scholarly journals Pharmacological aspects & medicinal uses of Trigonella foenum-graecum: A Current Review

2021 ◽  
Vol 12 (4) ◽  
pp. 776-786
Author(s):  
Veer Inder Singh ◽  
Rahul Kumar Sharma ◽  
Yogesh Kumar ◽  
Sadique Saqulain
Keyword(s):  
Chemical Constituents ◽  
Health Impact ◽  
Daily Basis ◽  
High Morbidity ◽  
Pharmaceutical Drugs ◽  
Long Term Conditions ◽  
Medicinal Uses ◽  
Trigonella Foenum Graecum ◽  
Serious Infections ◽  
Anti Oxidant

Globally a large number of people are affected by acute and chronic diseases resulting in high morbidity and mortality rate. A huge amount of pharmaceutical drugs are being manufactured on a daily basis to combat these diseases. But due to their high cost and deleterious effects, it becomes critically important to state emphasis on finding an alternative way to manage these long term conditions. Medicinal herbs could provide a good source of dietary supplement combined with existing therapies. Many scientific studies have demonstrated that medicinal plants and herbs have the potential for the treatment of many serious infections and many disorders. Out of these herbs, Fenugreek is recognized as an oldest herb with great medicinal potential. Fenugreek harbors many essential macronutrients and micronutrients along with trace elements. Numerous chemical constituents present in fenugreek highlights a variety of pharmacological activity such as anti-glycemic activity, anti-oxidant capacity, anti-inflammatory effects, hypocholesterolemic activity and many more. This article explores the diverse active compounds and potential pharmacological applications of Trigonella foenum-graecum also known as fenugreek. It also focuses on the medicinal significance and health impact of taking fenugreek in our day to day nutrition.

scholarly journals Pharmacognostic, phytochemical, physicochemical and TLC profile study Mace (Aril) of Myristica malabarica Lamk. (Myristicaceae)

2017 ◽  
Vol 6 (6) ◽  
pp. 329-334
Author(s):  
Seema Yuvraj Mendhekar ◽  
◽  
Chetana Dilip Balsaraf ◽  
Mayuri Sharad Bangar ◽  
SL Jadhav ◽  
...  
Keyword(s):  
Quality Control ◽  
Chemical Constituents ◽  
Western Ghat ◽  
Medicinal Uses ◽  
Crude Drug ◽  
Phytochemical Investigation ◽  
Anti Oxidant ◽  
Sedative Hypnotics ◽  
Profile Study

The plant Myristica malabarica Lamk. is traditionally used as a medicine and spices in food . It is belonging to family Myristicaceae. The plant is native to India and endangered trees are mostly found in western ghat. Extracted with various solvents by successive soxhlet hot extraction processs with increasing order of polarity on phytochemical investigation. The extract has shown alkaloids, saponin, tannin and flavones glycosides. It has important medicinal uses like Ayurvedic Medicines. It is traditionally used as anticancer, antiInflammatory, anti-Oxidant, Sedative hypnotics, Antimicrobial, Antifertility, Hepatoprotective and cytotoxicity. The chemical constituents such as Malabaricones, Malabaricanol, Isoflavones are isolated .Myristica Fragrans also known as fragnant Nutmeg or true Nutmeg. The present study i.e. Pharmacognostic, Phytochemical, Physicochemical and TLC Profile Study of Mace (Aril) Of Myristica malabarica Lamk. is helpful in the characterization of the crude drug. Physiochemical and phyto-chemical analysis of mace confirm the quality and purity of plant and its identification. The information collected is useful for further pharmacological and therapeutical evaluation of mace (Aril) Of Myristica malabarica Lamk. and anthology of quality control of crude drug.

scholarly journals A study to evaluate the preservative action of Twak Arka in Triphala Kwatha

2021 ◽  
Vol 12 (3) ◽  
pp. 513-517
Author(s):  
Rakshitha D ◽  
Neha Semwal ◽  
Gazala Hussain
Keyword(s):  
Shelf Life ◽  
Microbial Growth ◽  
Microbial Contamination ◽  
Chemical Constituents ◽  
Fungal Growth ◽  
Daily Basis ◽  
Dosage Forms ◽  
Carcinogenic Effects ◽  
Anti Oxidant ◽  
Natural Preservatives

