The Relationship between Brain-derived Neurotrophic Factor’s Serum Level and Hospital Anxiety and Depression Scale-depression in Patients with Psoriasis Vulgaris

BACKGROUND: Psoriasis vulgaris is a chronic inflammatory skin disorder that can lead to depression. The involvement of the nervous system in psoriasis was proved by the influence of brain-derived neurotrophic factor (BDNF) in regulating corneocyte homeostasis. Low level of BDNF in patients with psoriasis result in transit amplifying subpopulation of basal keratinocytes not performing their function as inhibitors of keratinocyte proliferation, resulting in acceleration of keratinocyte proliferation. In depressed patients, it is known that levels of BDNF in the serum and hippocampus are low. BDNF level imbalance potentially affects the severity of psoriasis and depression. METHODS: This is an analytical cross-sectional study. The measurement of BDNFs serum level was carried out in the Medan Private Laboratory using a human BDNF (R and D®, USA) kit using the ELISA method. We use hospital anxiety and depression scale (HADS-D) questionnaire to assess depression symptoms. RESULTS: The results of the Spearman correlation test for BDNFs serum level and HADS-D showed p < 0.05, it can be concluded that there is a correlation between BDNFs serum level and HADS-D. The strength of the relationship between HADS-D and BDNFs serum level is −0.537 that shows moderate correlation (r = 0.4 −<0.6). Relationship between HADS-D and BDNFs serum level is −0.537 that shows moderate correlation (r = 0.4 −<0.6). CONCLUSION: This study shows a moderate negative relationship between BDNFs serum level and the degree of symptoms of depression, which the lower level of BDNFs serum will increase the degree of depression symptoms.

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Anxiety, depression, resilience and self-esteem in individuals with cardiovascular diseases

Revista Latino-Americana de Enfermagem ◽

10.1590/1518-8345.1405.2836 ◽

2016 ◽

Vol 24 (0) ◽

Cited By ~ 9

Author(s):

Isabela Gonzales Carvalho ◽

Eduarda dos Santos Bertolli ◽

Luciana Paiva ◽

Lidia Aparecida Rossi ◽

Rosana Aparecida Spadoti Dantas ◽

...

Keyword(s):

Cardiovascular Diseases ◽

Depression Scale ◽

Self Esteem ◽

University Hospital ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Hospital Anxiety ◽

Resilience Scale ◽

Anxiety Depression ◽

The Relationship

ABSTRACT Objectives: to analyze the relationship between anxiety and depression symptoms, resilience and self-esteem with sociodemographic and clinical characteristics; correlate resilience and self-esteem with age and duration of the disease; check associations between anxiety and depression with measures of resilience and self-esteem among individuals with cardiovascular diseases. Method: correlational study conducted in a large university hospital in the interior of the state of São Paulo, Brazil. The population was composed of adult inpatients with cardiovascular diseases. A non-probabilistic consecutive sample was composed of 120 patients. Variables of interest were assessed using the Hospital Anxiety and Depression Scale, Resilience Scale, and Rosenberg Self-Esteem Scale. Results: anxiety and depression symptoms were present in 32.5% and 17.5% of the patients, respectively, and were associated with the female sex (p = 0.002; p = 0.022). Manifestations of depression were associated with the presence of comorbidities (p = 0.020). More resilient patients did not present depression symptoms (p < 0.001) and anxious women were more resilient (p = 0.042). The highest scores regarding self-esteem were present in patients with anxiety and depression. Men presented higher resilience and lower self-esteem compared to women. Conclusion: patients with anxiety and depression were less resilient but presented higher self-esteem.

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Evaluation of the relationship between perceived social support, coping strategies, anxiety, and depression symptoms among hospitalized COVID-19 patients

The International Journal of Psychiatry in Medicine ◽

10.1177/0091217420982085 ◽

2020 ◽

pp. 009121742098208

Author(s):

Ali Kandeğer ◽

Memduha Aydın ◽

Kürşat Altınbaş ◽

Alparslan Cansız ◽

Özge Tan ◽

...

