scholarly journals Effects of Areca nut extracts on the neutrophil functions in blood and saliva samples of subjects with normal oral mucosa with and without Areca nut habit: A comparative study

2020 ◽  
Vol 9 (3) ◽  
pp. 183
Author(s):  
VijayalakshmiS Kotrashetti ◽  
V Chandrarekha ◽  
KishoreG Bhat ◽  
Deepa Babji
Author(s):  
S.I. Kutukova ◽  
A.B. Chukhlovin ◽  
A.I. Yaremenko ◽  
Yu.V. Ivaskova ◽  
A.Ya. Razumova ◽  
...  

The aim of the study was to assess the prevalence of DNA viruses (HSV I and II, CMV, EBV, HPV6.11, HPV16 and HPV18) in the native oral mucosa of healthy volunteers (n=50; 30 men (60.0%), 20 women (40.0%); 25—74 years, median age — 55.0 years (95% CI 47.60-56.76)). All samples of the normal oral mucosa were detected by real-time PCR to detect viral DNA. The majority of the examined — 76% (33/50) — revealed the DNA: one type of viral DNA in 17 (38.00%) of the examined, a combination of the two types in 14 (28.00%). In the normal oral mucosa, DNA of Epstein-Barr virus was significantly more often detected: 15 (30.00%) (p = 0.0276) and human papilloma viruses 27 (54.00%) (p <0.0001), especially HPV-18 (24 (48.00%)): mono-association in 9 (18.00%) examined and in 7 (14.00%) in combination with EBV DNA (p = 0.0253).


Oral Diseases ◽  
2008 ◽  
Vol 6 (2) ◽  
pp. 118-123 ◽  
Author(s):  
CM Healy ◽  
AT Cruchley ◽  
MH Thornhill ◽  
DM Williams

Author(s):  
Maria del Refugio González-Losa ◽  
Luis Manzano-Cabrera ◽  
Florencio Rueda-Gordillo ◽  
Sandra E. Hernández-Solís ◽  
Marylin Puerto-Solís

2016 ◽  
Vol 6 (12) ◽  
pp. 1013-1017
Author(s):  
G Dundy ◽  
H Kumar ◽  
A Singh ◽  
A Chandarakant

Background: Mutation of p53 gene is one of the most common events in oral carcinogenesis. Accumulation of p53 protein has also been detected in premalignant lesions.Materials and Methods:  This study included 40 biopsy samples, which were received in department of pathology, Sarojini Naidu Medical College, Agra, to ascertain p53 expression by immunohistochemically, in patients with oral squamous cell carcinomas and to correlate its expression with histological grade, different sites in oral cavity and tobacco intake/smoking habits.Results: Out of 40 biopsies of oral mucosa, 03 showed normal oral mucosa and 37 were diagnosed as squamous cell carcinoma (SCC), most patients were in 5th and 6th decade and majority (86.5%) of oral SCC were males with buccal mucosa being the most common site. There was a statistically significant difference in p53 expression between oral SCC and normal oral mucosa (p value <0.05). Of total 37 cases, 12 cases were well differentiated type, 16 moderately differentiated and 09 of poorly differentiated type of SCC. In each category, about two thirds were positive for p53 staining. Out of total 37 cases of oral SCC, 64.9% were positive and 35.1% were negative for p53 expression, 34 cases had positive history of tobacco intake/smoking habits, of which 23 cases were positive while 11 cases were negative for p53 staining.Conclusion: Abnormal p53 protein was detected in 64.9% of oral squamous cell carcinoma, but not in normal oral mucosa. p53 expression was associated with malignant transformation of oral mucosa. 


2015 ◽  
Vol 6 (2) ◽  
pp. 148 ◽  
Author(s):  
RUma Devi ◽  
Raghu Dhanapal ◽  
K Ranganathan ◽  
Paturu Kondaiah ◽  
Elizabeth Joshua ◽  
...  

1992 ◽  
Vol 24 (12) ◽  
pp. 964-968 ◽  
Author(s):  
A. E. Schwint ◽  
A. M. Collet ◽  
A. E. Mendez ◽  
R. L. Cabrini ◽  
M. E. Itoiz

Author(s):  
Y. Sugiyama ◽  
S. Ishibashi ◽  
H. Furuuchi ◽  
H. Iwabuchi ◽  
T. Sawada ◽  
...  

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