Detergent properties as the basis of the dimexide therapeutic effect in AA-amyloidosis infectious nature (clinical case analysis)

2020 ◽  
Vol 24 (2) ◽  
pp. 60-71
Author(s):  
V. Rameev ◽  
L. Kozlovskaya ◽  
A. Rameeva ◽  
P. Tao
Keyword(s):  
Therapeutic Effect ◽  
Medical Practice ◽  
Clinical Case ◽  
Clinical Observation ◽  
Case Analysis ◽  
Systemic Amyloidosis ◽  
Aa Amyloidosis ◽  
Functional Amyloid ◽  
History Of

The article discusses the current possibilities of postinfectious AA-amyloidosis treatment with dimexide on the example of clinical observation, discribes in detail the problem of functional amyloid and debates the prospects of the principle of amyloid resorption in the treatment of systemic amyloidosis. The history of the use of dimexide in medical practice is given, thenecessary dataon the pharmacology of dimexide are presented.

A clinical case of systemic amyloidosis in a cardiologists’s practice

The Clinician ◽  
2019 ◽  
Vol 13 (1-2) ◽  
pp. 72-79
Author(s):  
V. G. Okorokov ◽  
O. V. Evsina ◽  
V. A. Fomina ◽  
G. O. Ivanova ◽  
E. S. Soldatov ◽  
...  
Keyword(s):  
Clinical Case ◽  
Clinical Observation ◽  
Restrictive Cardiomyopathy ◽  
Systemic Amyloidosis ◽  
Immunohistochemical Method ◽  
Shortness Of Breath ◽  
Normochromic Anemia ◽  
High Level ◽  
Histological Verification

The aim of the work was to study the clinical case of systemic amyloidosis.Materials and methods. Patient Ch., 63 уears old, have admitted to the regional cardiological dispensary with complaints of short stabbing pains in the heart, without reaction to nitroglycerin, interruptions in the work of the heart, mainly at night, shortness of breath with little exertion, weakness, swelling of the legs and feet in September 2018. Sick from April 2016, when was dyspnea on exertion. The high level of creatinine, normochromic anemia have detected. In June 2016 chronic pyelonephritis was diagnosed. In August 2018, a right-sided hydrothorax was diagnosed, a pleural puncture was performed.Results. Laboratory and instrumental research methods were performed. Based on anamnesis data (normochromic anemia, proteinuria, increased creatinine in the blood), clinical picture, data of instrumental studies (restrictive cardiomyopathy, bilateral hydrothorax) clinical diagnosis was made: systemic amyloidosis the kidneys and heart with chronic kidney disease C5 and chronic heart failure. Histological evidence of amyloid and determination of the variant of amyloidosis by immunohistochemical method was recommended. But the patient died before the study. The histological verification of the diagnosis was carried out at the autopsy.Conclusion. This clinical observation is an example of late diagnosis of systemic amyloidosis and postmortal verification of the diagnosis, which is associated with the nonspecific symptoms and the rapidly progressing course of the disease. This case is interesting because amyloidosis proceeded under the guise of other diseases, quickly led to the development of severe heart and renal failure and to the death of the patient before verifying the disease.

scholarly journals Score twice before you cut once: a clinical case of reconstructive bariatric surgery after obesity surgery in a patient with postoperative hypothyroidism and hypoparathyroidism

2021 ◽  
Vol 12 (3) ◽  
pp. 92-97
Author(s):  
N. I. Volkova ◽  
Yu. S. Degtyareva ◽  
M. A. Burikov
Keyword(s):  
Type 2 Diabetes ◽  
Bariatric Surgery ◽  
Vitamin D ◽  
Small Intestine ◽  
Clinical Case ◽  
Clinical Observation ◽  
Reverse Inclusion ◽  
Postoperative Hypoparathyroidism ◽  
History Of

