IMPROVEMENT OF INFORMATIVITY OF COMBINED DIFFERENT-RANGE IMAGES IN MEDICAL DIAGNOSTICS

Author(s):  
А.Н. Ветров ◽  
А.Ю. Потлов

Задача повышения качества результатов медицинской диагностики и удобства их интерпретации является актуальной на современном этапе развития биомедицинской инженерии. Особый интерес представляют методы визуализации, применимые при диагностике онкологических заболеваний. Повышать достоверность медицинской диагностики таких патологических состояний предлагается посредством совмещения разнодиапазонных изображений, в частности сканов в инфракрасном и видимом диапазонах длин волн. Предлагается методика, в которой два изображения конкретного биообъекта, полученные от датчиков, работающих в разных частотных диапазонах, имеющие одинаковые пространственные параметры и сформированные с общего ракурса, сводятся в общее изображение чересстрочно. Новизна предлагаемой методики заключается в том, что после совмещения изображений производится взаимная передача заданных частей каждого пикселя соседним пикселям по вертикали. В полученном изображении каждый пиксель содержит информацию оптического и инфракрасного изображений в заданных пропорциях. Показано, что предлагаемая методика обеспечивает увеличение информативности в полученном изображении в шесть раз относительно исходных изображений. Предлагаемая методика совмещения разнодиапазонных изображений может быть применена в различных прикладных областях In the medical diagnostics of diseases, it is necessary to obtain the most reliable information in order to obtain the correct diagnosis and, as a result, the correct treatment for the patient. One of the methods of diagnostic studies of oncological diseases of a near-surface nature is to obtain infrared images. It is possible to increase the reliability of information by combining images obtained from thermal imagers, as well as from television video cameras. In this paper, we propose a technique in which two images of a particular object obtained from sensors operating in different frequency ranges, having the same spatial parameters, and formed from the same angle, are interlaced into a common image. The novelty of the proposed method lies in the fact that after combining the images, the specified parts of each pixel are mutually transmitted to the neighboring pixels vertically. In the resulting image, each pixel contains information of optical and infrared images in appropriate proportions. It is shown that the proposed method provides an increase in information content in the resulting image six times relative to the original image. The proposed technique for combining multi-range images can be applied in various areas

2020 ◽  
Vol 15 ◽  
Author(s):  
Ying X Gue ◽  
Rahim Kanji ◽  
Sabiha Gati ◽  
Diana A Gorog

MI with non-obstructive coronary artery (MINOCA) is a condition previously thought to be benign that has recently been shown to have comparable mortality to that of acute coronary syndrome with obstructive coronary disease. The heterogeneity of the underlying aetiology makes the assessment, investigation and treatment of patients with MINOCA challenging. The majority of patients with MINOCA presenting with ST-segment elevation MI generally have an underlying coronary or myocardial cause, predominantly plaque disruption or myocarditis. In order to make the correct diagnosis, in addition to the cause of the presentation, a meticulous and methodical approach is required, with targeted investigations. Stratification of patients to guide investigations that are more likely to provide the diagnosis will allow the correct treatment to be initiated promptly. In this article, the authors review the contemporary incidence, aetiology, recommended assessment and treatment of patients with MINOCA presenting with ST-segment elevation MI.


2020 ◽  
Vol 25 (4) ◽  
pp. 47-49
Author(s):  
Tamas Toth ◽  
Ana-Maria Prişcă ◽  
Angela Borda ◽  
Horea Gozar ◽  
Radu-Alexandru Prişcă

Abstract The most common causes of non-bilious vomiting in infants are hypertrophic pyloric stenosis and pylorospasm. Differential diagnosis between the pathologies establishes the correct treatment. The aim of our study is to present the management of the pathologies cured in our department. The longer the duration of vomiting symptoms the higher muscle thickness was shown. Dehydration and lethargy was associated with higher muscle thickness. There were no intraoperative or postoperative complications recorded in our cases. Ultrasonography is the gold standard in imaging technique but it requires an experienced radiologist. In case of negative physical examination and ultrasonography, but high suspicion of the diagnosis a fluoroscopy may be required. The correct diagnosis avoids unnecessary surgery combined with general anesthesia.


