PERNIOSIS: AN ENIGMATIC DERMATOLOGICAL ENTITY- STUDY OF ITS DEMOGRAPHIC PROFILE AND NAIL CAPILLAROSCOPIC CHANGES

2021 ◽  
pp. 16-18
Author(s):  
Shivali Aggarwal ◽  
Seema Goel ◽  
Dimple Chopra
Keyword(s):  
Tertiary Care ◽  
Microvascular Disease ◽  
Cross Sectional Study ◽  
North India ◽  
Care Hospital ◽  
Cross Sectional ◽  
Finger Nail ◽  
Long Term Follow Up ◽  
History Of ◽  
Hands And Feet

BACKGROUND: Perniosis is a localised inammatory disorder affecting the unprotected skin regions of individuals exposed to damp, nonfreezing cold. The exact pathogenesis has not been elucidated, however, it is thought to be a microvascular disease. AIMS: To study the demographic prole of patients presenting with perniosis and examine the nailfold capillaroscopic (NFC) changes. MATERIAL AND METHODS: This was an observational, cross-sectional study conducted at a Tertiary care hospital of North India over a period of three months (November 2020- January 2021). Patients with idiopathic perniosis were included in the study. After detailed history and clinical examination, proximal nailfold (PNF) video capillaroscopy was performed in the affected digits. RESULTS: A total of 47 patients with idiopathic perniosis were recruited in the study consisting of 35 females and 12 males with female to male ratio of 2.9:1. A majority of individuals belonged to age group 21-35 years (38.29%). Lesions were localized to both hands and feet in 23 patients (48.9%), only hands in 19(40.4%) and only toes in rest 5 (10.6%) patients. Ten (21.2%) patients had family history of similar complaints and history of smoking was present in 2 (4%) patients. The mean BMI 2 recorded in 37 patients aged >20 years was 20.72+4.32kg/m . Finger nail videocapillaroscopy performed in 42 patients showed dilated capillaries in 42.8%, tortuosity in 40.4% and microhaemorrhages in 28.5% patients. CONCLUSION: In the present study, presence of nailfold capillaroscopic changes suggested that an organic damage to the microcirculation is present in perniosis. Low BMI is an important association for development of perniosis. LIMITATIONS: Long term follow up is required for patients with chilblains to assess permanency of nailfold capillaroscopic changes.

scholarly journals Hospital Based Prevalence of SARS-CoV-2 and Clinico-Demographic Profile of COVID-19 Patients: A Study from a Tertiary Care Hospital of North India

2021 ◽  
pp. 126-136
Author(s):  
Anjum Farhana ◽  
Shoaib Khan ◽  
Reyaz Khan ◽  
Umara Amin
Keyword(s):  
Severe Disease ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
North India ◽  
Common Symptom ◽  
Care Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
History Of ◽  
One Year

Aims: To find out the prevalence, predominant risk factors and various clinico-demographic variables among patients infected with SARS-CoV-2 during the first year of the pandemic. Study Design: Hospital based, cross sectional study. Place and Duration of Study: Postgraduate department of Microbiology, Government Medical College, Srinagar, and associated hospitals, between March 2020 and March 2021. Methodology: Individuals with acute respiratory infection (ILI and SARI), high risk contacts and asymptomatic close contacts of COVID-19 positive patients, hospitalized patients dated for surgeries, pregnant women near expected date of deliveries, travellers were screened. A confirmed case of Covid-19 was defined as a positive result on real-time RT-PCR assay of nasopharyngeal and or Oropharyngeal swab specimens. A total of 2,17,665 samples were collected and processed over a period of one year. Results: Out of 2,17,665 samples, 61.3% were males and 38.7% were females, overall mean age was 34.3 years. 24,009 (11%) tested positive for SARS-CoV-2 infection, among them 63.5% were males while 36.5% were females, the mean age observed was 35.3 years. Highest positivity was observed in the age group of 30 – 39 years (22%), followed by 20 -29 years (20.4%), 12 (0.1%). Among positive cases, 19.4% had a history of contact with a lab confirmed case of SARS-CoV-2, 4.3% were HCW’s and 2.6% were pregnant females. 929 (3.9%) patients who tested positive had presented with SARI. Fever was the most common symptom (62%), followed by cough (41%) and fatigue was reported by 37% patients. Comorbidities were present in 23.2% patients, of which Hypertension 10.8% was the most common, followed by COPD 4.9% and Diabetes mellitus 4%. Conclusion: As evident from our study, COVID-19 has a high positivity (11%) in our region, with males twice more likely susceptible than females. High percentages (62%) of people were symptomatic at presentation, while severe disease was seen in only 3.9% patients. Early aggressive testing is essential to decrease the morbidity and mortality rates associated with COVID-19.

