scholarly journals Analysis of the Zimbabwean People’s Response to COVID-19 Vaccine using the HBM on the Zimbabwean People’s Response towards the Anticipated COVID-19 Vaccine

2021 ◽  
Vol 2 (3) ◽  
pp. 174-177
Author(s):  
Yakhya CISRosemary Chigevenga
Keyword(s):  

The Coronavirus disease which started in Wuhan, China in December 2019 has been and continues to claim lives worldwide. It created uncertainties and confusion even in the medical field with its mutations which created new variants which proved to be more dangerous than the original one in some parts of the world leading it to be more fatal in the second wave.

2011 ◽  
pp. 4-20
Author(s):  
M. Ershov

With signs of normalization seemingly in place in the world economy, a number of problems show the possibility of aggravation in the future. The volume of derivatives in American banks grows significantly, high risk instruments are back in place and their use becomes more active, global imbalances increase. All of the above requires thorough approaches when creating mechanisms which can neutralize external shocks for the Russian economy and make it possible to develop in the new post-crisis environment.


2012 ◽  
pp. 84-89
Author(s):  
Quoc Hung Vo ◽  
Nguyen Phuong Nhi Doan ◽  
Dinh Quynh Phu Nguyen ◽  
Thi Dieu Tram Ho ◽  
Thi Hoai Nguyen

Objectives: Nowadays, bioactive substances isolated from marine organisms which are abundant and varied in Vietnamese sea attracted more and more the attention of scientists in the world and Vietnam as well. We have studied on soft coral Sinularia cruciata – Alcyoniidae, which has never been studied in Vietnam before, to find substances which are useful in medical field, especially in anti-cancer therapy. Materials and method: Specimens of soft coral Sinularia cruciata were collected from Con Co, Quang Tri province in May 2011. Pure compounds were isolated by using Thin Layer Chromatography; Column Chromatography normal phase and inverse phase; Shephadex LH 20. Structures of them were determined by spectral data of Nuclear Magnetic Resonance (NMR), Electrospray Ionization Mass Spectrometry (ESI-MS). Results & Conclusion: Structures of 4 compounds were identified: (1) 5.8-epidioxycholest-6-en-3-ol (2) Cholesterol (3) 1-O-hexadecyl-glycerol (Chimyl alcohol) (4) Glycerol 1-O-octadecyl ether (Batyl alcohol). The substance (1) was demonstrated to have strong anti-cancer effects in previous study. Key words Sinularia cruciata, Alcyoniidae, 5,8-epidioxycholest-6-en-3-ol, soft coral, cancer.


Author(s):  
Adyasa Barik ◽  
Pandiyan Rajesh ◽  
Manthiram Malathi ◽  
Vellaisamy Balasubramanian

: In recent years, over use of antibiotics has been raising its head to a serious problem all around the world as pathogens become drug resistant and create challenges to the medical field. This failure of most potent antibiotics that kill pathogens increases the thirst for research to look further way of killing pathogens. It has been led to the findings of antimicrobial peptide which is the most potent peptide to destroy pathogens. This review gives special emphasis to the usage of marine bacteria and other microorganisms for antimicrobial peptide (AMP) which are eco friendly as well as a developing class of natural and synthetic peptides with a wide spectrum of targets to pathogenic microbes. Consequently, a significant attention has been paid mainly to (i) the structure and types of anti microbial peptides and (ii) mode of action and mechanism of antimicrobial peptide resistance to pathogens. In addition to this, the designing of AMPs has been analysed thoroughly for reducing toxicity and developing better potent AMP. It has been done by the modified unnatural amino acids by amidation to target the control of biofilm and persister cell.


