scholarly journals Efectos de la radiación electromagnética: Un estudio de caso

2021 ◽  
Vol 2 (5) ◽  
pp. 7040-7052
Author(s):  
Paula Andrea Benito Benito ◽  
Manuel Yecid Fernandez Torres ◽  
Jhonny Orlando Tolosa Cetina
Keyword(s):  
Human Health ◽  
Qualitative Methodology ◽  
Prolonged Exposure ◽  
Biological Effects ◽  
Physical Phenomenon ◽  
The Subject ◽  
Points Of View ◽  
Electromagnetic Radiations ◽  
Rule Out

En este trabajo se analizan los efectos biológicos de las radiaciones electromagnéticas a partir de la recopilación y comparación de fuentes bibliográficas que evidencian el estudio de dicho fenómeno físico, analizado mediante una metodología cualitativa basada en la revisión bibliográfica de trabajos que reportan aspectos fundamentales del tema en cuestión y examinados por medio de una matriz de análisis que recoge los puntos de vista más importantes de cada investigación. Dentro de los resultados obtenidos no hay coincidencia, ya que algunos autores apoyan la idea de que estas radiaciones son perjudiciales para la salud humana, mientras que otros no descartan la posibilidad de que estas puedan ser inofensivas para el ser humano, pero sin desechar el riesgo de que a largo plazo puedan generar problemas de salud. Después de realizar las evaluaciones correspondientes y utilizar los métodos ya mencionados con anterioridad, se concluye que las radiaciones electromagnéticas pueden llegar a ser perjudiciales para la salud humana a exposiciones prolongadas, por esto se advierte sobre posibles enfermedades y se dan recomendaciones al respecto.   This work analyzes the biological effects of electromagnetic radiation based on the compilation and comparison of bibliographic sources that evidence the study of this physical phenomenon, analyzed by means of a qualitative methodology based on the bibliographic review of works that report fundamental aspects of the subject in question and examined by means of an analysis matrix that gathers the most important points of view of each research. Within the results obtained there is no coincidence, since some authors support the idea that these radiations are harmful to human health, while others do not rule out the possibility that they may be harmless to humans, but without discarding the risk that in the long term they may generate health problems. After performing the corresponding evaluations and using the methods mentioned above, it is concluded that electromagnetic radiations may be harmful to human health with prolonged exposure, and for this reason a warning is given about possible diseases and recommendations are given in this regard.

scholarly journals Plant Polyphenols as Dietary Antioxidants in Human Health and Disease

2009 ◽  
Vol 2 (5) ◽  
pp. 270-278 ◽  
Author(s):  
Kanti Bhooshan Pandey ◽  
Syed Ibrahim Rizvi
Keyword(s):  
Cardiovascular Diseases ◽  
Human Health ◽  
Biological Effects ◽  
Epidemiological Studies ◽  
Present Knowledge ◽  
Plant Polyphenols ◽  
Potential Health ◽  
Health And Disease ◽  
Meta Analyses

Polyphenols are secondary metabolites of plants and are generally involved in defense against ultraviolet radiation or aggression by pathogens. In the last decade, there has been much interest in the potential health benefits of dietary plant polyphenols as antioxidant. Epidemiological studies and associated meta-analyses strongly suggest that long term consumption of diets rich in plant polyphenols offer protection against development of cancers, cardiovascular diseases, diabetes, osteoporosis and neurodegenerative diseases. Here we present knowledge about the biological effects of plant polyphenols in the context of relevance to human health.

scholarly journals Glucosamine for Osteoarthritis: Biological Effects, Clinical Efficacy, and Safety on Glucose Metabolism

Arthritis ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Juan Salazar ◽  
Luis Bello ◽  
Mervin Chávez ◽  
Roberto Añez ◽  
Joselyn Rojas ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Biological Effects ◽  
The Elderly ◽  
Long Term Effects ◽  
Management Schemes ◽  
Mechanical Factors ◽  
The Subject ◽  
Degenerative Disorder ◽  
Methodological Aspects

Osteoarthritis is a chronic degenerative disorder that currently represents one of the main causes of disability within the elderly population and an important presenting complaint overall. The pathophysiologic basis of osteoarthritis entails a complex group of interactions among biochemical and mechanical factors that have been better characterized in light of a recent spike in research on the subject. This has led to an ongoing search for ideal therapeutic management schemes for these patients, where glucosamine is one of the most frequently used alternatives worldwide due to their chondroprotective properties and their long-term effects. Its use in the treatment of osteoarthritis is well established; yet despite being considered effective by many research groups, controversy surrounds their true effectiveness. This situation stems from several methodological aspects which hinder appropriate data analysis and comparison in this context, particularly regarding objectives and target variables. Similar difficulties surround the assessment of the potential ability of glucosamine formulations to alter glucose metabolism. Nevertheless, evidence supporting diabetogenesis by glucosamine remains scarce in humans, and to date, this association should be considered only a theoretical possibility.