Introduction: Primary dosage forms are basic preparations whose shelf life is a challenge for the practice. Kwatha is a preparation which is easily prone to contamination and can be marketed only by the addition of suitable preservatives to increase the shelf life. So addition of preservatives is being practiced to prolong the shelf life of kwatha but presently using chemical preservatives are harmful to body and even have carcinogenic effects. Hence there aroused a need to find natural preservatives. Arka which is a water distillate consists of essential substances from the crude drug and has longer shelf life. Twak arka possess anti- microbial and anti- oxidant properties and economically cheaper and easily available drug and triphala kwatha being useful in many purposes. In this study an attempt was made to elucidate the preservative action of twak arka in triphala kwatha. Materials and methods: Includes preparation of twak arka, triphala kwatha and conduction of analytical and microbiological study to see the preservative action using SDA and MHA media. Observations and results: Study follows observations over microbial growth of the sample on daily basis where twak arka showed preservative action for 31 days. Aspergillus niger was the fungal growth seen on 32nd day. Discussion: Twak arka owing to its pH, chemical constituents and other properties preserved the triphala kwatha for a stipulated period of time. Conclusion: From the study, it was concluded that the twak arka preserved triphala kwatha without any microbial contamination for 31 days which was added in the concentration of 15%.

scholarly journals A REVIEW ON PHARMACOLOGICAL ACTIVITIES OF POLYALTHIA LONGIFOLIA L

2021 ◽  
pp. 172-177
Author(s):  
Dhiren k Vaghela ◽  
Dhruv Pandya ◽  
Hitesh Solanki
Keyword(s):  
Antimalarial Activity ◽  
Chemical Constituents ◽  
Antiulcer Activity ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Plant Parts ◽  
Ornamental Tree ◽  
Anti Oxidant ◽  
Polyalthia Longifolia

Polyalthia longifolia L. is an ornamental tree (mostly used as an avenue tree) which belongs to Annonaceae. As per the review of the research papers it also has so many important chemical constituents in its different parts. These chemicals are alkaloids, flavonoids, phenols, terpenoids and essensial oil etc that can be used for the preparation of different medicines for several diseases. In this review authors focused on the pharmacological properties and ethnomedicinal properties of the plant parts and their implementation in the pharmacological science. The plant part different extracts showed different types of pharmacological activities like Antibacterial activity, Antifungal activity, Antitumor (Anticancer activity), cytotoxic activity, Anti-oxidant activity, Anti-inflammatary activity, Antimalarial activity and Antiulcer activity. Even the plant also has so many traditional medicinal uses. So, its not just an ornamental tree but it can be good resourse for the secondary metabolites and considered as medicinally important plant.

In-vivo evaluation of lipid lowering ability of Chloris paraguaiensis extracts

2020 ◽  
Vol 7 (2) ◽  
pp. 21-24
Author(s):  
Pavani C H
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
The Body ◽  
Lipid Lowering ◽  
Medical Systems ◽  
In Vivo Evaluation ◽  
Standard Drug ◽  
Anti Oxidant ◽  
And Control

Hyperlipidemia is the immediate results of the excessive fat intake in food. This results in the elevated levels of cholesterol and triglycerides in the blood. This leads to heart conditions like CAD, hypertension, congestive heart failure as risk factors which can be lethal. There are many drugs to treat and control the lipids levels in the body. These drugs are either designed to prevent LDL accumulation and VLDL synthesis. Some drugs also lower the elevated levels of saturated lipids in the body. But many drugs are known to cause side effects and adverse effects; therefore, alternatives to the drugs are the subjects for current investigations. Herbs and medicinal plants are used as treatment sources for many years. They have been used in the Indian medical systems like Ayurveda, Siddha etc. As the application of herbs in the treatment is growing, there is an urgent need for the establishment of Pharmacological reasoning and standardization of the activity of the medicinal plants. Chloris paraguaiensis Steud. is Poyaceae member that is called locally as Uppugaddi. Traditionally it is used to treat Rheumatism, Diabetes, fever and diarrhoea. The chemical constituents are known to have anti-oxidant properties and most of the anti-oxidants have anti-hyperlipidemic activity too. Since the plant has abundant flavonoid and phenol content, the current research focusses on the investigation of the anti-hyperlipidemic activity of the plant Chloris extracts. Extracts of Chloris at 200mg/kg showed a comparably similar anti hyperlipidemia activity to that of the standard drug. The extracts showed a dose based increase in the activity at 100 and 200mg/kg body weight.

