scholarly journals Herpes zoster infection following mRNA COVID-19 vaccine in a patient with ankylosing spondylitis

Reumatismo ◽  
2021 ◽  
Vol 73 (3) ◽  
Author(s):  
B. Maranini ◽  
G. Ciancio ◽  
R. Cultrera ◽  
M. Govoni
Keyword(s):  
Herpes Zoster ◽  
Ankylosing Spondylitis ◽  
Side Effects ◽  
Severe Acute Respiratory Syndrome ◽  
Virus Reactivation ◽  
Herpes Zoster Infection ◽  
Varicella Zoster ◽  
Injection Site Reactions ◽  
Cutaneous Reactions ◽  
Systemic Manifestations

Since the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic outbreak, vaccines gained a growing role. Possible vaccine-related side effects range from minor local events to more prominent systemic manifestations up to anaphylactic reactions. A heterogeneous spectrum of cutaneous reactions has been reported, ranging from local injection site reactions to urticarial and morbilliform eruptions, pernio/chilblains and zoster flares. Here, we describe a case of varicella zoster virus reactivation following mRNA coronavirus 2019 vaccine and discuss the available literature upon the topic published so far.

scholarly journals Herpes Zoster Infection Presenting as Aseptic Meningitis and Dermatomal Rash in Immunocompetent Adult

2020 ◽  
Vol 2020 ◽  
pp. 1-3 ◽  
Author(s):  
Suyash Dawadi ◽  
Sudesh Lamsal ◽  
Bhupendra Shah
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Aseptic Meningitis ◽  
Elderly Population ◽  
Virus Reactivation ◽  
Herpes Zoster Infection ◽  
Immunocompetent Adult ◽  
Varicella Zoster ◽  
Vesicular Rash ◽  
Immunocompromised Status

Herpes zoster is a localized, painful, and vesicular rash involving one or adjacent dermatomes caused by varicella-zoster virus reactivation. Herpes zoster presenting as aseptic meningitis is prevalent among elderly population and people with immunocompromised status. However, it is a rare phenomenon in the young immunocompetent adult; hence, we are reporting a case of a herpes zoster infection presenting as aseptic meningitis and dermatological manifestation in a 19-year-old immunocompetent male.

scholarly journals Herpes Zoster associated With COVID-19 in an immunocompetent male

2021 ◽  
Vol 11 (2) ◽  
pp. 35-37
Author(s):  
Abdullah Al Faruk ◽  
Mohammad Rifat Rahman
Keyword(s):  
Herpes Zoster ◽  
Severe Acute Respiratory Syndrome ◽  
Maculopapular Rash ◽  
Virus Reactivation ◽  
Varicella Zoster ◽  
Immune Exhaustion ◽  
Pulmonary Manifestations ◽  
Vesicular Rash ◽  
Extra Pulmonary ◽  
Middle Aged Adults

Severe acute respiratory syndrome coronavirus (SARS-COV-2) presented with pulmonary symptoms and various extra pulmonary manifestations including dermatological manifestations like urticarial, acralvascular lesion erythematous maculopapular rash, and vesicular rash. Herpes zoster is a painful vesicular rash resulting from reactivation of varicella-zoster (VZ) virus that also a causative agent of chickenpox. The incidence of HZ infection (HZI) more prevalent in older ages and various immunosuppressive conditions. Coronavirus disease in 2019(Covid19) causing immune exhaustion and VZ virus reactivation, which is commonly presented as HZ in middle-aged adults. Here we report a case of HZ infection in association with COVID 19 positive 60 years male.  Update Dent. Coll. j: 2021; 11(2): 35-37      

scholarly journals Association between statin use and herpes zoster: systematic review and meta-analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. e022897 ◽  
Author(s):  
Lailai Fan ◽  
Yangyang Wang ◽  
Xiang Liu ◽  
Xueqiang Guan
Keyword(s):  
Herpes Zoster ◽  
Meta Analysis ◽  
Random Effect ◽  
Sensitivity Analyses ◽  
Lipid Lowering ◽  
Significant Heterogeneity ◽  
Virus Reactivation ◽  
Herpes Zoster Infection ◽  
Varicella Zoster ◽  
Statin Use

ObjectiveStatins are commonly prescribed worldwide. In addition to being potent lipid-lowering agents, statins have immunomodulating properties that may increase the risk of varicella zoster virus reactivation. This adverse effect may have substantial public health implications.DesignWe performed a meta-analysis of observational studies to assess the association between statin use and the risk of herpes zoster infection. We searched PubMed, Embase, Web of Science and Cochrane databases to identify studies published from 1980 to 2018. The multivariate-adjusted ORs were pooled using random-effect models, and subgroup and sensitivity analyses were performed to examine the source of heterogeneity.ResultSix studies were analysed, with a total of more than two million participants. We determined if the use of statins might increase the risk of infection of herpes zoster (OR 1.18, 95% CI 1.11 to 1. 25). We detected significant heterogeneity (I2=91.2%; p<0.000), and determined that the heterogeneity arises from regional differences.ConclusionThe use of statins may increase the risk of herpes zoster infection. Because the studies included are limited and there may be potential bias, further studies are warranted.