Analysis and assessment of forensic medical examinations and studies of living individuals who have experienced acute intestinal infections for 2018–2019 according to the BSME of the subject of the Russian Federation

2020 ◽  
Author(s):  
Olga Gritskevich ◽  
Dmitriy Kadochnikov
Keyword(s):  
Human Health ◽  
Medical Examination ◽  
Modern Approach ◽  
Intestinal Infections ◽  
The Subject ◽  
The Russian Federation ◽  
Medical Examinations ◽  
Main Factor

To assess the modern approach in determining the severity of harm to human health in acute intestinal infections, an analysis of the acts of the forensic medical examination of living persons who have suffered acute intestinal infections was carried out on the basis of the forensic medical examination bureau of the southern region for 2018–2019. The analysis showed that today, children are more susceptible to acute intestinal infections, and according to the standards for assessing the degree of harm to human health, the main factor is taken into account, the number of days spent on inpatient or outpatient treatment, regardless of the severity of the infection. In this case, no attention is paid to the long-term consequences of the infection, which, in turn, lead to chronic diseases of the gastrointestinal tract and significantly reduce the quality of life. The findings indicate the need to develop criteria for assessing the severity of harm to health in acute intestinal infections. This will make it possible to systematize the approach and objectively assess the degree of harm caused to health.

Stages and methods of legalization of criminal proceeds obtained as a result of economic and tax crimes

2020 ◽  
Vol 2020 (3) ◽  
pp. 148-156
Author(s):  
Pyotr Ivanov
Keyword(s):  
Law Enforcement ◽  
Money Laundering ◽  
Economic Security ◽  
Theory And Practice ◽  
Scientific Publications ◽  
The Subject ◽  
Points Of View ◽  
Internal Affairs

In this article, based on the study and analysis of operational-search legislation, scientific publications, law enforcement practice and the criminal situation in the field of legalization, the operationalsearch counteraction to the legalization of income received from the Commission of tax crimes is considered. The paper focuses on the stages (stages) of laundering, the existing points of view on this account, as well as on the methods of illegal withdrawal of funds abroad. The author of the article aimed to develop scientifically based proposals and recommendations for improving the effectiveness of this type of activity by the territorial bodies of internal Affairs and their divisions of economic security and anti-corruption. It is proposed to put forward and work out operational search versions within the subject of study, as well as to develop, taking into account the methods (schemes) used by criminals to launder criminal proceeds and illegally withdraw funds abroad for the purpose of their subsequent legalization, operational search measures to document their criminal actions. In addition, the author recommends constant monitoring of money laundering methods based on operational and investigative practices. The results and key conclusions formulated in this article can be used in the theory and practice of operational investigative activities of internal Affairs bodies to counteract the legalization of income received from tax crimes.

The mechanistic role of thymoquinone in Parkinson's disease: focus on neuroprotection in pre-clinical studies

2021 ◽  
Vol 14 ◽  
Author(s):  
Mohammad Najim Uddin ◽  
Mohammad Injamul Hoq ◽  
Israt Jahan ◽  
Shafayet Ahmed Siddiqui ◽  
Chayan Dhar Clinton ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Studies ◽  
Nigella Sativa ◽  
Biological Effects ◽  
Neuroprotective Activity ◽  
Substantia Nigra Pars Compacta ◽  
Movement Difficulties

: Thymoquinone (TQ) is one of the leading phytochemicals, which is abundantly found in Nigella sativa L. seeds. TQ exhibited various biological effects such as antioxidant, anti-inflammatory, antimicrobial, and anti-tumoral in several pre-clinical studies. Parkinson's disease (PD) is a long-term neurodegenerative disease with movement difficulties, and the common feature of neurodegeneration in PD patients is caused by dopaminergic neural damage in the substantia nigra pars compacta. The neuroprotective activity of TQ has been studied in various neurological disorders. TQ-mediated neuroprotection against PD yet to be reported in a single frame; therefore, this review is intended to narrate the potentiality of TQ in the therapy of PD. TQ has been shown to protect against neurotoxins via amelioration of neuroinflammation, oxidative stress, apoptosis, thereby protects neurodegeneration in PD models. TQ could be an emerging therapeutic intervention in PD management, but mechanistic studies have been remained to be investigated to clarify its neuroprotective role.

