scholarly journals Effect of National Oral Health Screening Program on the Risk of Head and Neck Cancer: A Korean National Population-Based

Author(s):  
Chan Woo Wee ◽  
Hyo-Jung Lee ◽  
Jae-Ryun Lee ◽  
Hyejin Lee ◽  
Min-Jeong Kwoen ◽  
...  
2020 ◽  
Author(s):  
Ho Geol Woo ◽  
Kijeong Lee ◽  
Ji Sung Lee ◽  
Jinkwon Kim ◽  
Younkyung Chang ◽  
...  

Abstract Background: In previous case-control and cross-sectional studies, less frequent dental visits, infrequent tooth brushing, presence of periodontal disease, and increased number of tooth loss were shown to be associated with increased risk of head and neck cancer. However, studies regarding the association of periodontal disease and parameters of oral health with occurrence of head and neck cancer have been lacking particularly in longitudinal setting. We aimed to investigate the relationship between parameters of oral health and risk of head and neck cancer in a nationwide general population-based cohort.Methods : We included 150,774 subjects from the Korean National Health Insurance System-Health Screening Cohort for demographics, past history, and laboratory findings. The presence of periodontal disease and parameters of oral health including frequency of tooth brushings, dental visit for any reason, expertised dental cleaning, and number of tooth loss were investigated. Head and neck cancer was defined as International Statistical Classification of Diseases-10 codes of ‘C00-C14’.Results: During median 11.1 years of follow-up, 1,155 (0.76%) head and neck cancers occurred. Based on multivariable analysis, after adjusting for demographics, alcohol intake, smoking, regular exercise, body mass index, systolic blood pressure, blood and urinary laboratory findings, and parameters of oral health, frequent tooth brushing (more than three times per day) was related to lower risk of head and neck cancer (hazard ratio, HR: 0.78, 95% confidence interval, CI: 0.66–0.93, p=0.005). Increased number of tooth loss was positively associated with occurrence of head and neck cancer (p value for trend test for HR <0.001).Conclusions : The occurrence of head and neck cancer was decreased with the more frequent tooth brushing (more than three times per day) and increased with the number of tooth loss. In regards of head and neck cancer prevention, improving oral hygiene may have significant contribution.


2019 ◽  
Vol 58 (10) ◽  
pp. 1509-1513 ◽  
Author(s):  
Louise Hill-Madsen ◽  
Claus A. Kristensen ◽  
Elo Andersen ◽  
Jørgen Johansen ◽  
Lisbeth J. Andersen ◽  
...  

2021 ◽  
Vol 5 (1) ◽  
pp. 23
Author(s):  
Raquel Pacheco ◽  
Maria Alzira Cavacas ◽  
Paulo Mascarenhas ◽  
Pedro Oliveira ◽  
Carlos Zagalo

This systematic review and meta-analysis aimed to assess the literature about the incidence of oral mucositis and its degrees (mild, moderate, and severe), in patients undergoing head and neck cancer treatment (radiotherapy, chemotherapy, and surgery). Addressing this issue is important since oral mucositis has a negative impact on oral health and significantly deteriorates the quality of life. Therefore, a multidisciplinary team, including dentists, should be involved in the treatment. The overall oral mucositis incidence was 89.4%. The global incidence for mild, moderate, and severe degrees were 16.8%, 34.5%, and 26.4%, respectively. The high incidence rates reported in this review point out the need for greater care in terms of the oral health of these patients.


Author(s):  
Rosanne C. Schoonbeek ◽  
Dominique V.C. de Jel ◽  
Boukje A.C. van Dijk ◽  
Stefan M. Willems ◽  
Elisabeth Bloemena ◽  
...  

PLoS ONE ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. e0229266 ◽  
Author(s):  
Christoph Evers ◽  
Christian Ostheimer ◽  
Frank Sieker ◽  
Dirk Vordermark ◽  
Daniel Medenwald

2020 ◽  
Vol 34 (5) ◽  
pp. 639-650 ◽  
Author(s):  
Catriona R Mayland ◽  
Kate Ingarfield ◽  
Simon N Rogers ◽  
Paola Dey ◽  
Steven Thomas ◽  
...  

Background: Few large studies describe initial disease trajectories and subsequent mortality in people with head and neck cancer. This is a necessary first step to identify the need for palliative care and associated services. Aim: To analyse data from the Head and Neck 5000 study to present mortality, place and mode of death within 12 months of diagnosis. Design: Prospective cohort study. Participants: In total, 5402 people with a new diagnosis of head and neck cancer were recruited from 76 cancer centres in the United Kingdom between April 2011 and December 2014. Results: Initially, 161/5402 (3%) and 5241/5402 (97%) of participants were treated with ‘non-curative’ and ‘curative’ intent, respectively. Within 12 months, 109/161 (68%) in the ‘non-curative’ group died compared with 482/5241 (9%) in the ‘curative’ group. Catastrophic bleed was the terminal event for 10.4% and 9.8% of people in ‘non-curative’ and ‘curative’ groups, respectively; terminal airway obstruction was recorded for 7.5% and 6.3% of people in the same corresponding groups. Similar proportions of people in both groups died in a hospice (22.9% ‘non-curative’; 23.5% ‘curative’) and 45.7% of the ‘curative’ group died in hospital. Conclusion: In addition to those with incurable head and neck cancer, there is a small but significant ‘curative’ subgroup of people who may have palliative needs shortly following diagnosis. Given the high mortality, risk of acute catastrophic event and frequent hospital death, clarifying the level and timing of palliative care services engagement would help provide assurance as to whether palliative care needs are being met.


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