PREVALENCE OF NAFLD AMONG HEALTHY LIVER DONORS

2021 ◽  
pp. 46-48
Author(s):  
Muzaffer Rashid Shawl ◽  
Fahad ul Islam Mir ◽  
Saad Abdul Rahman ◽  
Anil C Anand ◽  
Manav Wadhawan ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Western World ◽  
Care Hospital ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
History Of ◽  
Healthy Liver ◽  
Liver Donors

NAFLD is hepatic pandemic of the twenty rst century, being leading cause of chronic hepatic disease in western world. We did a cross sectional study to nd out prevalence of NAFLD among prospective healthy liver donors at a tertiary care hospital at New Delhi, India over a period from June 2014 to March 2016. 124 apparently healthy prospective liver donors were selected. Exclusion criteria were set to exclude all those who had signicant history of alcohol intake (dened as greater than 30g/day for men and greater than 20g/day for women over last two years), Hepatitis B or C infection, severe surgical weight loss or emaciation, Obstructive Sleep Apnea, Celiac disease, history of drug intake known to cause hepatic steatosis. Out of 124 prospective liver donors included in this study, 29 (23%) donors were found to have fatty liver on USG abdomen; 38 (31%) donors had fatty liver on unenhanced CTof the abdomen (LAI of ≤ 5 HU); 61 (49%) donors had fatty liver on magnetic resonance.

COVID-19: An Experience from a Tertiary Care Hospital of Nowshera

2020 ◽  
Vol 24 (2) ◽  
pp. 149-155
Author(s):  
Hamzullah Khan ◽  
Mohammad Zahid Khan ◽  
Mian Mohammad Naveed
Keyword(s):  
Tertiary Care ◽  
Relevant Information ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Epidemic Area ◽  
History Of ◽  
Severity Of The Disease ◽  
Age Range

Objective: To determine the frequency of COVID-19 and characteristics of patients presenting to the COVID-19 clinic at Qazi Hussain Ahmed Medical Complex (QHAMC) Nowshera. Methodology: This cross-sectional study was conducted from 21st Feb 2019 to April 8, 2020, in QHAMC Nowshera. Relevant information was collected on a pre-designed Performa prepared following the objectives of the study. Results: Out of 220 patients, 165(75%) were males, and 55(25%) females. 96(43.6%) of the patients were in the age range 18-30 years followed by 52(23.6%) in age range 31-45years and 17(7.7%) with age>60 years etc. Out of total the nasopharyngeal swabs of 26(11.6%) strong suspects were sent for PCR testing. 208(94.5%) were sent home while 12(5.5%) were advised quarantine. Forty-seven (21.4%) had a travel history to an epidemic area in the last 14 days. 51(23.2%) had a positive history of contact. Eighty-five (38.6%) had a fever and sore throat followed by 27(12.3%) with (fever & cough), 24(10.9%) with (cough and shortness of breath/dyspnea) and 14(6.4%) with a simple flue, etc. Out of 26 cases, 6(2.7%) were COVID-19 Positive, 12(5.5%) were negative and results of 8(3.6%) were still awaited. The PCR repeated the test for confirmed cases showed;  4(1.8%) negative, one died and one was refractory positive.  A positive correlation (p=0.03, r=0.4) of an increase in age with the severity of the disease/outcome was recorded. Conclusion: The frequency of infectivity with COVID-19 was 2.6%. A higher number of patients with mild symptoms attend the COVID clinic. The rate of infection and mortality was higher in age> 60 years.

scholarly journals Stigma for Mental Disorders among Nursing Staff in a Tertiary Care Hospital

2020 ◽  
Vol 11 (02) ◽  
pp. 237-244
Author(s):  
Sandeep Grover ◽  
Neha Sharma ◽  
Aseem Mehra
Keyword(s):  
Mental Disorders ◽  
Nursing Staff ◽  
Mentally Ill ◽  
Positive Attitude ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
North India ◽  
Care Hospital ◽  
Cross Sectional

