A RARE CASE OF ROSAI-DORFMAN DISEASE IN HYPOTHYROIDISM PATIENT A DIAGNOSTIC COEXISTENCE

2021 ◽  
pp. 31-32
Author(s):  
Gridhati Srinivas ◽  
Tarun Kumar Dutta
Keyword(s):  
Weight Loss ◽  
Differential Diagnosis ◽  
Soft Tissue ◽  
Rare Case ◽  
Cervical Lymphadenopathy ◽  
Nodal Involvement ◽  
Nodal Disease ◽  
Rosai Dorfman Disease ◽  
Night Sweats ◽  
Rule Out

Rosai-Dorfman disease (RDD) is a rare, benign, and predominantly nodal disease that most commonly presents as bilateral, painless cervical lymphadenopathy; although inguinal, axillary, mediastinal, and hilar lymphadenopathy has also been reported. Apart from nodal involvement, RDD has extra nodal manifestations involving bone, soft tissue, and liver as well as constitutional symptoms of fever, night sweats, and weight loss, which make it reasonable to rule out the infectious, autoimmune, and malignant conditions as the differential diagnosis.

scholarly journals Tuberkulosis tonsil dan nasofaring disertai limfadenopati servikal dan tuberkulosis milier

2014 ◽  
Vol 44 (1) ◽  
pp. 69
Author(s):  
Rina Hayati ◽  
Abdul Rachman Saragih
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Head And Neck ◽  
Rare Case ◽  
Clinical Presentation ◽  
Cervical Lymphadenopathy ◽  
Mycobacterial Infection ◽  
Upper Aerodigestive Tract ◽  
Neck Masses ◽  
Soft Tissue Masses

Latar belakang: tuberkulosis pada saluran nafas atas sangat jarang dijumpai dan biasanya disertai dengan penyakit paru primer. Dengan kemajuan pengobatan tuberkulosis saat ini, infeksi mycobacterium pada tonsil dan nasofaring jarang dijumpai. Limfadenopati servikal merupakan simptom yang sering terjadi, dan seharusnya didiagnosis banding dengan suatu massa di kepala dan leher. Tujuan: untuk menambah pengetahuan dalam mendiagnosis dan menangani tuberkulosis tonsil dan nasofaring yang jarang dijumpai. Kasus: Seorang anak laki-laki 14 tahun dikonsulkan dengan masa dileher bilateral disertai disfagia, demam dan malaise selama satu bulan. Penatalaksanaan: Pasien awalnya kami diagnosis banding sebagai suatu massa di kepala leher. Setelah ditegakkan diagnosis sebagai tuberkulosistonsil dan nasofaring disertai limfadenopati servikal dan tuberkulosis milier, diberikan terapi dengan anti tuberkulosis dan diperoleh hasil yang baik. Kesimpulan: Tuberkulosis sebaiknya dimasukkan sebagai diagnosis banding suatu massa di kepala dan leher terutama jika gambaran klinis dan pencitraan yang dijumpai tidak khas, sementara itu biopsi dan gambaran mikrobiologi selalu harus dipertimbangkan. Kata kunci: tuberkulosis nasofaring, tonsil, millier, limfadenopati. ABSTRACTBackground: Tuberculosis (TB) of the upper aerodigestive tract is rare and is usually associated with primary pulmonary disease. With recent advances in medical treatment of tuberculosis, mycobacterial infection of the nasopharynx and tonsil becomes very rare. The most common presenting symptom is cervical lymphadenopathy, so TB should be considered in the differential diagnosis of soft tissue masses of the head and neck. Purpose: To remind Otolaryngologists about the diagnosis and management of nasopharyngeal and tonsillar tuberculosis, which become rare case nowadays. Case: A 14-year-old boy was consulted with bilateral neck masses, disphagia, fever and malaise for one month. Case Management: At first we made a differential diagnosis of soft tissue masses of the head and neck. After he was diagnosed as nasopharyngeal and tonsilar tuberculosis with cervical lymphadenopathy and millier tuberculosis, the patient was treated with anti tuberculosis medication and the result was  good. Conclusion: TB should be considered in the differential diagnosis of soft tissue masses of the head and neck, particularly when the imaging findings and clinical presentation are atypical, at which point appropriate biopsies and microbiologic studies should be conducted. Keyword : Nasopharyngeal tuberculosis, tonsilar tuberculosis, cervical lymphadenopathy, milliertuberculosis

scholarly journals A Solitary Ventral Scapular Osteochondroma causing Pseudo-winging of Scapula: A Case Report

