scholarly journals Ocimum gratissimum Lineu: Uma revisão de seus efeitos farmacológicos e usos medicinais / Ocimum gratissimum Lineu: A review of its pharmacological effects and medicinal uses

2021 ◽  
Vol 4 (6) ◽  
pp. 28716-28732
Author(s):  
João Pedro Costa Dos Santos ◽  
Hugo de Castro Martins Rodrigues ◽  
Henry Evangelista Resende ◽  
Bernardo Brandão Barbosa ◽  
Luiz Paulo de Abreu Rosa ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Michael Buenor Adinortey ◽  
Justice Kwabena Sarfo ◽  
Jeffery Kwarteng ◽  
Cynthia Ayefoumi Adinortey ◽  
William Ekloh ◽  
...  

Launaea taraxacifolia (Willd.) Amin ex C. Jeffrey is a herb found mostly in tropical Africa. The plant, commonly found in West Africa, is used in the management of many diseases including cardiovascular, respiratory, haematological, endocrine, and metabolic diseases in Ghana, Nigeria, Benin, Serra Leone, and Senegal. This piece provides comprehensive and updated information on the traditional uses, phytochemical constituents, and pharmacological and toxicological information available on Launaea taraxacifolia to support its medicinal uses and also unearth knowledge gaps for future studies. An electronic literature search using search engines, namely, Google Scholar, ScienceDirect, and PubMed, was carried out to obtain information on the plant. Both common and scientific names of the plant were used as keywords for the search process. This paper captured information on Launaea taraxacifolia from 1985 to 2018. The search revealed that the leaves of the plant possess nutritional/pharmacological effects on diseases such as diabetes mellitus, hypertension, cancer, malaria, bacterial infections, and arthritis. The leaf has been shown to be a rich source of phytoconstituents such as flavonoids, phenolic acids, tannins, alkaloids, glycosides, coumarins, triterpenoids, ascorbic acid, lycopene, and β-carotene. Also, isolated phytoconstituents as well as the safety profile of the plant have been documented. This review on Launaea taraxacifolia has provided a one-stop documentation of information in support of the several purported ethnopharmacological uses of the plant. It also reveals information gaps such as the need to research into its pharmacokinetics, interactions with drugs of importance, and its development into a plant-based drug in order to expand its clinical use.


2016 ◽  
Vol 4 (2) ◽  
pp. 161-165 ◽  
Author(s):  
Priscilla Alexander

The leaves of Ocimum gratissimum having some ethno-medicinal applications were investigated. The phytochemicals screening of the leaves using Standard Methods and further analysis with HPLC revealed the presence of tannins, saponins, flavonoids, alkaloids, phlobatanins, terpenoids, steroids and cardiac glycosides. The elemental analysis was carried out using Atomic Absorption Spectrophotometer (AAS). The result revealed the presence of Na (0.311±0.049), Ca (0.138 ±0.111), Mg (1.712 ± 0.537), K (0.261± 0.077), Mn (0.457±0.107, Pb (0.005 ± 0.002), Zn (0.200 ±0.06), Cu (0.803±0.818), N (0.286± 0.052), and Fe (0.312 ± 0.067).  Cd and Cr were not detected in the samples. This investigation suggested that Ocimum gratissimum leaves are rich in phytochemical constituents which contributed to its medicinal uses. The leaves of Ocimum gratissimum can be said to contain some components of medical value since the chemical components elaborated by it are active principles (alkaloid, steroids and glycosides). Ocimum gratissimum also contain most of the essentials elements indicating its nutritive values and less toxic as Cd and Cr were not detected in the leaf.Int J Appl Sci Biotechnol, Vol 4(2): 161-165


2021 ◽  
Vol 11 (2) ◽  
pp. 237-240
Author(s):  
Neha Choudhary ◽  
Narinder Singh ◽  
Ajeet Pal Singh ◽  
Amar Pal Singh

Maslinic Acid a characteristic compound of the triterpenoid bunch got from olive which forestalls the age of favorable to fiery cytokines and oxidative pressure, found in an assortment of common sources, going from home grown cures utilized in traditional medicine to consumable vegetables and organic products present in the Mediterranean eating routine. A few investigations have demonstrated that maslinic acid a wide scope of pharmacological effects such as Antimalarial Effect, Anti-Proliferative Activity, Antitumor Activity, Antifungal Activity, Antibacterial Activity, Anti-diabetic Effect, Antioxidant effect, Anti-inflammatory Activity, Cardio protective effect, Neuroprotection effect, Antiviral Activity, Antimicrobial Activity. Keywords:  Maslinic acid, Triterpene, edible source, Pharmacological Effects


Author(s):  
Preeti Gautam ◽  
Payal Mittal

Neem (Azadirachta indica) is a medicinal plant, mostly found in the Himalayan region. The neem leaf is commonly and historically used in medicine to treat a variety of illnesses such as eye disorders, nose bleeding, loss of appetite and liver problems etc. Because of its various pharmacological and therapeutic effects, it is included in the Ayurvedic pharmacopoeia. As a result, this review provides current information on ethno-medicinal uses, phytochemistry, pharmacological effects, adverse effects of Azadirachta indica with future advancement. Several references were checked for identification, in-depth literature including online databases, documents, and blogs. Around 29% of the compounds in Azadirachta indica have been isolated and characterised. The limonoids in the neem tree have a wide variety of antimicrobial and insecticidal properties. Complex azadirachtin, salanin are active principles extracted from neem seed. These metabolites' biochemical pathways in the neem tree are completely unknown. Citrus sinensis is related to the neem tree phylogenetically. 62 percent of neem genomic was anchored into citrus chromosomes according to comparative study. The azadirachtin, nimbin, salanin and nimbidin from neem tissues were quantified by using LC-MS. This paper shows the various use of neem in different disorder.


