scholarly journals Comparative Investigation on the Concentrations of Dehydroepiandrosterone (DHEA) and Testosterone Levels in Infertile Males attending a Private University Teaching Hospital, in Rivers State, Nigeria

2021 ◽  
Vol 25 (8) ◽  
pp. 1465-1469
Author(s):  
I.M. George-Opuda ◽  
A.O. Adegoke ◽  
O.E. Bamigbowu ◽  
C. Nwaganga

The study was carried out to determine the concentrations of Dehydroepiandrosterone hormone (DHEAS) and testosterone in infertile males and compared with fertile males attending Madonna University Teaching Hospital (MUTH) Elele. Thirty apparently infertile males and 30 apparently fertile male as control had their Dehydroepiandrosterone hormone (DHEAS) and testosterone determined using competitive immune enzymatic colorimetric method and Enzyme Immunoassay while the semen analysis was done using Microscopy method. There was significant increase (P<0.05) in DHEAS of 1.23+0.07 ug/ml obtained in infertile male compared with 3.78 +0.13 ug/ml in the control. There was significant difference in Semen count of 56.27 +2.82million/ml in fertile males compared with 7.73+ 0.10 million/ml while testosterone in infertile males of 2.53+0.09 was significantly lower than 7.52+0.31 in fertile males(P<0.05). The study showed that DHEAS is elevated in infertility hence should be considered an indicator of infertility.

Author(s):  
Boma Awoala West ◽  
Adaku Arthur ◽  
Josephine Enekole Aitafo ◽  
Hannah Omunakwe

Aim: There is paucity of literature on the prevalence of neonatal anaemia globally thus aim of the study was to evaluate the prevalence, determine the associations and the clinical outcome of neonates with anaemia. Study Design: This was a descriptive prospective cross-sectional study. Place and Duration of Study: Study was carried out among neonates admitted in the Special Care Baby Unit of Rivers State University Teaching Hospital over one year. Methodology: A convenient sampling size of 402 neonates who met the inclusion criteria were consecutively recruited. Data was analysed using SPSS version 23. Results: Of 402 neonates assessed, 106(26.4%) had anaemia with PCV less than 42%.   Anaemia was observed more in males 56(52.8%), neonates delivered via Caesarean section 74(69.8%) and at gestational age less than 37 weeks 53(50%). Mild anaemia was observed mostly, 66(62.3%). Common pregnancy complications of mothers with anaemic babies were prolonged rupture of membranes 17(35.4%) and hypertension in pregnancy 14(29.2%) while the commonest morbidities in these neonates were probable sepsis 65(63.8%), neonatal jaundice 53(52%) and prematurity 53(52%). There was significant difference in anaemic and non-anaemic neonates with regards to mothers with gestational diabetes (P value < 0.0001). The factors associated with severe anaemia were probable sepsis and the duration of stay. Blood transfusion was carried out in 27(25.5%) neonates. An overall mortality of 7.5% was documented, severe anaemia being highest (21.4%). Conclusion: The prevalence of anaemia was high being 26.4% and was observed more in males, preterms and babies delivered via Caesarean section. There was significant difference in anaemic and non-anaemic neonates with regards to mothers with gestational diabetes. Probable sepsis and duration of stay were significantly associated with severe anaemia. The mortality rate in neonates with anaemia was 7.5% thus there is need to assess newborns for anaemia with prompt intervention to prevent morbidity, mortality and long term sequelae.


Author(s):  
P. A. Awoyesuku ◽  
D. A. Macpepple ◽  
B. O. Altraide ◽  
D. H. John

Background: Infection with hepatitis B (HBV) and human immunodeficiency virus (HIV) are global public health problems. These infections during pregnancy increase the risk of maternal morbidity and mortality, and also pose a risk to the fetus due to mother to child transmission. Objective: To determine the prevalence of seropositive HIV and HBsAg cases amongst pregnant women at the Rivers State University Teaching Hospital (RSUTH). Methodology: A retrospective review of hospital and laboratory records of all pregnant women booked at RSUTH in two years, from May 2017 to April 2019, was carried out. Data on patients’ age, parity and educational level and reactivity of HIV and HBsAg test at booking were retrieved using structured proforma and analyzed using Epi Info Version 7. Test for significance using Chi-square was set at a significant level of P<0.05. Results: 3560 patients had HIV and HBsAg screening out of which 148 (4.2%) and 9 (0.3%) respectively were positive. The comorbidity rate in this study was 0.06%. The mean age was 31.5±4.7 years and the mean gestational age at booking was 22.1±6.8 weeks. There was no significant relationship between their age (χ2 = 2.690, p-value=0.442) and parity (χ2 = 3.759, p-value = 0.145) with HIV seropositivity, but these were significant for HBsAg (χ2 = 13.691, p-value = 0.003) (χ2 = 13.121, p-value=0.001).  Educational status was significant for HIV (χ2 = 16.188, p-value=0.000) but not for HBsAg (χ2 = 0.229, p-value=0.892). Conclusion: The seroprevalence rate of HIV and HBsAg in this study were low. HIV seroprevalence was significantly affected by lower education, while HBsAg seroprevalence was significantly affected by younger maternal age and nulliparity. Continued screening of pregnant women for these infections remains valuable and further community-based studies to identify risk factors are recommended.


