scholarly journals Prevalence and determinants of asphyxia neonatorum among live births at Debre Tabor General Hospital, North Central Ethiopia: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
pp. 385-96
Author(s):  
Wubet Alebachew Bayih ◽  
Tadesse Gashaw Tezera ◽  
Abebaw Yeshambel Alemu ◽  
Demeke Mesfin Belay ◽  
Habtamu Shimelis Hailemeskel ◽  
...  

Background: More than one third of the neonatal deaths at Neonatal Intensive Care Unit of Debre Tabor General Hos- pital (DTGH) are attributable to birth asphyxia. Most of these neonates are referred from maternity ward of the hospital. However, there is no recent evidence on the prevalence and specific determinants of birth asphyxia at DTGH. Besides, public health importance of factors like birth spacing weren’t addressed in the prior studies. Methods: A cross sectional study was conducted on a sample of 240 newborns at delivery ward. The collected data were cleaned, coded and entered into Epi -data version 4.2 and exported to Stata version 14. Binary logistic regression model was considered and statistical significance was declared at P< 0.05 using adjusted odds ratio. Results: The prevalence of asphyxia neonatorum was 6.7 % based on the fifth minute APGAR score. From multi-variable logistic regression analysis, antenatal obstetric complications (AOR = 2.63, 95% CI: 3.75, 14.29), fetal malpresentation (AOR = 3.17, 95% CI: 1.21, 15.20), premature rupture of fetal membranes (AOR = 6.56, 95% CI: 3.48, 18.12) and meconium stained amniotic fluid (AOR = 2.73, 95% CI: 1.76, 14.59) were significant predictors. Conclusion: The prevalence of fifth minute asphyxia neonatorum was relatively low. Fortunately, its predictors are modifi- able. Thus, we can mitigate the problem even with our limited resources such as enhancing the existing efforts of antenatal and intra-partum care, which could help early detection and management of any obstetric and neonatal health abnormality.” Keywords: Birth asphyxia; asphyxia neonatorum; prevalence; determinants; Ethiopia.

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Bedilu Kifle ◽  
Kifle Woldemichael ◽  
Mamo Nigatu

Background. Though onchocerciasis control and elimination through community directed treatment with ivermectin were conducted for the last fifteen years, prevalence of onchocerciasis and factors associated with it in the study area are yet not known. The aim of the current study is to assess prevalence of onchocerciasis and associated factors among adults aged greater than or equal to fifteen years in Semen Bench district, Bench Maji zone, southwest Ethiopia: community based cross-sectional study 2018. Methods. Community based cross-sectional study was conducted on 553 study participants selected by multistage sampling in April 2018. Data were collected using a pretested interviewer-administered questionnaire. Data were entered using EpiData version 3.1 and exported to SPSS version 20 for statistical analysis. Descriptive statistics were done to summarize dependent and independent variables. Bivariate logistic regression was done to select candidate variables. Multivariable logistic regression was performed to identify independent predictors of onchocerciasis infection. Adjusted odds ratios with 95% CI were calculated to assess association and statistical significance, respectively. Confidence interval was used to declare statistical significance. Result. The overall prevalence of onchocerciasis infection in the study area was 6.32%. Age category of 35-44 years (AOR: 13.48, 95%CI: 3.51, 51.76), age of 45 years and above (AOR: 9.41, 95% CI: 2.26, 39.06), male sex (AOR 4.568, 95% C.I: 1.622, 12.861), not being compliant with ivermectin treatment (AOR: 3.804, 95%CI: 1.524, 9.49), and residing at less than 2Km from the river (AOR: 9.15, 95%CI: 3.9, 21.49) were significantly associated with onchocerciasis infection. Conclusion and Recommendation. After more than a decade of treatment with ivermectin, onchocerciasis in the study area is still hypoendemic. Zonal health department and other stakeholders should evaluate therapeutic coverage and community directed treatment with ivermectin in the study area. Zonal health department with other stokeholds should give community based information education communication, giving due attention to older ages, male residents, and those living near the rivers. Further community based study should also be done to identify factors hindering the community compliance with the treatment.


