scholarly journals Efficacy of 4% chlorhexidine in preventing neonatal umbilical cord infection

2020 ◽  
Vol 14 (03) ◽  
pp. 136-139
Author(s):  
Fouzia Ishaq ◽  
Anila Jamil ◽  
Muhammad Sajjad ◽  
Maria Iftikhar ◽  
Muhammad Adnan Zafar ◽  
...  

Background: Umbilical cord stump is a budding point for bacterial colonization subsequently leading to sepsis that contributes to high neonatal morbidity and mortality, if not properly managed. Antiseptic care can significantly reduce omphalitis and ultimately improve newborn survival. Objective of this study was to see the efficacy of 4% chlorhexidine use to prevent umbilical cord infection in neonates.Subjects and methods: It was a comparative analytical study conducted in Neonatal unit, Sir Ganga Ram Hospital (SGRH) Lahore from July, 2016 till January, 2017. One hundred neonates were enrolled and randomized into two equal group by simple random method (50 each). In one group, nothing was applied to cord while in chlorhexidine group, 4% chlorhexidine gel was applied on umbilicus and around it, once daily for 7 days or till cord detached whichever came early. First application was done by a nurse followed by duly trained mother/caregiver. The signs of omphalitis (redness, pus or localized oedema) were observed and recorded for each neonate in both groups. Chi square test was used to see the difference in omphalitis in these groups with p˂ 0.05 considered as statistically significant result.Results: Out of 100 neonates, 29 (58%) and 23 (46%) males while 21 (42%) and 27 (54%) females neonates belonged to dry care and chlorhexidine group respectively. Nineteen (38%) neonates with dry cord had omphalitis compared to only 5 (10%) in chlorhexidine group (p 0.001). Neonates with chlorhexidine application showed prolonged mean cord separation time (7.9±1.5 days) compared to dry care (6.1±1.8 days). Conclusion: The use of 4% Chlorhexidine was effective to lower omphalitis compared to neonates with dry cord care.

2016 ◽  
Vol 45 (5) ◽  
pp. 198
Author(s):  
Rasyidah Rasyidah ◽  
Yulizar Yulizar ◽  
Lily Emsyah ◽  
Guslihan D Tjipta ◽  
Dachrul Aldy

Objective To compare the effectiveness of 10% povidone iodineto that of 70% alcohol in umbilical cord care of newborn infants.Methods This open label clinical trial was conducted in PirngadiHospital, Medan from July to September 2003. Newborn infantswho fulfilled inclusion criteria were randomly allocated to umbili-cal cord care using 10% povidone iodine or 70% alcohol. Themain outcome measures were omphalitis prevalence, microor-ganism colonization, and time to umbilical cord separation. Cultureof the umbilical cord swab was taken in the first 48-72 hoursafter birth. The umbilical cord was observed daily during hospital-ization and every other day after discharge until cord separation.Statistical analysis was done using chi-square test and indepen-dent t-test.Results There were 54 infants in the povidone iodine group and52 infants in the alcohol group. Omphalitis was absent in bothgroups. Fourteen percent of subjects in the povidone iodine groupshowed no microorganism growth, compared to 7% in the alco-hol group. Staphylococcus aureus colonization was found in10% of subjects in the povidone iodine group and 23% of sub-jects in the alcohol group. The prevalence of Escherichia colicolonization was 41% and 47% in the povidone iodine and alco-hol groups, respectively. There was no statistically significantdifference between both groups in bacterial colonization (P=0.135).Mean time to umbilical cord separation was 6.44 days in thepovidone iodine group and 6.13 days in the alcohol group(P=0.431).Conclusion These results suggest that 10% povidone iodineand 70% alcohol are equally effective in umbilical cord care ofnewborn infants


2021 ◽  
Author(s):  
Suhong Zhao ◽  
Peipei Chen ◽  
Guangrui Shao ◽  
Baijie Li ◽  
Huikun Zhang ◽  
...  

