scholarly journals Precollagen Type III N-terminal Propeptide (PIIINP) a Biomarker Onset in Hypertensive Patients

2020 ◽  
Vol 1 (01) ◽  
pp. 25-28
Author(s):  
Hasanain Fadhil Mohammed ◽  
Sarah Hassan Jaber ◽  
Ali Jabbar Al-Zubaidi

The aim of this study is to asses PIIINP, lipid profile and BMI serum levels in patients with hypertension. The current research The results were Get it from the Draw Blood unity in Al-Sadder infirmary Teaching , Al-Najaf, Iraq, And AL HAKEEM General infirmary in AL-Najaf, Iraq, in 10 Dec 2018 – 19 Jan 2019. Age of hypertensive patients from 40 to Age 70 Normal blood pressure 40 to 70 years. The score show, serious increase (p<0.05) in PIIINP compared with control groups in patients with hypertension. For female patients, the findings of the reported substantially increased (p<0.05) for PIIINP relative to male patient groups. The findings showed a substantial increase (p<0.05) in PIIINP in age (60-70) relative to age (50-59) and (40-49) and increased substantially (p<0.05) in PIIINP in age (50-59) relative to age (40-49); The results showed significant differences in BMI between the hypertensive and the normotensive

1958 ◽  
Vol 36 (9) ◽  
pp. 889-893 ◽  
Author(s):  
P. Gaskell ◽  
A. M. Krisman

The brachial and digital blood pressures were estimated by auscultatory techniques in 10 patients with essential hypertension and in a group of 6 subjects with normal blood pressure who were in a state of regulated peripheral vasoconstriction and again when they were in a state of regulated vasodilatation. The brachial to digital systolic and diastolic pressure gradients in both control subjects and hypertensive patients were greater when the individuals were heated than when they were cooled. The brachial to digital diastolic pressure gradient in the hypertensive patients was not significantly different from that in the subjects with normal blood pressure. However, the systolic pressure gradient was greater in the hypertensive patients than in the control group both when the individuals were heated and when they were cooled.


1979 ◽  
Vol 57 (s5) ◽  
pp. 325s-327s ◽  
Author(s):  
E. Ambrosioni ◽  
F. Tartagni ◽  
L. Montebugnoli ◽  
B. Magnani

1. Intralymphocytic sodium concentration was measured in 50 patients with essential stable hypertension, 44 patients with labile hypertension and 40 subjects with normal blood pressure. 2. Intralymphocytic sodium concentration in normotensive subjects was significantly lower than in the other two groups. 3. The concentration was significantly correlated with mean blood pressure in the group as a whole and in the groups with stable and with labile hypertension. No correlation was found in normal subjects.


2020 ◽  
Vol 11 (2) ◽  
pp. 2614-2619
Author(s):  
Elsa Mathew ◽  
Mukkadan J. K.

Studies have evaluated that high blood pressure kills nine million people annually Persistent. Psychological factors can be considered as a primary threat to the increase of hypertension. It may lead to cardiovascular disease, stroke and kidney disease. The current work was conducted to analyze the disparity of anxiety, dyslipidemia and oxidative stress in pre-hypertensive and hypertensive subjects. This was a cross-sectional study conducted among 180 subjects. Based on the Joint National Committee 8 Criteria, participants were divided into hypertensive patients (n₌60) and pre-hypertensive patients (n₌63). Fifty-seven healthy subjects with normal blood pressure were served as the control group. Anthropometric measurements and blood pressure were measured using the standard procedure. The biochemical parameters for measuring oxidative stress, blood glucose levels, and lipid profile were estimated. Anxiety level was assessed with the State-trait anxiety inventory (STAI) questionnaire. It is observed that the serum MalonDiAldehyde (MDA) levels (nmol/ml) were significantly higher in pre-hypertensive (3.74±0.33) and hypertensive (4.7±0.38) compared to normotensive subjects (3.05±0.38). The Superoxide Dismutase (SOD) activity (U/ml) was higher in subjects with normal blood pressure (12.67±2.31) than pre-hypertensive (11.16±2.43) and hypertensive subjects (8.98±2.32). The MDA had a significant positive correlation, and SOD had a negative association with waist-hip ratio, systolic blood pressure, diastolic blood pressure, fasting blood sugar, high-density lipoprotein, and state and trait anxiety. The present study confirmed that pre-hypertensive and hypertensive subjects suffered from more oxidative stress than normotensive subjects.