Keyword(s):

Social Support ◽

Coping Strategies ◽

Perceived Social Support ◽

Depression Scale ◽

Negative Association ◽

Anxiety And Depression ◽

Control Group ◽

Depression Symptoms ◽

Adaptive Coping ◽

The Relationship

Objective We aimed to evaluate the relationship between perceived social support, coping strategies, anxiety, and depression symptoms among hospitalized COVID-19 patients by comparing them with a matched control group in terms of age, gender, and education level. Method The patient group (n = 84) and the healthy controls (HCs, n = 92) filled in the questionnaire including the socio-demographic form, Hospital Anxiety Depression Scale, Multidimensional Perceived Social Support Scale, and Brief Coping Orientation to Problems Experienced through the online survey link. Results The COVID-19 patients had higher perceived social support and coping strategies scores than the HCs. However, anxiety and depression scores did not differ significantly between the two groups. In logistic regression analysis performed in COVID-19 patients, the presence of chest CT finding (OR = 4.31; 95% CI = 1.04–17.95) was a risk factor for anxiety and the use of adaptive coping strategies (OR = 0.86; 95% CI = 0.73–0.99) had a negative association with anxiety. In addition, the use of adaptive coping strategies (OR = 0.89; 95% CI = 0.79–0.98) and high perceived social support (OR = 0.97; 95% CI = 0.93– 0,99) had a negative association with depression symptoms. Conclusions Longitudinal studies involving the return to normality phase of the COVID-19 pandemic are needed to investigate the effects of factors such as coping strategies and perceived social support that could increase the psychological adjustment and resilience of individuals on anxiety and depression.

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A-121 Functional Outcomes in Bilingual Persons with Traumatic Brain: The Role of Mood

Archives of Clinical Neuropsychology ◽

10.1093/arclin/acab062.139 ◽

2021 ◽

Vol 36 (6) ◽

pp. 1171-1171

Author(s):

Winter Olmos ◽

Daniel W Lopez-Hernandez ◽

Isabel Munoz ◽

Laura Schierholz ◽

Rachel A Rugh-Fraser ◽

...

Keyword(s):

Depressive Symptoms ◽

Functional Outcomes ◽

Depression Scale ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Hospital Anxiety ◽

Anxiety Levels ◽

The Relationship ◽

Pearson Correlations

Abstract Introduction We examined the relationship between depression and anxiety, language, and functional outcomes in persons with traumatic brain injury (TBI). Methods The sample consisted of 48 acute TBI (ATBI: 23 Spanish-English Bilinguals; 25 English monolinguals), 30 chronic TBI (CTBI: 17 Spanish English Bilinguals; 12 English monolinguals), and 47 healthy comparison (HC: 29 Spanish-English Bilinguals; 18 English monolinguals) participants. The Hospital Anxiety and Depression Scale was used to measure depression (HADS-D) and anxiety (HADS-A). The Mayo Portland Adaptability Inventory-4 (MPAI-4) was used to measure functional outcomes (ability, adjustment, participation). Results An ANCOVA, controlling for age, revealed the ATBI group reported lower anxiety levels compared to the CTBI group, p = 0.034 np2 = 0.06. HC participants demonstrated significantly higher functional ability compared to both TBI groups, p < 0.05, np2 = 0.08–0.19. The ATBI group demonstrated worse participation scores compared to the CTBI and HC groups, p = 0.001, np2 = 0.11. Pearson correlations revealed mood was related to functional status in ATBI monolinguals (HADS-A: r = 0.29–0.64; HADS-D, r = 0.49–0.62). Monolingual participants with ATBI demonstrated correlations between depressive symptoms and functional adjustment (r = 0.57, p = 0.005) and ability (r = 0.44, p = 0.034). For monolinguals with CTBI, HADS-A correlated with functional outcomes, r = 0.60–0.66, p < 0.05. For bilinguals with CTBI, functional outcomes correlated with HADS-A, r = 0.53–0.66, p < 0.05, and HADS-D, r = 0.54–0.66, p < 0.05. For HC monolinguals, functional outcomes correlated with HADS-A, r = 0.53–0.70, p < 0.05, and HADS-D, r = 0.50–0.72, p < 0.05. Finally, for HC bilinguals, functional outcomes correlated with HADS-A, r = 0.59–0.68, p < 0.05. Conclusion Our results suggest that a relationship between anxiety and depressive symptoms is related more to functional outcomes in monolingual TBI survivors compared to bilingual TBI survivors.

