Based on the strong characteristics of comprehensiveness and practicality of the Mechatronics Control Engineering Class, a PBL based “One main line, Two links, Three practical points” teaching mode and methodology has been formed in 7-year exploring and practicing and has been applied in the teaching reform in mechatronics control engineering class at Beihang University. By implementing the method, excellent results have been gained and the teaching task has been accomplished well. It meets the requirement of cultivating innovative talents for the current social development and is worthwhile to be extended widely.