Understanding the Relationship between Microbiome, Diet and Cancer Risk

When it comes to the microbiome, people usually think of the gut, but there is also the breast microbiome, and its role in the health and risk of breast cancer is not fully understood. A microbiome is a collection of microorganisms that live in a specific environment in the body. Diet can affect the breast microbiome, which shows that like the gut microbiome, breast microbiomes can respond to diet. New research now shows that diet, including fish oil supplements, can alter not only the breast microbiome but also its cancerous tumors. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management

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Differential Diagnosis of Benign and Malignant Breast Masses Using Diffusion-Weighted Magnetic Resonance Imaging (MRI)

10.36811/jca.2021.110022 ◽

2021 ◽

pp. 514-552

Author(s):

Elena Locci ◽

Silvia Raymond

Keyword(s):

Breast Cancer ◽

Magnetic Resonance Imaging ◽

The Body ◽

Resonance Imaging ◽

Breast Masses ◽

Malignant Breast ◽

Weighted Magnetic Resonance Imaging ◽

Keywords Cancer ◽

Magnetic Resonance Imaging Mri ◽

New Research

When it comes to the microbiome, people usually think of the gut, but there is also the breast microbiome, and its role in the health and risk of breast cancer is not fully understood. A microbiome is a collection of microorganisms that live in a specific environment in the body. Diet can affect the breast microbiome, which shows that like the gut microbiome, breast microbiomes can respond to diet. New research now shows that diet, including fish oil supplements, can alter not only the breast microbiome but also its cancerous tumors. Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management

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The relationship between the fear of breast cancer, risk factors, and early diagnosis behaviors of women by age groups

Perspectives In Psychiatric Care ◽

10.1111/ppc.12720 ◽

2021 ◽

Author(s):

Seçil Taylan ◽

İlknur Özkan ◽

Selma Öncel

Keyword(s):

Breast Cancer ◽

Risk Factors ◽

Breast Cancer Risk ◽

Cancer Risk ◽

Early Diagnosis ◽

Age Groups ◽

Cancer Risk Factors ◽

Breast Cancer Risk Factors ◽

The Relationship

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Abstract PS7-02: The relationship of established breast cancer risk factors with breast cancer subtypes

10.1158/1538-7445.sabcs20-ps7-02 ◽

2021 ◽

Author(s):

Anne Marie McCarthy ◽

Tara Friebel ◽

Wei He ◽

Michaela Welch ◽

Sarah Ehsan ◽

...

Keyword(s):

Breast Cancer ◽

Risk Factors ◽

Breast Cancer Risk ◽

Cancer Risk ◽

Breast Cancer Subtypes ◽

Cancer Risk Factors ◽

Cancer Subtypes ◽

Breast Cancer Risk Factors ◽

Relationship Of ◽

The Relationship

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CUTANEOUS METASTASES UNVEILING BREST CANCER – THERAPEUTIC AND DIAGNOSTIC CONSIDERATIONS

Journal of Surgical Sciences ◽

10.33695/jss.v7i1.300 ◽

2020 ◽

Vol 7 (1) ◽

pp. 164-168

Author(s):

Florica Sandru ◽

Mihai Cristian Dumitrascu ◽

Aida Petca ◽

Raluca Gabriela Miulescu ◽

Tiberiu Tebeica ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Systemic Disease ◽

Lymph Node Biopsy ◽

The Body ◽

Cervical Region ◽

Cutaneous Lesions ◽

Dermatology Department ◽

Efficient Treatment ◽

Surgery Department

Metastatic cutaneous lesions are seen more commonly in breast cancer than in any other malignancy in women. Secondary breast cancer happens when cancer cells spread from the breast to other parts of the body. Sometimes breast cancer cells can spread to the skin. This can happen through the blood or lymphatic system. The presence of skin metastases signifies widespread systemic disease and a poor prognosis. The chest wall, the abdomen, the back, and the upper extremities are common sites.We present the case of a 69-year-old woman presented to our Surgery Department in June 2019, after appearing in the Dermatology Department a week ago, for the appearance of multiple subcutaneous painless, hardened, skin-colored nodules spread to the cervical region, anterior chest walls and upper limbs. Anatomopathological examination of the skin biopsy, performed on the anterior face of the left arm, showed dermal fragment with neoplastic, suggestive for lobular breast carcinoma (stage IV). The patient was referred to the oncological surgery department where our patient underwent a left total mastectomy and sentinel lymph node biopsy. The technique of mastectomy was the Madden technique. The surgery has no healing character, being more a necessity intervention that seeks to avoid the complications of the local evolution of the disease, such as ulceration, hemorrhage or suppuration, the possibility of applying the other forms of treatment (radiotherapy and / or polychemotherapy), elimination of a source of permanent metastatic sowing thus leading to more efficient treatment.