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Anxiety and depression symptoms in family members of icu patients

Avances en Enfermería ◽

10.15446/av.enferm.v33n1.48670 ◽

2015 ◽

Vol 33 (1) ◽

pp. 47-54 ◽

Cited By ~ 5

Author(s):

Maria Kourti ◽

Efstathia Christofilou ◽

George Kallergis

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Demographic Data ◽

Family Members ◽

Depression Scale ◽

Self Report ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Hospital Anxiety ◽

Icu Patients

Objective: This study investigated symptoms of anxiety and depression in relatives of patients admitted in the Intensive Care Unit and determined whether these symptoms were associated to the seriousness of the patients’ condition.Metodology: A total of 102 patients’ relatives were surveyed during the study. They were given a self-report questionnaire in order to assess demographic data, anxiety and depression symptoms. The symptoms of anxiety and depression were evaluated with the Hospital Anxiety and Depression Scale (hads). Patient’s condition was evaluated with a.p.a.ch.e ii Score.Results: More than 60% of patients’ relatives presented severe symptoms of anxiety and depression. No relation was found between symptoms of anxiety and depression of the relatives of patients and patients’ condition of health. On the contrary, these feelings used to exist regardless of the seriousness of patient’s condition.Conclusions: The assessment of these patients is recommended in order serious problems of anxiety and depression to be prevented.

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The Mediational Effect of Weight Self-Stigma in the Relationship between Blatant and Subtle Discrimination and Depression and Anxiety

The Spanish Journal of Psychology ◽

10.1017/sjp.2017.1 ◽

2017 ◽

Vol 20 ◽

Cited By ~ 9

Author(s):

Alejandro Magallares ◽

Patricia Bolaños-Rios ◽

Inmaculada Ruiz-Prieto ◽

Pilar Benito de Valle ◽

Jose Antonio Irles ◽

...

Keyword(s):

Social Stigma ◽

Depression Scale ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Hospital Anxiety ◽

Obesity Stigma ◽

Subtle Discrimination ◽

Dependent Variables ◽

Similar Weight ◽

The Relationship

AbstractObesity may be considered a social stigma. In addition, people with obesity are frequently aware of stigma directed at others who have a similar weight and come to think stigmatized thoughts about themselves. Our study focused specifically on how blatant and subtle discrimination and weight self-stigma are related to depression and anxiety in people with obesity. The sample comprised 170 participants from the Clinical Nutrition Unit of the “Hospital de Valme” (Seville, Spain). The Weight Self-Stigma Questionnaire, the Multidimensional Perceived Discrimination Scale, and the Hospital Anxiety and Depression Scale were used. It was found that blatant and subtle discrimination and weight self-stigma were positively related to depression (.31, .38, and .45 respectively) and anxiety (.30, .36, and .49 respectively; all ps < .01). The path analysis conducted showed that there was a mediational effect of weight self-stigma between blatant (β = .36) and subtle discrimination (β = .40) and depression (β = .24) and anxiety (β = .49; all ps < .01). According to these results, it can be said that weight self-stigma was a full mediator in the model found because the relationships between the independent and the dependent variables were non-significant. Finally, results are discussed in the frame of the obesity stigma literature, and some clinical implications of the results of the study are suggested.

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The Relationship between Anxiety and Depression with Quality of Life among the Elderly with Dementia Living: The Need of Reminiscene Group Therapy in Resident Institutions

Universiti Malaysia Terengganu Journal of Undergraduate Research ◽

10.46754/umtjur.v1i4.96 ◽

2019 ◽

Vol 1 (4) ◽

pp. 95-104

Author(s):

Khadijah Alavi ◽

Noraini Che’ Sharif ◽

Ponnusamy Subramaniam

Keyword(s):