2021 ◽  
Vol 11 (7) ◽  
Author(s):  
Eknath Pawar ◽  
Nihar Modi ◽  
Amit Kumar Yadav ◽  
Jayesh Mhatre ◽  
Sachin Khemkar ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Soft Tissue ◽  
Young Child ◽  
Chest Wall ◽  
Rare Case ◽  
Rare Presentation ◽  
Medial Border ◽  
Soft Tissue Masses ◽  
Scapular Region

Introduction: Winging of scapula is defined as a failure of dynamic stabilizing structures that anchor the scapula to the chest wall, leading to prominence of the medial border of scapula. It could be primary, secondary, or voluntary. Primary winging could be true winging due to neuromuscular causes or pseudo-winging due to osseous or soft-tissue masses. A scapular osteochondroma is a very rare presentation site and causes pseudo-winging leading to pushing away of the scapula away from the chest wall presenting as medial border prominence. Here, we are reporting a rare case of a scapular osteochondroma causing a pseudo-winging of the scapula. Case Report: A 2-year-old male child presented with painless, immobile, and non-fluctuant swelling over the left scapular region, insidious in onset and progressive in nature. On examination, a non-tender, immobile swelling was palpable with a painless and unrestricted range of motion at the shoulder joint. After evaluating radiographs and CT scan, the patient was diagnosed to have a ventral scapular osteochondroma leading to pseudo-winging of the scapula. Conclusion: Despite the rarity, a differential diagnosis of a scapular osteochondroma should be kept in mind while examining a young child presenting with a winged scapula. Keywords: Scapula, osteochondroma, pseudo-winging.

scholarly journals Cutaneous Polyarteritis Nodosa Presenting Atypically with Severe Pharyngeal Ulceration

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Bayanne Olabi ◽  
Justin C. Mason ◽  
Ziad Farah
Keyword(s):  
Weight Loss ◽  
Differential Diagnosis ◽  
Magnetic Resonance Angiography ◽  
Polyarteritis Nodosa ◽  
Rare Case ◽  
Significant Weight Loss ◽  
Histological Assessment ◽  
Cutaneous Polyarteritis Nodosa ◽  
Nodular Lesions ◽  
Appropriate Therapy

Polyarteritis nodosa (PAN) is a multisystem, necrotising vasculitis of small- and medium-sized arteries with a predilection for the visceral vessels. Cutaneous PAN is a rare variant with symptomatic vasculitis limited to the skin, typically presenting as nodular lesions on the extremities with a propensity to ulcerate. We describe a rare case of histologically confirmed cutaneous PAN presenting in a 55-year-old Ghanaian woman with severe oropharyngeal ulceration. This was associated with dysphagia and significant weight loss. Oesophagoduodenoscopy showed that the ulceration extended throughout the oropharynx. Systemic polyarteritis nodosa was ruled out with magnetic resonance angiography. Our patient was treated successfully with corticosteroids and methotrexate. This case suggests that cutaneous PAN should be considered in the differential diagnosis of patients with oropharyngeal ulceration and that histological assessment is pivotal in establishing the diagnosis early in order to instigate appropriate therapy.

scholarly journals Kikuchi-Fujimoto Disease: A Report of 3 Cases

2007 ◽  
Vol 86 (7) ◽  
pp. 412-413 ◽  
Author(s):  
Eimear Phelan ◽  
Emer Lang ◽  
Peter Gormley ◽  
John Lang
Keyword(s):  
Weight Loss ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Accurate Diagnosis ◽  
Histiocytic Necrotizing Lymphadenitis ◽  
Kikuchi’S Disease ◽  
Node Biopsy ◽  
Night Sweats ◽  
Necrotizing Lymphadenitis ◽  
Kikuchi's Disease