2020 ◽  
Author(s):  
Amare Simegn Ayele ◽  
Demeke Mesfin Belay ◽  
Biniam Minuye Birihane

Abstract Background: Though, childbearing intention is normal, it is imperative in Human Immune Virus positive women and identifying their intention has significant in reducing mother to child transmission. This study was intended to assess childbearing intention and associated factors among women on antiretroviral therapy in South Gondar Hospitals, Northwest Ethiopia.Methods: Institution based cross sectional study was employed. The sample for each Hospitals was allocated proportionally. Systematic random sampling method was used to select the study participants. Data were coded and entered into epidata 4.2 software and exported to statistical package for social sciences version 25 for analysis. Binary logistic regression was used to saw the association between each independent variable and dependent variable. All variables with P-value < 0.25 during bi-variable analyses were considered for multivariable logistic regression analyses. Odds ratio along with 95%CI were estimated to measure the strength of the association. Level of statistical significance was declared at p value less or equal to 0.05.Results: - A total of 418 women on antiretroviral therapy participated in the study. Child bearing intention was 42.6%. History of pregnancy after HIV diagnosis [Adjusted Odd Ratio (AOR) =5.19, 95% CI: (1.83, 14.7)], Partners fertility desire [AOR=10.99, 95% CI: (4.34, 27.86)], having alive children [AOR=0.23, 95% CI: 0.23(0.81, 0.63)] were significantly associated with childbearing intention.Conclusion. Childbearing intention of women on antiretroviral treatment was low. Having partner’s fertility desire, had pregnancy after HIV diagnosis and have alive child were significantly associated with childbearing intention. Information needs to be shared for the clients by using counseling protocols developed to achieve their desired reproductive goals.


2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Dawit Kumilachew Yimenu ◽  
Fitsum Sebsibe Teni ◽  
Awol Jemal Ebrahim

Background. Unused medicines are those that are expired, discontinued, deteriorated, and/or not intended for any future use. The aim of this study was to assess the prevalence of unused medicines and predicting factors in households of Awi zone, Amhara regional state, Northwestern Ethiopia. Methods. A community-based cross-sectional study was conducted. A survey of unused medicines was conducted through interviews with representatives of households. The collected data were entered with Epi Data version 3.1 and exported to SPSS version 21 for analysis. Predictors of storage of unused medicines were assessed through binary and multivariable logistic regression methods. A confidence interval of 95% and a P-value of <0.05 were considered to declare statistical significance. Results. Of the total of 507 households surveyed, 70 (13.8%) were found to have unused medicines. These constituted twenty-eight types of unused medicines. Anti-infective medicines were the most commonly unused medicines, 58.9%. People who pay for medicines by themselves, those who lacked knowledge about medicines, and those who did not receive enough counseling about medicines they took were found to be 2.6, 4.8, and 3 times more likely to have unused medicines, respectively. Conclusion. A significant amount of unused medicines was present in the community. Strategies aimed at educating the public regarding the safe disposal of unused medicines and an organized method of collection and disposal of unused medicines in the community need to be introduced.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Tesfaye Derseh ◽  
Tariku Dingeta ◽  
Mohammed Yusouf ◽  
Binyam Minuye

Background. Despite the advancement in the healthcare system, the impact of surgical interventions on public health systems will continue to grow. But predicting the outcome is challenging. Concerns related to unexpected outcomes and delays in the diagnosis of postoperative complications are the major issue. Intestinal obstruction is a common life-threatening surgical condition followed by fatal and nonfatal postoperative complications. This study was aimed at assessing results after surgery for intestinal obstruction in a hospital of Ethiopia. Methodology. An institutional-based cross-sectional study was conducted among 254 postoperative patients admitted with intestinal obstruction from January 1, 2014, to December 31, 2017. Data were coded and entered into EpiData 4.2.0.0 software and exported to the Statistical Package for the Social Sciences version 22 for analysis. A binary logistic regression model was used for analysis. All variables with a p value < 0.25 during bivariable analysis were considered for multivariable logistic regression analysis. Results. The magnitude of poor surgical outcome of intestinal obstruction was 21.3% for patients enrolled into this investigation. The age group of ≥55 years ( adjusted   odds   ratio   AOR = 2.9 , 95% CI: 1.03, 8.4), duration of illness of ≥24 hrs ( AOR = 3.1 , 95% CI: 1.03, 9.4), preoperative diagnosis of a gangrenous large bowel ( AOR = 3.6 , 95% CI: 1.3, 9.8), and a gangrenous small bowel ( AOR = 4.2 , 95% CI: 1.3, 13.7) were significantly associated with poor surgical outcome. Conclusions. The magnitude of poor surgical outcome was high. Age, late presentation of illness, and gangrenous bowel obstructions were significantly associated with poor outcomes. So, concern should be given in early detection and follow-up of patients who came late and older patients.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Gebrehiwot Teklehaimanot Gebregziabher ◽  
Fikaden Berhe Hadgu ◽  
Haftom Temesgen Abebe

