scholarly journals Clinical Features and the Diagnostic Value of Component Allergen-Specific IgE in Hymenoptera Venom Allergy

2012 ◽  
Vol 4 (5) ◽  
pp. 284 ◽  
Author(s):  
Yoo Seob Shin ◽  
Jing Nan Liu ◽  
Gyu-Young Hur ◽  
Eui-Kyung Hwang ◽  
Young Hee Nam ◽  
...  
Keyword(s):  
Clinical Features ◽  
Specific Ige ◽  
Diagnostic Value ◽  
Hymenoptera Venom ◽  
Venom Allergy ◽  
Hymenoptera Venom Allergy

Stinging Insect Allergens

2020 ◽  
Vol 21 (2) ◽  
pp. 142-152 ◽  
Author(s):  
Le Cui ◽  
Ying-Yang Xu ◽  
Xiu-Jie Wang ◽  
Kai Guan
Keyword(s):  
Specific Ige ◽  
Cross Reactivity ◽  
Hymenoptera Venom ◽  
Venom Allergy ◽  
Hymenoptera Venom Allergy ◽  
Predictive Values ◽  
Common Causes ◽  
History Of ◽  
The Common ◽  
Stinging Insect

Hymenoptera venom allergy is one of the common causes of anaphylaxis. However, when physicians make the diagnosis of Hymenoptera venom allergy, the history of being stung is not always consistent with the results of venom-specific IgE. With the development of component-resolved diagnosis, it is possible to accurately localize an allergic reaction to certain sensitized proteins. This paper reviewed the studies that have addressed the identified allergenicity and cross-reactivity of Hymenoptera venom allergens accepted by the WHO/IUIS Nomenclature Sub-committee, the componentresolved diagnosis of Hymenoptera venom allergy and its predictive values for the efficacy and safety of venom immunotherapy. Also special attention was paid to the spread of Hymenoptera venom allergy in Asian countries.

scholarly journals Hymenoptera venom allergy in outdoor workers: Occupational exposure, clinical features and effects of allergen immunotherapy

2016 ◽  
Vol 13 (2) ◽  
pp. 477-483 ◽  
Author(s):  
Alessandra Toletone ◽  
Susanna Voltolini ◽  
Giovanni Passalacqua ◽  
Guglielmo Dini ◽  
Donatella Bignardi ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
Clinical Features ◽  
Allergen Immunotherapy ◽  
Hymenoptera Venom ◽  
Venom Allergy ◽  
Hymenoptera Venom Allergy ◽  
Outdoor Workers

The role of component-resolved diagnosis in Hymenoptera venom allergy in clinical practice

2021 ◽  
Vol 42 (4) ◽  
pp. 350-356 ◽  
Author(s):  
Ayse Engin ◽  
Fatma B. Oktelik ◽  
Aslı Gelincik ◽  
Aytul Sin ◽  
Betul A. Sin ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Specific Ige ◽  
Cross Reactivity ◽  
Bee Venom ◽  
Skin Tests ◽  
Hymenoptera Venom ◽  
Venom Allergy ◽  
Hymenoptera Venom Allergy ◽  
Conventional Tests ◽  
Bee Venom Allergy

Background: Hymenoptera venom allergy is an immunoglobulin (Ig) E mediated hypersensitivity reaction to Hymenoptera venoms. Obvious identification of the culprit insect that causes the clinical symptoms and, hence, the accurate selection of venom for curative treatment, is of great importance for the effectiveness and safety of venom immunotherapy. Objective: In this study, the contribution of component-resolved diagnostics (CRD) is evaluated in the diagnosis of Hymenoptera venom allergy. Method: Ninety-three patients from four different centers in Turkey were included in the study. Conventional tests, including prick and intradermal skin tests, with commercial venom extracts and serum specific IgE (sIgE) levels for whole venoms were performed. An sIgE analysis for venom allergen components, including rApi m 1, rApi m 2, rApi m 10, rVes v 1, rVes v 5, were evaluated by immunoblotting. Results: In conventional test results, 17 of 35 patients with bee venom allergy were positive to honey bee venom, whereas 18 patients were positive to bee and wasp venoms. In 28 of 35 patients with bee venom allergy, the diagnosis was confirmed with CRD. CRD revealed a sensitivity of 80% in patients with bee venom allergy. According to conventional tests, 7 of 24 patients with vespid venom allergy demonstrated sensitivity only to Vespula species, whereas 17 patients revealed double positivity. The total diagnostic sensitivity of Ves v 1 and Ves v 5 was calculated as 87.5%. Ten of 23 patients with a history of hypersensitivity to both venoms showed double sensitivity with CRD; one patient had cross-reactivity, one patient was found to be sensitive only to bee venom, and, eight patients were sensitive only to Vespula species. Eleven patients had an uncertain history in terms of the culprit insect type and six of them had double sensitivity in CRD. Conclusion: CRD seemed to be more helpful in diagnosing vespid venom allergy than bee venom allergy. It can also discriminate clinically significant sensitizations from irrelevant ones.

Hymenoptera Venom Allergy: Time Course of Specific IgE Concentrations during the First Weeks after a Sting

1999 ◽  
Vol 120 (2) ◽  
pp. 166-168 ◽  
Author(s):  
Verena Rieger-Ziegler ◽  
Edgar Rieger ◽  
Birger Kränke ◽  
Werner Aberer
Keyword(s):  
Time Course ◽  
Specific Ige ◽  
Hymenoptera Venom ◽  
Venom Allergy ◽  
Hymenoptera Venom Allergy

scholarly journals 88 Clinical Features and Diagnostic Value of Specific IGE to Component Allergen in Bee Venom Allergy in Korea

2012 ◽  
Vol 5 ◽  
pp. S29
Author(s):  
Yoo Seob Shin ◽  
Jing Nan Liu ◽  
Gyu-Young Hur ◽  
Eui-kyung Hwang ◽  
Young-Hee Nam ◽  
...  
Keyword(s):  
Clinical Features ◽  
Specific Ige ◽  
Diagnostic Value ◽  
Bee Venom ◽  
Venom Allergy ◽  
Bee Venom Allergy
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