scholarly journals Vitamin D improves inflammatory bowel disease outcomes: Basic science and clinical review

2014 ◽  
Vol 20 (17) ◽  
pp. 4934 ◽  
Author(s):  
Krista M Reich
2019 ◽  
Vol 10 (4) ◽  
pp. 394-400 ◽  
Author(s):  
Ole Haagen Nielsen ◽  
Thomas Irgens Hansen ◽  
John Mark Gubatan ◽  
Kim Bak Jensen ◽  
Lars Rejnmark

Management of inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease, is generally cumbersome for patients and is a massive health-economic burden. In recent years, the immunomodulating effects of vitamin D have gained a huge interest in its possible pathogenic influence on the pathophysiology of IBD. Vitamin D deficiency is frequent among patients with IBD. Several clinical studies have pointed to a critical role for vitamin D in ameliorating disease outcomes. Although causation versus correlation unfortunately remains an overwhelming issue in the illusive chicken versus egg debate regarding vitamin D and IBD, here we summarise the latest knowledge of the immunological effects of vitamin D in IBD and recommend from available evidence that physicians regularly monitor serum 25(OH)D levels in patients with IBD. Moreover, we propose an algorithm for optimising vitamin D status in patients with IBD in clinical practice. Awaiting well-powered controlled clinical trials, we consider vitamin D supplementation to be an affordable and widely accessible therapeutic strategy to ameliorate IBD clinical outcomes.


2014 ◽  
Vol 146 (5) ◽  
pp. S-448-S-449
Author(s):  
Vanessa Mendez ◽  
Andres Yarur ◽  
Emmanuel Coronel ◽  
Amar R. Deshpande ◽  
David H. Kerman ◽  
...  

2012 ◽  
Vol 4 (1) ◽  
pp. 51-56 ◽  
Author(s):  
Sukhdev Chatu ◽  
Vivek Chhaya ◽  
Rosamund Holmes ◽  
Penny Neild ◽  
Jin-Yong Kang ◽  
...  

2021 ◽  
Vol 32 (6) ◽  
pp. 508-518
Author(s):  
Shanzhen Shi ◽  
◽  
Jiaxing Feng ◽  
Lixiang Zhou ◽  
Yu Li ◽  
...  

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