1982 ◽  
Vol 29 (4) ◽  
pp. 283-295 ◽  
Author(s):  
Josianne Bodart

While mutual aid is secular, social work as a profession is not yet a hundred years old, and training in this field only began at the turn of the century. Neither priest nor doctor, but equally devoted and competent, the social worker is half-way between the two. His relay function is mediatized by a salary received not from his client, but from an institution which acknowledges he has a cer tain effectiveness. Social work thus reminds us at one and the same time of the priest's priesthood and the doctor's specializa tion. This neo-cleric treats the soul as well as the body and he has ambiguous relations with spelialized institutions which are in pur suit of the sacred or in pursuit of health. The social worker tries to find reference models both in the religious world and in the medi cal world. Furthermore, an analysis of his discourse reveals that he mobilizes items of counter-legitimacy with respect to both the religious and the medical field. This intentionally marginal belonging to two worlds leads him to constantly have doubts about the objectives to be pursued and the decisions to be taken. It is probably in this perspective that the feeling of uneasiness which persuades the world of social work and which prevents these professionals from getting away from vagueness and uncertainty, should be understood.


2021 ◽  
Author(s):  
Mohd. Suhail

<p><a>It has been a great challenge for scientists to develop an anti-covid drug/vaccine with fewer side effects, since the coronavirus began. Of course, the prescription of chiral drugs (chloroquine or hydroxychloroquine) has been proved wrong because these chiral drugs neither kill the virus nor eliminate it from the body, but block SARS-CoV-2 from binding to human cells. Another hurdle in front of the world, is not only the positive test of the patient recovered from coronavirus but also the second wave of Covid 19. Hence, the word demands such a drug or drug combination which not only prevents the entry of SARS-CoV-2 in the human cell but also eliminates it or its material from the body completely. The presented computational study explains (i) why the prescription of chiral drugs was not satisfactory (ii) what types of modification can make their prescription satisfactory (iii) the mechanism of action of chiral drugs (chloroquine and hydroxychloroquine) to block SARS-CoV-2 from binding to human cells, and (iv) the strength of mefloquine to eliminate SARS-CoV-2. As the main protease (M<b><sup>pro</sup></b>) of microbes is considered as an effective target for drug design and development, the binding affinities of mefloquine with the main proteases (M<sup>pros</sup>) of JC virus and SARS-CoV-2, were calculated, and then compared to know the eliminating strength of mefloquine against SARS-CoV-2. The main protease (M<sup>pro</sup>) of JC virus was taken because mefloquine has already shown a tremendous result of eliminating it from the body. The current study includes the docking results and literature data in support of the prescription of a combination of S-(+)-hydroxychloroquine and (+) mefloquine. Besides, the presented study also confirms that the prescription of only hydroxychloroquine would not be so effective as in combined form with mefloquine.</a></p>


Author(s):  
Amruta Barhate ◽  
Prakash Bhatia

Background: The COVID-19 pandemic has made the world to come to a standstill. What started as on 16th March 2020, as 114 confirmed cases of COVID‑19 in the country has now reached worrisome figures. The latest world scenario as per WHO as on 30th November, 2020 is as under-World data: 62,509,444 cases, deaths: 1,458,782; USA: 13,082,877 cases, deaths: 263,946; India: 9,431,691 cases, deaths 137, 139. It is evident that worldwide India is number two in case load and there’s no reason to prevent India from becoming number one unless appropriate corrective steps are taken.Methods: The present study has looked into various data sources available in public domain. The study covered a period of almost nine months i.e., from March 2020 to November 2020. The study revealed a steady increase in the number of COVID-19 cases from March 2020 with peak of pandemic occurring in the mid of September and then a steady decline of cases from October.Results: The data analysis shows that after peaking of cases in September, the epidemic will decline in a phased manner by the end of March 2021. Even though there is a decline seen from the month of October, spike of COVID-19 cases was seen in November in some of the states of India. Therefore, we can’t deny the possibility of a second wave of pandemic to occur in the month of December 2020 and January 2021.Conclusions: Hence appropriate and strict control measures have to be put in place for effective control of the Pandemic and its resurgence.


