ◽  
Abhishek Kumar ◽  
Winnie Elma Roy ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Study Interval ◽  
White Material ◽  
Gross Examination ◽  
Malignant Diagnosis ◽  
Rule Out

<b><i>Background:</i></b> Rapid on-site cytologic evaluation (ROSE) is not always available for fine needle aspiration (FNA) specimens. We have examined the relationships between the presence of “GOOP” (defined as gooey white material) on FNA aspirates, on-site adequacy (OSA), and diagnosis. <b><i>Methods:</i></b> Consecutive FNA samples obtained over the study interval were included. Samples were assessed macroscopically for the presence or absence of GOOP (GOOP+ or GOOP−). GOOP+ samples were further characterized as shiny (G+<sub>S</sub>) or cheesy (G+<sub>C</sub>). Gross descriptors were correlated with OSA and final diagnoses. <b><i>Results:</i></b> Of the 204 sites biopsied, 102 were malignant, 94 benign, and 8 nondiagnostic. The presence of GOOP was highly predictive for adequacy (positive predictive value 98%). While these correlations for GOOP positivity were significant, the absence of GOOP did not rule out adequacy or malignancy. The presence of GOOP was also significantly correlated with a malignant diagnosis. <b><i>Conclusions:</i></b> We have prospectively demonstrated that the presence of GOOP correlates strongly with adequacy. This may be of value for those for whom ROSE is not available and, when available, may help prioritize specimens for on-site review.

scholarly journals Cysticercosis: Hooked by a Hooklet on Fine Needle Aspiration Cytology—A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-2 ◽  
Author(s):  
Manav Sawhney ◽  
Shubhra Agarwal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Bladder Wall ◽  
Clinical Manifestations ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Muscle Involvement ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Cysticercosis is a systemic parasitic disease caused by the larval form of cestodeT. solium. It has a worldwide distribution and is potentially harmful with variable clinical manifestations. The patient most commonly presents with subcutaneous and muscle involvement in the form of nodular lesions. The other most commonly involved sites include eye, brain, bladder wall, and heart. Cysticercosis can be diagnosed on serology, and radiologically but confirmatory diagnosis is based on histopathological examination of the involved tissue biopsy specimen. Fine needle aspiration cytology is a useful low-cost outpatient procedure tool for preoperative diagnosis of cysticercosis and is absolutely essential for diagnosis of the parasitic lesions in a peripheral hospital, one like ours.

scholarly journals Cytohistological Concordance of Papillary Carcinoma of Thyroid and Its Variants

2021 ◽  
Vol 8 (04) ◽  
pp. 213-218
Author(s):  
Nameera Saleem ◽  
Naval Kishore Bajaj ◽  
Ezhil Arasi Nagamuthu
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Papillary Carcinoma ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Correct Diagnosis ◽  
Needle Aspiration ◽  
Papillary Thyroid ◽  
Fine Needle ◽  
Nuclear Features

BACKGROUND Papillary thyroid carcinoma is the most common malignancy of the thyroid gland. Fine Needle Aspiration Cytology (FNAC) is a rapid, safe and economic procedure, and has a sensitivity approaching of 93.5 % and specificity close to 90 % for diagnosing papillary thyroid carcinomas. This study aims at correlating the cytological and histological diagnosis to arrive at the rate of concordance and discordance, identify variants of papillary thyroid carcinoma (PTC) on cytology and discuss the cytological mimics of PTC. METHODS Data from cases was collected over a period of three years (2015 - 2018). A descriptive study was done. Cases from Osmania General Hospital representing histologically proven cases of papillary carcinoma thyroid along with their corresponding cytological findings were analysed. Cytosmears were obtained from fine needle aspiration of thyroid lesions using a 26-gauge needle, stained with haematoxylin and eosin (H&E). Thyroidectomy specimens were fixed in 10 % buffered formalin, grossed and paraffin embedded. After processing, sections obtained by microtomy were stained with H & E for histopathologic evaluation. RESULTS The institute received a total of 258 thyroid specimens for histopathology and 686 cases for thyroid FNAC over a period of three years. This study includes 70 cases which had both cytology and histopathology correlation at our institution. 65 cases were diagnosed as PTC on histopathology and correct diagnosis was made on cytology with 73.8 % concordance (48 / 65 cases) and discordance was seen in 26.1 % (17 / 65 cases). 5 cases were misdiagnosed on cytology as PTC, and on histopathological examination were diagnosed as non-PTC. CONCLUSIONS Fine needle aspiration shows variable accuracy for PTC, ranging from 65 % to 90 %. The architectural arrangement of cells in papillary fragments and presence of nuclear features in majority of cells is diagnostic of the conventional variant of PTC. The other variants however, pose a diagnostic dilemma on account of their architectural variation, altered cytomorphology and the scant presence of nuclear features. An increase in the awareness of cytomorphology of variants and also of the mimics of PTC helps improve the diagnostic accuracy on FNAC. KEYWORDS Papillary Thyroid Carcinoma, Variants of PTC, Cytohistopathological Correlation

