Comparison of characteristics and ventilatory course between coronavirus disease 2019 and middle east respiratory syndrome patients with acute respiratory distress syndrome

Venous Thromboembolism ◽

Middle East ◽

Severe Acute Respiratory Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Middle East Respiratory Syndrome ◽

D Dimer

Severe acute respiratory syndrome coronavirus (SARS-CoV-2) merupakan famili dari coronavirus, sudah dua kali menyababkan kejadian luar biasa yaitu di tahun 2003 dengan SARS (Severe Acute Respiratory Syndrome) dan tahun 2012 dengan penyakit MERS (Middle East Respiratory Syndrome). Pada tahun 2019 SARS-CoV-2 telah menyebabkan pandemi global kembali. Pertama kali diidentifikasi di Wuhan, Cina. Dan telah menyebar ke seluruh negara dengan jumlah kasus yang terus meningkat secara eksponensial diseluruh dunia. Pada Maret 2020 oleh WHO dinyatakan pandemic. (Covid-19), menyebabkan pneumonia dan beberapa kondisi dapat terjadi Acute Respiratory Distress Syndrome (ARDS) serta beberapa manifestasi ekstra paru, seperti kardiovaskular, saluran cerna, ginjal ,hematologi, sekuele akibat trombosis dan progresifitas disfungsi organ.1 Prognosis pada pasien Covid-19 salah satu tanda ,gejalanya adalah terjadinya gangguan koagulasi, yang ditandai dengan meningkatnya nilai D dimer sebagai tanda awal kondisi thrombosis dan salah satunya dapat bermanifestasi sebagai Venous Thromboembolism (VTE). Pada pasien dengan Covid-19, kondisi koagulopati adalah salah satu kunci dan tanda persisten yang terkait dengan outcome yang buruk.1,2

Intubation and mechanical ventilation of patients with COVID-19: what should we tell them?

Monaldi Archives for Chest Disease ◽

10.4081/monaldi.2020.1296 ◽

2020 ◽

Vol 90 (1) ◽

Cited By ~ 1

Author(s):

Nicholas Zareifopoulos ◽

Maria Lagadinou ◽

Anastasia Karela ◽

Gerasimos Karantzogiannis ◽

Dimitrios Velissaris

Keyword(s):

Mechanical Ventilation ◽

Informed Consent ◽

Middle East ◽

Severe Acute Respiratory Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Middle East Respiratory Syndrome

Severe COVID-19 illness is characterised by the development of Acute Respiratory Distress Syndrome (ARDS), for which the mainstay of treatment is represented by mechanical ventilation. Mortality associated with ARDS due to other causes is in the range of 40-60%, but currently available data are not yet sufficient to draw safe conclusions on the prognosis of COVID-19 patients who require mechanical ventilation. Based on data from cohorts of the related coronavirus-associated illnesses, that is to say Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), prognosis would seem to be worse than ARDS due to other causes such as trauma and other infections. Discussion of prognosis is central to obtaining informed consent for intubation, but in the absence of definitive data it is not clear exactly what this discussion should entail.

COVID 19 and its management

Asian Journal of Pharmaceutical Research ◽

10.52711/2231-5691.2021.00022 ◽

2021 ◽

pp. 117-121

Author(s):

Subhashis Debnath ◽

Runa Chakravorty ◽

Donita Devi

Keyword(s):

Public Health ◽

Middle East ◽

Severe Acute Respiratory Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

The Elderly ◽

Public Health Emergency ◽

Novel Coronavirus

In December 2019, severe acute respiratory syndrome-coronavirus-2, a novel coronavirus, initiated an outbreak of pneumonia from Wuhan in China, which rapidly spread worldwide. The outbreak was declared as “a public health emergency of international concern” by the WHO on January 30, 2020, and as a pandemic on March 11, 2020. The disease is transmitted by inhalation or contact with infected droplets and the incubation period ranges from 2 to 14 d. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, malaise among others. The disease is mild in most people; in some (usually the elderly and those with comorbidities), it may progress to pneumonia, acute respiratory distress syndrome (ARDS) and multi organ dysfunction. Many people are asymptomatic. The virus spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower fatality.

Critical Illness Polyneuropathy and Myopathy in Patients With Acute Respiratory Distress Syndrome

Yearbook of Pulmonary Disease ◽

10.1016/s8756-3452(08)70229-9 ◽

2006 ◽

Vol 2006 ◽

pp. 283-284

Author(s):

J.A. Barker

Keyword(s):

Critical Illness ◽

Respiratory Distress ◽

Distress Syndrome ◽

Critical Illness Polyneuropathy

Acute Respiratory Distress Syndrome

10.1017/cbo9780511575112 ◽

1999 ◽

Keyword(s):

Respiratory Distress ◽

Distress Syndrome

COVID-19 – eine vaskuläre Systemerkrankung

Der Klinikarzt ◽

10.1055/a-1261-8676 ◽

2020 ◽

Vol 49 (10) ◽

pp. 418-421

Author(s):

Christopher Werlein ◽

Peter Braubach ◽

Vincent Schmidt ◽

Nicolas J. Dickgreber ◽

Bruno Märkl ◽

...

Keyword(s):

Respiratory Distress ◽

Distress Syndrome

ZUSAMMENFASSUNGDie aktuelle COVID-19-Pandemie verzeichnet mittlerweile über 18 Millionen Erkrankte und 680 000 Todesfälle weltweit. Für die hohe Variabilität sowohl der Schweregrade des klinischen Verlaufs als auch der Organmanifestationen fanden sich zunächst keine pathophysiologisch zufriedenstellenden Erklärungen. Bei schweren Krankheitsverläufen steht in der Regel eine pulmonale Symptomatik im Vordergrund, meist unter dem Bild eines „acute respiratory distress syndrome“ (ARDS). Darüber hinaus zeigen sich jedoch in unterschiedlicher Häufigkeit Organmanifestationen in Haut, Herz, Nieren, Gehirn und anderen viszeralen Organen, die v. a. durch eine Perfusionsstörung durch direkte oder indirekte Gefäßwandschädigung zu erklären sind. Daher wird COVID-19 als vaskuläre Multisystemerkrankung aufgefasst. Vor dem Hintergrund der multiplen Organmanifestationen sind klinisch-pathologische Obduktionen eine wichtige Grundlage der Entschlüsselung der Pathomechanismen von COVID-19 und auch ein Instrument zur Generierung und Hinterfragung innovativer Therapieansätze.