Faculty Opinions recommendation of Long-term Impact of Crystalloid versus Colloid Solutions on Renal Function and Disability-free Survival after Major Abdominal Surgery.

2018 ◽  
Author(s):  
Michael James
Keyword(s):  
Renal Function ◽  
Abdominal Surgery ◽  
Major Abdominal Surgery ◽  
Free Survival ◽  
Long Term Impact

scholarly journals Long-term Impact of Crystalloid versus Colloid Solutions on Renal Function and Disability-free Survival after Major Abdominal Surgery

2019 ◽  
Vol 130 (2) ◽  
pp. 227-236 ◽  
Author(s):  
Alexandre Joosten ◽  
Amélie Delaporte ◽  
Julien Mortier ◽  
Brigitte Ickx ◽  
Luc Van Obbergh ◽  
...  
Keyword(s):  
Renal Function ◽  
Abdominal Surgery ◽  
Estimated Glomerular Filtration Rate ◽  
Free Survival ◽  
Crystalloid Solution ◽  
Significant Difference ◽  
Goal Directed Fluid Therapy ◽  
Balanced Crystalloid

Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background The authors recently demonstrated that administration of balanced hydroxyethyl starch solution as part of intraoperative goal-directed fluid therapy was associated with better short-term outcomes than administration of a balanced crystalloid solution in patients having major open abdominal surgery. In the present study, a 1-yr follow-up of renal and disability outcomes in these patients was performed. Methods All patients enrolled in the earlier study were followed up 1 yr after surgery for renal function and disability using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS). The main outcome measure was the estimated glomerular filtration rate. Other outcomes were serum creatinine, urea, pruritus, and WHODAS score. Groups were compared on a complete-case analysis basis, and modern imputation methods were then used in mixed-model regressions to assess the stability of the findings taking into account the missing data. Results Of the 160 patients enrolled in the original study, follow-up data were obtained for renal function in 129 and for WHODAS score in 114. There were no statistically significant differences in estimated glomerular filtration rate at 1 yr (ml min−1 1.73 m−2): 80 [65 to 92] for crystalloids versus 74 [64 to 94] for colloids; 95% CI [−10 to 7], P = 0.624. However, the WHODAS score (%) was statistically significantly lower in the colloid than in the crystalloid group (2.7 [0 to 12] vs. 7.6 [1.3 to 18]; P = 0.015), and disability-free survival was higher (79% vs. 60%; 95% CI [2 to 39]; P = 0.024). Conclusions In patients undergoing major open abdominal surgery, there was no evidence of a statistically significant difference in long-term renal function between a balanced hydroxyethyl starch and a balanced crystalloid solution used as part of intraoperative goal-directed fluid therapy, although there was only limited power to rule out a clinically significant difference. However, disability-free survival was significantly higher in the colloid than in the crystalloid group.

scholarly journals SP279POSTOPERATIVE ACUTE KIDNEY INJURY, LONG-TERM RENAL FUNCTION AND MORTALITY IN PATIENTS UNDERGOING MAJOR ABDOMINAL SURGERY: A COHORT ANALYSIS

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii471-iii471
Author(s):  
Natacha Rodrigues ◽  
Joana Gameiro ◽  
Catarina Bekermen ◽  
Joana Neves ◽  
Maria João Melo ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Abdominal Surgery ◽  
Cohort Analysis ◽  
Kidney Injury ◽  
Major Abdominal Surgery

scholarly journals Acute kidney injury, long-term renal function and mortality in patients undergoing major abdominal surgery: a cohort analysis

2016 ◽  
Vol 9 (2) ◽  
pp. 192-200 ◽  
Author(s):  
Joana Gameiro ◽  
Joana Briosa Neves ◽  
Natacha Rodrigues ◽  
Catarina Bekerman ◽  
Maria João Melo ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Abdominal Surgery ◽  
Cohort Analysis ◽  
Kidney Injury ◽  
Major Abdominal Surgery

Long-term outcomes of major abdominal surgery and postoperative delirium after multimodal prehabilitation of older patients

