scholarly journals Potential Use of Saraca Asoca in the Management of Artavadushti w.s.r. to Menstrual Disorders in Modern Era

Author(s):  
Sushma ◽  
L.P. Yadava

Progress of a family depends on health of women in the family because she is the only creature who has amazing power of creation. A woman suffers from various menstrual disorders (Artavadushti) in her life span. Ashoka (Saraca indica or Saraca asoca (Roxb.), belonging to the family Caesalpinioideae, is one of the most important herb extensively used in bleeding disorders in women throughout her active reproductive period. Ashoka means no grief in Sanskrit language. So it is also called as “friend of women” because it has reputation of its bark for retaining a woman healthy and youthful. Chemically, it contains glycosides, flavonoids, tannins and saponins. Its actions are spasmogenic, uterotonic, oxytocic, antibacterial, antit-umour, anti-implantations, anti-progestational and anti-estrogenic to fight against menorrhagia, leucorrhoea and anticancer. In view of these properties and also its Rasa, Guna, Veerya, Vipaka it can be used in the treatment of bleeding gynaecological diseases.

Author(s):  
Antonio Girolami ◽  
Diana Noemi Garcia de Paoletti ◽  
Marcelo Leonardo Nenkies ◽  
Silvia Ferrari ◽  
Hugo Guglielmone

Background: Investigation of rare bleeding disorders in Latin-America. Objective: The report of a new case of FX deficiency due to a compound heterozygosis. Methods: Accepted clotting procedures were used. Sequencing of DNA was carried out by means of Applied Biosystems Instruments. Results: A compound heterozygote due to the association of a new mutation (Gla72Asp) with an already known mutation (Gly154Arg) of the FX gene is reported. The proposita is a 38 year old female who had a moderate bleeding tendency (menorrhagia, epistaxis, easy bruising). The proposita has never received substitution therapy but in the occasion of a uterine biopsy. The mother was asymptomatic but was a heterozygote for the new mutation. The father was asymptomatic but had deserted the family and could not be investigated. After this abandonment the mother of the proposita re-married with an asymptomatic man and she gave birth to a son who was asymptomatic but was also heterozygous for the new mutation (Gla72Asp). As a consequence it has to be assumed that the first husband of the mother of the proposita was heterozygous for the known mutation (Gly154Arg). Conclusion: This is the third case of a new mutation in the FX gene reported, during the past few years, in Argentina.


Author(s):  
Gabriele Stephan ◽  
Niklas Ravn-Boess ◽  
Dimitris G Placantonakis

Abstract Members of the adhesion family of G protein-coupled receptors (GPCRs) have received attention for their roles in health and disease, including cancer. Over the past decade, several members of the family have been implicated in the pathogenesis of glioblastoma. Here, we discuss the basic biology of adhesion GPCRs and review in detail specific members of the receptor family with known functions in glioblastoma. Finally, we discuss the potential use of adhesion GPCRs as novel treatment targets in neuro-oncology.


KIRYOKU ◽  
2021 ◽  
Vol 5 (2) ◽  
pp. 283-300
Author(s):  
Sri Sudarsih

The purpose of this study is to explore traditional moral values in Japanese society that are able to survive and be implemented in everyday life in the modern era. In addition, it is able to shape the distinctive character of the Japanese, including the role of women who contribute to maintaining traditional moral values. This research is a qualitative research field of philosophy with the object of formal values and the material object is the development of women's position in Japanese society. The results achieved in the study: Japanese women played an important role in the history of the struggle until Japan achieved prosperity and glory until now. This is based on the reason that Japanese women are able to maintain and preserve traditional moral values that still exist through early education in the family environment. These values can shape the character of children from an early age in the family. A family with character brings logical consequences to the life of a community with character so that it affects the culture as a whole.


Author(s):  
YA.YU. GOLIVANOV ◽  
◽  
V.V. ZELENENKO ◽  
V.V. GRITSENKO

The article presents data on the assessment of some issues of the ontogenesis of the bird cherryoat aphid: the average life expectancy, the number of offspring over a lifetime, the beginning of the reproductive period, the end of the reproductive period, the duration of the reproductive period, the life span of aphids and the number of offspring. The author found that the average life expectancy of animals was 21.55 days. The beginning of the reproductive period, on average, was on days 7–8, the end – on day 19. The average duration of the reproductive period was 12.5 days. The average number of offspring over the entire life for individuals in the sample was 34 nymphs, in a separate litter – 2–3 nymphs.