scholarly journals Successful Use of Kidneys from a Deceased Donor with Active Herpes Zoster Infection

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Amanda J. Vinson ◽  
Prakash Chauhan ◽  
Christopher Daley ◽  
Himanthi De Silva ◽  
Karthik K. Tennankore ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Deceased Donor ◽  
Infectious Complications ◽  
Varicella Zoster Virus Infection ◽  
Herpes Zoster Infection ◽  
Donor Pool ◽  
Varicella Zoster ◽  
Organ Retrieval ◽  
Infectious Risk ◽  
Kidney Recipients

Background. The limited donor pool and increasing recipient wait list require a reevaluation of kidney organ suitability for transplantation. Use of higher infectious risk organs that were previously discarded may help improve access to transplantation and reduce patient mortality without placing patients at a higher risk of poor posttransplant outcomes. There is very little data available regarding the safe use of kidney organs from deceased donors with varicella zoster virus infection at the time of organ retrieval. Case Presentation. Here, we report a case of successful transplantation of both kidneys from a deceased donor with active herpes zoster infection at the time of organ retrieval. Recipients were treated preemptively with acyclovir. At 4 months posttransplant, both kidney recipients experienced no infectious complications and were off dialysis with functioning transplant grafts. Conclusions. The use of kidney organs from donors with active herpes zoster infection appears to be a safe option to expand the kidney donor pool.

scholarly journals Varicella Vaccine Meningitis as a Complication of Herpes Zoster in Twice-Immunized Immunocompetent Adolescents

2020 ◽  
Vol 35 (13) ◽  
pp. 889-895 ◽  
Author(s):  
Veena Ramachandran ◽  
Stephen C. Elliott ◽  
Kathie L. Rogers ◽  
Randall J. Cohrs ◽  
Miles Weinberger ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Varicella Vaccine ◽  
The United States ◽  
Vaccine Virus ◽  
Virus Reactivation ◽  
Wild Type ◽  
Varicella Zoster ◽  
Intravenous Acyclovir

Varicella-zoster virus vaccination is recommended for virtually all young children in the United States, Canada, and several other countries. Varicella vaccine is a live attenuated virus that retains some of its neurotropic properties. Herpes zoster caused by vaccine virus still occurs in immunized children, although the rate is much lower than in children who had wild-type varicella. It was commonly thought that 2 varicella vaccinations would protect children against the most serious complication of meningitis following herpes zoster; however, 2 meningitis cases have already been published. We now report a third case of varicella vaccine meningitis and define risk factors shared by all 3 immunized adolescents. The diagnosis in cerebrospinal fluid in this third case was verified by amplifying and sequencing portions of the viral genome, to document fixed alleles found only in the vaccine strain. Viral antibody was also detected in the cerebrospinal fluid by confocal microscopy. When compared with the other 2 cases, remarkably all 3 were 14 years old when meningitis occurred. All 3 were treated with intravenous acyclovir, with complete recovery. The adolescent in our case report also had recurrent asthma, which was treated with both prednisone tablets and beclomethasone inhaler before onset of meningitis. When the 3 cases were considered together, they suggested that immunity to varicella-zoster virus may be waning sufficiently in some twice-immunized adolescents to make them vulnerable to varicella vaccine virus reactivation and subsequent meningitis. This complication rarely happens in children after wild-type varicella.

scholarly journals Recurrent herpes zoster with segmental paresis and postherpetic neuralgia

2014 ◽  
Vol 71 (2) ◽  
pp. 214-217 ◽  
Author(s):  
Vesna Martic
Keyword(s):  
Herpes Zoster ◽  
Postherpetic Neuralgia ◽  
Complete Recovery ◽  
The Body ◽  
Chronic Lymphatic Leukemia ◽  
Virus Reactivation ◽  
Herpes Zoster Infection ◽  
Lymphatic Leukemia ◽  
Recurrent Herpes ◽  
Different Parts

Introduction. Postherpetic neuralgia and segmental paresis represent rare complications of herpes zoster infection. Recurrent herpes zoster is also rare and occurs within the first 3 years of the begining of the illness in only 1.4% of cases but it is generally higher in cases of chronic lymphatic leukemia (3.5%). Case report. We presented a patient with lymphatic leukemia who during the remission had 3 episodes of herpes zoster over a year. All of them took different parts of the body. One of these episodes was complicated by postherpetic neuralgia and segmental paresis. A complete recovery was seen in all the three episodes. Conclusion. As immunosuppression is one of mechanisms of virus reactivation, it is likely associated with the described rare complications of herpes zoster.