Abstract Objective: To assess the diagnostic ability of abbreviated protocols of MRI (AP-MRI) compared with unenhanced MRI (UE-MRI) in mammographically occult cancers in patients with dense breast tissue.Materials and Methods: The retrospective analysis consisted of 102 patients without positive findings on mammography who received preoperative MRI full diagnostic protocols (FDP) between January 2015 and December 2018. Two breast radiologists read the UE, AP, and FDP. The interpretation times were recorded. The comparisons of the sensitivity, specificity and area under the curve of each MRI protocol, and the sensitivity of these protocols in each subgroup of different size tumors used the Chi-square test. The paired sample t-test was used for evaluating the difference of reading time of the three protocols.Results: Among 102 women, there were 68 cancers and two benign lesions in 64 patients and 38 patients had benign or negative findings. Both readers found the sensitivity and specificity of AP and UE-MRI were similar (p>0.05), whereas compared with FDP, UE had lower sensitivity (Reader 1/Reader 2: p=0.023, 0.004). For different lesion size groups, one of the readers found that AP and FDP had higher sensitivities than UE-MRI for detecting the lesions ≤10 mm in diameter (p=0.041, p=0.023). Compared with FDP, the average reading time of UE-MRI and AP was remarkably reduced (p < 0.001).Conclusion: AP-MRI had more advantages than UE-MRI to detect mammographically occult cancers, especially for breast tumors ≤10 mm in diameter.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
ghufran adnan ◽  
Osman Faheem ◽  
Maria Khan ◽  
Pirbhat Shams ◽  
Jamshed Ali

Introduction: COVID-19 pandemic has overwhelmed the healthcare system of Pakistan. There has been observation regarding changes in pattern of patient presentation to emergency department (ED) for all diseases particularly cardiovascular. The aim of the study is to investigate these changes in cardiology consultations and compare pre-COVID-19 and COVID-19 era. Hypothesis: There is a significant difference in cardiology consultations during COVID era as compared to non-COVID era. Method: We collected data retrospectively of consecutive patients who visited emergency department (ED) during March-April 2019 (non-COVID era) and March-April 2020 (COVID era). Comparison has been made to quantify the differences in clinical characteristics, locality, admission, type, number, and reason of Cardiology consults generated. Results: We calculated the difference of 1351 patients between COVID and non-COVID era in terms of cardiology consults generated from Emergency department, using Chi-square test. Out of which 880 (59%) are male with mean age of 61(SD=15). Analysis shows pronounced augmentation in number of comorbidities [Hypertension(6%), Chronic kidney disease (6%), Diabetes (5%)] but there was 36% drop in total cardiology consultations and 43% reduction rate in patient’s ED visit from other cities during COVID era. There was 60% decrease in acute coronary syndrome presentation in COVID era, but fortuitously drastic increase (30%) in type II myocardial injury has been noted. Conclusion: There is a remarkable decline observed in patients presenting with cardiac manifestations during COVID era. Lack in timely care could have a pernicious impact on outcomes, global health care organizations should issue directions to adopt telemedicine services in underprivileged areas to provide timely care to cardiac patients.


2020 ◽  
Vol 5 (2) ◽  
pp. 85-88
Author(s):  
Lina Astuty

Research: Pre-eclampsia is a disease with signs of hypertension, edema, and proteinuria arising from pregnancy. This disease generally occurs in the third trimester of pregnancy, but can occur earlier, for example in hydatidiform mole (Wiknjosastro, 2005: 282). Preeclampsia and Eclampsia are one of the main causes of maternal mortality in Indonesia. The incidence of preeclampsia ranges from 5-15% of all pregnancies in the world. Based on the 2003 Indonesian Demographic and Health Survey (IDHS), the incidence of preeclampsia in Indonesia is estimated at 3.4–8.5%. The research method used analytical observational method through a case control approach, which is an analytical study concerning how risk factors are studied using a retrospective approach. In other words, the effect is identified now, then the risk factor is identified as having existed or occurred in the past. Research Results The results of the significance test using the Chi-Square test showed a significant relationship to the occurrence of low birth weight (LBW) in mothers with preeclampsia. This is indicated by the value of p = 0.000 which is smaller than α = 0.05, so Ho is rejected. While the results of the calculation of the Odds Ratio show that preeclampsia is one of the causes of LBW, this is indicated by the OR value of 3.028. Conclusion: There is a relationship between preeclampsia and low birth weight in dr. Soedarso Pontianak in 2018 with a probability value (ρ) = 0.000.


2013 ◽  
Vol 1 (3) ◽  
pp. 120-122
Author(s):  
Althea V. Pinto ◽  
Alex X. Chakiath ◽  
Prudhvi Dasari ◽  
Vilekith Reddy ◽  
Shirley George ◽  
...  

Background: A right-sided umbilical cord twist is associated with the presence of a single umbilical artery, congenital malformations and placenta praevia. Methods: It was an observational study. Data was collected from 137 umbilical cords, all from live births and their patient records. The gestational ages ranged from 28 weeks to 41 weeks. The umbilical cords were categorized into right or left, based on the direction of twist. The independent sample T test and the Chi square test were used to analyze the differences between groups. Results: The prevalence of left twist was 84%. Right twist was significantly associated with a larger Hyrtl’s anastomosis (p=0.029) and gestational diabetes (p=0.027). Conclusion: Two previously unreported associations with right twist of the umbilical cord, gestational diabetes and an increase in the diameter of Hyrtl’s anastomosis, were noted in the present study.