Author(s):  
S. Eli ◽  
D. G. B. Kalio ◽  
K. E. Okagua ◽  
A. A. Aloku ◽  
B. O. A. Atraide ◽  
...  

Background: The prevalence of diabetes mellitus (DM) have tripled from 1980 till date as a result of many factors of which obesity/excessive weight gain is a closely related factor of DM. There are many adverse challenges of DM in pregnancy with its associated fetal and maternal consequences. Aim: To determine the prevalence of DM in pregnancy amongst antenatal clinic (ANC) at booking at the Rivers State University Teaching Hospital (RSUTH). Methods: It was a cross sectional study of ANC attendees at booking at the RSUTH. Simple random sampling method was used. The Information was coded and analyzed using SPSS version 25. Results: A total of 99 pregnant women were recruited at booking in the ANC of the RSUTH. The mean age was 32.2 years and the modal parity was 1.0.The number of ANC attendees with weight equal to or greater than 90 Kg were 21 (21.2%), number with weight greater than equal to 90 Kg with glucose in urine were 10 (10.1%) Three (3.0%) of the subjects were known diabetic whereas 12 (12.1%) had family history of DM. Conclusion: The study revealed the prevalence of DM amongst ANC attendees at the RSUTH as 3.0%. There was corresponding glycosuria in 10.1% of the ANC attendees. ANC attendees had family history of DM were 12.1%. Advocacy is needed to educate the populace on the predisposing factors of DM and its adverse effect on maternal and child health.


Author(s):  
P. A. Awoyesuku ◽  
D. A. MacPepple ◽  
N. J. Kwosah

Background: Untreated maternal syphilis is strongly associated with adverse birth outcomes. The WHO recommends routine serological screening in pregnancy. Some workers have advised a reappraisal of this practice, having demonstrated low seroprevalence in their antenatal population. Objective: To determine the prevalence of seropositive VDRL cases amongst pregnant women at the Rivers State University Teaching Hospital (RSUTH) in order to justify the need and cost-effectiveness for continued routine syphilis screening using VDRL alone. Methodology: A retrospective review of hospital and laboratory records of all pregnant women booked for antenatal care (ANC) at RSUTH in a two-year period, from May 2017 to April 2019, was carried out. Data on patients’ age, parity and educational level, and reactivity of VDRL test at booking were retrieved using structured pro-forma and analyzed using Epi Info Version 7. Test for significance using Chi-square was set at significant level of P<0.05. Results: 3560 clinic patients had VDRL screening out of which 63 were positive. The overall prevalence rate in this study was 1.8%. The mean age was 31.5±4.7 years and the mean gestational age at booking was 22.1±6.8 weeks. There was no significant relationship between their age (χ2 = 0.403, p-value=0.940), parity (χ2 = 3.707, p-value=0.0.157), and educational status (χ2 = 1.853, p-value=0.396), and seropositivity. The cost of VDRL test per patient in RSUTH is $3, to detect the 63 cases the sum of $10,680 was spent. Conclusion: The seroprevalence rate of syphilis in this study was low. Initial screening using VDRL alone is neither justified nor cost effective. Selective screening based on risk factors and specific test with TPHA is recommended.


Author(s):  
Peter A. Awoyesuku ◽  
Dickson H. John ◽  
Dickson H. John ◽  
Lewis B. Lebara ◽  
Lewis B. Lebara

Background: Severe preeclampsia and eclampsia remain a challenge in tropical obstetric practice. It is a major contributor to feto-maternal morbidity and mortality in developing countries. This study seeks to determine the prevalence, associated risk factors and the feto-maternal outcome of severe preeclampsia and eclampsia at the rivers state university teaching hospital (RSUTH).Method: A retrospective study of all women who had severe preeclampsia and eclampsia and were delivered at the RSUTH in a two-year period, 1ST January 2018 to 31ST December 2019, was carried out. Data on patients’ age, parity, education, booking status, gestational age at delivery, diagnosis, complications, mode of delivery and fetal sex, birth weight and Apgar scores were retrieved using structured pro-forma. Data were analyzed using SPSS version 20.Results: There were 4496 deliveries of which 128 had severe preeclampsia and eclampsia, giving a prevalence of 2.85%. Of these, 94 (73.4%) had severe preeclampsia and 34 (26.6%) had eclampsia. The mean age of the women ± SD was 29.84±5.44 years, median parity was para 1, and mean gestational age ± SD was 35.38±3.84 weeks. There were 10 maternal deaths giving case fatality of 7.8%. The mean birth weight ± SD was 2.61±0.91 kg and stillborn rate was 14.4%. There was significant association with maternal age, education, booking status, method of delivery and Apgar score of the baby.Conclusion: The prevalence in this study is high with associated high maternal mortality and stillborn rates. Timely and appropriate intervention including primary management and judicious termination of pregnancy will reduce mortality of mother and fetus.