scholarly journals SPOROTRIKOSIS LIMFOKUTAN DIAGNOSIS HISTOPATOLOGI DAN SITOLOGI

2013 ◽  
Vol 2 (1) ◽  
Author(s):  
Poppy M. Lintong ◽  
Inneke V. Sumolang
Keyword(s):  
Skin Lesion ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Histopathological Examination ◽  
Sporothrix Schenckii ◽  
Giant Cells ◽  
Skin Lesions ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Left Hand

Abstract: Diagnosis of sporotrichosis associated with lymphocutaneous nodules was made based on the histopathological examination of skin lesions and the cytology of fine needle aspiration biopsy (FNAB). A case of sporotrichosis in a 63-year-old man was reported with papules and nodules spread along the back of the left hand, forearm, and arm. The histopatho-logical examination showed infiltration of PMNs, granulomas, and giant cells in the dermis and epidermis, along with hyperplasia and microabscesses. Sporothrix schenckii was not found in the skin lesion tissues. However, in the FNAB cytology examination of lymphocutaneus nodules we found spores of Sporothrix schenckii in the cytoplasma of histiocytes besides granuloma and infiltration of PMNs. Key words: sporothrix schenckii, histopathology, FNAB cytology.  Abstrak: Diagnosis sporotrikosis kulit dengan nodul limfokutan ditegakkan melalui pemerik-saan histopatologi pada lesi kulit dan sitologi biopsi aspirasi jarum halus pada nodul limfo-kutan. Kami melaporkan kasus sporotrikosis pada laki-laki berusia 63 tahun dengan papul-papul dan nodul-nodul eritematosa pada dorsum manus, antebrakium, dan brakium sinistra. Pemeriksaan histopatologi jaringan biopsi dari lesi kulit menunjukkan reaksi radang, gambaran granuloma, dan sel datia dalam dermis dan epidermis, dengan mikroabses disertai hiperplasia. Tidak ditemukan jamur Sporothrix schenckii dalam potongan jaringan histopatologi. Hasil pemeriksaan sitologi biopsi aspirasi jarum halus pada nodul limfokutan memperlihatkan adanya spora-spora jamur Sporothrix schenckii dalam sitoplasma sel-sel histiosit disamping  terdapatnya bentuk granuloma dalam infiltrat radang. Kata kunci: sporothrix schenckii, histopatologi, sitologi biopsi aspirasi jarum halus.

scholarly journals Clinicopathological study of thyroid swellings

2020 ◽  
Vol 6 (5) ◽  
pp. 974
Author(s):  
Anchal Gupta ◽  
Padam Singh Jamwal
Keyword(s):  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Clinical Problem ◽  
Neck Surgery ◽  
Needle Aspiration ◽  
Functional Abnormality ◽  
Fine Needle ◽  
Common Diagnosis ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

<p class="abstract"><strong>Background:</strong> Diseases of the thyroid continue to be a common clinical problem having a prevalence rate of 4 to 7% in the general population.</p><p class="abstract"><strong>Methods:</strong> This retrospective study was conducted in the Department of ENT, Head and Neck Surgery, SMGS Hospital, Jammu from January 2018 to January 2020. A thorough history taking, meticulous clinical examination, routine hematological and biochemical investigations were done in all the patients. General examination of the patient was done and looked for thyroid functional abnormality followed by local examination was carried out to locate and identify the site of the swelling, shape, size and consistency of the thyroid swelling and clinical diagnosis was made. All thyroid swelling cases were subjected to fine needle aspiration cytology (FNAC). The type of thyroidectomy is based on the size and type of thyroid whether neoplastic or non-neoplastic. All the specimens were sent for histopathological examination.  </p><p class="abstract"><strong>Results:</strong> Out of 60 patients in the study, 56 were females and only 4 were males. The most common age group was 31 to 40 years seen in 24 (40%) patients. The most common presenting symptom was swelling in the neck seen in 58 (96.67%) patients. The most common diagnosis on FNAC was colloid goiter seen in 40 (66.67%) patients. The most common was benign nodular colloid goiter seen in 35 (58.33%) patients.</p><p class="abstract"><strong>Conclusions:</strong> Fine needle aspiration is a very useful and indispensible test in the diagnosis of thyroid lesions.</p>

scholarly journals A case report of 29 year old male patient with breast carcinoma: diagnosed on fine needle aspiration cytology

