The Interaction between Remifentanil and Propofol during Total Intravenous Anesthesia and the Adequate Effect Site Concentration

2008 ◽  
Vol 54 (2) ◽  
pp. 139 ◽  
Author(s):  
Won Ho Kim ◽  
Hyun Joo Ahn
Keyword(s):  
Total Intravenous Anesthesia ◽  
Intravenous Anesthesia ◽  
Effect Site ◽  
Effect Site Concentration

Practicalities of Total Intravenous Anesthesia and Target-controlled Infusion in Children

2019 ◽  
Vol 131 (1) ◽  
pp. 164-185 ◽  
Author(s):  
Brian J. Anderson ◽  
Oliver Bagshaw
Keyword(s):  
Total Intravenous Anesthesia ◽  
Parameter Estimates ◽  
Intravenous Anesthesia ◽  
Effect Site ◽  
Target Controlled Infusion ◽  
Effect Site Concentration ◽  
Smart Pumps ◽  
Surgical Stimulation ◽  
Two Parameter ◽  
Type Of Surgery

AbstractPropofol administered in conjunction with an opioid such as remifentanil is used to provide total intravenous anesthesia for children. Drugs can be given as infusion controlled manually by the physician or as automated target-controlled infusion that targets plasma or effect site. Smart pumps programmed with pharmacokinetic parameter estimates administer drugs to a preset plasma concentration. A linking rate constant parameter (keo) allows estimation of effect site concentration. There are two parameter sets, named after the first author describing them, that are commonly used in pediatric target-controlled infusion for propofol (Absalom and Kataria) and one for remifentanil (Minto). Propofol validation studies suggest that these parameter estimates are satisfactory for the majority of children. Recommended target concentrations for both propofol and remifentanil depend on the type of surgery, the degree of surgical stimulation, the use of local anesthetic blocks, and the ventilatory status of the patient. The use of processed electroencephalographic monitoring is helpful in pediatric total intravenous anesthesia and target-controlled infusion anesthesia, particularly in the presence of neuromuscular blockade.

scholarly journals Total Intravenous Anesthesia in Neurosurgery

2018 ◽  
Vol 05 (03) ◽  
pp. 141-149 ◽  
Author(s):  
Narmadhalakshmi Kannabiran ◽  
Prasanna Udupi Bidkar
Keyword(s):  
Postoperative Nausea And Vomiting ◽  
Total Intravenous Anesthesia ◽  
Intravenous Anesthesia ◽  
Anesthetic Agents ◽  
Nociceptive Stimulus ◽  
Neurosurgical Patients ◽  
Effect Site Concentration ◽  
Safe Anesthesia ◽  
Infusion Technique ◽  
Rapid Emergence

AbstractIn recent years, neurosurgical anesthesia has been rapidly evolving in the fields of pharmacotherapy and techniques to administer safe anesthesia. Intravenous (IV) anesthetic agents reduce both cerebral blood flow and intracranial pressure besides maintaining flow–metabolism coupling in contrast to inhalational agents. In neuroanesthesia, the technique and choice of drugs directly influence the outcome of the patients. The purpose of this review is to provide the updated information of total intravenous anesthesia (TIVA) in neuroanesthesia. Administration of TIVA using target-controlled infusion technique is emerging as a standard method to administer safe anesthesia in neurosurgical patients. The propofol–remifentanil combination has become very popular due to their favorable pharmacokinetic and pharmacodynamic properties for neurosurgery cases. Plasma-effect site concentration monitoring from target TCI devices together with electroencephalogram or bispectral index monitors allows easy titration of anesthetic agents to ensure adequate depth of anesthesia depending upon the nociceptive stimulus. TIVA is associated with smooth induction and rapid emergence with less postoperative nausea and vomiting.

Analysis of Parameters Determining the Frequency and Intensity of Pneumatocele in Patients with CPA Tumor Operated in Sitting Position with Total Intravenous Anesthesia

Skull Base ◽  
2007 ◽  
Vol 17 (S 1) ◽  
Author(s):  
Stanislaw Kwiek ◽  
Hanna Doleżych ◽  
Wojciech Ślusarczyk ◽  
Piotr Bażowski ◽  
Izabela Duda ◽  
...  
Keyword(s):  
Total Intravenous Anesthesia ◽  
Sitting Position ◽  
Intravenous Anesthesia

Total Intravenous Anesthesia pada Geriatri dengan Meningioma Parietalis

2015 ◽  
Vol 4 (2) ◽  
pp. 112-118
Author(s):  
Rebecca Sidhapramudita Mangastuti ◽  
◽  
Nazaruddin Umar ◽  
Marsudi Rasman ◽  
◽  
...  
Keyword(s):  
Total Intravenous Anesthesia ◽  
Intravenous Anesthesia

Total Intravenous Anesthesia pada Geriatri dengan Meningioma Parietalis

2015 ◽  
Vol 4 (2) ◽  
pp. 112-18
Author(s):  
Rebecca Sidhapramudita Mangastuti ◽  
◽  
Nazaruddin Umar ◽  
Marsudi Rasman ◽  
◽  
...  
Keyword(s):  
Total Intravenous Anesthesia ◽  
Intravenous Anesthesia
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