Conflicts caused by afforestations of agricultural land in densely populated areas

1991 ◽  
Vol 56 ◽  
Author(s):  
N. Lust ◽  
B. Muys
Keyword(s):  
Nature Conservation ◽  
Agricultural Land ◽  
Agricultural Lands ◽  
Biological Value ◽  
Ecological Problems ◽  
The Subject ◽  
Points Of View

In  densely populated areas, such as Flanders, serious conflicts arise due to the  afforestation of agricultural lands. Roughly speaking, three sectors are  involved: agriculture, forestry and nature conservation. These groups do not  always share the same points of view. But even within the different sectors  there are several subgroups with their own interests and approaches.  Generally speaking, agriculture is strongly opposed, forestry has a  relatively diversified meaning, whereas nature conservation is either opposed  or in favour, depending on the region's biological value.     The policy in this matter is not forest friendly. Legislation strongly  hampers the afforestation of agricultural lands. Moreover the subject leads  to a series of ecological problems, which have not really been considered up  to now.

scholarly journals Persistent, mobile and toxic (PMT) and very persistent and very mobile (vPvM) substances pose an equivalent level of concern to persistent, bioaccumulative and toxic (PBT) and very persistent and very bioaccumulative (vPvB) substances under REACH

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Sarah E. Hale ◽  
Hans Peter H. Arp ◽  
Ivo Schliebner ◽  
Michael Neumann
Keyword(s):  
Drinking Water ◽  
Human Health ◽  
Regulatory Decision ◽  
Drinking Water Resources ◽  
Trade Name ◽  
Chemicals Regulation ◽  
Range Transport ◽  
High Concern ◽  
Level Of Concern

Abstract Background Under the EU chemicals regulation REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals EC 1907/2006), registrants are not obliged to provide information related to intrinsic substance properties for substances that pose a threat to the drinking water resources. In 2019, perfluorobutane sulfonic acid (PFBS) and 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoic acid (HFPO-DA trade name GenX) were demonstrated to have an equivalent level of concern (ELoC) to persistent, bioaccumulative and toxic or very persistent and very bioaccumulative (PBT/vPvB) substances owing to their persistent, mobile and toxic (PMT) substance properties and very persistent and very mobile (vPvM) substance properties, respectively. They were both subsequently identified as substances of very high concern (SVHC) applying Article 57(f) in REACH. This work follows up on this regulatory decision by presenting a science based, conceptual level comparison that all PMT/vPvM substances pose an ELoC to PBT/vPvB substances. Using the two cases named above, as well as 1,4-dioxane, 16 categories were developed to evaluate a) serious effects on human health, b) serious effects on the environment and c) additional effects. 1,4-dioxane has recently been proposed to be classified as Carcinogenic 1B by the Committee for Risk Assessment (RAC). The aim was to enable an objective and scientifically justified conclusion that these classes of substances have an equivalent level of concern for the environment and human health. Results In all of the categories related to human health, the environment and other effects, the PMT/vPvM case study substances exhibited comparable effects to PBT/vPvB substances. A difference in the human and environmental exposure pathways of PMT/vPvM and PBT/vPvB substances exists as they vary temporally and spatially. However, effects and impacts are similar, with PMT/vPvM substances potentially accumulating in (semi-)closed drinking water cycles and pristine aquatic environments, and PBT/vPvB substances accumulating in humans and the food chain. Both PMT/vPvM and PBT/vPvB substances share the common difficulty that long term and long-range transport and risk of exposure is very difficult to determine in advance and with sufficient accuracy. Conclusion The registration process of substances under REACH should reflect that PMT/vPvM substances pose an equivalent level of concern to PBT/vPvB substances.

scholarly journals Impact of Prolonged Exposure of Eleven Years to Hot Seawater on the Degradation of a Thermoset Composite