Author(s):  
Yuriy Zack

The main problems in making a correct diagnosis are: subjectivity and insufficient qualifications of the doctor, difficulties in correctly assessing the patient’s complaints, signs and symptoms of the disease observed in the patient, as well as individual manifestations of the symptoms of the disease. In publications on the use of expert systems for medical diagnostics using fuzzy logic, the main attention was paid to the medical features of the problem. In this work, for the first time, general methodological aspects of building such systems, creating databases, representing by fuzzy sets of real numbers, digital scales, linguistic and Boolean data of symptom values are formulated. The types of membership functions that are advisable to use to represent the symptoms of diseases are proposed. In fuzzy-logical conclusions, not only the values of the characteristic functions of the logical terms of individual symptoms, but also complex arithmetic functions of their values are used.


2020 ◽  
Vol 24 (01) ◽  
pp. e31-e37
Author(s):  
Donata Gellrich ◽  
Moritz Bichler ◽  
Christoph A. Reichel ◽  
Florian Schrötzlmair ◽  
Pamela Zengel

Abstract Introduction Diseases of the salivary glands are rare in children and adolescents, with the exception of viral-induced infections. Objective To determine the clinical course of the disease, the diagnostic procedures, the treatment and the outcome of all children and adolescents affected with salivary gland diseases at our clinic over a period of 15 years. Methods A retrospective chart review including a long-term follow-up was conducted among 146 children and adolescents treated for salivary gland disorders from 2002 to 2016. Results Diagnosing acute sialadenitis was easily managed by all doctors regardless of their specialty. The diagnosis of sialolithiasis was rapidly made only by otorhinolaryngologists, whereas diagnosing juvenile recurrent parotitis imposed difficulties to doctors of all specialties – resulting in a significant delay between the first occurrence of symptoms and the correct diagnosis. The severity-adjusted treatment yielded improvements in all cases, and a full recovery of 75% of the cases of sialolithiasis, 73% of the cases of juvenile recurrent parotitis, and 100% of the cases of acute sialadenitis. Conclusions Due to their low prevalence and the lack of pathognomonic symptoms, salivary gland diseases in children and adolescents are often misdiagnosed, resulting in an unnecessarily long period of suffering despite a favorable outcome following the correct treatment.


Author(s):  
Prakhar Maheshwari ◽  
Rajesh Kumar Maheshwari ◽  
Anuradha Kusum ◽  
Digvijay Agarwal

Plasma cell rich osteomyelitis is a rare finding characterised by a plethora of plasma cells localised in the affected bone without the typical clinical features of infection. It usually affects the metaphysis of long bones with a radiological appearance as a dense thickening of bone without sequestrum formation. We present an atypical case of plasma cell osteomyelitis with a lesion in the metaphysis as well as the diaphysis of the humerus without sclerosis but with sequestrum formation. An 11-year-old girl was brought to OutPatient Department (OPD) with complaints of post-traumatic pain and swelling at left shoulder and proximal arm since one and a half months with aggravation of symptoms since last 10 days. Patient had also been treated for Urinary Tract Infection (UTI) by a paediatrician who prescribed antibiotics and antipyretics because of which fever subsided but the pain persisted. The x-ray of left shoulder with arm revealed a fracture of surgical neck of humerus with cortical irregularity noted in the mid-shaft of humerus along with lamellated periosteal reaction suggestive of post-traumatic osteomyelitis with a pathological fracture. Clinicoradiologic diagnosis of pathological fracture of left neck of humerus was made with an underlying neoplastic or infective aetiology. An open biopsy was taken from left proximal humerus. Histopathological examination showed plasma cells in sheets having abundant basophilic cytoplasm, round to eccentric nuclei and perinuclear hoff along with lymphocytes and few polymorphs with surrounding area showing fibrosis, oedema and hyperemia. A diagnosis of chronic plasma cell osteomyelitis was rendered, which is an uncommon condition without specific clinical findings and an ambigious cause. Histopathology is the definitive tool for obtaining an accurate diagnosis and we strongly recommend a meticulous histopathological examination correlated with clinico-radiological description for a correct diagnosis in order to avoid an increased frequency of diagnosis of neoplastic plasma cell lesion as well as for advocating the correct treatment. This case is discussed for presentation of plasma cell osteomyelitis and also to report a case of chronic primary plasma cell rich osteomyelitis with atypical clinical features.