Pharmacognostical and pharmacological activity of Justicia gendarussa burm.f.: a comprehensive review

2020 ◽  
Vol 11 (3) ◽  
pp. 3384-3390
Author(s):  
Ashish ◽  
Anjali ◽  
Dixit Praveen K ◽  
Nagarajan K ◽  
Sahoo Jagannath
Keyword(s):  
Pharmacological Activity ◽  
Chemical Constituents ◽  
Biological Action ◽  
Andaman Islands ◽  
Comprehensive Review ◽  
Medicinal Value ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Pharmacologically Active ◽  
Different Parts

Justicia gendarussa Burm .f. (family Acanthaceae) which is also known as willow-leaves and commonly known as Nili-Nirgundi, it is very commonly found nearby to China and its availability is very common in larger parts of India and Andaman islands. Traditionally it is used to treat various sorts of disorders such as wound healing, anti-inflammatory, anti-oxidant, antiproliferative, anti-arthritic etc. Justicia gendarussa is one of the crucial herbs which has been used in the Ayurveda. Majorly leaves parts of the plant shows the pharmacological activity but the root of the plant Justicia gendarussa is also have the important medicinal values. A large variety of pharmacologically active constituents i.e., alkaloids, flavonoids, saponin, carbohydrates, steroids, triterpenoids, carotenoids, aminoacids, tannins, phenolics, coumarines and anthaquinones are also present in this plant and they makes the plant pharmacologically important. The activity of the plant is also dependent on the solvent which is used for the extraction the various vital chemical constituents. The different- different parts of the plants having the different medicinal values also differ in the chemical values. This review is not only focused on the essential phytochemical constituents which is available in the plant but it also explains their necessary medicinal value to shows the essential biological action and phytopharmacological actions of various parts of the plant.

Phytochemical, Pharmacological Activities and Ayurvedic Significances of Magical Plant Mimosa pudica Linn

2020 ◽  
Vol 17 ◽  
Author(s):  
Vijay Kumar
Keyword(s):  
Therapeutic Potential ◽  
Wide Spectrum ◽  
Chemical Constituents ◽  
Future Research ◽  
Mimosa Pudica ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Crude Extracts ◽  
Anti Cancer

: Mimosa pudica Linn is an integrated part of Traditional Medicines Systems of India, China, Africa, Korea and America. It has been used from centuries in traditional medicines to cure different diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, and dyspepsia. It is an important ingredient of wide class of herbal formulations. To assess the scientific evidence for therapeutic potential of Mimosa pudica Linn and to identify the gaps for future research. The available information on the ethno-medicinal uses, phytochemistry, pharmacology and toxicology of Mimosa pudica Linn was collected via a library and electronic searches in Sci-Finder, Pub-Med, Science Direct, Google Scholar for the period, 1990 to 2020. In traditional medicinal systems, variety of ethno-medicinal applications of Mimosa pudica Linn has been noticed. Phytochemical investigation has resulted in identification of 40 well known chemical constituents, among which alkaloids, phenols and flavionoids are the predominant groups. The crude extracts and isolates have exhibited a wide spectrum of in vitro and in vivo pharmacological activities including anti-cancer, anti-inflammation, osteoporosis, neurological disorders, hypertension etc.. To quantify the Mimosa pudica Linn and its formulations, analytical techniques like HPLC and HPTLC has shown dominancy with good range of recovery and detection limit. Mimosa pudica Linn is the well-known herb since an ancient time. The pharmacological results supported some of the applications of Mimosa pudica Linn in traditional medicine systems. Perhaps, the predominance of alkaloids, phenols and flavionoids are responsible for the pharmacological activities the crude extracts and isolates of Mimosa pudica Linn. Further, there is need to isolate and evaluate the active chemical constituents of Mimosa pudica Linn having significant medicinal values. In future, it is important to study the exact mechanism associated with the phytochemicals of Mimosa pudica Linn especially on anti-cancer activities. Notably, toxicity studies on Mimosa pudica Linn are limited which are to be explored in future for the safe application of Mimosa pudica Linn and its formulations.