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From the Table to the Tumor: The Role of Mediterranean and Western Dietary Patterns in Shifting Microbial-Mediated Signaling to Impact Breast Cancer Risk

Nutrients ◽

10.3390/nu11112565 ◽

2019 ◽

Vol 11 (11) ◽

pp. 2565 ◽

Cited By ~ 8

Author(s):

Tiffany M. Newman ◽

Mara Z. Vitolins ◽

Katherine L. Cook

Keyword(s):

Breast Cancer ◽

Breast Cancer Risk ◽

Cancer Risk ◽

Mediterranean Diet ◽

Dietary Patterns ◽

Gut Microbiome ◽

Western Diet ◽

Diet Pattern ◽

The Mediterranean ◽

The Impact

Diet is a modifiable component of lifestyle that could influence breast cancer development. The Mediterranean dietary pattern is considered one of the healthiest of all dietary patterns. Adherence to the Mediterranean diet protects against diabetes, cardiovascular disease, and cancer. Reported consumption of a Mediterranean diet pattern was associated with lower breast cancer risk for women with all subtypes of breast cancer, and a Western diet pattern was associated with greater risk. In this review, we contrast the available epidemiological breast cancer data, comparing the impact of consuming a Mediterranean diet to the Western diet. Furthermore, we will review the preclinical data highlighting the anticancer molecular mechanism of Mediterranean diet consumption in both cancer prevention and therapeutic outcomes. Diet composition is a major constituent shaping the gut microbiome. Distinct patterns of gut microbiota composition are associated with the habitual consumption of animal fats, high-fiber diets, and vegetable-based diets. We will review the impact of Mediterranean diet on the gut microbiome and inflammation. Outside of the gut, we recently demonstrated that Mediterranean diet consumption led to distinct microbiota shifts in the mammary gland tissue, suggesting possible anticancer effects by diet on breast-specific microbiome. Taken together, these data support the anti-breast-cancer impact of Mediterranean diet consumption.

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Organophosphate Pesticide Exposure and Breast Cancer Risk: A Rapid Review of Human, Animal, and Cell-Based Studies

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17145030 ◽

2020 ◽

Vol 17 (14) ◽

pp. 5030 ◽

Cited By ~ 2

Author(s):

Kailynn June Yang ◽

Jennifer Lee ◽

Hannah Lui Park

Keyword(s):

Breast Cancer ◽

Breast Cancer Risk ◽

Cancer Risk ◽

Human Studies ◽

Rapid Review ◽

Cumulative Exposure ◽

Laboratory Studies ◽

Estrogenic Potential ◽

The Relationship ◽

The U.S

Background: Organophosphate pesticides (OPs) are one of the most commonly used classes of insecticides in the U.S., and metabolites of OPs have been detected in the urine of >75% of the U.S. population. While studies have shown that OP exposure is associated with risk of neurological diseases and some cancers, the relationship between OP exposure and breast cancer risk is not well understood. Methods: The aim of this rapid review was to systematically evaluate published literature on the relationship between OP exposure and breast cancer risk, including both epidemiologic and laboratory studies. Twenty-seven full-text articles were reviewed by searching on Pubmed, EMBASE, and Cochrane databases. Results: Some human studies showed that malathion, terbufos, and chlorpyrifos were positively associated with human breast cancer risk, and some laboratory studies demonstrated that malathion and chlorpyrifos have estrogenic potential and other cancer-promoting properties. However, the human studies were limited in number, mostly included agricultural settings in several geographical areas in the U.S., and did not address cumulative exposure. Conclusions: Given the mixed results found in both human and laboratory studies, more research is needed to further examine the relationship between OP exposure and breast cancer risk, especially in humans in non-agricultural settings.

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