scholarly journals Endoscopic balloon dilation for management of stricturing Crohn’s disease in children

2021 ◽  
Vol 13 (9) ◽  
pp. 382-390
Author(s):  
Brianna McSorley ◽  
Robert A Cina ◽  
Candi Jump ◽  
Johanna Palmadottir ◽  
J Antonio Quiros
2021 ◽  
Vol 34 (04) ◽  
pp. 227-232
Author(s):  
Molly M. Ford

AbstractObstruction from stricturing Crohn's disease remains one of the most common reasons for intervention. Acute inflammation is often responsive to medications, but chronic fibrosis is unlikely to respond and will generally go on to require additional treatment. Newer methods, such as endoscopic balloon dilation, are gaining grounds in strictures that are amenable, but with high recurrence and strictures that may not be endoscopically accessible, surgery still plays a key role in the treatment of obstructing Crohn's disease.


2019 ◽  
Vol 95 (1) ◽  
pp. 72-74
Author(s):  
Yusuke Sakurai ◽  
Hirotsugu Sakamoto ◽  
Tomonori Yano ◽  
Keijiro Sunada ◽  
Hironori Yamamoto

2009 ◽  
Vol 136 (5) ◽  
pp. A-656-A-657
Author(s):  
Daniela Scimeca ◽  
Filippo Mocciaro ◽  
Ambrogio Orlando ◽  
Luigi M. Montalbano ◽  
Gennaro D'Amico ◽  
...  

2011 ◽  
Vol 140 (5) ◽  
pp. S-140
Author(s):  
Anders Gustavsson ◽  
Anders Magnuson ◽  
Björn Blomberg ◽  
Magnus Andersson ◽  
Jonas Halfvarson ◽  
...  

2019 ◽  
Vol 14 (4) ◽  
pp. 557-566 ◽  
Author(s):  
Iago Rodríguez-Lago ◽  
Javier P Gisbert

Abstract Crohn’s disease is a progressive and disabling inflammatory disease involving the gastrointestinal tract. It usually produces inflammatory lesions in the ileocolonic region, but up to half of patients will also develop complications such as strictures in the long term. Indeed, a proportion of patients have progression of the disease with the development of stricturing lesions because there are no drugs that effectively prevent or reverse established fibrosis, and hence these patients are usually treated with surgery or endoscopic balloon dilation. Fibrotic lesions are always associated with some degree of inflammatory changes, but there is little evidence supporting the use of medical therapy in this context. Here, we discuss the most important findings on the possible use of immunomodulators or biologics in the prevention and treatment of intestinal strictures in Crohn’s disease patients. Recent evidence demonstrates that these drugs may also be effective in treating lesions with high levels of collagen deposition, and thus might, at least in some patients, reduce the progression of the disease and bowel damage, and further avoid the need for surgery and a disabling course in the long term.


Sign in / Sign up

Export Citation Format

Share Document