Cervical lymphadenopathy has many underlying etiologies. One of its rare causes is Kikuchi-Fujimoto disease (Kikuchi's disease, histiocytic necrotizing lymphadenitis). We discovered such a cause in a 37-year-old woman who had presented with malaise, night sweats, and weight loss in addition to cervical lymphadenopathy. We based our diagnosis on excisional lymph node biopsy. We also review 2 other cases of Kikuchi's disease that were diagnosed by others at our institution. Clinically and histologically, Kikuchi's disease is very similar to lymphoma, and distinguishing the two is difficult. However, despite the fact that Kikuchi's disease is benign, an accurate diagnosis is important because misdiagnosis might lead to unnecessary surgery and/or chemotherapy.

scholarly journals Rosai Dorfman Disease

2021 ◽  
Author(s):  
Kalpana Giri ◽  
Ashok Baral ◽  
Niva Tiwari ◽  
Krishna Sharma
Keyword(s):  
Rare Case ◽  
Cervical Lymphadenopathy ◽  
Unknown Origin ◽  
Sinus Histiocytosis ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
History Of

Rosai-Dorfman disease (RDD) is referred to as Sinus Histiocytosis Massive Lymphadenopathy (SHML) of unknown origin. We are reporting a rare case of Rosai Dorfman disease, a case of 6 years old male with a history of multiple painless bilateral submandibular and cervical lymphadenopathy.

scholarly journals Rare case of extra-peritoneal brown fat (hibernoma) mimicking dumbbell-shaped liposarcoma

2021 ◽  
pp. 20200162
Author(s):  
Alex Kiu ◽  
Tiffany Fung ◽  
Sungmi Jung ◽  
Rehana Jaffer ◽  
Marie-Helen Martin
Keyword(s):  
Differential Diagnosis ◽  
Adipose Tissue ◽  
Soft Tissue ◽  
Rare Case ◽  
Clinical Presentation ◽  
Soft Tissue Tumour ◽  
Radiological Features ◽  
Tissue Tumour ◽  
Brown Adipose ◽  
Patient Stress

Hibernomas are a very rare and benign soft tissue tumour that originate from brown adipose tissue. While they are not histologically malignant, they may be indistinguishable from aggressive tumours such as liposarcomas on imaging. It is, therefore, important to consider it as a differential diagnosis when a suspicious fatty lesion is seen on imaging. This may prevent unnecessary invasive surgery and patient stress. This paper illustrates the clinical presentation, radiological features, and histological diagnosis of a patient with a rare dumbbell-shaped hibernoma in the pelvis.

Cutaneous Rosai–Dorfman disease: a challenging diagnosis

2021 ◽  
Vol 14 (2) ◽  
pp. e239244
Author(s):  
Rita Sampaio ◽  
Leandro Silva ◽  
Goreti Catorze ◽  
Isabel Viana
Keyword(s):  
Weight Loss ◽  
Differential Diagnosis ◽  
Physical Examination ◽  
Plasma Cells ◽  
Oral Prednisolone ◽  
Inflammatory Cells ◽  
Rosai Dorfman Disease ◽  
History Of ◽  
Nodular Lesions ◽  
Proliferative Disease

Rosai–Dorfman disease is a rare benign histiocytic proliferative disease of unknown cause that, in exceptional cases, presents with lesions confined to the skin. Clinically variable types of lesions such as papules, nodules and plaques have been reported. We present a case of a 27-year-old woman with a 1-year history of erythematous papular and nodular lesions on the malar and right axillary regions, previously misdiagnosed as acne. She reported no fever, malaise or weight loss, while physical examination and laboratory workup were normal. Bacteriological and mycobacteriological cultures were negative. Histopathological findings showed dense infiltration of inflammatory cells involving the entire dermis, consisting of large macrophages with emperipolesis, S100 and CD68 positive, neutrophils, eosinophils, lymphocytes and plasma cells. The patient was treated with oral prednisolone without improvement. Dapsone was subsequently initiated with favourable clinical response. The present article aimed to emphasise the clinical and histological differential diagnosis and share the treatment experience.