Abstract Objective This study aimed to evaluate the prevalence of stigma for mental disorders among nursing staff in a tertiary care hospital, and the secondary objective of the study was to assess the correlation of stigma with the socio-demographic profile and previous experience with mentally ill patients. Methods This cross-sectional study was performed among the 210 nurses working in a tertiary care multispecialty teaching public sector hospital in north India. They were evaluated on community attitudes toward the mentally ill (CAMI) scale. Results About two-thirds of the participants (67.1%) were females and had done graduation (64.2%) in nursing. Nearly 50% of the study participants had an experience of working with mentally ill patients. Female had a more significant positive attitude on the domain of social restrictiveness. Authoritarianism had a significant positive correlation with benevolence and social restrictiveness domains. The benevolence domain had a significant correlation with all other domains. Social restrictiveness domain also had a significant correlation with other domains. Conclusion Nurses have a positive attitude toward mentally ill patients.

scholarly journals The correlation between colposcopy, cervical cytology and histopathology in the diagnosis and management of cervical lesions: a cross sectional study

2020 ◽  
Vol 9 (7) ◽  
pp. 2729
Author(s):  
Pooja Gupta ◽  
Mariyam Faruqi ◽  
Subrat Chandra ◽  
Sameer S. Shah ◽  
Rupita Kulshreshtha
Keyword(s):  
Tertiary Care ◽  
Cross Sectional Study ◽  
Cervical Cytology ◽  
Care Hospital ◽  
Sectional Study ◽  
Cervical Lesions ◽  
Cross Sectional ◽  
Diagnosis And Management ◽  
History Of ◽  
Excellent Tool

Background: The study was undertaken to see the correlation between cervical cytology, histopathology and colposcopy in the diagnosis and management of various cervical lesions.Methods: It is a cross sectional study conducted at a tertiary care hospital in Mumbai, in the department of obstetrics and gynecology from February 2007 to March 2008. A total 55 sexually active women were enrolled for the study who belonged to age group greater than 20 years with history of chronic leucorrhoea or post-coital bleeding/spotting, intermenstrual bleeding/spotting or examination findings of erosion, an unhealthy cervix, a lesion bleeding on touch or an abnormal or suspicious Papanicolaou smear. These women then underwent cytology, colposcopy and cervical biopsy.Results: The accuracy of cytology when compared to colposcopy was 81.82%. The accuracy of colpo-histopathology was 83.6%. The combined accuracy was 76.36%.Conclusions: The simultaneous use of cytological studies and screening colposcopy has been shown to increase the cervical cancer detection. Colposcopy offers an excellent tool in the hands of a gynaecologist to evaluate the uterine cervix and it is not possible to develop this kind of perspective by any other method.

scholarly journals Evaluation of smear microscopy and geneXpert for the rapid diagnosis of pulmonary and extrapulmonary tuberculosis in a tertiary care hospital in North India: a descriptive prospective study

2018 ◽  
Vol 6 (5) ◽  
pp. 1756
Author(s):  
Danish Zahoor ◽  
Anjum Farhana ◽  
Farhath Kanth ◽  
Munazah Bha
Keyword(s):  
Extrapulmonary Tuberculosis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Rapid Diagnosis ◽  
North India ◽  
Smear Microscopy ◽  
High Morbidity ◽  
Care Hospital ◽  
Cross Sectional ◽  
Xpert Assay

Background: Tuberculosis is a global health problem associated with high morbidity and mortality. Rapid diagnosis of tuberculosis is essential for early disease management. Conventional methods like microscopy and culture are associated with low sensitivity and longer time to positivity respectively. The GeneXpert is an integrated device for the rapid detection of Mycobacterium tuberculosis and its sensitivity to rifampicin. We evaluated the performance of gene expert MTB/ RIF assay for the diagnosis of pulmonary and extrapulmonary tuberculosis.Methods: A prospective cross sectional study was carried out in the Department of Microbiology. Samples were subjected to smear microscopy by ZN staining, culture on solid (LJ) and liquid media (BacT Alert) and GeneXpert assay.Results: 122 pulmonary samples and 153 extrapulmonary samples collected from 275 patients were included in the study. Out of these, 48 samples were positive by both culture and Xpert assay and 2 samples were culture positive only. Out of 225 culture negative samples, 3 were positive by GeneXpert. The sensitivity for GeneXpert was much higher compared to smear micrscopy (96 Vs 46% respectively). The Xpert assay also detected 3 rifampcin resistant cases.Conclusions: The test appeared to be as sensitive as culture for the detection of tuberculosis in smear positive, smear negative and extrapulmonary tuberculosis. We recommend the use of GeneXpert assay for the early detection of tuberculosis. We conclude that the test is simple and routine staff can perform the test with minimal training.

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