scholarly journals Synthesis, Characterization, Molecular Docking of Sulphamethoxazole Schiff Base Metal Complexes and Its Antibacterial, Anti-Inflammatory and Anti Depressant Activity

2022 ◽  
Vol 16 (1) ◽  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Metal Complexes ◽  
Base Metal ◽  
Anti Inflammatory ◽  
Schiff Base Metal Complexes

scholarly journals Synthesis, Characterization and Electrochemical Sensor Based Upon Novel Schiff Base Metal Complexes Derived from the Non-Steroidal Anti-inflammatory Drug, Flufenamic Acid for the Determination of Uric acid and their Biological Applications

2020 ◽  
Vol 11 (4) ◽  
pp. 11390-11403
Keyword(s):  
Uric Acid ◽  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Schiff Base Ligand ◽  
Flufenamic Acid ◽  
Spectral Studies ◽  
Anti Inflammatory ◽  
Schiff Base Metal Complexes

The current trend in coordination chemistry is the design and synthesis of new Schiff base transition metal complexes for therapeutic, diagnostic, and catalytic applications. For decades, it has been observed that special attention is being paid to the chemistry of Schiff base metal complexes because of their wide range of applications. Therefore the present paper involves the synthesis of Schiff base ligand by altering the functional group of the drug, Flufenamic acid. From that Schiff base ligand, four complexes, i.e., Co(II), Cu(II), Ni(II), and Zn(II) have been prepared (SB metal complexes). The synthesized SB metal complexes have been characterized using several spectral and analytical techniques. All the metal complexes show non-electrolytic behavior suggested by molar conductance measurements. Spectral studies suggest that all four metal complexes exhibit octahedral geometry. The modified SB-Co complex/GCE showed a greater electro-catalytic activity and lower potential towards the oxidation of uric acid (UA). The response of UA was linear over the concentration ranging from CV is 0.5–1.8 μmol/L, sensitivity for 131.85 μAμM-1cm-2, and detection limit for 0.16 μM (S/N=3). The modified GCE showed very good sensitivity along with good repeatability and reproducibility for the determination of UA. The pure drug, Schiff base ligand, and metal complexes, were also screened for anti-inflammatory and antibacterial activities. The observed results prove that the metal complexes exhibit greater activity than that of the original drug.

Novel Schiff base metal complexes: synthesis, characterization, DNA binding, DNA cleavage and molecular docking studies

2018 ◽  
Vol 15 (6) ◽  
pp. 1377-1389 ◽  
Author(s):  
Mayuri Bheemarasetti ◽  
Kavitha Palakuri ◽  
Shweta Raj ◽  
Prakash Saudagar ◽  
Durgaiah Gandamalla ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Dna Binding ◽  
Metal Complexes ◽  
Base Metal ◽  
Dna Cleavage ◽  
Docking Studies ◽  
Molecular Docking Studies ◽  
Schiff Base Metal Complexes

Schiff Base Metal Complexes Precursor for Metal Oxide Nanomaterial: A Review

2020 ◽  
Vol 16 ◽  
Author(s):  
Meghshyam K. Patil ◽  
Vijay H. Masand ◽  
Atish K. Maldhure
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Metal Oxides ◽  
Base Metal ◽  
Carbonyl Compounds ◽  
Organic Transformations ◽  
Iron Cobalt ◽  
Methods Of Synthesis ◽  
Schiff Base Metal Complexes ◽  
Nickel Manganese

: Schiff bases and their complexes are versatile compounds, which have been synthesized from the condensation of carbonyl compounds with amino compounds and exhibit a broad range of applications in biological, medicinal, catalysis, and industrial purposes. Furthermore, Schiff base-metal complexes have been used as a precursor for the synthesis of different metal oxides, which includes oxides of iron, cobalt, copper, nickel, manganese, vanadium, cadmium, zinc, mercury, etc. and ferrites such as Fe3O4, ZnFe2O4, and ZnCo2O4. These metal oxides have been utilized for several applications, which includes as a catalyst for several organic transformations and for biological activity. This review encompasses different methods of synthesis of metal oxides using Schiff base metal complexes precursor, their characterization, and various applications in detail.

Iron (III) and zinc (II) monodentate Schiff base metal complexes: Synthesis, characterisation and biological activities

2021 ◽  
Vol 1231 ◽  
pp. 129946
Author(s):  
Bushra Naureen ◽  
G.A. Miana ◽  
Khadija Shahid ◽  
Mehmood Asghar ◽  
Samreen Tanveer ◽  
...  
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Biological Activities ◽  
Schiff Base Metal Complexes

Syntheses, Structure Analyses and Thermal Stabilities of Two Schiff Base Metal Complexes

2009 ◽  
Vol 27 (9) ◽  
pp. 1697-1702 ◽  
Author(s):  
Yinli Zhang ◽  
Sanping Chen ◽  
Guang Fan ◽  
Zhijie Zhao ◽  
Shengli Gao
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Thermal Stabilities ◽  
Schiff Base Metal Complexes
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