Author(s):  
Manish Kapoor ◽  
Gurdeep Kaur ◽  
Navneet Kaur ◽  
Chanchal Sharma ◽  
Kajal Batra ◽  
...  

The genus Hibiscus belongs to the mallow family, Malvaceae comprising of about 275 species growing in tropical and sub tropical areas. The various species of genus Hibiscus have been used as traditional medicine all over the world. There are numerous reports of their traditional medicinal uses in various countries like India, Nigeria, China, and Srilanka etc. to cure various ailments such as hypertension, cardiac diseases, stomach-ache, urine problems, skin diseases and many more. Based on the historical knowledge, various pharmacological and phytochemical studies on some species of the genus Hibiscus have been done. Nevertheless, there are no up-to-date articles published which can provide an overview of pharmacological effects of the genus Hibiscus. Therefore, the main objective of the review article is to provide a systematic comprehensive summary of traditional uses, phytochemistry and pharmacology of the genus Hibiscus and to build up a correlation between its traditional ethano-botanical uses and pharmacological activities so as to find some advanced research opportunities in this field. The given information on the ethano-botanical uses, phytoconstituents and various medicinal properties of the genus Hibiscus was gathered from the online scientific databases through search in Google, Google Scholar, Science Direct, NCBI, Pubmed, Springer Link, Research Gate by using some keywords as. Besides these websites other published literature and unpublished Ph.D. thesis and M.Sc. dissertation were also consulted. Previously conducted research revealed that the genus contains good amount of phytoconstituents such as antioxidants, phytosterols, saponins, lignin, essential oils, glycosides, and anthocyanins etc. Presence of these bioactive compounds in the crude extracts of the plants make it suitable for various medicinal properties like anti inflammatory, anti-diabetic, anti-obesity, anti-proliferative, anti-ulcer, hypersensitive, hypolipidemic, hepatoprotective, nephroprotective and many more. Additionally, this review article showed that mainly two species of the genus i.e. H. rosa-sinensis and H. sabdariffa have been explored for their pharmacological activities. There are few reports on some other species like H. tiliaceous, H. microanthus, H. asper, H. acetosella. This review highlights the medicinal potential of the plant Hibiscus due to its unique blend of phytochemicals. These phytoconstituents can be further assessed and subjected to clinical trials for their proper validations. Although large amount of the data regarding pharmacological effects has already been added to the existing reservoir but still potential of certain species like H. radiatus, H. hirtus, H. moschetous, H. trionum and many more is not yet unveiled and can be considered as future prospects that need to be worked out.  Graphical Abstract: 


2018 ◽  
Vol 64 (01) ◽  
pp. 3-9
Author(s):  
Andzela Brajanovska ◽  
Biljana Bauer

Helleborus sp. are healing plants from the family Ranunculaceae. The aim of this paper is to consider ethnopharmacology and the toxicity of the hellebores which is focused on a detailed research of the value of phytochemicals, as pharmacological attributes of phytomedicine herbs. The data is based on active components. Also, this paper presents the chemical composition of the root in the overall effect of the drug, as well as the importance of the hellebores in pharmacy. It shows a wide range of pharmacological effects such as cardiotonic, immunostimulative, antibacterial, antitumor, diuretic, and emetic. Helleborus odorus Waldst. et Kit. is rich with secondary metabolites such as bufadenolides, flavonoids, phenolic heterozids. With this research it was concluded that these plants have great significance and great application in the formulation of pharmaceutical dosage forms. Keywords: Helleborus sp., phytomedicine, folk medicinal uses, cardiotonic, toxicity, hellebore


2018 ◽  
Vol 19 (2) ◽  
pp. 12
Author(s):  
Adela Astudillo Vázquez ◽  
Hortencia Dávalos Valle ◽  
Alfredo Patiño Siciliano

In Mexico, the use of medicinal plants to treat health disorders has been practiced since pre-Columbian times. Unfortunately, this knowledge has been lost over time, mainly in highly urbanized  areas. We conduct an ethnobotanical survey about Alternanthera repens, Kuntze (Amaranthaceae) and Bidens odorata Cav. (Asteraceae) in Mexico City. A total of 500 peope were interviwed, 250 of them were questioned about B. odorata and 250 in relation  to A. repens, the questions included: common names, medicinal uses, part of the plant used, mode of preparation, route of administration and duration of treatment. This study revealed that both plant species are currently used in top diseases, in the study area, mostly to treat gastrointestinal disorders, specifically diarrhea; A. repens is also recommended to treat fever and renal diseases, whereas B. odorata is used for treating diabetes, renal disorders and less frequently for fever and as forage. The results allow us to ensure that these plants are used today and are potentially important to continue with the determination of their pharmacological effects and other aspects.


2014 ◽  
Vol 28 ◽  
pp. 1-9
Author(s):  
Ganapathy Murugan Alagu Lakshmanan ◽  
Selvarasuvasuki Manikandan

Plectranthus forskohlii (Willd). Briq. (Syn: Coleus forskohlii) is an important indigenous medicinal plant in India. It has been used in traditional Ayurveda medicine for curing various disorders and this is the only source of the diterpenoid forskolin. Forskolin is used for the treatment of eczema, asthma, psoriasis, cardiovascular disorders and hypertension, where decreased intracellular cAMP level is believed to be a major factor in the development of the disease process. A comprehensive account of the morphology, medicinal uses, phytochemistry, pharmacological activities, analytical methods and biotechnological approaches for forskolin production reported are included in view of the many recent findings of importance on this plant.


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