Author(s):  
Aprilia Aprisanti Reyani

Latar Belakang :Kehangatan dada ibu dapat menghangatkan bayi, sehingga apabila bayi diletakan di dada ibunya segera setelah melahirkan atau dilakukan Inisiasi Menyusu Dini, dapat menurunkan resiko hipotermia dan menurunkan kematian bayi baru lahir akibat kedinginan atau hipotermia. Tujuan : Tujuan dari penelitian ini adalah untuk mengetahui perbedaan suhu tubuh bayi baru lahir antara bayi yang berhasil melakukan IMD dan bayi yang tidak berhasil melakukan IMD Metode  :Analitik,desain cross sectional,populasi semua bayi baru lahir, sampel bayi barulahir, teknik Non Random Sampling, pengumpulan data dengan menggunakan Lembar Observasi dengan menggunakan uji Chi-Square dengan nilai signifikan α = 0.05 yaitu bila hasil uji statistik menunjukan p ≤ α maka H0 ditolak. Hasil      :Suhu tubuh bayi baru lahir yang berhasil melakukan IMD sebagianbesardengansuhutubuhtidakhipotermisebanyak 20 bayi (87%) Suhu tubuh bayi baru lahir yang tidak berhasil melakukan IMD sebagianbesardengansuhutubuhhipotermisebanyak 8 bayi (66,7%). Dari hasil uji statistik diperoleh hasil nilai p = 0,005 < α = 0.05 maka H1 diterima, artinya ada Perbedaan suhu tubuh bayi baru lahir yang berhasil melakukan IMD dan yang tidak berhasil melakukan IMD Kesimpulan :Terdapat perbedaan suhu tubuh bayi baru lahir antara bayi yang berhasil melakukan IMD dan bayi yang tidak berhasil melakukan IMD.   Kata kunci : Inisiasi Menyusu Dini, Suhu Tubuh Bayi Baru Lahir                                                                                               THE DIFFERENCE BODY TEMPERATURE BETWEEN BABIES WHO SUCCESSFULLY INITIATE BREASTFEEDING EARLY AND BABIESWHO FAIL TO INITIATE EARLY BREASTFEEDING AT RSIA KIRANA SIDOARJO 2019  Background : The warmth of the mother’s chest can warm the baby, so that when the baby is in the mother’s breast immediately after birth or initiated early breastfeeding can reduce the mortality rate of newborns due to hypotermia.Purpose :the purpose of this study was to determine the difference in body temperature of newborns between infants who successfully initiated early breastfeeding and infants who did not succeed in initiating early breastfeedingMethods : analytical, cross sectional design, population 40 newborns, samples 35 newborns, Non Random Sampling techniques, the data accumulation using observation sheets and using chi-square test, with significant value α = 0.05 is when the statistical test results show p ≤ α then Ho is rejected.Result : The body temperature of the newborn who succeeded in initiating early breastfeeding was 36.78ºC with 23 (65.7%) of infants none having hypothermia, the newborn baby's body temperature that did not succeed in doing this early breastfeeding was 35.78ºC With 8 infants experiencing hypothermia, while 4 babies with normal temperature. From the results of statistical tests obtained results with the value p = 0,000 <α = 0.05 then H1 accepted, meaning there is a difference in body temperature of a newborn who successfully initiated early breastfeeding and who did not succeed in Early Breastfeeding Initiation. Conclusion : There is a difference in the body temperature of a newborn between infants who successfully initiated breastfeeding and infants who are not successful in initiating early breastfeeding....Keywords : Early breastfeedinginitiation, newborns temperature


CytoJournal ◽  
2015 ◽  
Vol 12 ◽  
pp. 23 ◽  
Author(s):  
Nora K. Frisch ◽  
Yasin Ahmed ◽  
Seema Sethi ◽  
Daniel Neill ◽  
Tatyana Kalinicheva ◽  
...  