Surgery Today ◽  
2020 ◽  
Vol 50 (11) ◽  
pp. 1461-1470
Author(s):  
Ties L. Janssen ◽  
Ewout W. Steyerberg ◽  
Chantal C. H. A. van Hoof-de Lepper ◽  
Tom C. J. Seerden ◽  
Dominique C. de Lange ◽  
...  
Keyword(s):  
Abdominal Surgery ◽  
Older Patients ◽  
Postoperative Delirium ◽  
Major Abdominal Surgery ◽  
Long Term Outcomes

scholarly journals Long-Term Survival After Complications Following Major Abdominal Surgery

2016 ◽  
Vol 20 (5) ◽  
pp. 1034-1041 ◽  
Author(s):  
Jennifer Straatman ◽  
Miguel A. Cuesta ◽  
Elly S. M. de Lange – de Klerk ◽  
Donald L. van der Peet
Keyword(s):  
Abdominal Surgery ◽  
Major Abdominal Surgery ◽  
Term Survival ◽  
Long Term Survival

scholarly journals MP52-07 SHORT AND LONG TERM IMPACT OF TOBACCO SMOKING ON DONOR RENAL FUNCTION FOLLOWING LIVE KIDNEY DONATION

2020 ◽  
Vol 203 ◽  
pp. e774
Author(s):  
Christopher Kauffman-Ortega* ◽  
Adrian M. Garza-Gangemi ◽  
Mariano Oropeza-Aguilar ◽  
Bernardo Gabilondo-Pliego ◽  
Francisco T. Rodriguez-Covarrubias
Keyword(s):  
Renal Function ◽  
Tobacco Smoking ◽  
Kidney Donation ◽  
Live Kidney Donation ◽  
Short And Long Term ◽  
Long Term Impact

Long-Term Impact of Bariatric Surgery

2017 ◽  
Author(s):  
Michael E. Hochman
Keyword(s):  
Bariatric Surgery ◽  
Gastric Bypass ◽  
Abdominal Surgery ◽  
Vertical Banded Gastroplasty ◽  
Clinical Case ◽  
Long Term Impact ◽  
Study Intervention ◽  
Landmark Study

This chapter provides a summary of a landmark study in abdominal surgery. Does bariatric surgery in obese individuals reduce mortality? Starting with that question, it describes the basics of the study, including funding, year study began, year study was published, study location, who was studied, who was excluded, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, gives a summary and discusses implications, and concludes with a relevant clinical case involving possible bariatric surgery, including gastric banding, vertical banded gastroplasty, or gastric bypass, for an obese man who has not had success with dieting.

scholarly journals Effectiveness and Nephrotoxicity of Long-Term Tacrolimus Administration in Patients with Ulcerative Colitis

2020 ◽  
Vol 9 (6) ◽  
pp. 1771
Author(s):  
Keiichi Haga ◽  
Tomoyoshi Shibuya ◽  
Kei Nomura ◽  
Koki Okahara ◽  
Osamu Nomura ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Renal Function ◽  
Medical Records ◽  
Careful Monitoring ◽  
Relapse Free Survival ◽  
Free Survival ◽  
Effective Option ◽  
Term Administration ◽  
Potential Use

Background: Tacrolimus (TAC) is used for the management of ulcerative colitis (UC). However, there are few reports on the effectiveness of its long-term administration. TAC is also known to cause renal toxicity. The aim of this study was to evaluate long-term effectiveness and monitor changes in renal function during prolonged TAC use in patients with UC. Methods: Medical records of 50 UC patients treated with TAC were retrospectively reviewed. Clinical outcomes were assessed at 6, 12, 24, and 36 months after initiating TAC. We also monitored chronological changes in renal function. Results: Thirty-nine patients were treated with TAC for more than 3 months. Relapse-free survival among these patients at 6, 12, 24, and 36 months was 82%, 69%, 41%, and 23%, respectively. On the other hand, renal function was reduced in 35.9% of patients. We found that irreversible renal dysfunction was more likely to occur in cases in which the estimated glomerular-filtration rate (eGFR) was reduced by more than 30%. Conclusion: This study demonstrated the potential use of TAC as an effective option in the long-term medical management of UC, although it tended to increase the risk of nephrotoxicity. There is a need for the careful monitoring of renal function during TAC administration.

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