A Review of Phytochemical and Pharmacological Studies of Inula Species

2020 ◽  
Vol 16 (5) ◽  
pp. 557-567
Author(s):  
Aparoop Das ◽  
Anshul Shakya ◽  
Surajit Kumar Ghosh ◽  
Udaya P. Singh ◽  
Hans R. Bhat
Keyword(s):  
Bacterial Infections ◽  
Chemical Constituents ◽  
Valuable Insight ◽  
Important Ingredient ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
The Family ◽  
Pharmacological Studies ◽  
Perennial Herbs ◽  
Insight Into

Background: Plants of the genus Inula are perennial herbs of the family Asteraceae. This genus includes more than 100 species, widely distributed throughout Europe, Africa and Asia including India. Many of them are indicated in traditional medicine, e.g., in Ayurveda. This review explores chemical constituents, medicinal uses and pharmacological actions of Inula species. Methods: Major databases and research and review articles retrieved through Scopus, Web of Science, and Medline were consulted to obtain information on the pharmacological activities of the genus Inula published from 1994 to 2017. Results: Inula species are used either alone or as an important ingredient of various formulations to cure dysfunctions of the cardiovascular system, respiratory system, urinary system, central nervous system and digestive system, and for the treatment of asthma, diabetes, cancers, skin disorders, hepatic disease, fungal and bacterial infections. A range of phytochemicals including alkaloids, essential and volatile oils, flavonoids, terpenes, and lactones has been isolated from herbs of the genus Inula, which might possibly explain traditional uses of these plants. Conclusion: The present review is focused on chemical constituents, medicinal uses and pharmacological actions of Inula species and provides valuable insight into its medicinal potential.

The Valuable Impacts of Halophytic Genus Suaeda; Nutritional, Chemical, and Biological Values

2020 ◽  
Vol 16 (8) ◽  
pp. 1044-1057 ◽  
Author(s):  
Hamdoon A. Mohammed
Keyword(s):  
Search Engines ◽  
Scientific Literature ◽  
High Salinity ◽  
Chemical Constituents ◽  
Harsh Environment ◽  
Science Literature ◽  
Medicinal Uses ◽  
Nutritional Values ◽  
Alternative Medicines ◽  
Natural Substances

Background: Suaeda is a halophytic genus belonging to the Amaranthaceae family and can survive in the high salted marsh areas of the world. Suaeda plants can biosynthesize natural substances with powerful antioxidant activity and are considered as a renewable source of energy, food, and edible oil for a larger number of populations living in the harsh environment with high salinity and drought conditions. These plants also meet folk and alternative medicines' needs. Methods: The review encompasses available scientific literature related to folk medicinal uses of Suaeda plants, their nutritional values, and chemical constituents. In addition, the biological trials applied for the Suaeda plants are also part of the review. The review covers the researches from major science literature search engines and other sites representing scientific literature, i.e., Scifinder, Google Scholar, PubMed, ScienceDirect, Scopus, and Google. The searches were programmed on the advance options available in the search engines and are latest up to November 2019. The searches were exhaustive and rechecked for accuracy. Conclusion: The study summarizes the uses of Suaeda plants as a remedy for various ailments due to their contents from the polyphenols and flavonoids. The comparatively large amounts of fixed oils, minerals, and vitamins in Suaeda plants have also made them potential renewable sources for foods.

Namibian algae species: A review of their distribution, medicinal uses and chemical constituents

2020 ◽  
pp. 1-21
Author(s):  
Ateeq Rahman ◽  
Moola M. Nyambe ◽  
Jan-Heiner Küpper
Keyword(s):  
Neglected Tropical Diseases ◽  
Chemical Constituents ◽  
Structural Diversity ◽  
New Drugs ◽  
African Countries ◽  
New Agents ◽  
Medicinal Uses ◽  
Defense Strategies ◽  
Underdeveloped Countries ◽  
Popular Knowledge

The use of indigenous or remote popular knowledge to identify new drugs against diseases or infections is a well-known approach in medicine. The inhabitants of coastal regions in Namibia and other African countries are known to prepare algae extracts for the treatment of disorders and ailments such as wounds, fever and stomach aches, as well as for the prevention of arrhythmia, cancer, and many other diseases. Algae survive in a competitive environment and, therefore, developed defense strategies that have resulted in a significant level of chemical structural diversity in various metabolic pathways. The exploration of these organisms for pharmaceutical, nutritional and medical purposes has provided important chemical candidates for the discovery of new agents against neglected tropical diseases and stimulated the use of sophisticated physical techniques. This current review provides a broad picture on the taxonomy, various medical and nutritional uses of algae, which thus should be of relevance for the African continent and underdeveloped countries in the Global South.

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