Hundreds of thousands of bariatric surgeries are performed worldwide every year. Th ey have long been proven to be safe and eff ective in treating obesity and type 2 diabetes. Along with an unconditional positive eff ect, these interventions, especially shunting ones, are characterized by specifi c complications. In the absence of proper correction, they can become fatal for patients. One of these complications is malabsorption leading to a defi ciency of vitamins and microelements, which in most cases, is amenable to timely correction in the postoperative period. However, there are situations when it is not possible to carry out an eff ective correction and it becomes necessary to perform reconstructive interventions with the reverse inclusion of the small intestine in the digestion, which is associated with great diffi culties. Th e authors demonstrated this situation in the description of clinical observation of a patient with postoperative hypothyroidism and history of postoperative hypoparathyroidism, who underwent bariatric surgery. Impaired absorption of drugs (L-thyroxine, calcium, and vitamin D), and therefore, uncompensated hypothyroidism and hypocalcemia was an indication for reconstructive surgery.

scholarly journals Complicated aneurysmal bone cyst of the paranasal sinuses in a 9-year-old child

2021 ◽  
pp. 152-158
Author(s):  
E. S. Yadchenko ◽  
I. D. Shlyaga ◽  
D. D. Radzko ◽  
A. V. Novik
Keyword(s):  
Medical History ◽  
Paranasal Sinuses ◽  
Aneurysmal Bone Cyst ◽  
Clinical Case ◽  
Clinical Observation ◽  
Bone Cyst ◽  
Morphological Studies ◽  
History Of ◽  
Immunohistochemical Methods ◽  
One Year

Objective. To analyze a rare clinical case of the aneurysmal bone cyst (ABC) of the paranasal sinuses in a 9-year-old patient.Materials and methods. We studied the data of the anamnesis, diagnostic and treatment methods contained in the medical history of the inpatient. We examined the patient and kept her under clinical observation during the process of the examination and treatment.Results. The fnal diagnosis of the ABC of the paranasal sinuses in the 9-year-old patient was verifed after the obtainment of the results of the performed clinical and morphological studies. The neoplasm was surgically removed. One year after the surgery, the MRI investigation showed no relapse. The child is in a fair condition.Conclusion. To diagnose an ABC, it is required to perform a histological examination of the tumor including the use of immunohistochemical methods.

scholarly journals Case of dental restoration by materials not permitted for use in medical practice

2021 ◽  
Vol 7 (1) ◽  
pp. 48-50
Author(s):  
Evgeny A Nikolaychuk ◽  
Andrei K. Iordanishvili ◽  
Evgeny Kh. Barinov
Keyword(s):  
Medical Practice ◽  
Dental Care ◽  
Clinical Case ◽  
Clinical Observation ◽  
Dental Treatment ◽  
Dental Restoration ◽  
Filling Material ◽  
Bodily Harm ◽  
Periodontal Inflammation ◽  
The Right

Introduction: In recent years, endodontic dental treatment associated with periodontal inflammation in the provision of emergency and planned dental care is not provided with the appropriate standard and quality. Clinical case: Clinical observation is done to a patient suffering from exacerbation of chronic periodontitis, who underwent restoration of 2.6 teeth with light-cured filling material 15 years ago, and intraroot pins of which are made of materials that are not approved for medical practice use. Conclusion: The use of inappropriate material in medical practice for tooth restoration gives the patient the right to seek for material and moral compensation for bodily harm.

scholarly journals Therapeutic and diagnostic algorithm for colon lipoma

2021 ◽  
Vol 1 (5) ◽  
pp. 101-103
Author(s):  
I. Yu. Korzheva ◽  
N. E. Chernekhovskaya ◽  
E. V. Galaeva ◽  
N. V. Vychuzhanina ◽  
E. A. Khoreva
Keyword(s):  
Intestinal Obstruction ◽  
Clinical Features ◽  
Case History ◽  
Clinical Relevance ◽  
Clinical Case ◽  
Clinical Observation ◽  
Diagnostic Algorithm ◽  
Morphological Examination ◽  
History Of ◽  
Colonic Lipoma

Clinical relevance: Colon lipomas are not rare tumors, but they occur with blurred clinical features and patients arrive with complications- obstructive intestinal obstruction or bleeding. In this regard, the authors presented a clinical case of a 57-yearold patient whose diagnosis was established only by morphological examination of the surgical material.The purpose of the study was to demonstrate clinical observation of colon lipoma.Materials and methods: The case history of a 57-year-old patient diagnosed with colonic lipoma is presented.