2019 ◽  
Vol 22 (1) ◽  
pp. 109-116 ◽  
Author(s):  
Nargis Sultana Chowdhury ◽  
Farhana Farjana ◽  
Sifat Jamaly ◽  
Mst Nadira Begum ◽  
Mst Elina Akhter Zenat

Devil’s cotton (Ulatkambal) is a genus in the family Malvaceae, with one or two species from Asia and Australia. Literature review revealed that Abroma augusta (Devil’s cotton) is widely used in Ayurvedic medicine as a popular drug. Devil’s cotton has been claimed to possess major biological activities like anti-diabetic, analgesic, anti-inflamatory, thrombolytic, antioxidant, hypolipidemic etc. They are also utilized by the traditional local healers of different Asian countries to treat various diseases like diabetes mellitus, as uterine tonic in emmerogogue, dysmenorrhea, amenorrhoea, sterility and other menstrual disorders, rheumatic pains of joints and headache with sinusitis. Biochemical profiling of different parts of the plant demonstrated the presence of some important phytochemicals like alkaloids, abromin, sterol, friedelin, abromasterol, taroxerylacetate, taraxeral and β-sitosterol. The aim of this review was to analyze the published report based on the medicinal values of Devil’s cotton species as well to provide the updated information about the ethnomedicinal, pharmacological as well as the phytochemical properties. Bangladesh Pharmaceutical Journal 22(1): 109-116, 2019


2020 ◽  
Vol 6 (4) ◽  
pp. 463-487
Author(s):  
Ryan W. Scott ◽  
Suzanne E. Tank ◽  
Xiaowa Wang ◽  
Roberto Quinlan

Aquatic habitats in the Canadian Arctic are expected to come under increasing stress due to projected effects of climate change. There is a need for community-based biomonitoring programs to observe and understand the effects of these stressors on the environment. Here we present results from a 5 year annual sampling program of benthic invertebrates from lakes in the Mackenzie Delta, Northwest Territories, using a rapid bioassessment protocol. Connectivity between the deltaic lakes and main channels is a major driver of lake function and is expected to be substantially impacted by climate change. Lakes were selected along a gradient of connectivity based on sill elevation above the river. Using multivariate analyses of community structure, we determined that benthic assemblages responded to differences in connection time among lakes. This response was detected using a coarse taxonomic level that could be applied by community groups or volunteers but was stronger when invertebrates were identified to the family and genus levels. A secondary gradient was observed that corresponded to productivity gradients in lakes that are isolated from the river during summer. We show that benthic assemblages have potential use as sensitive indicators of climate-mediated changes to the hydrology of lakes in the Mackenzie Delta.


2000 ◽  
Vol 113 (19) ◽  
pp. 3355-3356
Author(s):  
S.D. Shapiro

Matrix Metalloproteinases and TIMPs by J. Frederick Woessner and Hideaki Nagase Oxford University Press (2000) pp. 223. ISBN 0–19-850268-0 35.00 Ever since Gross discovered that collagenase was responsible for resorption of the tadpole tail, there has been a small group of outstanding scientists that have dedicated their careers to the study of matrix metalloproteinases (MMPs). The family of MMPs has now grown to over 20, and they have been implicated in multiple biological processes drawing the attention of scientists of many disciplines. Two leaders in the field who have ushered in the modern era of MMP biology are Fred Woessner and Hideake Nagase and they share their expertise in Matrix Metalloproteinases and TIMPs. In a concise, yet thorough manner, these authors provide the basic biochemical and biological basis for the study of MMPs. This information, laced with a strong sense of historical perspective, is conveyed in the same interesting manner in which they educated this reviewer and many others over late night scotch at MMP Gordon Conferences. For the interested novice, one will come away no longer needing a score card to keep track of MMP-1 through MMP-22 (perhaps more by now). One will understand which cells produce which MMPs and TIMPs in response to which stimuli. The reader will understand the multiple levels of regulation of MMP activity through gene transcription, proenzyme activation, and inhibition by TIMPs. The book is filled with readable tables depicting important concepts in classification, evolution, and substrate specificity. The authors provide extensive key references for further reading as only they can. The only area not extensively covered is the rapidly emerging in vivo function of MMPs that comes from transgenic and gene targeted mice and animal models. Perhaps this will be the sequel to this primer. As the biological role of these enzymes expands and it becomes more difficult for scientists to ignore MMPs, this book provides a meaningful and painless way to become fluent in the field. Upon completion of the text, readers will feel comfortable incorporating MMPs into their research endeavors. Hopefully this work will spark investigators to ask how these enzymes relate to one's own research interests thus broadening our general biological knowledge.


Author(s):  
Sinem Siyahhan ◽  
Elisabeth Gee

The family environment is an important social context where learning takes place for adults and children of all ages, and perhaps the only context in which participation occurs over a life-span. In this social context, playing games has always been one of many activities family members do individually and together that engages them in learning. In this chapter, we offer a broad perspective on learning and discuss how games of all sorts can provide opportunities for learning, and how families can take more advantage of these potential learning experiences.


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