scholarly journals Orofacial Herpes Zoster Infection in Dental practice: A Case Report

2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Deepa Gurung ◽  
Ujjwal Joshi ◽  
Bikash Chaudhary
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Trigeminal Nerve ◽  
Maculopapular Rash ◽  
Dental Practice ◽  
Herpes Zoster Infection ◽  
Prodromal Symptoms ◽  
Varicella Zoster ◽  
Burning Pain ◽  
Ophthalmic Branch

Herpes zoster infection, commonly known as Shingles, is caused by reactivation of the Varicella-Zoster virus which may have remained latent in the dorsal root ganglia. HZI is characterized by prodromal symptoms of unilateral deep aching, burning pain followed by a maculopapular rash, vesicular eruptions, ulcers, and scab formations over the affected nerve distribution. The ophthalmic branch of the trigeminal nerve is more commonly involved in HZI than maxillary and mandibular branches; in particular, the maxillary involvement is rare. This is a case report of HZI in a 65-years-old male patient involving the maxillary division of the trigeminal nerve. This case highlights the importance of early diagnosis and prompt use of antivirals in managing orofacial HZI in dental practice.

scholarly journals Rare Occurrence of Herpes Zoster of Trigeminal Nerve following Extraction of Tooth

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
A. Winnifred Christy ◽  
T. Jones Raja Deva Thanmbi ◽  
J. Leelavathy ◽  
Antoinette Rhema Louis
Keyword(s):  
Herpes Zoster ◽  
Viral Infection ◽  
Varicella Zoster Virus ◽  
Medical History ◽  
Male Patient ◽  
Clinical Examination ◽  
Rare Occurrence ◽  
Herpes Zoster Infection ◽  
Varicella Zoster ◽  
Acute Viral Infection

Herpes Zoster also known as Shingles is an acute viral infection which is an extremely painful and incapacitating ailment. It results from the reactivation of the varicella zoster virus. The triggering factors for the onset of an attack of Herpes Zoster include some form of immunosuppression. The diagnosis of Herpes Zoster can be made on proper medical history and a thorough clinical examination. Here is the report of a male patient affected by Herpes Zoster infection which followed after extraction of a lower first molar.

scholarly journals Topical (S)-ketamine for pain management of postherpetic neuralgia

2012 ◽  
Vol 87 (3) ◽  
pp. 504-505 ◽  
Author(s):  
Guilherme Antonio Moreira de Barros ◽  
Hélio Amante Miot ◽  
Ademir Massarico Braz ◽  
Flávia Ramos ◽  
Marcos Aristoteles Borges
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Herpes Zoster ◽  
Postherpetic Neuralgia ◽  
Statistical Difference ◽  
Topical Administration ◽  
Herpes Zoster Infection ◽  
Pain Scores ◽  
Cutaneous Reactions ◽  
Prolonged Pain

Herpes zoster infection may cause postherpetic neuralgia, which is defined by prolonged pain predominantly mediated by central nervous system hypersensitivity. This phenomenon may be reversed by (S)-ketamine (SKET), but its use results in intolerable side effects, while its topical administration seems to be safe. It is a cross-over design study with 12 patients randomly divided into two groups. There was a significant effect of time on pain intensity, but no statistical difference in pain scores for SKET or placebo use in this sample in this treatment regimen. Only few mild cutaneous reactions were observed with topical SKET use.

Disseminated herpes zoster with acute encephalitis in an immunocompetent elderly man

2020 ◽  
Vol 13 (6) ◽  
pp. e232928
Author(s):  
Jessica Hyejin Oh ◽  
Saketh Tummala ◽  
Muhammad Ghazanfar Husnain
Keyword(s):  
Differential Diagnosis ◽  
Herpes Zoster ◽  
Immunocompetent Patient ◽  
Elevated Risk ◽  
Herpes Zoster Infection ◽  
Varicella Zoster ◽  
Healthy Elderly ◽  
Acute Encephalitis ◽  
Ischaemic Attack ◽  
Precipitating Factor

Varicella-zoster virus (VZV) encephalitis typically occurs in immunosuppressed populations such as in patients with HIV/AIDS, transplantation and autoimmune disease. However, it can also occur in healthy hosts. We present the case of an immunocompetent patient who presented with a clinical picture of VZV encephalitis with the sole precipitating factor of advanced age. We want to stress the importance of including VZV in the differential diagnosis for encephalitis in healthy elderly hosts. In patients with a clinical diagnosis of encephalitis, the presence of herpes zoster rash increases the likelihood of VZV encephalitis. However, the absence of a skin rash may not exclude the diagnosis. In general, there is an elevated risk of transient ischaemic attack and stroke associated with the diagnosis of herpes zoster infection. Early treatment is essential to prevent complications, including death.

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