Author(s):  
I.V. Pronin ◽  
M.I. Shcherbakov

Recently, medical thermography has attracted more and more attention from physicians and physiologists, especially in the study of complex diseases. Thermograms show the distribution of thermal fields, corresponding or not corresponding to normal thermography of specific areas. The presence of a pathological thermal picture indicates a certain pathology. Medical thermography makes it possible to conduct an examination in a short time (5-10 minutes) with the construction of accurate heat maps and is a safe method of primary diagnosis. Infrared thermal mapping provides a study of the development of a thermoactive process in time, which increases the diagnostic capabilities of the method, especially in the early stages of disease development. The aim of this work is to study the possibilities of medical thermography in the treatment of malignant meningioma by the method of alfitherapy. Alphitherapy (algo – algae, phyto– plants) is a direction in medicine, veterinary medicine, cosmetology, which is distinguished by the fact that it allows you to completely restore the entire body and get rid of hormonal, chronic, acute and concomitant diseases due to a proper balanced diet, which consists of algae, plants, macro- and microelements, vitamins with the presence of plant microorganisms. The data obtained as a result of many years of research indicate that alpha drugs contain a rich set of biologically active substances with versatile pharmacological activity, which are successfully used to treat a wide range of cardiovascular and oncological diseases, injuries and other health disorders. The results of application of the method of medical thermography in alfitherapy based on the portable thermograph IRTIS-2000 ME are presented. A patient was considered whose results of thermographic examination revealed malignant meningioma (brain cancer). As a result of the use of the alfitherapy method, the malignant meningioma was completely cured without surgery. A description of the biological mechanisms of alfitherapy and alfitherapeutic action for the treatment of cardiovascular and oncological diseases is given. The areas of application of medical thermography in medical diagnostics are presented. It has been shown that the use of medical thermography allows non-invasive primary diagnostics and monitoring of the state of human health, and alfitherapy allows effective non-surgical restoration of the whole organism, regardless of nosology.


Author(s):  
Petr Arkadiyevich Ilyin

As with any other clinical discipline, otorhinolaryngology uses both simple investigation methods including external examination of ENT organs with an otoscope, rhinoscope and laryngoscope, and more complex ones requiring the use of special devices and equipment. The latter include X-ray examination, US diagnostics, endomicroscopy of the nose and paranasal sinuses, CT and MRI (in case the study of soft tissue formations is needed). To study the auditory analyser functions and the labyrinth state, a number of functional tests are performed including stabilometry or postulography. Audiometry is performed with electroacoustic instruments and can be subjective and objective. Impedancometry, a method of objective hearing assessment, based on measuring the acoustic resistance of a soundconducting device, is used to determine the location and nature of the auditory system disorders. All these methods help establish the correct diagnosis, clarify the localisation of the pathological process and prescribe the correct treatment.


2021 ◽  
Vol 15 (3) ◽  
pp. 224-229
Author(s):  
Cristhian Rene Vargas Estrada ◽  
Bruna Fernanda Firmo ◽  
Marjury Cristina Maronezi ◽  
André de Mattos Faro ◽  
Daniele Belchior Vela ◽  
...  

Mammary neoplasms in female dogs present a high incidence. Several histological types are observed, among them, micropapillary carcinoma is considered one of the most aggressive because it is related to vascular invasion, metastases and low survival time. Aimed to describe a case of micropapillary breast carcinoma, with cutaneous metastasis, in a dog. A canine, female, 14 years old, 8kg, not defined breed, uncastrated, nulliparous, with pseudocyesis and no contraceptives administration history was attended at the Veterinary Reproduction and Obstetrics Service from "Governador Laudo Natel” Hospital, FCAV, UNESP, Jaboticabal, presenting a breast ulcerated nodule, with one month estimated evolution. After stabilization and preoperative exams, radical unilateral mastectomy and ipsilateral axillary and inguinal lymphadenectomy were performed. Histopathologic diagnosis revealed micropapillary carcinoma and free surgical margins from neoplasm, however, there were metastasis in both lymph nodes. The tutors did not adhere to antineoplastic chemotherapy. In 60th post-surgical day, there was inflammatory reaction in the surgical scar region, with small cutaneous ulceration, where the elastogram  revealed  rigidity and shear velocity of 7.84m/s. Skin biopsy revealed metastasis of micropapillary breast carcinoma. There was progression of ulcerations, compromising animal’s welfare and its physiological activities, when on the 110th post-surgical day, it was decided to euthanize the patient.  The correct diagnosis and knowledge of tumor biological behavior are importants points to choose the correct treatment. The adjuvant chemotherapy treatment can impact on average survival time and ARFI elastography is an accurate predictor of rapid and non-invasive diagnosis of micropapillary carcinoma recurrence.


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