Background: ThinPrep® (TP) cervical cytology, as a liquid-based method, has many benefits but also a relatively high unsatisfactory rate due to debris/lubricant contamination and the presence of blood. These contaminants clog the TP filter and prevent the deposition of adequate diagnostic cells on the slide. An acetic acid wash (AAW) protocol is often used to lyse red blood cells, before preparing the TP slides. Design: From 23,291 TP cervical cytology specimens over a 4-month period, 2739 underwent AAW protocol due to initial unsatisfactory smear (UNS) with scant cellularity due to blood or being grossly bloody. Randomly selected 2739 cervical cytology specimens which did not undergo AAW from the same time period formed the control (non-AAW) group. Cytopathologic interpretations of AAW and non-AAW groups were compared using the Chi-square test. Results: About 94.2% of the 2739 cases which underwent AAW were subsequently satisfactory for evaluation with interpretations of atypical squamous cells of undetermined significance (ASCUS) 4.9% (135), low-grade squamous intraepithelial lesions (LSIL) 3.7% (102), and high-grade squamous intraepithelial lesions (HSIL) 1% (28). From the 2739 control cases, 96.3% were satisfactory with ASCUS 5.5% (151), LSIL 5.1% (139), and HSIL 0.7% (19). The prevalence of ASCUS interpretations was similar (P = 0.33). Although there were 32% more HSIL interpretations in the AAW group (28 in AAW vs. 19 in non-AAW), the difference was statistically insignificant (P = 0.18). AAW category; however, had significantly fewer LSIL interpretations (P = 0.02). The percentage of UNS cases remained higher in the AAW group with statistical significance (P < 0.01). Conclusions: While AAW had a significantly higher percent of UNS interpretations, the protocol was effective in rescuing 94.2% of specimens which otherwise may have been reported unsatisfactory. This improved patient care by avoiding a repeat test. The prevalence of ASCUS and HSIL interpretations between AAW and non-AAW groups were comparable. Though not statistically significant, HSIL interpretations were relatively higher in the AAW group. LSIL interpretations showed lower prevalence in AAW group.


2011 ◽  
Vol 1 (1) ◽  
pp. 33-44
Author(s):  
Anitha R

Job satisfaction is a general attitude towards one’s job, the difference between the amount of reward workers receive and the amount they believe they should receive. Employee is a back bone of every organization, without employee no work can be done. So employee’s satisfaction is very important.Employees will be more satisfied if they get what they expected, job satisfaction relates to inner feelings of workers. As Udumalpet and Palani Taluk are famous for paper industries, the main aim of this study is to analyze the satisfaction level of paper mill employees. Chi-Square test and percentage analysis have been used in this study to analyze the job satisfaction of paper mill employees in Udumalpet and Palani Taluk. The study shows that only 44% of the employees are satisfied with the working conditions, 31% of them with the welfare facilities, 44% of them with the accident compensation, and 42% of them are satisfied with the rewards provided and 52% of them are satisfied with the grievance handling procedure. The organization may give importance to certain factors such as Canteen, rest room facilities, rewards, recognition and promotion policy so that satisfaction of the employees may be improved further.


Author(s):  
Chitturi Prashanthi ◽  
Prashant B Patil ◽  
Vajendra Joshi ◽  
Kiran Kumar K R ◽  
Shilpa R T

: An emergency can be encountered anytime and anywhere. Minimal knowledge about medical emergency and their etiology, primary protocol for management must be known to avoid potential consequences. Hence, the present study was undertaken to compare the knowledge, and ability to handle the medical emergencies among the dental students. A cross-sectional survey was conducted among 100 randomly selected dental students (post-graduate students and interns) comprising of two groups of students those who had underwent training and those who did not. The data obtained was analyzed using the SPSS for windows version 22.0 released 2013. Independent chi square test was used for comparison of responses and independent student t-test was used for the comparison of mean scores. The significance level was set at p&#60;0.001. : The average mean knowledge and ability score was 68% & 61.4% respectively among the participants. On further comparison of mean knowledge & ability scores between the participants with & without basic life support training, participants with BLS training showed better knowledge than those without training and the difference was statistically significant between the two groups (p&#60;0.001%). The study found deficiencies in the knowledge and ability of untrained graduates to deal with medical emergencies as compared to trained.


2021 ◽  
Vol 8 (4) ◽  
pp. 616
Author(s):  
Safaa A. M. Ahmed ◽  
Mohammed A. O. Ali ◽  
Esraa A. A. Mahgoub ◽  
Mohammed Nimir ◽  
Elfatih M. Malik

Background: This study aimed to assess the admission pattern and outcome of neonates managed in the neonatal intensive care unit (NICU) in a Sudanese hospital.Methods: This hospital-based retrospective study was conducted in the NICU of Saad Abu Elella Teaching Hospital in Khartoum, Sudan. Data was collected from medical records of 207 neonates using an extraction form. Chi-square test and binary logistic regression were used in analysis.Results: Most of the neonates were term, and 43% of them had a birth weight less than 2.5 kg. Moreover, the most common morbidities among them were sepsis, respiratory distress syndrome, neonatal jaundice and asphyxia, and the mortality rate was 15%. Additionally, the birth weight, gestational age, the need for resuscitations, direct breast feeding and being beside mother were found to be significantly associated with the studied outcome.Conclusions: Majority of causes of neonatal morbidity and mortality in our study were preventable diseases. Therefore, interventions to improve services in the NICU are highly needed to improve the outcomes.


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