2021 ◽  
Vol 10 (1) ◽  
pp. 218-223
Author(s):  
Kalio DGB ◽  
Eli S ◽  
Okagua KE ◽  
Allagoa DO

Background: Post-operative anaemia is often a reflection of pre-operative pre-operative work-up and pre-operative anaemia. In addition. Post-operative anaemia is also determined by co-morbidities of patients prior to surgery. The prevalence of post-operative anaemia varies based on surgical specialties and the experience of the surgeon; prevalence rates as high as 85% have been recorded in orthopaedic surgeries. Aim: To determine the prevalence of post-operative anaemic in surgical patients at the Rivers State University Teaching Hospital (RSUTH). Method: This was a six months cross sectional study of the post-operative anaemia of patients who had operation at the Surgery and Obstetrics/Gyaecology departments of The Rivers State University Teaching Hospital. The permission for the study was granted by the head of department of obstetrics and gynaecology in conjunction with the head of .the hospital management. The yard stick for anaemia was packed cell volume less than 33% in line with the World Health Organization (WHO). A structured proforma was used to obtain information from patient’s case notes and analyzed using SPSS version 25. Result: Three hundred and eigthy subjects were recruited for the study. Males subjects were 150 (39.5%) while females were 230 (60.5%) respectively. The mean age was 31 years. One hundred and ninety nine (52.4%) were obstetrics and gynaecological surgeries while 181 (47.6 %) were non-gynaecological surgeries. The commonest indication for surgery was caesarean section representing 130 (34.2%) of the subjects. Two hundred and sixty six of the subjects (70%) had PCV less than 33%. One hundred and fifty two (40%) women had PCV less than 33% while 114 (30%) of the men had PCV less than 33%. Conclusion: The study revealed that prevalence of post-operative anaemia amongst surgical patients at RSUTH was 70 %. The post-operative anaemia amongst women was worrisome. The need to optimize patients prior to surgery cannot be over-emphasized to prevent morbidities and mortalities post-operative.


2014 ◽  
Vol 16 (2) ◽  
pp. 71
Author(s):  
AjenS Anzaku ◽  
OlarenwajuO Makinde ◽  
Samaila Mikah ◽  
StevenN Shephard

2019 ◽  
Vol 2 (2) ◽  
pp. 113-120
Author(s):  
DI Attah ◽  
S Ochejele ◽  
MC Attah ◽  
M Ochoga

Cervical carcinoma is a preventable disease yet it remains the leading genital malignancy among women in sub-Saharan Africa. The study objective was to compare the knowledge, attitude and acceptance of cervical cancer screening among female health Personnel and non- health Personnel in Jos University Teaching Hospital (JUTH). JUTH. This was a across-sectional study conducted in JUTH between 15th June and 31st July, 2008. There was significant difference in knowledge between the health personnel 288(91.4%) and non-health personnel 145(36.2%) p value < 0.01. Most (73.7%) of the health personnel had correct knowledge about pap smear as a screening procedure for cervical cancer. Doctors had the highest correct knowledge of 97.5%. Only 64(16.0%) of the non-health personnel had correct knowledge about pap smear. Teachers and those attending Gynaecological clinics had the highest correct knowledge of 45.0% and 24.0% respectively. There was significant difference in the overall rate of screening between the health personnel 75(23.8%) and the non-health personnel 44(11.0%). Out of the respondents that had knowledge about pap smear 42(29.0%) of the 145 non-health personnel and 75(26.0%) of the 288 health personnel had screened with no significant difference between the two groups. The two groups had similar reasons why those that were yet to screen had not screened. About 81.3 % of the health personnel and 87.1% of non-health personnel who were yet to screen would like to be screened. There is the need to carefully draw up a plan to tackle the poor knowledge, attitude and acceptance of cervical cancer and its prevention among our women.


Author(s):  
P. A. Awoyesuku ◽  
B. O. A. Altraide

Background: Effective contraception can prevent unwanted pregnancy, unsafe abortion and ensure adequate birth spacing. The choice of a method depends on consideration of its advantages and disadvantages based on individual perception and interpretations. Objective: To assess contraceptive choices and acceptability among new clients at the family planning clinic of a tertiary health facility in Rivers State, Nigeria. Methodology: This was a one-year retrospective review of clinical records of new clients attending the Family Planning Unit of the Rivers State University Teaching Hospital from January 1, to December 31, 2018. Data on age, education, marital status, parity, contraceptive choice and reason for contraception were retrieved and analyzed using Epi-Info version 7.1.4. Results:  A total of 124 female clients were enrolled during the time period. The mean age of the participants was 33.8±5.1 years and the median parity was 3. The most common method of contraception accepted by the clients was implants 87 (70.2%), followed by intrauterine device 32 (25.8%), then injectable 4 (3.2%) and oral contraceptive pills 1(0.8%). Reasons proffered for use of contraceptive was mainly completed family size 69 (55.6%), pregnancy prevention 53 (42.8%) and child spacing 2 (1.6%). There was no significant difference on comparism of mean age and median parity of clients by choice of contraceptive method. Conclusion: The implant methods were the most commonly accepted, while the oral contraceptive pill was the least preferred. Completed family size was the most common reason for contraception.


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