Quality Of Life ◽

Group Therapy ◽

Negative Relationship ◽

Depression Scale ◽

The Elderly ◽

Anxiety And Depression ◽

Clinical Psychologist ◽

Screening Process ◽

The Relationship

This study aims to identify the relationship between anxiety and depression with quality of life among the elderly with dementia living in institution. This study also propose reminscence group therapy in reducing depression and anxiety among residents in institutions. This cross sectional study was conducted at Rumah Seri Kenangan Cheras. A total of 58 elderly with mild to moderate demensia were selected through a series of screening process by a qualified clinical psychologist. Several instruments has been used including Quality of Life-AD (QoL-AD) Geriatric Depression Scale (GDS), Beck Anxiety Inventory (BAI) to investigate the relationship between anxiety and depression with quality of life among the elderly with dementia. This study shows that there is a negative relationship between the level of anxiety and quality of life among the elderly with dementia. Meanwhile, the relationship between depression and the quality of life of elderly with dementia in RSK Cheras shows that there is a significant relationship. The application of reminiscene group therapy as one of the effective intervention to improve quality of life and reduce anxiety and depression among the elderly with dementia in institution were discussed.

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Caregiver Burden Domains and Their Relationship with Anxiety and Depression in the First Six Months of Cancer Diagnosis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17114101 ◽

2020 ◽

Vol 17 (11) ◽

pp. 4101 ◽

Cited By ~ 2

Author(s):

Francisco García-Torres ◽

Marcin J. Jabłoński ◽

Ángel Gómez Solís ◽

María José Jaén-Moreno ◽

Mario Gálvez-Lara ◽

...

Keyword(s):

Longitudinal Study ◽

Caregiver Burden ◽

Cancer Diagnosis ◽

Depression Scale ◽

Psychological State ◽

Anxiety And Depression ◽

Hospital Anxiety ◽

Predictive Utility ◽

Cancer Caregiving ◽

The Relationship

Cancer caregiving is associated with burden and a poor psychological state. However, there is no previous information about the predictive utility of specific burden domains on anxiety and depression in the first six months after a partner’s cancer diagnosis. In a longitudinal study, 67 caregivers completed the Zarit Burden Interview (ZBI) and Hospital Anxiety and Depression Scale (HADS) at T1 (45–60 days after diagnosis) and T2 (180–200 days after diagnosis). Most of the caregivers were female (65.7%, mean age = 51.63, SD = 13.25), while patients were mostly male (56.7%). The TRIPOD checklist was applied. ZBI scores were moderate and HADS anxiety reached significant values. There were no differences in ZBI and HADS between T1 and T2. The relationship between burden, anxiety, and depression were more consistent at T2, while emotional burden at T1 were related and predicted anxiety and depression at T2. Some burden domains were related and predicted anxiety in caregivers in the first six months after partner cancer diagnosis. This information could be useful to prevent the onset of these symptoms in the first six months after diagnosis.

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Active And Avoidant Coping Profiles In Children And Their Relationship With Anxiety And Depression During The COVID-19 Pandemic: A Longitudinal Study

10.21203/rs.3.rs-1145469/v1 ◽

2021 ◽

Author(s):

Qiaochu Zhang ◽

Samuel M.Y. Ho ◽

Yanlin Zhou

Keyword(s):

Longitudinal Study ◽

Internalizing Symptoms ◽

Coping Styles ◽

Child Anxiety ◽

Mainland China ◽

Depression Scale ◽

Avoidant Coping ◽

Anxiety And Depression ◽

Depression Symptoms ◽

The Relationship

Abstract Active and avoidant coping styles are important dispositional factors for the development of anxiety and depression symptoms. Children use both active and avoidant coping together in daily life. No studies have investigated the relationship between active-avoidant coping profiles and internalizing symptoms of children in the COVID-19 pandemic. The present study aimed to investigate children’s active-avoidant coping profiles and assess the relationship of active-avoidant coping profiles to anxiety and depression symptoms in the COVID-19 pandemic. A two-wave longitudinal study was conducted among 322 Chinese children in mainland China during the COVID-19 pandemic. Participants completed the Children’s Coping Strategies Checklist – Revised1 in Time 1 and the Revised Child Anxiety and Depression Scale in Time 1 and 6 months later (Time 2). Four active-avoidant coping profiles were revealed: Low Active copers, High Active copers, Balanced copers, and Avoidant copers. Low and High Active copers were related to lower levels of anxiety and depression symptoms than Balanced copers and Avoidant copers. Avoidant copers showed less decrease in depression symptoms than Balanced copers and High Active copers. It is important to improve children's active-avoidant coping profiles for relieving anxiety and depression symptoms during the COVID-19 pandemic.