2019 ◽  
Vol 8 (1) ◽  
pp. 375
Author(s):  
Komal Patel ◽  
Pallavi Chaudhri ◽  
Siddhi M. Patel
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Male Breast ◽  
Breast Cancers ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
The Mean ◽  
Needle Aspiration Cytology

Breast cancer has been considered a female dominated disease. Carcinoma of male breast is a rare disease representing 1% of all breast cancers and less than 1 % of all cancers in men. The mean age at presentation is mainly in sixties. We here present a case of male breast cancer presented at very young age of 29 years, diagnosed on fine needle aspiration which was confirmed later on histopathological examination.

scholarly journals Fine needle aspiration cytology in feline skeletal muscle as a diagnostic tool for extramedullary plasmacytoma

2017 ◽  
Vol 69 (3) ◽  
pp. 587-592
Author(s):  
D.B. Martins ◽  
C.K. Rossato ◽  
S.L. Silva ◽  
S.S.N. Almeida ◽  
L.S. Ribeiro
Keyword(s):  
Skeletal Muscle ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Extramedullary Plasmacytoma ◽  
Feline Leukemia Virus ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

ABSTRACT Extramedullary noncutaneous plasmacytoma (ENP) is a myeloproliferative disorder of plasma cells that rarely affects cats. This paper describes an ENP case revealed by fine needle aspiration cytology (FNAC) of the mass in the skeletal muscle of an 8-month-old, male, mixed breed cat, which had a nodule in the left hind limb. The rapid immunoassay test confirmed the presence of feline leukemia virus (FeLV). The animal necropsy macroscopically showed the nodule came from the semimembranosus muscle. Histopathological examination ratified the cytological findings. Thus, this paper alerts to the existence of plasmacytoma located in the skeletal muscle of feline species. FNAC is a quick and efficient method for diagnosis of ENP.

scholarly journals Transesophageal endoscopic ultrasound fine needle aspiration of vertebral body osteolytic tumors – a novel diagnostic approach. Case series.

2020 ◽  
Author(s):  
Romeo Ioan Chira ◽  
Alina Florea ◽  
Vlad Ichim ◽  
Liliana Rogojan ◽  
Alexandra Chira ◽  
...  
Keyword(s):  
Vertebral Body ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Traditional Approach ◽  
Case Series ◽  
Lumbar Vertebrae ◽  
Needle Aspiration ◽  
Ct Guided ◽  
Fine Needle

Aims: Vertebral lesions, either primary or more frequently metastasis, are difficult targets for percutaneous guided biopsies and surgical biopsies and are associated with greater risks of complications. We investigated the feasibility of endoscopic ultrasound (EUS) fine needle aspiration (FNA) biopsy in the assessment of vertebral osteolytic tumors as an alternative to CT guided biopsy which is the technique currently used.Material and methods: Four patients with osteolytic tumors of the vertebral bodies identified by imaging methods (CT or MRI) – 3 patients, and one with a tumor detected primarily during EUS procedure were included in order to evaluate the feasibility of the procedure. The lesions were located either at the dorsal or lumbar vertebrae. In all cases we performed EUS FNA of the osteolytic vertebral body lesions with 22G needles using the transesophageal or transgastric approach.Results: In all cases EUS FNA provided enough tissue for an accurate histopathological report, with no procedural complication. We diagnosed lung adenocarcinoma, hepatocarcinoma and a pancreatic adenocarcinoma vertebral metastasis and one case of lymphoma.Conclusions: EUS FNA is a valuable technique which should be considered in selected cases, when a “traditional approach” is not applicable or associated with a higher risk. Treatment guidelines are based on the histology of the tumor, histopathological examination being nowadays mandatory. Therefore, we propose for selected cases a feasible technique, with significantly lower procedural risks, as an alternative for open surgical biopsies or computed tomography guided biopsies

Sign in / Sign up

Export Citation Format

Share Document