Background. Perinatal asphyxia is defined as the inability of the newborn to initiate and sustain enough respiration after delivery and is characterized by a marked impairment of gas exchange. It is one of the most common causes of neonatal mortality and morbidity. There are very few studies on perinatal asphyxia in Tigray, and so this study is aimed at assessing the prevalence and associated factors of perinatal asphyxia in Ayder Comprehensive Specialized Hospital NICU, Tigray, Ethiopia. Methods. An institution-based cross-sectional study design was conducted among neonates admitted to Ayder Comprehensive Specialized Hospital from January 1, 2016, to December 30, 2017. Medical records of 267 neonates admitted to the neonatal intensive care unit were selected by a systematic sampling method, and relevant information was collected using a checklist. The data was analyzed using SPSS version 20. Descriptive statistics were computed to determine the prevalence of birth asphyxia and sociodemographic and obstetrics data. Binary logistic regression was used to test associations between the associated factors and perinatal asphyxia. First bivariate analysis was performed to assess the association without controlling the effect of other independent variables. Variables with P value < 0.25 were fitted to the multivariable binary logistic regression model. Finally, variables with P value < 0.05 were expressed as associated factors of perinatal asphyxia. Results. Of the 267 neonates, 48 neonates had perinatal asphyxia, giving a prevalence of 18%. Prolonged labor (AOR=5.19, 95% CI: 1.73-15.63, P=0.003), presence of meconium (AOR=4.17, 95% CI: 1.34-12.98, P=0.014), and preeclampsia (AOR=7.94, 95% CI: 2.22-28.37, P=0.001) were important determinant factors for birth asphyxia. The case fatality rate of perinatal asphyxia was 37.5%. Conclusion and Recommendations. Prevalence and mortality of asphyxia were high. Prolonged labor, presence of meconium, and preeclampsia were determinant factors for birth asphyxia. Early detection and intervention of high-risk mothers should be carried out by health care providers, and mothers should be monitored with partograph during labor.


2020 ◽  
Author(s):  
Alemu Degu Ayele ◽  
Fentahun Yenealem Beyene ◽  
Bekalu Getnet Kassa ◽  
Gedefaye Nibret Mihretie

Abstract Background: - Even though vasectomy is one of the safest, simple and most effective family planning methods available for men, it is one of the least used contraceptive methods in developing world including Ethiopia. The main reason for low level use may be low knowledge about vasectomy among men. This study was therefore designed to assess knowledge of vasectomy and its associated factors among married men in Debre Tabor Town.Methods: - A community based cross-sectional study was conducted among 418 married men from December 05 - 25, 2019. Simple random sampling technique was employed. Data was collected by face to face interview using structured and pre-tested questionnaire. Data was entered using Epi- Data version 4.2 and analyzed by SPSS version 23. The association between variables was analyzed using bivariable and multivariable logistic regression model. Finally variables having p-value < 0.05 at 95% CI were considered as statistically significant. Results: A total of 418 participants were included with response rate of 98.8%. The mean age of participant was 38.06 (SD± 6.873) years. About 60.5% of men had ever heard about vasectomy. Men mentioned health care providers as main source of information. Among those who had ever heard, only 58.8% defined vasectomy correctly. About 25.6% equated vasectomy with castration and about 15.6% described as “it is making the man impotent. In this study, only 38.5% of men were knowledgeable about vasectomy. Multivariable logistic regression showed that completing secondary education (AOR= 4.70, 95% CI: 1.26--17.55), attending college and above (AOR=8.36, 95% CI: 2.41-28.97)), having 4 or more alive children (AOR=0.51, 95% CI: 0.29-0.89) and positive attitude (AOR= 2.47, 95% CI: 1.58-3.86) were significantly associated with knowledge of vasectomy. Conclusions: In this study level of knowledge of married men about vasectomy was low. Educational status, number of children and attitude were statistically significant with men knowledge about vasectomy. Emphasis should be given on improving the educational status of men to improve their knowledge, and positively changing the men upbringing culture right from their childhood which will also improve their attitude towards vasectomy in the future.