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Association Between Levels of Depression Symptoms and Moderately Increased Levels of the Inflammation Marker Albuminuria Is Explained by Age and Comorbidity.

10.21203/rs.3.rs-1054344/v1 ◽

2021 ◽

Author(s):

Solfrid Romundstad ◽

Torfinn Hynnekleiv

Keyword(s):

Depression Scale ◽

Cross Sectional Study ◽

Health Study ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Sectional Study ◽

Inflammation Marker ◽

Hospital Anxiety ◽

Cross Sectional ◽

Symptoms Of Depression

Abstract Background: The study aimed to examine whether there are associations between levels of depression symptoms and levels of the inflammation marker albuminuria. Materials and methods: The 8303 participants in this cross-sectional study were subjects from the second survey of the Trøndelag Health Study (HUNT, Norway). Depression symptoms were assessed by the Hospital Anxiety and Depression Scale (HADS). Logistic regression analysis was performed to estimate the odds ratio (OR) for moderately increased albuminuria (ACR > 3.0 mg/mmol) according to different HADS subgroups and -scores.Results: Unadjusted ORs for moderately increased albuminuria were significantly increased in those with HADS > 8 (OR 1.27, 95% CI 1.05-1.54, p=0.013) and HADS > 11 (OR 1.59, 95% CI 1.19-2.14, p=0.002). However, after adjusting for age and sex, only HADS > 11 was significantly associated with ACR > 3.0 mg/mmol (OR 1.46, 95% CI 1.08-1.98, p=0.014), and after multivariable adjustments for cardiovascular risk factors and comorbidity, there were no significant associations. Conclusion: The positive and significant association between moderately increased albuminuria and symptoms of depression found in unadjusted analyses weakened and disappeared after adjustments. Although individuals with depressive symptoms had albuminuria more often than individuals without such symptoms, albuminuria may reflect other comorbidity and inflammation conditions than depression.

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The Relationship between Psychological Distress and Coping Strategies in Patients with Advanced or Terminal Stage Hepatocellular Carcinoma: A Cross-Sectional Descriptive Study

Songklanagarind Medical Journal ◽

10.31584/smj.2017.35.4.747 ◽

2017 ◽

Vol 35 (4) ◽

pp. 313

Author(s):

Suthisa Temtap ◽

Kittikorn Nilmanat

Keyword(s):

Hepatocellular Carcinoma ◽

Psychological Distress ◽

Coping Strategies ◽

Depression Scale ◽

Anxiety And Depression ◽

Hospital Anxiety ◽

Cross Sectional ◽

Terminal Stage ◽

And Coping ◽

The Relationship

Objectives: This study was aim to describe the relationship between psychological distress and coping strategies among patients with advanced or terminal stage hepatocellular carcinoma.Material and Method: This is a cross-sectional descriptive study. Data were collect from hospitalized sample at medical units in a tertiary care hospital in southern Thailand during April 2015 - December 2016. Ninety-six sample of advanced or terminal stage hepatocellular carcinoma. Research instruments consisted of 4 parts: (1) a demographic data form, (2) The Karnofsky Performance Status Scale, (3) psychological distress questionnaires using Hospital Anxiety and Depression Scale, and (4) coping strategies questionnaire developed by researchers based on Lazarus and Folkman’s stress and coping theory and literature reviews. Cronbach’s alphas for Hospital Anxiety and Depression Scale and coping strategies questionnaire were 0.89 and 0.84. Data were analyzed using descriptive statistics and Pearson’s product moment correlation coefficient was used.Results: A relationship analysis found that there was a moderate, negative correlation between psychological distress and coping strategies (r=-0.66, p-value<0.001)Conclusion: The results of this study reveal that increases in psychological distress were correlated with decreases in coping strategies among patients with advanced or terminal stage hepatocellular carcinoma. A screening assessment for psychological distress is needed. The results of this study can be used for developing nursing program to promote effective coping strategies among patients with advanced or terminal stage hepatocellular carcinoma to help them live well at the end of life.

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