scholarly journals Isolated Intracranial Rosai-Dorfman Disease

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Md. Taufiq ◽  
Abul Khair ◽  
Ferdousy Begum ◽  
Shabnam Akhter ◽  
Md. Shamim Farooq ◽  
...  
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Clinical Improvement ◽  
Cervical Lymphadenopathy ◽  
Rare Condition ◽  
Unknown Etiology ◽  
Nodal Involvement ◽  
Rosai Dorfman Disease ◽  
Parasellar Region ◽  
Significant Clinical Improvement

Background. Rosai-Dorfman disease (RDD) is a benign histiocytic proliferative disorder of unknown etiology. This rare condition commonly causes massive cervical lymphadenopathy. Intracranial RDD without any nodal involvement is extremely rare.Case Report. A young Bangladeshi male complained of bilateral complete blindness with left sided deafness for about three years. There was no lymphadenopathy. MRI and CT scan of brain suggested an inflammatory/neoplastic (?meningioma) lesion located at left parasellar region which extended frontally to encircle both optic nerves and also to left prepontine area. Histopathologically the lesion was diagnosed as RDD. The patient was treated with steroid and significant clinical improvement observed.Conclusion. The prognosis of intracranial RDD is not poor. It can be treated with surgery with or without corticosteroids, chemotherapy, and so forth. But as the condition is extremely rare and often misdiagnosed, the clinician, radiologist, and histopathologist should have a suspicion in their mind about the possibility of RDD.

scholarly journals Rosai Dorfman Disease —A rare case of cervical lymphadenopathy

2020 ◽  
Vol 8 (12) ◽  
pp. 2712-2715
Author(s):  
Insiyah Amiji ◽  
Ummulkheir Mohammed ◽  
Hajaj Salum ◽  
Emilia Karugaba ◽  
Luka Mkeni ◽  
...  
Keyword(s):  
Rare Case ◽  
Cervical Lymphadenopathy ◽  
Rosai Dorfman Disease

scholarly journals Kikuchi–Fujimoto Disease in an Old Italian Woman: Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
A. D’Introno ◽  
A. Perrone ◽  
A. Schilardi ◽  
A. Gentile ◽  
C. Sabbà ◽  
...  
Keyword(s):  
Weight Loss ◽  
Differential Diagnosis ◽  
Case Report ◽  
Excision Biopsy ◽  
Review Of The Literature ◽  
Old Patients ◽  
Italian Woman ◽  
Night Sweats ◽  
Young Subjects ◽  
Asian People

Kikuchi–Fujimoto disease (KFD) is a rare, benign, generally self-limiting disease that has higher prevalence in Asian people with a few cases reported in European countries. It generally affects young subjects under 40 years of age and is characterized by regional lymphadenopathy. Here, we present a case of a 66-year-old Italian woman who was extensively examined for right unilateral laterocervical lymph nodes associated with fever, night sweats, fatigue, and weight loss. She was diagnosed as having the KFD only after an excision biopsy of the largest laterocervical lymph node and was then managed symptomatically with NSAIDs. We also made a review of the literature for better awareness of the disease among physicians especially in those countries, like Italy, where the disease is not prevalent and may be frequently misdiagnosed. In fact, to our best knowledge, only seven Italian cases of KFD have been published in the last 15 years with patients being younger than 40 years. We finally highlight that it is noteworthy to consider KFD as differential diagnosis of lymphadenopathy even in old patients, and, since a misdiagnosis of lymphoma is actually feasible, an early biopsy has to be taken into account for confirming diagnosis and helping in the timely and appropriate management.

Sign in / Sign up

Export Citation Format

Share Document