Narrow band imaging and autofl uorescence in orofaryngeal carcinoma diagnostics

2021 ◽  
Vol 70 (1) ◽  
pp. 32-38
Author(s):  
Jaroslav Sýba ◽  
Petr Lukeš ◽  
Lucie Dostálová ◽  
Martin Chovanec ◽  
Jan Plzák

Despite progress in the treatment of head and neck cancer, the five-year overall survival rate is still low because of late dia­gnosis. The head and neck mucosal tumours were usually dia­gnosed in higher stages in past, therefore new endoscopic optical imaging methods were developed for better and earlier detection of these lesions. They are divided in two main groups – horizontal and vertical methods. The horizontal ones show the surface of the mucous membrane (narrow band imaging, autofluorescence, photodynamic dia­gnosis, magnifying and contact endoscopy). The vertical ones show different layers of the mucosa (optical coherence tomography and confocal endomicroscopy). Narrow band imaging and autofluorescence endoscopy are already used routinely in foreign countries, magnifying and contact endoscopy are getting to practice recently. The authors present a summary of narrow band imaging and autofluorescence endoscopy usage in the dia­gnostics of oropharyngeal carcinoma.

2006 ◽  
Vol 24 (7) ◽  
pp. 1064-1071 ◽  
Author(s):  
David J. Adelstein ◽  
Jerrold P. Saxton ◽  
Lisa A. Rybicki ◽  
Ramon M. Esclamado ◽  
Benjamin G. Wood ◽  
...  

Purpose A retrospective review with long-term follow-up is reported from the Cleveland Clinic Foundation studying radiation and concurrent multiagent chemotherapy in patients with locoregionally advanced squamous cell head and neck cancer. Patients and Methods Between 1989 and 2002, 222 patients were treated with 4-day continuous infusions of fluorouracil (1,000 mg/m2/d) and cisplatin (20 mg/m2/d) during weeks 1 and 4 of either once daily or twice daily radiation therapy. Primary site resection was reserved for patients with residual or recurrent primary site disease after chemoradiotherapy. Neck dissection was considered for patients with N2 or greater disease, irrespective of clinical response, and for patients with residual or recurrent neck disease. Results With a median follow-up of 73 months, the Kaplan-Meier 5-year projected overall survival rate is 65.7%, freedom from recurrence rate is 74.0%, local control without the need for surgical resection rate is 86.7%, and overall survival rate with organ preservation is 62.2%. Including patients undergoing primary site resection as salvage therapy, the overall local control rate is 92.4%. Regional control rate at 5 years is 92.4%. Among patients with N2-3 disease, regional control was significantly better if a planned neck dissection was performed. Distant control at 5 years was achieved in 85.4% of patients and was significantly worse in patients with hypopharyngeal primary sites and patients with poorly differentiated tumors. Conclusion Concurrent multiagent chemoradiotherapy can result in organ preservation and cure in the majority of appropriately selected patients with locoregionally advanced, nonmetastatic, squamous cell head and neck cancer. Distant metastatic disease was the most common cause of treatment failure. Late functional outcomes will require further investigation.


Head & Neck ◽  
2012 ◽  
Vol 35 (5) ◽  
pp. 619-625 ◽  
Author(s):  
Phan Nguyen ◽  
Farzad Bashirzadeh ◽  
Robert Hodge ◽  
Julie Agnew ◽  
Camile S. Farah ◽  
...  

2012 ◽  
Vol 50 (2) ◽  
pp. 132-136 ◽  
Author(s):  
Neil C.-W. Tan ◽  
M. Kerry Herd ◽  
Peter A. Brennan ◽  
Roberto Puxeddu

2015 ◽  
Vol 48 (2) ◽  
pp. 142 ◽  
Author(s):  
Hsin-Jen Chang ◽  
Wen-Hung Wang ◽  
Yen-Liang Chang ◽  
Tzuan-Ren Jeng ◽  
Chun-Te Wu ◽  
...  

2014 ◽  
Vol 04 (02) ◽  
pp. 059-063
Author(s):  
Sonika Achalli ◽  
Medhini Madi ◽  
Subhas G. Babu ◽  
Shishir Ram Shetty

Abstract:Narrow Band Imaging (NBI) is a recent method of imaging which can be used as an adjunctive diagnostic device along with standard diagnostic protocol. This technology will improve clinicians' ability to detect early changes in inflammatory and dysplastic tissues. Recently there has been a rapid progression in its use in patients with head and neck cancer. NBI system is based on the principle of producing blue light which penetrates less deeply into the tissues of precancerous and cancerous lesions when compared to that of conventional white light and thus helps clinicians' to get a much better view of superficial structures.


2016 ◽  
Vol 127 (7) ◽  
pp. 1577-1582 ◽  
Author(s):  
Robert Šifrer ◽  
Jure Urbančič ◽  
Primož Strojan ◽  
Aleksandar Aničin ◽  
Miha Žargi

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