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2154
Author(s):  
Amir Hussain Idrisi ◽  
Abdel-Hamid I. Mourad ◽  
Muhammad M. Sherif
Keyword(s):  
Exposure Time ◽  
Prolonged Exposure ◽  
Mechanical Performance ◽  
Matrix Cracking ◽  
Pull Out ◽  
Strength Based ◽  
Different Temperatures ◽  
River Line ◽  
Composite Samples

This paper presents a long-term experimental investigation of E-glass/epoxy composites’ durability exposed to seawater at different temperatures. The thermoset composite samples were exposed to 23 °C, 45 °C and 65 °C seawater for a prolonged exposure time of 11 years. The mechanical performance as a function of exposure time was evaluated and a strength-based technique was used to assess the durability of the composites. The experimental results revealed that the tensile strength of E-glass/epoxy composite was reduced by 8.2%, 29.7%, and 54.4% after immersion in seawater for 11 years at 23 °C, 45 °C, and 65 °C, respectively. The prolonged immersion in seawater resulted in the plasticization and swelling in the composite. This accelerated the rate of debonding between the fibers and matrix. The failure analysis was conducted to investigate the failure mode of the samples. SEM micrographs illustrated a correlation between the fiber/matrix debonding, potholing, fiber pull-out, river line marks and matrix cracking with deterioration in the tensile characteristics of the thermoset composite.

scholarly journals Myopericytoma in the Antitragus of the Auricle: A Rare Tumor

2020 ◽  
pp. 014556132098457
Author(s):  
Tae Seong Eo ◽  
Jeong Hae Kie ◽  
Hyun Seung Choi ◽  
Junhui Jeong
Keyword(s):  
Large Firm ◽  
Rare Tumor ◽  
Long Term Follow Up ◽  
Slow Growing ◽  
Rule Out

A myopericytoma in the auricle is rare. If an auricle contains a large, firm, red-brown mass, excision should be considered because the mass may be a myopericytoma. After excision, histopathological and immunohistochemical diagnoses are essential to rule out malignancy. Long-term follow-up is required because the tumor is slow-growing.

scholarly journals Onset and Resolution of Key Adverse Events in Valbenazine-Treated Patients with Tardive Dyskinesia: Pooled Analyses from Two Long-Term Clinical Trials

CNS Spectrums ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 151-151
Author(s):  
Stephen R. Marder ◽  
Jean-Pierre Lindenmayer ◽  
Chirag Shah ◽  
Tara Carmack ◽  
Angel S. Angelov ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Adverse Events ◽  
Tardive Dyskinesia ◽  
Suicidal Behavior ◽  
Prolonged Exposure ◽  
First Occurrence ◽  
Balance Disorder ◽  
Clinical Interest ◽  
Post Hoc

AbstractObjectiveTardive dyskinesia (TD) is a persistent and potentially disabling movement disorder associated with prolonged exposure to antipsychotics and other dopamine receptor blocking agents. Long-term safety of the approved TD medication, valbenazine, was demonstrated in 2 clinical trials (KINECT 3 [NCT02274558], KINECT 4 [NCT02405091]). Data from these trials were analyzed post hoc to evaluate the onset and resolution of adverse events (AEs).MethodsParticipants in KINECT 3 and KINECT 4 received up to 48 weeks of once-daily valbenazine (40 or 80 mg). Data from these studies were pooled and analyzed to assess the incidence, time to first occurrence, and resolution for the following AEs of potential clinical interest: akathisia, balance disorder, dizziness, parkinsonism, somnolence/sedation, suicidal behavior/ideation, and tremor.ResultsIn the pooled population (N=314), all AEs of potential clinical interest occurred in <10% of participants, with somnolence (9.6%), suicidal behavior/ideation (6.4%), and dizziness (5.7%) being the most common AEs. Mean time to first occurrence ranged from 36 days (akathisia [n=9]) to 224 days (parkinsonism [n=2]). By end of study (or last study visit), resolution of AEs was as follows: 100% (suicidal ideation/behavior, parkinsonism); >85% (somnolence/sedation, dizziness); >70% (akathisia, balance disorder, tremor).ConclusionsIn long-term clinical trials, the incidence of AEs of potential clinical interest was low (<10%) and most were resolved by end of treatment (>70–100%). All patients taking valbenazine should be routinely monitored for AEs, particularly those that may exacerbate the motor symptoms associated with TD.FundingNeurocrine Biosciences, Inc.

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