scholarly journals GASTROINTESTINAL TRACT MULTIPLE LYMPHOMATOUS POLYPOSIS PRESENTED AS MANTLE CELL LYMPHOMA

2019 ◽  
Vol 6 (3) ◽  
pp. 80-84
Author(s):  
Fatih Erkan Akay ◽  
Nuray Can ◽  
Mert Cezik ◽  
Hakkı Onur Kırkızlar ◽  
Fatma Selin Soyluoğlu ◽  
...  
2004 ◽  
Vol 39 (10) ◽  
pp. 995-1000 ◽  
Author(s):  
Satoru Tamura ◽  
Koji Ohkawauchi ◽  
Yuichi Yokoyama ◽  
Yoshifumi Higashidani ◽  
Masanori Daibata ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Fady Daniel ◽  
Hazem I. Assi ◽  
Walid Karaoui ◽  
Jean El Cheikh ◽  
Sami Bannoura ◽  
...  

Mantle cell lymphoma (MCL) is a subtype of non-Hodgkin’s lymphoma (NHL) comprising around 7% of adult NHL. It is characterized by a chromosomal translocation t(11:14) and overexpression of Cyclin D1. The incidence of secondary gastrointestinal tract involvement in MCL ranges from 10 to 28% in various series. However primary gastrointestinal MCL is very rare, accounting for only 1 to 4% of primary gastrointestinal lymphomas. The most common endoscopic feature of primary intestinal MCL is multiple lymphomatous polyposis. In rare cases it presents as protruded lesions or superficial lesions. Single colonic mass presentation is an extremely infrequent presentation. MCL has an aggressive course with quick progression, and most cases are discovered in the advanced stages. Colonic biopsies with histologic examination and specific immunohistochemical staining are the gold standard for a proper diagnosis. We report a case of a single mass forming mantle cell lymphoma of the ascending colon in a 57-year-old female patient with unusual colonoscopic and radiologic features and describe the therapy the patient received, thereby adding to the spectrum of clinical presentations of this aggressive lymphoproliferative disorder.


1996 ◽  
Vol 10 (3) ◽  
pp. 144-148
Author(s):  
Hugh James Freeman

A74-year-old male with a history of a tonsillar lymphoma developed diarrhea. Investigations led to detection of extensive intestinal lymphomatous polyposis (mantle cell lymphoma). After an aggressive clinical course with associated nodal and peripheral blood involvement, death followed within three months. Postmortem studies revealed widespread dissemination within the entire gastrointestinal tract, including the esophagus, stomach, and small and large intestines. Although this type of lymphoma is rare and accounts for only about 1% to 8% of all forms of primary B cell gastrointestinal lymphomas in North America, separation from other subtypes has become more important because of reported responses of mucosa-associated lymphoid tissue-lymphomas to antibiotics aimed atHelicobacter pylorieradication.


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