2021 ◽  
Vol 5 (1) ◽  
pp. 163-178
Author(s):  
Elyta Elyta ◽  
Syarifah Ema Rahmaniah ◽  
Hendra Ramdani

At the beginning of 2020, the world was shocked by the outbreak of Covid-19, which was known to have originated from Wuhan. The increase in cases of local transmission in China's border region with Russia has sparked new concerns. In writing this paper, the author uses data collection methods with literature studies from journals and electronic books, including data from trusted websites through internet searches in the form of soft files that can support the paper's explanation. From the results of this paper, the reader can see that it is divided into several essential points explaining how China's policy to close the border in Russia to prevent the spread of the Covid-19 Virus in their country, first, how the procedures carried out by China in tightening checks on Russian borders. And Second, knowing how China monitors its citizens by using cell phones.


2021 ◽  
Vol 2089 (1) ◽  
pp. 012026
Author(s):  
P Vaishali ◽  
P L S Kumari

Abstract Pandemic caused due to Corona Virus Disease 2019 (COVID-19) affected each and every person life throughout the world. First wave of COVID-19 followed by second wave made situation more panic. Government declared Lockdown imposed strict prohibition on social gathering, unnecessary outing, travelling, and education. During home quarantine, people shared opinion, expressed views, feelings on social media. Home isolation and quarantine affected mental health of people which may lead to depression. Hence in this research article depression is predicted by implementing Neural Network based model. At first level this model implements text classification of COVID-19 based Tweets. Neural network model accuracy is 86.85%. In next level, using same tweet dataset as input, Ensemble learning based model is constructed. This model uses one of the boosting techniques known as Adaboost. Model is executed by varying Train-test-validation ratio. It is observed that accuracy of the model is improved. The model showed accuracy of 99.33 % successfully in every execution. Obtained results are compared with previous work in same area.


2021 ◽  
Vol 41 (1) ◽  
pp. 27-38
Author(s):  
Victor V. Ermolaev ◽  
Julia Voroncova ◽  
Daria K. Nasonova ◽  
Alena I. Chetverikova

Background. The study of the psychological characteristics of social fears during the first wave of COVID-19 indicated that Russian citizens were massively in a state of fear. The persisting threat of a pandemic throughout the year, the inconsistency of managerial decisions in the absence of a coherent strategy to combat COVID-19, obviously create growing social tension in Russia, which is projected onto the psychological level of the state of modern society. Objective. To identify the dynamics of social fears among Russian citizens during the first and second waves of COVID-19. Hypothesis: there is a tendency for the growth of social fears among Russian citizens during the second wave of COVID-19, while the media continues to form a depressive and depressing “picture of the world”. Design. Psychodiagnostics was carried out remotely using Google forms. Sample size: 497 people. At the first stage (the first wave — March / April, 2020), 253 people were tested. At the second stage (second wave — October / November, 2020), 244 people passed testing, of which 150 took part in the periods of both the first and second waves, and 94 — only during the second wave. At the third stage, statistical analysis was carried out in order to identify the dynamics of social fears. Results. From the moment COVID-19 began to the peak of the second wave, Russian citizens showed negative dynamics, characterized by: 1) an increase in the experience of social fears associated with failure and defeat, as well as rejection and suppression; 2) an increase in the imbalance of trust caused by the growth of trust in the world and others, as trustworthy sources of information about the current danger, against the background of a steadily reduced trust in oneself; 3) a decrease in optimism and faith in the future with an increase in the intensity of emotional stress, as well as a desire to delegate responsibility for the events of one’s own life; 4) a general decrease in efficiency (based on the results of self-report). Conclusion. The information broadcast by the media about COVID-19 has a systemic psychological impact through the demonstration of a pessimistic “picture of the world”, which, creating an aggressive information field literally enveloping the psyche, destroys its self-confidence, social ties and group cohesion, and also fills it social fears, increasing the sense of social deprivation. The intended consequences will send the psychological community to develop a predictive model for overcoming this situation. In our opinion, the main thing in the work with the consequences of the pandemic is psychological assistance, the basis of which should be the methods of correction of the cognitive-affective sphere of the individual — the return of self-confidence and the transformation of the “picture of the world” of the present and future into a positive one. Particular attention should be paid to increasing collective cohesion and setting group goals that outline the future positive “picture of the world” of Russian society


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