2020 ◽  
Vol 17 (1) ◽  
pp. 82-93
Author(s):  
Mary-Joe Youssef ◽  
Antoine Aoun ◽  
Aline Issa ◽  
Lana El-Osta ◽  
Nada El-Osta ◽  
...  

Background: The prevalence of gastroesophageal reflux disease (GERD) is increasing worldwide and the related chronic symptoms can be associated with morbidity and poor quality of life. Objective: The objective of this study was to identify foods and beverages consumed by the Lebanese population, dietary habits, socio-demographic and lifestyle factors, health parameters and perceived stress, implicated in increasing GERD symptoms. Methods: This observational cross-sectional study was carried among Lebanese adults in 2016. A convenient sample of 264 participants was equally divided into a GERD group and a control group. Data on socio-demographic characteristics, lifestyle, health status and dietary habits including Lebanese traditional dishes were collected. The perceived stress scale (PSS) was also used to assess the participants’ perception of stress. Logistic regression analyses were conducted with GERD symptoms (presence or absence) being the dependent variable. Results: The GERD symptoms were significantly associated with age (-p-value=0.017), family history of GERD symptoms (-p-value<0.001), smoking (-p-value=0.003) and chronic medical conditions (-p-value<.001). Regarding the dietary factors, participants who ate three meals or less/day, between meals and outside homes were 2.5, 2.9 and 2.4 times at a higher risk of experiencing GERD symptoms than others, respectively. Moreover, the logistic regression model showed that the GERD symptoms were significantly associated with the consumption of coffee (-p-value=0.037), Lebanese sweets (-p-value=0.027), fried foods (-p-value=0.031), ‘Labneh’ with garlic (-p-value<0.001), pomegranate molasses (-p-value=0.011), and tomatoes (-p-value=0.007). Conclusion: Some specific lifestyle factors and components of the Lebanese Mediterranean diet could be associated with GERD symptoms.


BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e051821
Author(s):  
Lisa Bero ◽  
Rosa Lawrence ◽  
Louis Leslie ◽  
Kellia Chiu ◽  
Sally McDonald ◽  
...  

ObjectiveTo compare results reporting and the presence of spin in COVID-19 study preprints with their finalised journal publications.DesignCross-sectional study.SettingInternational medical literature.ParticipantsPreprints and final journal publications of 67 interventional and observational studies of COVID-19 treatment or prevention from the Cochrane COVID-19 Study Register published between 1 March 2020 and 30 October 2020.Main outcome measuresStudy characteristics and discrepancies in (1) results reporting (number of outcomes, outcome descriptor, measure, metric, assessment time point, data reported, reported statistical significance of result, type of statistical analysis, subgroup analyses (if any), whether outcome was identified as primary or secondary) and (2) spin (reporting practices that distort the interpretation of results so they are viewed more favourably).ResultsOf 67 included studies, 23 (34%) had no discrepancies in results reporting between preprints and journal publications. Fifteen (22%) studies had at least one outcome that was included in the journal publication, but not the preprint; eight (12%) had at least one outcome that was reported in the preprint only. For outcomes that were reported in both preprints and journals, common discrepancies were differences in numerical values and statistical significance, additional statistical tests and subgroup analyses and longer follow-up times for outcome assessment in journal publications.At least one instance of spin occurred in both preprints and journals in 23/67 (34%) studies, the preprint only in 5 (7%), and the journal publications only in 2 (3%). Spin was removed between the preprint and journal publication in 5/67 (7%) studies; but added in 1/67 (1%) study.ConclusionsThe COVID-19 preprints and their subsequent journal publications were largely similar in reporting of study characteristics, outcomes and spin. All COVID-19 studies published as preprints and journal publications should be critically evaluated for discrepancies and spin.


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