2014 ◽  
Vol 7 (1) ◽  
pp. 930 ◽  
Author(s):  
Hadiza Saidu ◽  
Kamilu Karaye ◽  
Basil N Okeahialam

Biomedicine ◽  
2021 ◽  
Vol 41 (1) ◽  
pp. 88-92
Author(s):  
Anahita R. Shenoy Basti ◽  
M Shrilakshmi ◽  
Ram Shenoy Basti

Introduction and Aim: Increased carotid artery intima media thickness (CIMT) has been linked to the development of cardiovascular disease (CVD). CVD is a major cause of mortality and morbidity in India. Increased CIMT has been documented in Hypertension (HT), thus putting them at a higher risk of CVD. Early identification and awareness of risk factors leading to increased morbidity and mortality could help in reducing its incidence. The aim of the study was to measure CIMTin prehypertensive Indian population.   Materials and Methods:In this analytical observational study, common carotid artery IMT was measured using B mode ultrasonography in 46 individuals having blood pressure in the prehypertensive range and 46 individuals with normal blood pressure. Cardiovascular risk factors like body mass index(BMI),fasting blood glucose (FBS), and lipid profile, which are known to influence CIMT,were also assessed and compared between the two groups.   Results:CIMT was significantly higher in prehypertensives as compared to subjects having normal blood pressure. BMI, FBS, and lipid profile was found to be comparable between the two groups.   Conclusions:The presence of increased CIMT in prehypertensives as compared to controls indicates an increased risk of adverse cardiovascular events.


2021 ◽  
Vol 15 (5) ◽  
pp. 1474-1478
Author(s):  
B. Akhtar ◽  
H. Ishaq ◽  
M. T. Raza ◽  
M. Ismail ◽  
I. E. Soomro ◽  
...  

Aim: To compare the incidence of in-hospital complications between diabetic normotensive and hypertensive diabetic patients presenting with acute myocardial infarction (MI) Methodology: This observational cohort study was conducted at National Institute of Cardiovascular Diseases Karachi from May 2019 to April 2020. We examined 220 diabetics with acute MI were included. 50% of the patients had high blood pressure and the rest had normal blood pressure. After enrollment in the study, selectees were observed for acute myocardial infarction complications in the hospital. Results: Most of the baseline characteristics were similar in both groups of patients. However, the hypertensive patients in the diabetes group had diabetes, high heart rate, and high blood pressure at reporting. The complication rates did not differ statistically between the two groups. The rates of complications occurred between diabetes and normotensive hypertension; Atrial fibrillation (AF) 15.5% vs 12.7% p = 0.194, respectively, ventricular tachycardia (LH) 14.5% vs 13.6%, AV block type-1 8.2% vs 7.3% p = 0.296, type2 AV block 2.7% vs 1.8% p = 0.352, complete heart block 11.8% vs 10% p = 0.313, acute congestive heart failure (CHF) 13.6% VS% 9.1 p = 0.137, left ventricular failure (LVF)19.1% vs 16.4% p = 0.259, cardiogenic shock (CS) 14.5% vs 10.9% p = 0.184, recurrent IM (Re-MI) 14.5% 10.9% p = 0.184 and mortality 14.5% vs 12.7 and% p = 0.326, respectively. Conclusion:It is concluded that diabetic patients with hypertensionhave not elevated risk of complications in the hospital after acute myocardial infarction. Key words: diabetes, hypertension, hospital complications, acute myocardial infarction


1958 ◽  
Vol 36 (1) ◽  
pp. 889-893 ◽  
Author(s):  
P. Gaskell ◽  
A. M. Krisman

The brachial and digital blood pressures were estimated by auscultatory techniques in 10 patients with essential hypertension and in a group of 6 subjects with normal blood pressure who were in a state of regulated peripheral vasoconstriction and again when they were in a state of regulated vasodilatation. The brachial to digital systolic and diastolic pressure gradients in both control subjects and hypertensive patients were greater when the individuals were heated than when they were cooled. The brachial to digital diastolic pressure gradient in the hypertensive patients was not significantly different from that in the subjects with normal blood pressure. However, the systolic pressure gradient was greater in the hypertensive patients than in the control group both when the individuals were heated and when they were cooled.


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