scholarly journals A case of lepromatous leprosy

2020 ◽  
Vol 27 (2) ◽  
pp. 144-151
Author(s):  
E. Yu. Yanchevskaya ◽  
V. V. Duiko ◽  
O. A. Mesnyankina ◽  
Yu. Yu. Levicheva
Keyword(s):  
Clinical Case ◽  
Clinical Observation ◽  
Lepromatous Leprosy ◽  
Close Attention ◽  
Timely Diagnosis ◽  
Tourist Flows ◽  
Depth Study ◽  
History Of

This article describes a clinical case of lepromatous leprosy. Despite the sporadic incidence of leprosy in Russia, the presented clinical observation demonstrates that clinicians must maintain vigilance with regard to leprosy. Close attention and in-depth study of the history of the disease is required both in endemic and (in view of active migration and tourist flows) non-endemic regions, since timely diagnosis of this mycobacteriosis can present significant difficulties.

Clinical case of periostitis in pregnant women complicated by sepsis

2020 ◽  
pp. 61-63
Author(s):  
S. Sh. Kakvaeva ◽  
M. A. Magomedova ◽  
A. N. Dzhalilova
Keyword(s):  
Pregnant Woman ◽  
Multiple Organ Failure ◽  
Pregnant Women ◽  
Organ Failure ◽  
Clinical Case ◽  
Clinical Observation ◽  
Infectious Agent ◽  
Modern Medicine ◽  
Multiple Organ ◽  
Number Of Patients

One of the most serious problems of modern medicine is sepsis. The number of patients undergoing this complication is 20–30 million (WHO) annually and has no tendency to decrease. Sepsis is characterized by severe multiple organ failure due to a violation of the response of the macroorganism to an infectious agent. Moreover, it is dangerous with high mortality. Sepsis often develops in patients with immunodeficiency conditions, which primarily include pregnant women. The article presents a clinical observation of a case of periostitis in a pregnant woman complicated by a septic state.

Clinical case of amyloid goitre due to idiopathic AA-amyloidosis

2015 ◽  
Author(s):  
Dmitry Pasechnik ◽  
Elena Sinelnik ◽  
Natalya Volkova ◽  
Maria Porksheyan
Keyword(s):  
Clinical Case ◽  
Aa Amyloidosis

THERAPEUTIC MANAGEMENT OF ASCITES IN SPITZ DOG IN BANGLADESH WITH A BRIEF REVIEW ON CANINE ASCITES

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
M. A. Samad
Keyword(s):  
Ascitic Fluid ◽  
Clinical Examination ◽  
Clinical Case ◽  
Abdominal Distension ◽  
Multiple Organ ◽  
Therapeutic Management ◽  
Vitamin Supplement ◽  
Case Record ◽  
Successful Recovery ◽  
History Of

Background: Ascites is one of the most important clinical syndromes, caused by multiple organ disorders, characterized by abdominal distension with accumulation of fluid of various colors and consistencies depending on the etiology that are encountered commonly in canine practice worldwide. Although it has been reported from different countries including India but it has not yet been documented from Bangladesh. Objectives: To evaluate the successful therapeutic management of a clinical case of ascites in dog supported with its brief review for its appropriate application Materials and Methods: A female Spitz dog two and half years old brought for treatment with the history of abdominal distension on 1st November 2009. Clinical examination, abdominocentesis and laboratory examination of ascitic fluid were used for the diagnosis of ascites in dog. Results: Clinical examination revealed dyspnea, discomfort, lethargy, weakness, pale mucous membrane, normal rectal temperature 103.2 0F and distended abdomen with fluid thrill on palpation. Examination of ascitic fluid revealed clear white fluid (pure transudate) which is mainly hepatic origin resulting portal hypertension and hypoproteinaemia. Treatment with restricted sodium diet, antibiotic (amoxicillin), diuretic (furosemide; Lasix, Sanofi Aventis) and vitamin B-complex and C- vitamin supplement with regular monitoring assisted in successful recovery. The recovered dog survived for next five years up to 2014 and then died due to other reasons. Conclusions: This clinical case record on canine ascites with successful treatment along with review especially on the methods of diagnosis and cause-wise treatment would certainly help the clinician for proper management of the clinical cases of canine ascites. Keywords: Ascites, Spitz dog, Diagnosis, SAAG, Therapeutic management, Brief review

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